microRNA information: hsa-miR-99b-5p

SectionIDlink
Mature name: hsa-miR-99b-5pmiRbase
Accession: MIMAT0000689miRbase
Precursor name: hsa-mir-99b miRbase
Precursor accession: MI0000746miRbase
Symbol: MIR99BHGNC
RefSeq ID: NR_029843GenBank
Sequence: CACCCGUAGAACCGACCUUGCG


Reported expression in cancers: hsa-miR-99b-5p

miRNAcancerregulationreportingPUBMEDmethod
hsa-miR-99b-5p

colorectal cancerupregulation"miR-99b-5p was found to be more than 6-fold higher ......"26259252
hsa-miR-99b-5p

esophageal cancerderegulation"The expression profiles of miRNAs in paired EC and ......"23761828Microarray; qPCR
hsa-miR-99b-5p

lung squamous cell cancerdownregulation"microRNA 99b acts as a tumor suppressor in non sma ......"22969861Microarray
hsa-miR-99b-5p

prostate cancerdownregulation"PCR array was performed in FFPE PCa tissues 5 Cauc ......"24167554qPCR
hsa-miR-99b-5p

sarcomaupregulation"There were 21 significantly up-regulated miRNAs in ......"21213367


Reported cancer pathway affected by hsa-miR-99b-5p

miRNAcancerpathwayreportingPUBMEDfunctional study
hsa-miR-99b-5p

head and neck cancermTOR signaling pathway"Selected microRNAs including members of miR-99 fam ......"22425712


Reported cancer prognosis affected by hsa-miR-99b-5p

miRNAcancerprognosisreportingPUBMEDfunctional study
hsa-miR-99b-5p

breast cancertumorigenesis"Microarray-based techniques are being useful to ob ......"22167321
hsa-miR-99b-5p

colorectal cancermetastasis; staging; poor survival; cell migration"miR-99b-5p was found to be more than 6-fold higher ......"26259252Luciferase
hsa-miR-99b-5p

colorectal cancerpoor survival"A total of 1893 carcinoma samples were run on the ......"27198570
hsa-miR-99b-5p

head and neck cancertumorigenesis"Selected microRNAs including members of miR-99 fam ......"22425712
hsa-miR-99b-5p

kidney renal cell cancerdrug resistance; progression; poor survival"MiR 99b 5p expression and response to tyrosine kin ......"27738339
hsa-miR-99b-5p

liver cancermetastasis; poor survival; recurrence"miR 99b promotes metastasis of hepatocellular carc ......"26134929Luciferase
hsa-miR-99b-5p

pancreatic cancerdrug resistance"miR 99b targeted mTOR induction contributes to irr ......"23886294Western blot
hsa-miR-99b-5p

prostate cancerstaging; worse prognosis"miR 99 family of MicroRNAs suppresses the expressi ......"21212412
hsa-miR-99b-5p

prostate cancerdrug resistance"The miR-99 family has been shown to play an import ......"27340920


Reported gene related to hsa-miR-99b-5p

miRNAcancergenereportingPUBMED
hsa-miR-99b-5p

colorectal cancerMTOR"Besides miR-99b-5p silencing in miR-99b-5p-positiv ......"26259252
hsa-miR-99b-5p

head and neck cancerMTOR"Furthermore ectopic transfection of miR-99 family ......"22425712
hsa-miR-99b-5p

pancreatic cancerMTOR"miR 99b targeted mTOR induction contributes to irr ......"23886294
hsa-miR-99b-5p

prostate cancerSMARCA5"The miR-99 family has been shown to play an import ......"27340920
hsa-miR-99b-5p

prostate cancerSMARCA5"We determined that PSA is posttranscriptionally re ......"21212412
hsa-miR-99b-5p

liver cancerCLDN11"Furthermore using a dual‑luciferase assay we dem ......"26134929
hsa-miR-99b-5p

lung squamous cell cancerFGFR3"miR-99b was downregulated and FGFR3 was upregulate ......"22969861
hsa-miR-99b-5p

head and neck cancerIGF1R"Furthermore ectopic transfection of miR-99 family ......"22425712
hsa-miR-99b-5p

prostate cancerSMARCD1"The miR-99 family has been shown to play an import ......"27340920
hsa-miR-99b-5p

cervical and endocervical cancerTRIB2"miR 99 inhibits cervical carcinoma cell proliferat ......"24137458
hsa-miR-99b-5p

kidney renal cell cancerTXK"MiR 99b 5p expression and response to tyrosine kin ......"27738339


Expression profile in cancer corhorts:



Putative target regulations

miRNAGeneCancerInteractionCorrelation beta
hsa-miR-99b-5p
ALDH1B1
9 cancers: BLCA; COAD; LGG; LIHC; LUAD; PAAD; SARC; THCA; UCEC
miRNAWalker2 validate
TCGA BLCA -0.348; TCGA COAD -0.164; TCGA LGG -0.2; TCGA LIHC -0.22; TCGA LUAD -0.096; TCGA PAAD -0.242; TCGA SARC -0.942; TCGA THCA -0.132; TCGA UCEC -0.121
hsa-miR-99b-5p
EEF2
14 cancers: BLCA; BRCA; CESC; COAD; ESCA; HNSC; LGG; LIHC; LUAD; LUSC; OV; PAAD; PRAD; STAD
miRNAWalker2 validate
TCGA BLCA -0.127; TCGA BRCA -0.171; TCGA CESC -0.097; TCGA COAD -0.103; TCGA ESCA -0.123; TCGA HNSC -0.138; TCGA LGG -0.272; TCGA LIHC -0.101; TCGA LUAD -0.066; TCGA LUSC -0.117; TCGA OV -0.249; TCGA PAAD -0.13; TCGA PRAD -0.103; TCGA STAD -0.16
hsa-miR-99b-5p
RNF213
10 cancers: BLCA; CESC; ESCA; HNSC; KIRC; KIRP; LIHC; LUAD; SARC; THCA
miRNAWalker2 validate
TCGA BLCA -0.137; TCGA CESC -0.259; TCGA ESCA -0.16; TCGA HNSC -0.147; TCGA KIRC -0.149; TCGA KIRP -0.19; TCGA LIHC -0.085; TCGA LUAD -0.194; TCGA SARC -0.136; TCGA THCA -0.304
hsa-miR-99b-5p
MBNL1
11 cancers: BLCA; CESC; COAD; HNSC; LUAD; LUSC; OV; SARC; THCA; STAD; UCEC
MirTarget; miRNATAP
TCGA BLCA -0.224; TCGA CESC -0.103; TCGA COAD -0.07; TCGA HNSC -0.11; TCGA LUAD -0.08; TCGA LUSC -0.087; TCGA OV -0.113; TCGA SARC -0.465; TCGA THCA -0.137; TCGA STAD -0.171; TCGA UCEC -0.246
hsa-miR-99b-5p
EDF1
10 cancers: BRCA; ESCA; KIRC; KIRP; LGG; LIHC; LUSC; PAAD; PRAD; UCEC
miRNAWalker2 validate
TCGA BRCA -0.236; TCGA ESCA -0.187; TCGA KIRC -0.296; TCGA KIRP -0.222; TCGA LGG -0.065; TCGA LIHC -0.165; TCGA LUSC -0.105; TCGA PAAD -0.291; TCGA PRAD -0.13; TCGA UCEC -0.134
hsa-miR-99b-5p
RPS2
10 cancers: BRCA; ESCA; KIRC; KIRP; LGG; LUAD; LUSC; OV; PAAD; THCA
miRNAWalker2 validate
TCGA BRCA -0.099; TCGA ESCA -0.157; TCGA KIRC -0.326; TCGA KIRP -0.156; TCGA LGG -0.198; TCGA LUAD -0.099; TCGA LUSC -0.108; TCGA OV -0.158; TCGA PAAD -0.413; TCGA THCA -0.145
hsa-miR-99b-5p
ETV6
9 cancers: ESCA; KIRC; KIRP; LUAD; OV; PAAD; SARC; THCA; STAD
miRNAWalker2 validate
TCGA ESCA -0.124; TCGA KIRC -0.313; TCGA KIRP -0.193; TCGA LUAD -0.102; TCGA OV -0.182; TCGA PAAD -0.121; TCGA SARC -0.161; TCGA THCA -0.079; TCGA STAD -0.122




Enriched cancer pathways of putative targets