microRNA information: hsa-miR-33b-5p

SectionIDlink
Mature name: hsa-miR-33b-5pmiRbase
Accession: MIMAT0003301miRbase
Precursor name: hsa-mir-33b miRbase
Precursor accession: MI0003646miRbase
Symbol: MIR33BHGNC
RefSeq ID: NR_030361GenBank
Sequence: GUGCAUUGCUGUUGCAUUGC



Reported expression in cancers: hsa-miR-33b-5p

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-33b-5p

bladder cancerupregulation"Samples were analyzed with a miRNA array containin ......"22863868Microarray
hsa-miR-33b-5p

breast cancerdownregulation"Here we report the identification of miR-33b as a ......"25919570
hsa-miR-33b-5p

colorectal cancerdownregulation"MicroRNA 33b inhibits tumor cell growth and is ass ......"26329295qPCR
hsa-miR-33b-5p

gastric cancerdownregulation"DNA Methylation mediated down regulating of MicroR ......"26729612



Reported cancer pathway affected by hsa-miR-33b-5p

miRNAcancerpathwayreportingPUBMEDfunctional study
hsa-miR-33b-5p

colorectal cancercell cycle pathway"MicroRNA 33b inhibits tumor cell growth and is ass ......"26329295Flow cytometry; Colony formation; MTT assay; Western blot
hsa-miR-33b-5p

gastric cancerApoptosis pathway"Curcumin inhibits cell growth and induces cell apo ......"27456358Western blot; Luciferase
hsa-miR-33b-5p

lung cancerEpithelial mesenchymal transition pathway"MicroRNA 33b inhibits lung adenocarcinoma cell gro ......"26459797Luciferase



Reported cancer prognosis affected by hsa-miR-33b-5p

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-33b-5p

bladder cancerstaging"Samples were analyzed with a miRNA array containin ......"22863868
hsa-miR-33b-5p

breast cancermetastasis; progression"MicroRNA 33b Inhibits Breast Cancer Metastasis by ......"25919570
hsa-miR-33b-5p

colorectal cancerworse prognosis; progression; staging; tumor size"MicroRNA 33b inhibits tumor cell growth and is ass ......"26329295Flow cytometry; Colony formation; MTT assay; Western blot
hsa-miR-33b-5p

gastric cancerstaging; tumorigenesis"DNA Methylation mediated down regulating of MicroR ......"26729612
hsa-miR-33b-5p

gastric cancerstaging"Curcumin inhibits cell growth and induces cell apo ......"27456358Western blot; Luciferase
hsa-miR-33b-5p

liver cancermalignant trasformation"Using gene expression microarrays and high-through ......"26646011
hsa-miR-33b-5p

lung cancermetastasis"MicroRNA 33b inhibits lung adenocarcinoma cell gro ......"26459797Luciferase
hsa-miR-33b-5p

lung cancerpoor survival; drug resistance"DNA damage responsive miR 33b 3p promoted lung can ......"27559850
hsa-miR-33b-5p

melanomametastasis"MicroRNA 33b upregulated by EF24 a curcumin analog ......"25725129Luciferase
hsa-miR-33b-5p

melanomametastasis"Cordycepin 3' deoxyadenosine suppressed HMGA2 Twis ......"25868853
hsa-miR-33b-5p

sarcomametastasis; progression"MicroRNA 33b suppresses migration and invasion by ......"25546234



Reported gene related to hsa-miR-33b-5p

miRNAcancergenereportingPUBMED
hsa-miR-33b-5p

esophageal cancerHMGA2"The expression and significance of miR 33b and HMG ......"27609581
hsa-miR-33b-5p

melanomaHMGA2"By targeting HMGA2 and Twist1 miR-33b attenuated m ......"25868853
hsa-miR-33b-5p

melanomaHMGA2"MicroRNA 33b upregulated by EF24 a curcumin analog ......"25725129
hsa-miR-33b-5p

gastric cancerMYC"Ectopic expression of miR-33b in HGC-27 and MGC-80 ......"26729612
hsa-miR-33b-5p

sarcomaMYC"Moreover we also showed that c-Myc was negatively ......"25546234
hsa-miR-33b-5p

melanomaCDH2"miR-33b knockdown or ZEB1 overexpression reverted ......"25868853
hsa-miR-33b-5p

melanomaTWIST1"By targeting HMGA2 and Twist1 miR-33b attenuated m ......"25868853
hsa-miR-33b-5p

gastric cancerXIAP"The first stage of our studies showed that curcumi ......"27456358
hsa-miR-33b-5p

melanomaZEB1"miR-33b knockdown or ZEB1 overexpression reverted ......"25868853



Expression profile in cancer corhorts:




Putative target regulations

miRNAGeneCancerInteractionCorrelation beta
hsa-miR-33b-5p
STON1
9 cancers: CESC; COAD; ESCA; HNSC; LIHC; LUSC; PAAD; THCA; UCEC
MirTarget
TCGA CESC -0.293; TCGA COAD -0.474; TCGA ESCA -0.206; TCGA HNSC -0.092; TCGA LIHC -0.084; TCGA LUSC -0.114; TCGA PAAD -0.384; TCGA THCA -0.105; TCGA UCEC -0.445
hsa-miR-33b-5p
MEF2C
9 cancers: CESC; COAD; ESCA; HNSC; LIHC; LUSC; PAAD; THCA; UCEC
mirMAP
TCGA CESC -0.26; TCGA COAD -0.311; TCGA ESCA -0.244; TCGA HNSC -0.324; TCGA LIHC -0.076; TCGA LUSC -0.316; TCGA PAAD -0.206; TCGA THCA -0.068; TCGA UCEC -0.268
hsa-miR-33b-5p
EBF1
9 cancers: CESC; COAD; ESCA; HNSC; LIHC; LUSC; PAAD; THCA; UCEC
miRNATAP
TCGA CESC -0.346; TCGA COAD -0.268; TCGA ESCA -0.277; TCGA HNSC -0.219; TCGA LIHC -0.213; TCGA LUSC -0.257; TCGA PAAD -0.147; TCGA THCA -0.135; TCGA UCEC -0.189





Enriched cancer pathways of putative targets