microRNA information: hsa-miR-144-5p

SectionIDlink
Mature name: hsa-miR-144-5pmiRbase
Accession: MIMAT0004600miRbase
Precursor name: hsa-mir-144 miRbase
Precursor accession: MI0000460miRbase
Symbol: MIR144HGNC
RefSeq ID: NR_029685GenBank
Sequence: GGAUAUCAUCAUAUACUGUAAG



Reported expression in cancers: hsa-miR-144-5p

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-144-5p

bladder cancerdownregulation"Tumour suppressive microRNA 144 5p directly target ......"26057453RNA-Seq
hsa-miR-144-5p

breast cancerderegulation"Next-generation sequencing evaluated miR expressio ......"26124344RNA-Seq; Reverse transcription PCR
hsa-miR-144-5p

colorectal cancerdownregulation"Quantitative RT-PCR was used to evaluate the clini ......"22983984qPCR
hsa-miR-144-5p

esophageal cancerupregulation"By Agilent microarray six deregulated miRNAs from ......"23560033Microarray; qPCR
hsa-miR-144-5p

esophageal cancerupregulation"Potential diagnostic implications of miR 144 overe ......"27748283qPCR
hsa-miR-144-5p

gastric cancerdownregulation"MicroRNA 144 inhibits the metastasis of gastric ca ......"25927670
hsa-miR-144-5p

liver cancerderegulation"The aim of this study was to investigate the role ......"27536132
hsa-miR-144-5p

lung cancerdownregulation"Among them miR-144 was one of the most significant ......"26395400
hsa-miR-144-5p

melanomadownregulation"However the role of miR-144 in uveal melanoma meta ......"25961751
hsa-miR-144-5p

prostate cancerupregulation"In PC patients after cisplatin treatment low miR-1 ......"26566625
hsa-miR-144-5p

sarcomadownregulation"In the present study miR-144 was markedly downregu ......"25912304
hsa-miR-144-5p

thyroid cancerdownregulation"Most miRNAs were down-regulated and especially miR ......"22049245qPCR; Microarray
hsa-miR-144-5p

thyroid cancerdownregulation"In the present study we found that the expression ......"24968735



Reported cancer pathway affected by hsa-miR-144-5p

miRNAcancerpathwayreportingPUBMEDfunctional study
hsa-miR-144-5p

bladder cancerWnt signaling pathway"miR 144 downregulation increases bladder cancer ce ......"23815091
hsa-miR-144-5p

bladder cancercell cycle pathway"Tumour suppressive microRNA 144 5p directly target ......"26057453Luciferase
hsa-miR-144-5p

colorectal cancermTOR signaling pathway"Downregulation of miR 144 is associated with color ......"22983984
hsa-miR-144-5p

liver cancerApoptosis pathway"HepG2 cells transfected with versican 3'-UTR displ ......"23180826Colony formation
hsa-miR-144-5p

liver cancerApoptosis pathway"miR 144 suppresses the proliferation and metastasi ......"25073510
hsa-miR-144-5p

liver cancercell cycle pathway; Epithelial mesenchymal transition pathway"MiR 144 suppresses cell proliferation migration an ......"27536132
hsa-miR-144-5p

lung cancerApoptosis pathway"MiR 144 inhibits proliferation and induces apoptos ......"25660220Western blot; Flow cytometry; Luciferase; Colony formation
hsa-miR-144-5p

lung cancerEpithelial mesenchymal transition pathway"Down regulation of microRNA 144 in air pollution r ......"26395400
hsa-miR-144-5p

lung squamous cell cancerApoptosis pathway"Roles of Mir 144 ZFX pathway in growth regulation ......"24066116
hsa-miR-144-5p

sarcomaApoptosis pathway"MicroRNA 144 inhibits the proliferation apoptosis ......"25854173Western blot; MTT assay; Transwell assay; Flow cytometry



Reported cancer prognosis affected by hsa-miR-144-5p

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-144-5p

bladder cancerpoor survival"Tumour suppressive microRNA 144 5p directly target ......"26057453Luciferase
hsa-miR-144-5p

breast cancerdrug resistance; progression; tumorigenesis"MicroRNA 144 affects radiotherapy sensitivity by p ......"26252024Western blot
hsa-miR-144-5p

colorectal cancerprogression; metastasis; malignant trasformation; worse prognosis; recurrence; poor survival"Downregulation of miR 144 is associated with color ......"22983984
hsa-miR-144-5p

colorectal cancerstaging; drug resistance"To explore the potential molecular biomarkers pred ......"24460313
hsa-miR-144-5p

esophageal cancermalignant trasformation"Potential diagnostic implications of miR 144 overe ......"27748283
hsa-miR-144-5p

gastric cancerstaging; worse prognosis"Clinical significance of miR 144 ZFX axis in disse ......"22955854Western blot; Luciferase
hsa-miR-144-5p

gastric cancermetastasis; cell migration; progression"MicroRNA 144 inhibits the metastasis of gastric ca ......"25927670
hsa-miR-144-5p

gastric cancerpoor survival"Then we further investigated these GC specific miR ......"27173517
hsa-miR-144-5p

gastric cancermalignant trasformation"Forty cases of carcinoma tissue and para-carcinoma ......"27261864Western blot
hsa-miR-144-5p

kidney renal cell cancermetastasis"miR 144 3p serves as a tumor suppressor for renal ......"27717821
hsa-miR-144-5p

liver cancerpoor survival"HepG2 cells transfected with versican 3'-UTR displ ......"23180826Colony formation
hsa-miR-144-5p

liver cancermetastasis; progression; motility"miR 144 suppresses the proliferation and metastasi ......"25073510
hsa-miR-144-5p

liver cancermetastasis; drug resistance"MiR 144 suppresses cell proliferation migration an ......"27536132
hsa-miR-144-5p

lung squamous cell cancermalignant trasformation"Roles of Mir 144 ZFX pathway in growth regulation ......"24066116
hsa-miR-144-5p

lung squamous cell cancermetastasis"The differentially expressed microRNAs associated ......"25628919
hsa-miR-144-5p

lung squamous cell cancermetastasis"Regulation of activating protein 4 associated meta ......"26254097Luciferase
hsa-miR-144-5p

melanomametastasis"MiR 144 Inhibits Uveal Melanoma Cell Proliferation ......"25961751Luciferase
hsa-miR-144-5p

prostate cancerpoor survival"VEGF activated miR 144 regulates autophagic surviv ......"26566625Luciferase
hsa-miR-144-5p

sarcomadifferentiation"In order to investigate the involvement of miRNAs ......"23133552
hsa-miR-144-5p

sarcomametastasis; malignant trasformation"The downregulation of miR 144 is associated with t ......"25318625
hsa-miR-144-5p

sarcomametastasis; staging; tumor size"MicroRNA 144 inhibits the proliferation apoptosis ......"25854173Western blot; MTT assay; Transwell assay; Flow cytometry
hsa-miR-144-5p

sarcomametastasis; worse prognosis; progression"MicroRNA 144 suppresses osteosarcoma growth and me ......"25912304
hsa-miR-144-5p

thyroid cancertumorigenesis"Down regulation of miR 144 promotes thyroid cancer ......"24968735



Reported gene related to hsa-miR-144-5p

miRNAcancergenereportingPUBMED
hsa-miR-144-5p

gastric cancerMET"The results of qRT-PCR and western-blot proved tha ......"27261864
hsa-miR-144-5p

gastric cancerMET"The met proto-oncogene MET which is often amplifie ......"25927670
hsa-miR-144-5p

glioblastomaMET"miR 144 3p exerts anti tumor effects in glioblasto ......"26250785
hsa-miR-144-5p

melanomaMET"MiR 144 Inhibits Uveal Melanoma Cell Proliferation ......"25961751
hsa-miR-144-5p

lung cancerSLC2A1"Downregulating microRNA 144 mediates a metabolic s ......"27313692
hsa-miR-144-5p

ovarian cancerSLC2A1"MicroRNA 144 mediates metabolic shift in ovarian c ......"26662316
hsa-miR-144-5p

lung cancerZEB1"MiR-144 interacted with the oncogene Zeb1 at 2 sit ......"26395400
hsa-miR-144-5p

thyroid cancerZEB1"Down regulation of miR 144 promotes thyroid cancer ......"24968735
hsa-miR-144-5p

gastric cancerZFX"Clinical significance of miR 144 ZFX axis in disse ......"22955854
hsa-miR-144-5p

lung squamous cell cancerZFX"Roles of Mir 144 ZFX pathway in growth regulation ......"24066116
hsa-miR-144-5p

lung cancerAIR"Down regulation of microRNA 144 in air pollution r ......"26395400
hsa-miR-144-5p

B cell lymphomaBCL6"In the current study we screened the microRNA expr ......"26865454
hsa-miR-144-5p

prostate cancerBECN1"Bioinformatics analysis showed that miR-144 target ......"26566625
hsa-miR-144-5p

lung cancerC12ORF5"MiR 144 inhibits proliferation and induces apoptos ......"25660220
hsa-miR-144-5p

bladder cancerCCNE1"The patients with high CCNE1 or CCNE2 expression h ......"26057453
hsa-miR-144-5p

bladder cancerCCNE2"The patients with high CCNE1 or CCNE2 expression h ......"26057453
hsa-miR-144-5p

breast cancerCDH1"In addition the overexpression of miR-144 inhibite ......"26252024
hsa-miR-144-5p

sarcomaCOIL"MicroRNA 144 acts as a tumor suppressor by targeti ......"26081423
hsa-miR-144-5p

liver cancerE2F3"miR 144 suppresses the proliferation and metastasi ......"25073510
hsa-miR-144-5p

bladder cancerEZH2"miR 144 downregulation increases bladder cancer ce ......"23815091
hsa-miR-144-5p

sarcomaEZR"MiR-144 levels and Ezrin messenger RNA mRNA levels ......"25854173
hsa-miR-144-5p

glioblastomaGLI1"Thirteen miRNAs including miR-125b-1 were downregu ......"24688313
hsa-miR-144-5p

thyroid cancerKRT1"Moreover our results showed that restoration of mi ......"24968735
hsa-miR-144-5p

kidney renal cell cancerMAP3K8"miR 144 3p serves as a tumor suppressor for renal ......"27717821
hsa-miR-144-5p

colorectal cancerMTOR"Downregulation of miR 144 is associated with color ......"22983984
hsa-miR-144-5p

colorectal cancerNOTCH1"Nanoparticle based delivery of siDCAMKL 1 increase ......"21929751
hsa-miR-144-5p

gastric cancerNOVA2"Quantitative reverse-transcriptase RT-PCR analysis ......"22955854
hsa-miR-144-5p

breast cancerPTEN"miR-144 activated AKT by downregulation of PTEN in ......"26252024
hsa-miR-144-5p

esophageal cancerPURA"Bioinformatically predicted target PUR-aplha PURA ......"27748283
hsa-miR-144-5p

lung squamous cell cancerREPIN1"Here we showed that in the specimens from the NSCL ......"26254097
hsa-miR-144-5p

colorectal cancerRICTOR"Among many genes consisting of the mTOR pathway on ......"22983984
hsa-miR-144-5p

sarcomaROCK1"Furthermore we identified Rho-associated kinases 1 ......"25912304
hsa-miR-144-5p

sarcomaROCK2"Furthermore we identified Rho-associated kinases 1 ......"25912304
hsa-miR-144-5p

liver cancerSMAD4"MiR 144 suppresses cell proliferation migration an ......"27536132
hsa-miR-144-5p

breast cancerSNAI1"In addition the overexpression of miR-144 inhibite ......"26252024
hsa-miR-144-5p

sarcomaTAGLN"The downregulation of miR 144 is associated with t ......"25318625
hsa-miR-144-5p

liver cancerTCF3"E2F transcription factor 3 E2F3 was identified as ......"25073510
hsa-miR-144-5p

prostate cancerVEGFA"VEGF activated miR 144 regulates autophagic surviv ......"26566625
hsa-miR-144-5p

thyroid cancerZEB2"Down regulation of miR 144 promotes thyroid cancer ......"24968735



Expression profile in cancer corhorts:




Putative target regulations

miRNAGeneCancerInteractionCorrelation beta
hsa-miR-144-5p
NOX4
13 cancers: BLCA; BRCA; CESC; COAD; ESCA; HNSC; LIHC; LUAD; LUSC; PRAD; THCA; STAD; UCEC
MirTarget
TCGA BLCA -0.207; TCGA BRCA -0.07; TCGA CESC -0.076; TCGA COAD -0.281; TCGA ESCA -0.241; TCGA HNSC -0.173; TCGA LIHC -0.271; TCGA LUAD -0.204; TCGA LUSC -0.21; TCGA PRAD -0.192; TCGA THCA -0.408; TCGA STAD -0.366; TCGA UCEC -0.155
hsa-miR-144-5p
SFRP4
10 cancers: BLCA; CESC; COAD; ESCA; HNSC; LIHC; LUAD; PRAD; STAD; UCEC
MirTarget
TCGA BLCA -0.942; TCGA CESC -0.36; TCGA COAD -0.713; TCGA ESCA -0.943; TCGA HNSC -0.524; TCGA LIHC -0.352; TCGA LUAD -0.231; TCGA PRAD -0.188; TCGA STAD -0.968; TCGA UCEC -0.64
hsa-miR-144-5p
CDH11
10 cancers: BLCA; BRCA; COAD; ESCA; HNSC; LIHC; PRAD; THCA; STAD; UCEC
mirMAP
TCGA BLCA -0.322; TCGA BRCA -0.195; TCGA COAD -0.256; TCGA ESCA -0.176; TCGA HNSC -0.157; TCGA LIHC -0.195; TCGA PRAD -0.187; TCGA THCA -0.234; TCGA STAD -0.316; TCGA UCEC -0.22
hsa-miR-144-5p
LGI2
10 cancers: BLCA; COAD; ESCA; HNSC; KIRC; LIHC; LUAD; PRAD; STAD; UCEC
mirMAP
TCGA BLCA -0.207; TCGA COAD -0.266; TCGA ESCA -0.375; TCGA HNSC -0.156; TCGA KIRC -0.225; TCGA LIHC -0.262; TCGA LUAD -0.137; TCGA PRAD -0.075; TCGA STAD -0.285; TCGA UCEC -0.13
hsa-miR-144-5p
ANTXR1
10 cancers: BLCA; BRCA; COAD; ESCA; HNSC; LGG; LUAD; PRAD; STAD; UCEC
mirMAP
TCGA BLCA -0.213; TCGA BRCA -0.077; TCGA COAD -0.294; TCGA ESCA -0.193; TCGA HNSC -0.057; TCGA LGG -0.083; TCGA LUAD -0.062; TCGA PRAD -0.165; TCGA STAD -0.256; TCGA UCEC -0.141
hsa-miR-144-5p
SGCD
9 cancers: BLCA; CESC; COAD; ESCA; HNSC; LGG; SARC; STAD; UCEC
mirMAP
TCGA BLCA -0.483; TCGA CESC -0.16; TCGA COAD -0.382; TCGA ESCA -0.331; TCGA HNSC -0.164; TCGA LGG -0.059; TCGA SARC -0.186; TCGA STAD -0.313; TCGA UCEC -0.198
hsa-miR-144-5p
POU2F1
10 cancers: BRCA; CESC; KIRC; KIRP; LGG; LIHC; LUAD; PRAD; THCA; STAD
mirMAP
TCGA BRCA -0.072; TCGA CESC -0.08; TCGA KIRC -0.065; TCGA KIRP -0.1; TCGA LGG -0.065; TCGA LIHC -0.128; TCGA LUAD -0.064; TCGA PRAD -0.093; TCGA THCA -0.068; TCGA STAD -0.077





Enriched cancer pathways of putative targets