miRNACancerMap

microRNA information: hsa-miR-410-3p

Reported expression in cancers: hsa-miR-410-3p

miRNA	cancer	regulation	reporting	PUBMED	method
hsa-miR-410-3p	breast cancer	downregulation	"miR-410-3p acts as an oncogene or tumor-suppressor ......"	27221455	qPCR
hsa-miR-410-3p	esophageal cancer	deregulation	"Differentially-expressed miRNAs were analyzed usin ......"	23534712	Reverse transcription PCR
hsa-miR-410-3p	lung squamous cell cancer	upregulation	"miR-410 acts as an oncogene or tumor suppressor ge ......"	26149213

Reported cancer pathway affected by hsa-miR-410-3p

miRNA	cancer	pathway	reporting	PUBMED	functional study
hsa-miR-410-3p	breast cancer	Epithelial mesenchymal transition pathway	"miR 410 3p suppresses breast cancer progression by ......"	27221455	Colony formation; MTT assay; Luciferase
hsa-miR-410-3p	pancreatic cancer	cell cycle pathway	"MicroRNA 410 functions as a tumor suppressor by ta ......"	25646808
hsa-miR-410-3p	sarcoma	Apoptosis pathway	"VEGF mediated suppression of cell proliferation an ......"	25385479	Western blot; Luciferase; Flow cytometry; MTT assay

Reported cancer prognosis affected by hsa-miR-410-3p

miRNA	cancer	prognosis	reporting	PUBMED	functional study
hsa-miR-410-3p	breast cancer	progression	"miR 410 3p suppresses breast cancer progression by ......"	27221455	Colony formation; MTT assay; Luciferase
hsa-miR-410-3p	gastric cancer	metastasis	"MicroRNA 410 suppresses migration and invasion by ......"	25136862	Luciferase
hsa-miR-410-3p	lung squamous cell cancer	progression	"MicroRNA 410 promotes cell proliferation by target ......"	26149213
hsa-miR-410-3p	ovarian cancer	poor survival; staging	"RNA from a training set of 62 cases was hybridized ......"	21354599

Reported gene related to hsa-miR-410-3p

miRNA	cancer	gene	reporting	PUBMED
hsa-miR-410-3p	pancreatic cancer	AGT	"MicroRNA 410 functions as a tumor suppressor by ta ......"	25646808
hsa-miR-410-3p	pancreatic cancer	AGTR1	"In contrast inhibition of miR-410 increased the ex ......"	25646808
hsa-miR-410-3p	lung squamous cell cancer	BRD7	"MicroRNA 410 promotes cell proliferation by target ......"	26149213
hsa-miR-410-3p	colorectal cancer	DNMT3A	"Furthermore both miR-410 and DNMT3A are upregulate ......"	25272045
hsa-miR-410-3p	colorectal cancer	FHL1	"MiR 410 is overexpressed in liver and colorectal t ......"	25272045
hsa-miR-410-3p	ovarian cancer	MAPK1IP1L	"The data suggest that an MiSS that contains miR-41 ......"	21354599
hsa-miR-410-3p	gastric cancer	MDM2	"MicroRNA 410 suppresses migration and invasion by ......"	25136862
hsa-miR-410-3p	pancreatic cancer	PECAM1	"miR-410 overexpression inhibited angiogenesis in m ......"	25646808
hsa-miR-410-3p	breast cancer	SNAI1	"miR 410 3p suppresses breast cancer progression by ......"	27221455
hsa-miR-410-3p	sarcoma	VEGFA	"VEGF mediated suppression of cell proliferation an ......"	25385479

Expression profile in cancer corhorts:

Putative target regulations

miRNA	Gene	Cancer	Interaction	Correlation beta
hsa-miR-410-3p	FMR1	9 cancers: BLCA; BRCA; ESCA; HNSC; LIHC; LUSC; OV; SARC; STAD	MirTarget	TCGA BLCA -0.09; TCGA BRCA -0.115; TCGA ESCA -0.084; TCGA HNSC -0.078; TCGA LIHC -0.084; TCGA LUSC -0.074; TCGA OV -0.075; TCGA SARC -0.057; TCGA STAD -0.067
hsa-miR-410-3p	BPNT1	9 cancers: BRCA; CESC; ESCA; HNSC; OV; PAAD; PRAD; STAD; UCEC	MirTarget	TCGA BRCA -0.115; TCGA CESC -0.055; TCGA ESCA -0.101; TCGA HNSC -0.064; TCGA OV -0.063; TCGA PAAD -0.109; TCGA PRAD -0.071; TCGA STAD -0.085; TCGA UCEC -0.076

Enriched cancer pathways of putative targets