microRNA information: hsa-miR-137

SectionIDlink
Mature name: hsa-miR-137miRbase
Accession: MIMAT0000429miRbase
Precursor name: hsa-mir-137 miRbase
Precursor accession: MI0000454miRbase
Symbol: MIR137HGNC
RefSeq ID: NR_029679GenBank
Sequence: UUAUUGCUUAAGAAUACGCGUAG



Reported expression in cancers: hsa-miR-137

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-137

bladder cancerupregulation"Previous studies have shown that miR-137 is dysreg ......"25330156
hsa-miR-137

breast cancerdownregulation"Several miRNAs have been reported to be involved i ......"25955714qPCR
hsa-miR-137

colon cancerupregulation"MicroRNA expression was analyzed with Agilent micr ......"19659786Microarray; qPCR
hsa-miR-137

colon cancerdownregulation"Among the miRNAs demonstrating the largest fold up ......"21694772
hsa-miR-137

colon cancerderegulation"Interestingly miRNA-137 miR-137 expression was dow ......"26747706
hsa-miR-137

colorectal cancerderegulation"Real time-polymerase chain reaction was used to an ......"26867319qPCR
hsa-miR-137

gastric cancerdownregulation"Some recent studies show that DNA methylation cont ......"21221794qPCR
hsa-miR-137

gastric cancerdownregulation"Clinical Significance of MiR 137 Expression in Pat ......"26545111qPCR
hsa-miR-137

gastric cancerdownregulation"Aberrant expression of miR-137 has been reported i ......"27468717qPCR
hsa-miR-137

glioblastomadownregulation"Here we study the expression and function of miR-1 ......"23714687
hsa-miR-137

glioblastomadownregulation"Here we showed that miR-137 is downregulated in gl ......"25939439
hsa-miR-137

liver cancerdownregulation"Here we show that microRNA miR-137 is significantl ......"24970808
hsa-miR-137

lung cancerdownregulation"Silencing of miR 137 by aberrant promoter hypermet ......"26101014qPCR; RNA-Seq
hsa-miR-137

lung cancerdownregulation"MicroRNA 137 inhibits tumor growth and sensitizes ......"26989074
hsa-miR-137

lung squamous cell cancerdownregulation"Currently a large number of miRNAs have been repor ......"24243432
hsa-miR-137

lung squamous cell cancerdownregulation"More importantly the decreased expression of miR-1 ......"25498886
hsa-miR-137

lung squamous cell cancerdownregulation"MicroRNA-137 miR-137 was reported to be dysregulat ......"26617798qPCR
hsa-miR-137

ovarian cancerdownregulation"Several miRNAs have been reported to be involved i ......"25955305qPCR
hsa-miR-137

thyroid cancerdownregulation"microRNA-137 expression is downregulated in severa ......"26695142
hsa-miR-137

thyroid cancerdownregulation"microRNA-137 miR-137 has been reported as a tumor ......"26847706qPCR



Reported cancer pathway affected by hsa-miR-137

miRNAcancerpathwayreportingPUBMEDfunctional study
hsa-miR-137

breast cancerApoptosis pathway"Several miRNAs have been reported to be involved i ......"25955714
hsa-miR-137

colorectal cancercell cycle pathway"miR 137 targets Cdc42 expression induces cell cycl ......"20473940Luciferase
hsa-miR-137

gastric cancercell cycle pathway; Apoptosis pathway"miR 137 is frequently down regulated in gastric ca ......"21221794
hsa-miR-137

gastric cancercell cycle pathway"MicroRNA library based functional screening identi ......"25342326Flow cytometry; MTT assay; Luciferase
hsa-miR-137

gastric cancerApoptosis pathway"MicroRNA 137 Contributes to Dampened Tumorigenesis ......"26102366Western blot; Luciferase
hsa-miR-137

gastric cancerHippo signaling pathway"Cullin 4A CUL4A a direct target of miR 9 and miR 1 ......"26840256
hsa-miR-137

gastric cancercell cycle pathway"miR 137 plays tumor suppressor roles in gastric ca ......"27468717Transwell assay; Western blot; Luciferase
hsa-miR-137

glioblastomacell cycle pathway"miR 124 and miR 137 inhibit proliferation of gliob ......"18577219
hsa-miR-137

glioblastomacell cycle pathway; Apoptosis pathway"Direct transfection of miR 137 mimics is more effe ......"26187071
hsa-miR-137

head and neck cancercell cycle pathway"MicroRNA 137 promoter methylation in oral rinses f ......"20197299
hsa-miR-137

head and neck cancercell cycle pathway"MicroRNA 137 promoter methylation is associated wi ......"21425146
hsa-miR-137

lung cancercell cycle pathway"miR 137 inhibits the proliferation of lung cancer ......"23178712
hsa-miR-137

lung cancercell cycle pathway"MicroRNA 137 inhibits tumor growth and sensitizes ......"26989074
hsa-miR-137

lung cancerApoptosis pathway"Oncogenic miR 137 contributes to cisplatin resista ......"27429846Luciferase
hsa-miR-137

lung squamous cell cancerApoptosis pathway"miR 137 impairs the proliferative and migratory ca ......"24243432
hsa-miR-137

melanomacell cycle pathway"Epigenetics microRNAs and carcinogenesis: function ......"21051724Flow cytometry; Cell Proliferation Assay; Luciferase; Western blot
hsa-miR-137

melanomaApoptosis pathway; Epithelial mesenchymal transition pathway"MicroRNA 137 targets carboxyl terminal binding pro ......"21278922Luciferase
hsa-miR-137

melanomaApoptosis pathway"miR 137 inhibits the invasion of melanoma cells th ......"23151846
hsa-miR-137

ovarian cancerApoptosis pathway"MicroRNA 137 suppresses tumor growth in epithelial ......"25955305



Reported cancer prognosis affected by hsa-miR-137

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-137

bladder cancerstaging"MicroRNA 137 upregulation increases bladder cancer ......"25330156
hsa-miR-137

breast cancerprogression; poor survival"Several miRNAs have been reported to be involved i ......"25955714
hsa-miR-137

breast cancertumorigenesis"In the present study we examined the role played b ......"26621457
hsa-miR-137

colorectal cancerworse prognosis"miR 124 miR 137 and miR 340 regulate colorectal ca ......"22895557
hsa-miR-137

colorectal cancermetastasis"MicroRNA 137 an HMGA1 target suppresses colorectal ......"23201162Luciferase
hsa-miR-137

colorectal cancermetastasis; progression; worse prognosis"Overexpression of paxillin induced by miR 137 supp ......"23275153Luciferase
hsa-miR-137

colorectal cancerprogression"Tumor suppressive microRNA 137 negatively regulate ......"25940441Luciferase; Colony formation
hsa-miR-137

gastric cancertumorigenesis"miR 137 is frequently down regulated in gastric ca ......"21221794
hsa-miR-137

gastric cancerprogression; worse prognosis"MicroRNA library based functional screening identi ......"25342326Flow cytometry; MTT assay; Luciferase
hsa-miR-137

gastric cancertumorigenesis; metastasis"MicroRNA 137 Contributes to Dampened Tumorigenesis ......"26102366Western blot; Luciferase
hsa-miR-137

gastric cancerprogression; worse prognosis; staging; differentiation; poor survival"Clinical Significance of MiR 137 Expression in Pat ......"26545111
hsa-miR-137

gastric cancercell migration; poor survival; staging"miR 137 plays tumor suppressor roles in gastric ca ......"27468717Transwell assay; Western blot; Luciferase
hsa-miR-137

glioblastomadifferentiation"miR 124 and miR 137 inhibit proliferation of gliob ......"18577219
hsa-miR-137

glioblastomadifferentiation"MicroRNA 137 is downregulated in glioblastoma and ......"23714687Luciferase
hsa-miR-137

glioblastomamalignant trasformation; differentiation"Genomic analyses reveal broad impact of miR 137 on ......"24465609
hsa-miR-137

glioblastomaprogression"Direct transfection of miR 137 mimics is more effe ......"26187071
hsa-miR-137

head and neck cancerpoor survival; progression; staging; tumor size"MicroRNA 137 promoter methylation is associated wi ......"21425146
hsa-miR-137

liver cancermetastasis; poor survival; progression; worse prognosis"FoxD3 regulated microRNA 137 suppresses tumour gro ......"24970808
hsa-miR-137

liver cancermetastasis"Inhibition of cell proliferation and metastasis of ......"26352279Western blot; Luciferase
hsa-miR-137

liver cancercell migration"HEY2 a target of miR 137 indicates poor outcomes a ......"27191260Colony formation
hsa-miR-137

liver cancerpoor survival"Prognostic relevance of miR 137 in patients with h ......"27473646
hsa-miR-137

lung cancerstaging; metastasis; progression"In this work the methylation of six miRNA genes mi ......"24450160
hsa-miR-137

lung cancerdrug resistance"To address this issue we inserted microRNA respons ......"25132116
hsa-miR-137

lung cancerpoor survival"MicroRNA 137 inhibits tumor growth and sensitizes ......"26989074
hsa-miR-137

lung cancerdrug resistance; worse prognosis; poor survival"Oncogenic miR 137 contributes to cisplatin resista ......"27429846Luciferase
hsa-miR-137

lung squamous cell cancerprogression; cell migration"miR 137 impairs the proliferative and migratory ca ......"24243432
hsa-miR-137

lung squamous cell cancerstaging; metastasis; worse prognosis; progression"microRNA 137 functions as a tumor suppressor in hu ......"25498886Luciferase
hsa-miR-137

lung squamous cell cancercell migration; progression"MicroRNA 137 inhibits cell migration and invasion ......"26617798Luciferase
hsa-miR-137

melanomatumorigenesis"Epigenetics microRNAs and carcinogenesis: function ......"21051724Flow cytometry; Cell Proliferation Assay; Luciferase; Western blot
hsa-miR-137

melanomamalignant trasformation; staging; poor survival; cell migration"miR 137 inhibits the invasion of melanoma cells th ......"23151846
hsa-miR-137

melanomadrug resistance"To improve uveal melanoma specificity of adenoviru ......"24001901Luciferase
hsa-miR-137

ovarian cancerprogression; poor survival"MicroRNA 137 suppresses tumor growth in epithelial ......"25955305
hsa-miR-137

ovarian cancerpoor survival"MiR 137 and miR 34a directly target Snail and inhi ......"27596137Western blot; Luciferase
hsa-miR-137

pancreatic cancerpoor survival; cell migration; tumor size"microRNA 137 modulates pancreatic cancer cells tum ......"25550779
hsa-miR-137

pancreatic cancerdrug resistance"miR 137 Modulates a Tumor Suppressor Network Induc ......"26904954
hsa-miR-137

thyroid cancermalignant trasformation; progression"microRNA 137 is downregulated in thyroid cancer an ......"26695142Colony formation; Luciferase
hsa-miR-137

thyroid cancerstaging; metastasis"MiR 137 acts as a tumor suppressor in papillary th ......"26847706Colony formation; Luciferase; Western blot



Reported gene related to hsa-miR-137

miRNAcancergenereportingPUBMED
hsa-miR-137

colorectal cancerCDC42"miR 137 targets Cdc42 expression induces cell cycl ......"20473940
hsa-miR-137

gastric cancerCDC42"miR 137 is frequently down regulated in gastric ca ......"21221794
hsa-miR-137

liver cancerCDC42"Inhibition of cell proliferation and metastasis of ......"26352279
hsa-miR-137

lung cancerCDC42"miR 137 inhibits the proliferation of lung cancer ......"23178712
hsa-miR-137

gastric cancerCDK6"Bioinformatics prediction and luciferase reporter ......"25342326
hsa-miR-137

glioblastomaCDK6"Transfection of microRNA-124 or microRNA-137 also ......"18577219
hsa-miR-137

lung cancerCDK6"miR 137 inhibits the proliferation of lung cancer ......"23178712
hsa-miR-137

melanomaCDK6"The results showed that miR-137 can act as a tumor ......"21051724
hsa-miR-137

melanomaMITF"In addition we confirm the previously reported eff ......"20644734
hsa-miR-137

melanomaMITF"In these studies we have identified microRNA-137 m ......"18316599
hsa-miR-137

melanomaMITF"Overexpression of miR-137 downregulated MITF a tra ......"21051724
hsa-miR-137

gastric cancerAKT2"MicroRNA 137 Contributes to Dampened Tumorigenesis ......"26102366
hsa-miR-137

liver cancerAKT2"FoxD3 regulated microRNA 137 suppresses tumour gro ......"24970808
hsa-miR-137

breast cancerCTBP1"miR 137 suppresses the invasion and procedure of E ......"26337822
hsa-miR-137

melanomaCTBP1"In the present study we identified miR-137 as a po ......"21278922
hsa-miR-137

lung cancerEGFR"Moreover the endogenous CASP3 can be modulated by ......"27429846
hsa-miR-137

thyroid cancerEGFR"microRNA 137 is downregulated in thyroid cancer an ......"26695142
hsa-miR-137

glioblastomaGSC"Furthermore combining miR-137 and antimiR-10b syne ......"27448441
hsa-miR-137

glioblastomaGSC"miR-137 inhibits GSC self-renewal and promotes the ......"23714687
hsa-miR-137

colorectal cancerPXN"Overexpression of paxillin induced by miR 137 supp ......"23275153
hsa-miR-137

lung squamous cell cancerPXN"miR 137 impairs the proliferative and migratory ca ......"24243432
hsa-miR-137

melanomaBCL2"Finally miR-137 induced apoptosis in melanoma cell ......"23151846
hsa-miR-137

lung squamous cell cancerBMP7"MicroRNA 137 inhibits cell migration and invasion ......"26617798
hsa-miR-137

lung cancerCASP3"Oncogenic miR 137 contributes to cisplatin resista ......"27429846
hsa-miR-137

gastric cancerCUL4A"Interestingly CUL4A expression was inhibited by th ......"26840256
hsa-miR-137

thyroid cancerCXCL12"MiR 137 acts as a tumor suppressor in papillary th ......"26847706
hsa-miR-137

glioblastomaCXCR4"miR-137 inhibits GSC self-renewal and promotes the ......"23714687
hsa-miR-137

colon cancerDCLK1"miR 137 Regulates the Tumorigenicity of Colon Canc ......"26747706
hsa-miR-137

glioblastomaDCLRE1C"In addition ectopic expression of miR-137 inhibite ......"25939439
hsa-miR-137

thyroid cancerEGF"With prediction software and luciferase reporter a ......"26695142
hsa-miR-137

glioblastomaEZH2"MiR 137 inhibits proliferation and angiogenesis of ......"25939439
hsa-miR-137

colorectal cancerFMNL2"MicroRNA 137 an HMGA1 target suppresses colorectal ......"23201162
hsa-miR-137

liver cancerFOXO1"Together these results indicate that the rs1759223 ......"25739100
hsa-miR-137

sarcomaFXYD6"MicroRNA 137 is downregulated in human osteosarcom ......"26302771
hsa-miR-137

lung cancerHDAC9"Lung cancer cell lines were treated with either a ......"26101014
hsa-miR-137

liver cancerHEY2"HEY2 a target of miR 137 indicates poor outcomes a ......"27191260
hsa-miR-137

colorectal cancerHMGA1"MicroRNA 137 an HMGA1 target suppresses colorectal ......"23201162
hsa-miR-137

pancreatic cancerKDM4A"Restoring the KDM4A expression contributed to bypa ......"26904954
hsa-miR-137

breast cancerKDM5B"We further identified KDM5B a histone demethylase ......"26621457
hsa-miR-137

gastric cancerKLF12"miR 137 plays tumor suppressor roles in gastric ca ......"27468717
hsa-miR-137

breast cancerMBD2"We further identified KDM5B a histone demethylase ......"26621457
hsa-miR-137

pancreatic cancerMIA"Lentivirual vector containing miR-137 mimic was us ......"25550779
hsa-miR-137

thyroid cancerMMP2"miR-137 mimics downregulated B-CPAP cell prolifera ......"26695142
hsa-miR-137

colorectal cancerMSI1"Tumor suppressive microRNA 137 negatively regulate ......"25940441
hsa-miR-137

ovarian cancerMTDH"miR 137 suppresses cell growth in ovarian cancer b ......"24144591
hsa-miR-137

gastric cancerMYO1C"miR 137 plays tumor suppressor roles in gastric ca ......"27468717
hsa-miR-137

glioblastomaPABPC1"To evaluate the potential of miR-137 in glioblasto ......"24465609
hsa-miR-137

melanomaPAK2"miR 137 inhibits proliferation of melanoma cells b ......"26186482
hsa-miR-137

bladder cancerPAQR3"MicroRNA 137 upregulation increases bladder cancer ......"25330156
hsa-miR-137

thyroid cancerPCNA"miR-137 mimics downregulated B-CPAP cell prolifera ......"26695142
hsa-miR-137

lung cancerPDIK1L"We further demonstrated that the tumor suppressive ......"26989074
hsa-miR-137

lung cancerPRDX2"Lung cancer cell lines were treated with either a ......"26101014
hsa-miR-137

glioblastomaPTGS2"miR 137 is frequently down regulated in glioblasto ......"22406049
hsa-miR-137

pancreatic cancerPTN"The molecular target of miR-137 pleiotropic growth ......"25550779
hsa-miR-137

lung squamous cell cancerSCLC1"MiR-137 expression was examined in parental and dr ......"24412084
hsa-miR-137

lung squamous cell cancerSLC22A18"microRNA 137 functions as a tumor suppressor in hu ......"25498886
hsa-miR-137

ovarian cancerSNAI1"MiR 137 and miR 34a directly target Snail and inhi ......"27596137
hsa-miR-137

glioblastomaVEGFA"Combination of miR-137 mimics transfection and DPN ......"26187071
hsa-miR-137

breast cancerWNT11"Furthermore transfection with miR-137 mimics suppr ......"22723937