microRNA information: hsa-miR-539-5p

SectionIDlink
Mature name: hsa-miR-539-5pmiRbase
Accession: MIMAT0003163miRbase
Precursor name: hsa-mir-539 miRbase
Precursor accession: MI0003514miRbase
Symbol: MIR539HGNC
RefSeq ID: NR_030256GenBank
Sequence: GGAGAAAUUAUCCUUGGUGUGU


Reported expression in cancers: hsa-miR-539-5p

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-539-5p

sarcomadownregulation"The expression levels of miR-133a and miR-539 were ......"26388701qPCR


Reported cancer pathway affected by hsa-miR-539-5p

miRNAcancerpathwayreportingPUBMEDfunctional study


Reported cancer prognosis affected by hsa-miR-539-5p

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-539-5p

colon cancerstaging"We assessed by qRT-PCR expression of 754 microRNAs ......"27485175
hsa-miR-539-5p

prostate cancerprogression; metastasis"miR 539 inhibits prostate cancer progression by di ......"27037000Luciferase
hsa-miR-539-5p

sarcomatumorigenesis"MicroRNA 539 suppresses osteosarcoma cell invasion ......"26339374Luciferase
hsa-miR-539-5p

sarcomaworse prognosis; staging; metastasis; recurrence; poor survival; progression"Down regulation of miR 133a and miR 539 are associ ......"26388701
hsa-miR-539-5p

thyroid cancercell migration"MiR 539 inhibits thyroid cancer cell migration and ......"26206083Luciferase


Reported gene related to hsa-miR-539-5p

miRNAcancergenereportingPUBMED
hsa-miR-539-5p

thyroid cancerCARD11"MiR 539 inhibits thyroid cancer cell migration and ......"26206083
hsa-miR-539-5p

sarcomaMMP8"We also identified that MMP8 was a direct target o ......"26339374
hsa-miR-539-5p

prostate cancerSPAG5"miR 539 inhibits prostate cancer progression by di ......"27037000


Expression profile in cancer corhorts:



Putative target regulations

miRNAGeneCancerInteractionCorrelation beta
hsa-miR-539-5p
ZNF862
9 cancers: BLCA; BRCA; ESCA; KIRC; LGG; LIHC; LUSC; OV; STAD
mirMAP
TCGA BLCA -0.111; TCGA BRCA -0.094; TCGA ESCA -0.129; TCGA KIRC -0.096; TCGA LGG -0.091; TCGA LIHC -0.088; TCGA LUSC -0.098; TCGA OV -0.125; TCGA STAD -0.098
hsa-miR-539-5p
TP53INP1
9 cancers: BLCA; COAD; HNSC; KIRC; LGG; LUSC; OV; SARC; STAD
mirMAP
TCGA BLCA -0.079; TCGA COAD -0.125; TCGA HNSC -0.054; TCGA KIRC -0.082; TCGA LGG -0.146; TCGA LUSC -0.067; TCGA OV -0.06; TCGA SARC -0.079; TCGA STAD -0.111
hsa-miR-539-5p
NRBP2
10 cancers: BLCA; BRCA; CESC; KIRC; LIHC; LUSC; OV; PAAD; SARC; STAD
mirMAP
TCGA BLCA -0.073; TCGA BRCA -0.085; TCGA CESC -0.107; TCGA KIRC -0.185; TCGA LIHC -0.091; TCGA LUSC -0.075; TCGA OV -0.135; TCGA PAAD -0.106; TCGA SARC -0.143; TCGA STAD -0.127




Enriched cancer pathways of putative targets