Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | Q521H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S420C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V330V | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q326E | Missense | 1 |
| CESC | Cervical and endocervical cancers | A238S | Missense | 1 |
| CESC | Cervical and endocervical cancers | F131L | Missense | 1 |
| COAD | Colon adenocarcinoma | C73C | Silent | 1 |
| COAD | Colon adenocarcinoma | D307N | Missense | 1 |
| COAD | Colon adenocarcinoma | E157E | Silent | 1 |
| COAD | Colon adenocarcinoma | E282E | Silent | 1 |
| COAD | Colon adenocarcinoma | E97Q | Missense | 1 |
| COAD | Colon adenocarcinoma | I22I | Silent | 1 |
| COAD | Colon adenocarcinoma | L113L | Silent | 1 |
| COAD | Colon adenocarcinoma | R268H | Missense | 1 |
| COAD | Colon adenocarcinoma | R492H | Missense | 1 |
| COAD | Colon adenocarcinoma | R599H | Missense | 1 |
| COAD | Colon adenocarcinoma | S380F | Missense | 1 |
| ESCA | Esophageal carcinoma | A241V | Missense | 1 |
| ESCA | Esophageal carcinoma | L283L | Silent | 1 |
| ESCA | Esophageal carcinoma | P186P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E414K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E541Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G84E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K441K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K473N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R399Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T38I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V144V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L4L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S579Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I278M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q221Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N33S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A2T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A318V | Missense | 1 |
| LUAD | Lung adenocarcinoma | E23D | Missense | 1 |
| LUAD | Lung adenocarcinoma | H452R | Missense | 1 |
| LUAD | Lung adenocarcinoma | I114K | Missense | 1 |
| LUAD | Lung adenocarcinoma | L87M | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q202E | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q464Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | T70T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V436A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K149N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q391E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q456R | Missense | 1 |
| READ | Rectum adenocarcinoma | A241V | Missense | 1 |
| SARC | Sarcoma | I31I | Silent | 1 |
| SARC | Sarcoma | K29N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H123Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R26W | Missense | 1 |
| STAD | Stomach adenocarcinoma | A241V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D100H | Missense | 1 |
| STAD | Stomach adenocarcinoma | E130D | Missense | 1 |
| STAD | Stomach adenocarcinoma | E91G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E97K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G46G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K509K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L498M | Missense | 1 |
| STAD | Stomach adenocarcinoma | L546L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R481W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R599C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T597A | Missense | 1 |
| THCA | Thyroid carcinoma | R355H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A592A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C126C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E405* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E91G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F310L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R36H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R502H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V306V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.8 | 4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 23.8 | 12 | 0 |
| ESCA | Esophageal carcinoma | 185 | 9.5 | 2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.5 | 12 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.8 | 2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.8 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.5 | 16 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2 | 0 |
| SARC | Sarcoma | 247 | 4.8 | 2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 14.3 | 18 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.3 | 8 | 100 |