microRNA information: hsa-miR-577
| Section | ID | link |
|---|---|---|
| Mature name: | hsa-miR-577 | miRbase |
| Accession: | MIMAT0003242 | miRbase |
| Precursor name: | hsa-mir-577 | miRbase |
| Precursor accession: | MI0003584 | miRbase |
| Symbol: | MIR577 | HGNC |
| RefSeq ID: | NR_030303 | GenBank |
| Sequence: | UAGAUAAAAUAUUGGUACCUG |
Reported expression in cancers: hsa-miR-577
| miRNA | cancer | regulation | reporting | PUBMED | method |
|---|---|---|---|---|---|
| hsa-miR-577 | glioblastoma | downregulation | "miR 577 inhibits glioblastoma tumor growth via the ......" | 25764520 |
Reported cancer pathway affected by hsa-miR-577
| miRNA | cancer | pathway | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-miR-577 | gastric cancer | cell cycle pathway | "MicroRNA 577 inhibits gastric cancer growth by tar ......" | 26622688 | Western blot; Luciferase |
| hsa-miR-577 | glioblastoma | Wnt signaling pathway | "miR 577 inhibits glioblastoma tumor growth via the ......" | 25764520 | Western blot |
Reported cancer prognosis affected by hsa-miR-577
| miRNA | cancer | prognosis | reporting | PUBMED | functional study |
|---|
Reported gene related to hsa-miR-577
| miRNA | cancer | gene | reporting | PUBMED |
|---|---|---|---|---|
| hsa-miR-577 | glioblastoma | LRP6 | "miR-577 down-regulation was associated with increa ......" | 25764520 |
| hsa-miR-577 | gastric cancer | TCF3 | "MicroRNA 577 inhibits gastric cancer growth by tar ......" | 26622688 |
| hsa-miR-577 | esophageal cancer | TSGA10 | "Effects and interactions of MiR 577 and TSGA10 in ......" | 24294352 |
Expression profile in cancer corhorts:
Putative target regulations
| miRNA | Gene | Cancer | Interaction | Correlation beta |
|---|---|---|---|---|
hsa-miR-577 | CLEC2B | 9 cancers: COAD; ESCA; KIRC; LGG; LUSC; PAAD; THCA; STAD; UCEC | MirTarget | TCGA COAD -0.268; TCGA ESCA -0.324; TCGA KIRC -0.254; TCGA LGG -0.152; TCGA LUSC -0.207; TCGA PAAD -0.162; TCGA THCA -0.163; TCGA STAD -0.158; TCGA UCEC -0.179 |
hsa-miR-577 | TMEM45A | 9 cancers: COAD; ESCA; KIRC; KIRP; LGG; LUSC; PAAD; STAD; UCEC | MirTarget | TCGA COAD -0.309; TCGA ESCA -0.392; TCGA KIRC -0.308; TCGA KIRP -0.151; TCGA LGG -0.058; TCGA LUSC -0.166; TCGA PAAD -0.225; TCGA STAD -0.091; TCGA UCEC -0.091 |
hsa-miR-577 | LAMC1 | 9 cancers: COAD; ESCA; KIRC; KIRP; LGG; PAAD; THCA; STAD; UCEC | PITA | TCGA COAD -0.136; TCGA ESCA -0.067; TCGA KIRC -0.056; TCGA KIRP -0.092; TCGA LGG -0.114; TCGA PAAD -0.121; TCGA THCA -0.079; TCGA STAD -0.117; TCGA UCEC -0.051 |
hsa-miR-577 | MAP3K12 | 9 cancers: COAD; ESCA; KIRC; KIRP; LUSC; PAAD; THCA; STAD; UCEC | PITA | TCGA COAD -0.26; TCGA ESCA -0.117; TCGA KIRC -0.17; TCGA KIRP -0.118; TCGA LUSC -0.059; TCGA PAAD -0.138; TCGA THCA -0.061; TCGA STAD -0.069; TCGA UCEC -0.109 |
hsa-miR-577 | YPEL4 | 9 cancers: COAD; ESCA; KIRC; KIRP; LUSC; PAAD; THCA; STAD; UCEC | PITA | TCGA COAD -0.416; TCGA ESCA -0.168; TCGA KIRC -0.217; TCGA KIRP -0.164; TCGA LUSC -0.089; TCGA PAAD -0.184; TCGA THCA -0.355; TCGA STAD -0.165; TCGA UCEC -0.195 |
hsa-miR-577 | LOX | 9 cancers: COAD; ESCA; KIRC; KIRP; LGG; LUSC; PAAD; THCA; STAD | mirMAP | TCGA COAD -0.342; TCGA ESCA -0.222; TCGA KIRC -0.419; TCGA KIRP -0.171; TCGA LGG -0.111; TCGA LUSC -0.086; TCGA PAAD -0.327; TCGA THCA -0.351; TCGA STAD -0.069 |
hsa-miR-577 | CDH11 | 9 cancers: COAD; ESCA; KIRC; LGG; LUSC; PAAD; THCA; STAD; UCEC | mirMAP | TCGA COAD -0.336; TCGA ESCA -0.187; TCGA KIRC -0.1; TCGA LGG -0.06; TCGA LUSC -0.083; TCGA PAAD -0.319; TCGA THCA -0.508; TCGA STAD -0.104; TCGA UCEC -0.084 |
hsa-miR-577 | RAB31 | 10 cancers: COAD; ESCA; KIRC; KIRP; LGG; LUSC; PAAD; THCA; STAD; UCEC | mirMAP | TCGA COAD -0.385; TCGA ESCA -0.285; TCGA KIRC -0.111; TCGA KIRP -0.081; TCGA LGG -0.063; TCGA LUSC -0.19; TCGA PAAD -0.267; TCGA THCA -0.142; TCGA STAD -0.18; TCGA UCEC -0.142 |
hsa-miR-577 | ANTXR1 | 9 cancers: COAD; ESCA; KIRC; KIRP; LGG; LUSC; PAAD; STAD; UCEC | mirMAP | TCGA COAD -0.475; TCGA ESCA -0.232; TCGA KIRC -0.155; TCGA KIRP -0.138; TCGA LGG -0.059; TCGA LUSC -0.065; TCGA PAAD -0.268; TCGA STAD -0.136; TCGA UCEC -0.088 |
hsa-miR-577 | CMKLR1 | 9 cancers: COAD; ESCA; KIRC; LGG; LUSC; PAAD; THCA; STAD; UCEC | mirMAP | TCGA COAD -0.248; TCGA ESCA -0.132; TCGA KIRC -0.114; TCGA LGG -0.062; TCGA LUSC -0.152; TCGA PAAD -0.216; TCGA THCA -0.091; TCGA STAD -0.089; TCGA UCEC -0.174 |
hsa-miR-577 | THSD1 | 9 cancers: COAD; ESCA; KIRC; KIRP; LGG; LUSC; PAAD; STAD; UCEC | miRNATAP | TCGA COAD -0.193; TCGA ESCA -0.204; TCGA KIRC -0.133; TCGA KIRP -0.094; TCGA LGG -0.062; TCGA LUSC -0.182; TCGA PAAD -0.089; TCGA STAD -0.133; TCGA UCEC -0.086 |
hsa-miR-577 | RASGRP4 | 9 cancers: COAD; ESCA; KIRC; KIRP; LUSC; PAAD; THCA; STAD; UCEC | miRNATAP | TCGA COAD -0.237; TCGA ESCA -0.158; TCGA KIRC -0.245; TCGA KIRP -0.11; TCGA LUSC -0.292; TCGA PAAD -0.158; TCGA THCA -0.186; TCGA STAD -0.101; TCGA UCEC -0.066 |
Enriched cancer pathways of putative targets