Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | V701A | Missense | 6 |
| COAD | Colon adenocarcinoma | G723G | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | P747S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D402H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E137K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E187* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E643D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F339L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1088G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I1004I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I252M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L260L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P65S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P758L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P812T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1070* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R116I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S682* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S7F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S821* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T197A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V909V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Y1045H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E980K | Missense | 1 |
| BRCA | Breast invasive carcinoma | F494L | Missense | 1 |
| BRCA | Breast invasive carcinoma | L545F | Missense | 1 |
| BRCA | Breast invasive carcinoma | P792L | Missense | 1 |
| BRCA | Breast invasive carcinoma | P807P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R20I | Missense | 1 |
| BRCA | Breast invasive carcinoma | S908L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1021K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E137Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E980K | Missense | 1 |
| COAD | Colon adenocarcinoma | A1035V | Missense | 1 |
| COAD | Colon adenocarcinoma | A202V | Missense | 1 |
| COAD | Colon adenocarcinoma | A386A | Silent | 1 |
| COAD | Colon adenocarcinoma | A679A | Silent | 1 |
| COAD | Colon adenocarcinoma | A924T | Missense | 1 |
| COAD | Colon adenocarcinoma | D706N | Missense | 1 |
| COAD | Colon adenocarcinoma | E712K | Missense | 1 |
| COAD | Colon adenocarcinoma | E980K | Missense | 1 |
| COAD | Colon adenocarcinoma | G208G | Silent | 1 |
| COAD | Colon adenocarcinoma | G418E | Missense | 1 |
| COAD | Colon adenocarcinoma | G418W | Missense | 1 |
| COAD | Colon adenocarcinoma | G443C | Missense | 1 |
| COAD | Colon adenocarcinoma | K687N | Missense | 1 |
| COAD | Colon adenocarcinoma | K687Q | Missense | 1 |
| COAD | Colon adenocarcinoma | N1030I | Missense | 1 |
| COAD | Colon adenocarcinoma | N574H | Missense | 1 |
| COAD | Colon adenocarcinoma | P758P | Silent | 1 |
| COAD | Colon adenocarcinoma | R354C | Missense | 1 |
| COAD | Colon adenocarcinoma | S427S | Silent | 1 |
| COAD | Colon adenocarcinoma | S711S | Silent | 1 |
| COAD | Colon adenocarcinoma | T1129T | Silent | 1 |
| COAD | Colon adenocarcinoma | T651A | Missense | 1 |
| COAD | Colon adenocarcinoma | T881M | Missense | 1 |
| ESCA | Esophageal carcinoma | P72T | Missense | 1 |
| ESCA | Esophageal carcinoma | Q181R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L410L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P72L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P72P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S655S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S676S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S908L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T1171M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T784M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y602H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K1024E | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P107T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P430S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V543G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E187E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q394Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1029S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1029V | Missense | 1 |
| LUAD | Lung adenocarcinoma | C209F | Missense | 1 |
| LUAD | Lung adenocarcinoma | D184Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | D659Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | F357C | Missense | 1 |
| LUAD | Lung adenocarcinoma | F468F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G421V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I252I | Silent | 1 |
| LUAD | Lung adenocarcinoma | K1023* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | P653A | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q174L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q871L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R86P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1092I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F459L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I3I | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S385S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S472G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S882S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | A477A | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | A484T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K687N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1002R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R961C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T1109T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | V177I | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A305T | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A305V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1029T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | F89L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P430L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P812P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R431H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R803M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T751M | Missense | 1 |
| READ | Rectum adenocarcinoma | K204N | Missense | 1 |
| READ | Rectum adenocarcinoma | N400I | Missense | 1 |
| READ | Rectum adenocarcinoma | Q1087* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | V701A | Missense | 1 |
| SARC | Sarcoma | G301R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E646K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E759D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H95Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1004I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K928M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1174R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P65L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P699S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P757L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P757S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P82S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R422C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R522* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1085S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1091S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S155F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S425F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S589L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T786T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W1041* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A386V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A461V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A990V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C1062* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | C271Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | E531V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E712K | Missense | 1 |
| STAD | Stomach adenocarcinoma | I151T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K265Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q1017R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R724W | Missense | 1 |
| STAD | Stomach adenocarcinoma | T455M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T881M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V177I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V584A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G704G | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S472R | Missense | 1 |
| THCA | Thyroid carcinoma | S488S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A631V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A794T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A916T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A924T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C130C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D716Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E534K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E618D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E874D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E980K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K265E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1145R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R306R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R553H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R553P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1091S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1092N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1170N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S33S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V177I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 10 | 9.2 | 44.4 |
| BRCA | Breast invasive carcinoma | 976 | 2.5 | 4.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 22.5 | 16.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10 | 3.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5 | 9.2 | 11.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.5 | 1.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.5 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 5 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.5 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.5 | 4.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.3 | 11.1 |
| SARC | Sarcoma | 247 | 0 | 0.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 10 | 12.3 | 22.2 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.8 | 11.1 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.5 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 2.5 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 11.5 | 0 |