miRNACancerMap

microRNA information: hsa-miR-493-5p

Reported expression in cancers: hsa-miR-493-5p

miRNA	cancer	regulation	reporting	PUBMED	method
hsa-miR-493-5p	breast cancer	deregulation	"For identification of differentially expressed mic ......"	20331864	qPCR
hsa-miR-493-5p	colon cancer	upregulation	"Functional analyses showed that miR-493 and to a l ......"	22373578
hsa-miR-493-5p	gastric cancer	downregulation	"Tissue samples obtained from 36 gastric cancer pat ......"	26730339	qPCR; Microarray; in situ hybridization

Reported cancer pathway affected by hsa-miR-493-5p

miRNA	cancer	pathway	reporting	PUBMED	functional study

Reported cancer prognosis affected by hsa-miR-493-5p

miRNA	cancer	prognosis	reporting	PUBMED	functional study
hsa-miR-493-5p	bladder cancer	motility	"Tumor suppressor microRNA 493 decreases cell motil ......"	22057916	Luciferase
hsa-miR-493-5p	colon cancer	tumorigenesis; metastasis	"miR 493 induction during carcinogenesis blocks met ......"	22373578
hsa-miR-493-5p	colon cancer	metastasis	"MKK7 mediates miR 493 dependent suppression of liv ......"	24533778	RNAi
hsa-miR-493-5p	gastric cancer	cell migration; staging; metastasis; progression; poor survival	"MiR 493 suppresses the proliferation and invasion ......"	26730339	Wound Healing Assay
hsa-miR-493-5p	gastric cancer	drug resistance	"miR 493 mediated DKK1 down regulation confers prol ......"	26799283
hsa-miR-493-5p	lung cancer	metastasis; progression	"MicroRNA 493 suppresses tumor growth invasion and ......"	25105419

Reported gene related to hsa-miR-493-5p

miRNA	cancer	gene	reporting	PUBMED
hsa-miR-493-5p	colon cancer	IGF1R	"We previously showed that IGF1R is a target gene o ......"	24533778
hsa-miR-493-5p	colon cancer	IGF1R	"IGF1R was identified as a direct target of miR-493 ......"	22373578
hsa-miR-493-5p	bladder cancer	RHOC	"Tumor suppressor microRNA 493 decreases cell motil ......"	22057916
hsa-miR-493-5p	gastric cancer	RHOC	"MiR 493 suppresses the proliferation and invasion ......"	26730339
hsa-miR-493-5p	gastric cancer	DKK1	"miR 493 mediated DKK1 down regulation confers prol ......"	26799283
hsa-miR-493-5p	lung cancer	E2F1	"MicroRNA 493 suppresses tumor growth invasion and ......"	25105419
hsa-miR-493-5p	gastric cancer	FRTS1	"Moreover miR-493 might independently predict OS an ......"	26730339
hsa-miR-493-5p	breast cancer	FUT4	"miR 493 5p attenuates the invasiveness and tumorig ......"	27375041
hsa-miR-493-5p	bladder cancer	FZD4	"Tumor suppressor microRNA 493 decreases cell motil ......"	22057916
hsa-miR-493-5p	chronic myeloid leukemia	IL8	"These criteria narrowed our candidate gene-miRNA t ......"	25506832
hsa-miR-493-5p	colon cancer	MAP2K7	"MKK7 mediates miR 493 dependent suppression of liv ......"	24533778

Expression profile in cancer corhorts:

Putative target regulations

miRNA	Gene	Cancer	Interaction	Correlation beta
hsa-miR-493-5p	STXBP3	9 cancers: BLCA; BRCA; COAD; ESCA; HNSC; OV; SARC; STAD; UCEC	MirTarget	TCGA BLCA -0.073; TCGA BRCA -0.052; TCGA COAD -0.097; TCGA ESCA -0.07; TCGA HNSC -0.05; TCGA OV -0.053; TCGA SARC -0.067; TCGA STAD -0.086; TCGA UCEC -0.106
hsa-miR-493-5p	PDK4	9 cancers: BRCA; ESCA; KIRC; LIHC; LUAD; LUSC; PRAD; SARC; STAD	MirTarget	TCGA BRCA -0.213; TCGA ESCA -0.765; TCGA KIRC -0.159; TCGA LIHC -0.155; TCGA LUAD -0.161; TCGA LUSC -0.268; TCGA PRAD -0.221; TCGA SARC -0.164; TCGA STAD -0.753
hsa-miR-493-5p	VAMP2	9 cancers: BRCA; COAD; ESCA; LUAD; LUSC; OV; PAAD; PRAD; STAD	miRNATAP	TCGA BRCA -0.14; TCGA COAD -0.125; TCGA ESCA -0.097; TCGA LUAD -0.062; TCGA LUSC -0.116; TCGA OV -0.071; TCGA PAAD -0.149; TCGA PRAD -0.094; TCGA STAD -0.202
hsa-miR-493-5p	MPP7	10 cancers: COAD; ESCA; HNSC; LUAD; LUSC; OV; PAAD; SARC; STAD; UCEC	MirTarget	TCGA COAD -0.202; TCGA ESCA -0.228; TCGA HNSC -0.124; TCGA LUAD -0.112; TCGA LUSC -0.153; TCGA OV -0.143; TCGA PAAD -0.289; TCGA SARC -0.505; TCGA STAD -0.475; TCGA UCEC -0.131

Enriched cancer pathways of putative targets