microRNA information: hsa-miR-130a-5p

SectionIDlink
Mature name: hsa-miR-130a-5pmiRbase
Accession: MIMAT0004593miRbase
Precursor name: hsa-mir-130a miRbase
Precursor accession: MI0000448miRbase
Symbol: MIR130AHGNC
RefSeq ID: NR_029673GenBank
Sequence: UUCACAUUGUGCUACUGUCUGC



Reported expression in cancers: hsa-miR-130a-5p

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-130a-5p

bladder cancerupregulation"We focused on the miR-130 family miR-130b miR-301a ......"26837847
hsa-miR-130a-5p

breast cancerdownregulation"MiR-130a has been demonstrated to play important r ......"25755726
hsa-miR-130a-5p

esophageal cancerderegulation"The expression profiles of miRNAs in paired EC and ......"23761828Microarray; qPCR
hsa-miR-130a-5p

gastric cancerupregulation"The high expression of miR-20a miR-25 miR-93 miR-1 ......"22996433
hsa-miR-130a-5p

head and neck cancerderegulation"Real-time polymerase chain reaction PCR analysis c ......"21560177qPCR
hsa-miR-130a-5p

liver cancerdownregulation"MicroRNA 130a is down regulated in hepatocellular ......"25218269qPCR
hsa-miR-130a-5p

lung cancerderegulation"Microarray studies revealed alterations in the exp ......"19748927Microarray; Reverse transcription PCR
hsa-miR-130a-5p

lung squamous cell cancerdownregulation"miR 130a regulates macrophage polarization and is ......"26398698qPCR
hsa-miR-130a-5p

melanomadownregulation"Among the miRNAs that were commonly and significan ......"27149382
hsa-miR-130a-5p

prostate cancerdownregulation"MiR 130a miR 203 and miR 205 jointly repress key o ......"22391564
hsa-miR-130a-5p

prostate cancerdownregulation"Microarray analysis of mRNA expression was also co ......"26074357Microarray
hsa-miR-130a-5p

thyroid cancerderegulation"Deregulated miRNAs were confirmed by quantitative ......"24127332qPCR; in situ hybridization



Reported cancer pathway affected by hsa-miR-130a-5p

miRNAcancerpathwayreportingPUBMEDfunctional study
hsa-miR-130a-5p

chronic myeloid leukemiaApoptosis pathway"Functional studies of miR 130a on the inhibitory p ......"26494558Western blot; Luciferase
hsa-miR-130a-5p

gastric cancerApoptosis pathway"Targeting of RUNX3 by miR 130a and miR 495 coopera ......"26375442Luciferase
hsa-miR-130a-5p

lung squamous cell cancerApoptosis pathway"MiR 130a overcomes gefitinib resistance by targeti ......"24606471
hsa-miR-130a-5p

ovarian cancerApoptosis pathway"Downregulation of miR 130a contributes to cisplati ......"24145606Flow cytometry; MTT assay
hsa-miR-130a-5p

ovarian cancerPI3K/Akt signaling pathway; Apoptosis pathway"Expression of MiR 130a in Serum Samples of Patient ......"27062783
hsa-miR-130a-5p

sarcomaEpithelial mesenchymal transition pathway"MicroRNA 130a promotes the metastasis and epitheli ......"27035216



Reported cancer prognosis affected by hsa-miR-130a-5p

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-130a-5p

B cell lymphomadrug resistance; progression; recurrence"Circulating microRNA 125b and microRNA 130a expres ......"26870228
hsa-miR-130a-5p

bladder cancermalignant trasformation"We screened 723 miRNAs by microarray and selected ......"23945108
hsa-miR-130a-5p

bladder cancercell migration; malignant trasformation; progression"The miR 130 family promotes cell migration and inv ......"26837847
hsa-miR-130a-5p

breast cancerdrug resistance"The drug resistance of MCF-7/ADR cells was evaluat ......"18971180Flow cytometry; MTT assay
hsa-miR-130a-5p

breast cancermetastasis; progression"Aberrant plasma levels of circulating miR 16 miR 1 ......"26033453
hsa-miR-130a-5p

breast cancerworse prognosis; drug resistance"The aim of this study was to investigate the role ......"27746365
hsa-miR-130a-5p

cervical and endocervical cancerpoor survival"Prognostic significance of low DICER expression re ......"24787017Luciferase
hsa-miR-130a-5p

chronic myeloid leukemiadrug resistance; poor survival; worse prognosis"Functional studies of miR 130a on the inhibitory p ......"26494558Western blot; Luciferase
hsa-miR-130a-5p

gastric cancermetastasis; poor survival"The high expression of miR-20a miR-25 miR-93 miR-1 ......"22996433
hsa-miR-130a-5p

gastric cancertumorigenesis; worse prognosis"miR 130a acts as a potential diagnostic biomarker ......"26134263Luciferase; Transwell assay
hsa-miR-130a-5p

gastric cancerprogression"Targeting of RUNX3 by miR 130a and miR 495 coopera ......"26375442Luciferase
hsa-miR-130a-5p

glioblastomapoor survival; recurrence"Moreover miR-326 miR-130a miR-155 miR-210 and 4 mi ......"23302469
hsa-miR-130a-5p

glioblastomadrug resistance"miR 130a can predict response to temozolomide in p ......"25890369
hsa-miR-130a-5p

liver cancerworse prognosis; staging; metastasis; tumor size; poor survival"MicroRNA 130a is down regulated in hepatocellular ......"25218269
hsa-miR-130a-5p

liver cancerprogression"This study investigated the potential of serum mic ......"26352740
hsa-miR-130a-5p

lung squamous cell cancerdrug resistance"MiR 130a overcomes gefitinib resistance by targeti ......"24606471
hsa-miR-130a-5p

lung squamous cell cancerworse prognosis; drug resistance; staging; metastasis"miR 130a regulates macrophage polarization and is ......"26398698Western blot; Luciferase
hsa-miR-130a-5p

ovarian cancerdrug resistance"High-throughput analysis of the miRNA profile in a ......"18823650
hsa-miR-130a-5p

ovarian cancerdrug resistance"Furthermore we discuss several other microRNAs tha ......"20083225
hsa-miR-130a-5p

ovarian cancerdrug resistance"Expression of miR 130a in cisplatin resistant cell ......"22455133MTT assay
hsa-miR-130a-5p

ovarian cancerdrug resistance"Altered microRNA expression in cisplatin resistant ......"22614869Western blot; MTT assay
hsa-miR-130a-5p

ovarian cancerdrug resistance"Downregulation of miR 130a contributes to cisplati ......"24145606Flow cytometry; MTT assay
hsa-miR-130a-5p

ovarian cancerdrug resistance"Regulatory effects and associated mechanisms of mi ......"24490491MTT assay; Western blot
hsa-miR-130a-5p

ovarian cancerdrug resistance"MiR 130a and MiR 374a Function as Novel Regulators ......"26043084Western blot
hsa-miR-130a-5p

ovarian cancerdrug resistance"NRP1 is targeted by miR 130a and miR 130b and is a ......"26573160
hsa-miR-130a-5p

ovarian cancerdrug resistance; metastasis"Expression of MiR 130a in Serum Samples of Patient ......"27062783
hsa-miR-130a-5p

prostate cancerdrug resistance"miR 130a activates apoptotic signaling through act ......"26074357Luciferase
hsa-miR-130a-5p

sarcomametastasis; worse prognosis"MicroRNA 130a promotes the metastasis and epitheli ......"27035216



Reported gene related to hsa-miR-130a-5p

miRNAcancergenereportingPUBMED
hsa-miR-130a-5p

bladder cancerPTEN"The miR 130 family promotes cell migration and inv ......"26837847
hsa-miR-130a-5p

cervical and endocervical cancerPTEN"In addition by targeting PTEN 3' untranslated regi ......"27040383
hsa-miR-130a-5p

ovarian cancerPTEN"Down-regulated miR-130a did not affect cell prolif ......"24490491
hsa-miR-130a-5p

ovarian cancerPTEN"Platinum-resistant patients had significantly high ......"27062783
hsa-miR-130a-5p

ovarian cancerPTEN"We found that miR-130a was upregulated in SKOV3/CI ......"22614869
hsa-miR-130a-5p

ovarian cancerPTEN"This role of miR-130a may be achieved by regulatin ......"26043084
hsa-miR-130a-5p

sarcomaPTEN"MicroRNA 130a promotes the metastasis and epitheli ......"27035216
hsa-miR-130a-5p

ovarian cancerABCB1"Over-expressions of miR-130a had no effect on cell ......"24490491
hsa-miR-130a-5p

ovarian cancerABCB1"Moreover downregulation of miR-130a could inhibit ......"22614869
hsa-miR-130a-5p

gastric cancerRUNX3"miR 130a acts as a potential diagnostic biomarker ......"26134263
hsa-miR-130a-5p

gastric cancerRUNX3"Targeting of RUNX3 by miR 130a and miR 495 coopera ......"26375442
hsa-miR-130a-5p

ovarian cancerABCB6"Moreover downregulation of miR-130a could inhibit ......"22614869
hsa-miR-130a-5p

cervical and endocervical cancerAKT1"In addition by targeting PTEN 3' untranslated regi ......"27040383
hsa-miR-130a-5p

glioblastomaAPEX1"GSEA and GO analysis indicated that lower miR-130a ......"25890369
hsa-miR-130a-5p

ovarian cancerBCL2"Platinum-resistant patients had significantly high ......"27062783
hsa-miR-130a-5p

gastric cancerBCL2L11"Combination of miR-130a and miR-495 significantly ......"26375442
hsa-miR-130a-5p

prostate cancerCASP8"miR 130a activates apoptotic signaling through act ......"26074357
hsa-miR-130a-5p

ovarian cancerCSF1"Finally downstream target validation was proven fo ......"18823650
hsa-miR-130a-5p

B cell lymphomaDDIT3"Circulating microRNA 125b and microRNA 130a expres ......"26870228
hsa-miR-130a-5p

cervical and endocervical cancerDICER1"Prognostic significance of low DICER expression re ......"24787017
hsa-miR-130a-5p

glioblastomaIGKV1D-35"miR 130a can predict response to temozolomide in p ......"25890369
hsa-miR-130a-5p

glioblastomaMGMT"miR 130a can predict response to temozolomide in p ......"25890369
hsa-miR-130a-5p

cervical and endocervical cancerNFASC"NF κB modulated miR 130a targets TNF α in cervic ......"24885472
hsa-miR-130a-5p

ovarian cancerNOL3"MTT assay and flow cytometry FCM results showed th ......"24145606
hsa-miR-130a-5p

ovarian cancerNRP1"NRP1 is targeted by miR 130a and miR 130b and is a ......"26573160
hsa-miR-130a-5p

bladder cancerPTK2"The miR 130 family promotes cell migration and inv ......"26837847
hsa-miR-130a-5p

breast cancerRAB5A"MicroRNA 130a inhibits cell proliferation invasion ......"25755726
hsa-miR-130a-5p

prostate cancerSLAIN1"Based on mRNA microarray analysis and luciferase r ......"26074357
hsa-miR-130a-5p

ovarian cancerTECRL"Altered microRNA expression in cisplatin resistant ......"22614869
hsa-miR-130a-5p

cervical and endocervical cancerTNF"NF κB modulated miR 130a targets TNF α in cervic ......"24885472
hsa-miR-130a-5p

chronic myeloid leukemiaTP53"We in this study aimed to investigate the function ......"26494558
hsa-miR-130a-5p

ovarian cancerXIAP"Downregulation of miR 130a contributes to cisplati ......"24145606



Expression profile in cancer corhorts: