microRNA information: hsa-miR-1296-5p
| Section | ID | link |
|---|---|---|
| Mature name: | hsa-miR-1296-5p | miRbase |
| Accession: | MIMAT0005794 | miRbase |
| Precursor name: | hsa-mir-1296 | miRbase |
| Precursor accession: | MI0003780 | miRbase |
| Symbol: | MIR1296 | HGNC |
| RefSeq ID: | NR_031566 | GenBank |
| Sequence: | UUAGGGCCCUGGCUCCAUCUCC |
Reported expression in cancers: hsa-miR-1296-5p
| miRNA | cancer | regulation | reporting | PUBMED | method |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | prostate cancer | downregulation | "Regulation of minichromosome maintenance gene fami ......" | 20332239 |
Reported cancer pathway affected by hsa-miR-1296-5p
| miRNA | cancer | pathway | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | breast cancer | cell cycle pathway; Apoptosis pathway | "Tumor suppressor role of microRNA 1296 in triple n ......" | 26799586 | Colony formation; Luciferase |
| hsa-miR-1296-5p | prostate cancer | cell cycle pathway | "Regulation of minichromosome maintenance gene fami ......" | 20332239 | RNAi |
Reported cancer prognosis affected by hsa-miR-1296-5p
| miRNA | cancer | prognosis | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | colon cancer | staging | "We assessed by qRT-PCR expression of 754 microRNAs ......" | 27485175 |
Reported gene related to hsa-miR-1296-5p
| miRNA | cancer | gene | reporting | PUBMED |
|---|---|---|---|---|
| hsa-miR-1296-5p | breast cancer | CCND1 | "miR-1296 overexpression significantly suppressed t ......" | 26799586 |
| hsa-miR-1296-5p | prostate cancer | MCM2 | "Here we examined the role of MCM2 in prostate canc ......" | 20332239 |
| hsa-miR-1296-5p | prostate cancer | PRDX2 | "Here we examined the role of MCM2 in prostate canc ......" | 20332239 |
Expression profile in cancer corhorts:
Putative target regulations
| miRNA | Gene | Cancer | Interaction | Correlation beta |
|---|---|---|---|---|
hsa-miR-1296-5p | PRKAR1A | 9 cancers: BLCA; COAD; ESCA; HNSC; LUAD; LUSC; PRAD; STAD; UCEC | miRNAWalker2 validate | TCGA BLCA -0.083; TCGA COAD -0.09; TCGA ESCA -0.082; TCGA HNSC -0.064; TCGA LUAD -0.05; TCGA LUSC -0.137; TCGA PRAD -0.121; TCGA STAD -0.101; TCGA UCEC -0.132 |
hsa-miR-1296-5p | PDZK1IP1 | 17 cancers: BLCA; BRCA; CESC; ESCA; HNSC; KIRC; KIRP; LGG; LIHC; LUAD; LUSC; OV; PAAD; PRAD; SARC; THCA; UCEC | MirTarget | TCGA BLCA -0.515; TCGA BRCA -0.199; TCGA CESC -0.589; TCGA ESCA -0.567; TCGA HNSC -0.511; TCGA KIRC -0.218; TCGA KIRP -0.32; TCGA LGG -0.246; TCGA LIHC -0.517; TCGA LUAD -0.25; TCGA LUSC -0.5; TCGA OV -0.343; TCGA PAAD -0.548; TCGA PRAD -0.3; TCGA SARC -0.685; TCGA THCA -0.907; TCGA UCEC -0.733 |
hsa-miR-1296-5p | MEF2C | 9 cancers: BLCA; COAD; ESCA; KIRC; LUSC; PRAD; SARC; STAD; UCEC | MirTarget | TCGA BLCA -0.299; TCGA COAD -0.315; TCGA ESCA -0.246; TCGA KIRC -0.113; TCGA LUSC -0.454; TCGA PRAD -0.164; TCGA SARC -0.145; TCGA STAD -0.206; TCGA UCEC -0.332 |
hsa-miR-1296-5p | CCDC50 | 11 cancers: BLCA; CESC; COAD; HNSC; KIRC; KIRP; LUSC; PAAD; SARC; STAD; UCEC | MirTarget | TCGA BLCA -0.111; TCGA CESC -0.073; TCGA COAD -0.059; TCGA HNSC -0.072; TCGA KIRC -0.085; TCGA KIRP -0.128; TCGA LUSC -0.173; TCGA PAAD -0.08; TCGA SARC -0.088; TCGA STAD -0.127; TCGA UCEC -0.072 |
hsa-miR-1296-5p | ZNFX1 | 13 cancers: BLCA; CESC; COAD; ESCA; HNSC; LGG; LIHC; LUSC; PAAD; PRAD; SARC; THCA; UCEC | MirTarget | TCGA BLCA -0.21; TCGA CESC -0.169; TCGA COAD -0.105; TCGA ESCA -0.128; TCGA HNSC -0.294; TCGA LGG -0.123; TCGA LIHC -0.179; TCGA LUSC -0.212; TCGA PAAD -0.135; TCGA PRAD -0.09; TCGA SARC -0.124; TCGA THCA -0.086; TCGA UCEC -0.139 |
hsa-miR-1296-5p | CXCL16 | 15 cancers: BLCA; CESC; COAD; ESCA; HNSC; KIRC; KIRP; LGG; LIHC; LUAD; LUSC; OV; PRAD; THCA; UCEC | MirTarget | TCGA BLCA -0.214; TCGA CESC -0.239; TCGA COAD -0.125; TCGA ESCA -0.187; TCGA HNSC -0.152; TCGA KIRC -0.219; TCGA KIRP -0.271; TCGA LGG -0.218; TCGA LIHC -0.126; TCGA LUAD -0.072; TCGA LUSC -0.347; TCGA OV -0.11; TCGA PRAD -0.063; TCGA THCA -0.265; TCGA UCEC -0.208 |
hsa-miR-1296-5p | KATNAL1 | 11 cancers: BLCA; CESC; COAD; HNSC; KIRP; LUSC; PRAD; SARC; THCA; STAD; UCEC | MirTarget | TCGA BLCA -0.309; TCGA CESC -0.084; TCGA COAD -0.148; TCGA HNSC -0.1; TCGA KIRP -0.091; TCGA LUSC -0.134; TCGA PRAD -0.196; TCGA SARC -0.065; TCGA THCA -0.061; TCGA STAD -0.168; TCGA UCEC -0.122 |
hsa-miR-1296-5p | ZNF521 | 9 cancers: BLCA; COAD; ESCA; LGG; LUSC; PAAD; PRAD; STAD; UCEC | MirTarget | TCGA BLCA -0.307; TCGA COAD -0.383; TCGA ESCA -0.168; TCGA LGG -0.086; TCGA LUSC -0.438; TCGA PAAD -0.232; TCGA PRAD -0.243; TCGA STAD -0.131; TCGA UCEC -0.238 |
hsa-miR-1296-5p | ECM2 | 9 cancers: BLCA; COAD; ESCA; LGG; LIHC; LUSC; PRAD; STAD; UCEC | MirTarget | TCGA BLCA -0.352; TCGA COAD -0.44; TCGA ESCA -0.181; TCGA LGG -0.387; TCGA LIHC -0.138; TCGA LUSC -0.578; TCGA PRAD -0.188; TCGA STAD -0.135; TCGA UCEC -0.253 |
hsa-miR-1296-5p | CYP4V2 | 13 cancers: BLCA; BRCA; CESC; ESCA; HNSC; KIRP; LGG; LUAD; LUSC; OV; SARC; STAD; UCEC | MirTarget | TCGA BLCA -0.167; TCGA BRCA -0.054; TCGA CESC -0.117; TCGA ESCA -0.264; TCGA HNSC -0.2; TCGA KIRP -0.154; TCGA LGG -0.116; TCGA LUAD -0.117; TCGA LUSC -0.352; TCGA OV -0.12; TCGA SARC -0.245; TCGA STAD -0.128; TCGA UCEC -0.166 |
hsa-miR-1296-5p | MTUS1 | 11 cancers: BRCA; CESC; ESCA; LIHC; LUAD; LUSC; PAAD; PRAD; SARC; STAD; UCEC | miRNAWalker2 validate | TCGA BRCA -0.069; TCGA CESC -0.113; TCGA ESCA -0.229; TCGA LIHC -0.134; TCGA LUAD -0.207; TCGA LUSC -0.083; TCGA PAAD -0.132; TCGA PRAD -0.172; TCGA SARC -0.127; TCGA STAD -0.171; TCGA UCEC -0.089 |
hsa-miR-1296-5p | BCL2L15 | 9 cancers: BRCA; CESC; ESCA; LIHC; LUAD; LUSC; PAAD; PRAD; UCEC | MirTarget | TCGA BRCA -0.086; TCGA CESC -0.375; TCGA ESCA -0.832; TCGA LIHC -0.192; TCGA LUAD -0.374; TCGA LUSC -0.378; TCGA PAAD -0.556; TCGA PRAD -0.239; TCGA UCEC -0.415 |
hsa-miR-1296-5p | UFM1 | 9 cancers: CESC; ESCA; KIRC; KIRP; LUAD; LUSC; OV; PRAD; UCEC | MirTarget | TCGA CESC -0.091; TCGA ESCA -0.144; TCGA KIRC -0.105; TCGA KIRP -0.053; TCGA LUAD -0.055; TCGA LUSC -0.11; TCGA OV -0.083; TCGA PRAD -0.072; TCGA UCEC -0.077 |
Enriched cancer pathways of putative targets