| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Focal adhesion |
16 genes: COL1A2, COL4A1, COL4A4, DOCK1, FYN, HGF, IGF1, MYLK, PPP1R12A, PDGFRA, PPP1CB, RAP1A, ROCK1, THBS1, CCND2, ROCK2
|
5.122e-05 |
| Wnt signaling pathway |
12 genes: NFAT5, PRICKLE2, LRP6, PLCB4, PRKACB, ROCK1, SFRP2, FZD3, AXIN2, FZD4, CCND2, ROCK2
|
0.0004621 |
| Ras signaling pathway |
15 genes: FGF2, FGF7, FGF13, IGF1, HGF, FGFR2, INSR, PDGFRA, KIT, GAB1, PRKACB, RASGRF2, GRIN2A, SHOC2, RAP1A
|
0.001022 |
| MAPK signaling pathway |
16 genes: MAP3K8, FGF2, FGF7, FGF13, FGFR2, CACNG4, MEF2C, PDGFRA, PRKACB, RAP1A, RASGRF2, TGFB3, CACNA1C, CACNA2D1, CACNB2, MAP4K3
|
0.001361 |
| TGF.beta signaling pathway |
8 genes: ID2, INHBB, SMAD9, ROCK1, BMPR2, TGFB3, THBS1, ROCK2
|
0.001372 |
| Axon guidance |
10 genes: NFAT5, CFL2, EPHA3, EPHA7, SEMA3D, FYN, ABLIM1, ROCK1, UNC5C, ROCK2
|
0.001722 |
| Hippo signaling pathway |
11 genes: AMOT, YAP1, PPP1CB, TEAD1, TGFB3, BMPR2, ID2, FZD3, FZD4, AXIN2, CCND2
|
0.001875 |
| Long.term potentiation |
7 genes: GRIN2A, PPP1R12A, PLCB4, PPP1CB, PRKACB, RAP1A, CACNA1C
|
0.001907 |
| Vascular smooth muscle contraction |
9 genes: MYLK, PPP1R12A, PLCB4, PPP1CB, PRKACB, PRKCE, ROCK1, CACNA1C, ROCK2
|
0.002723 |
| ABC transporters |
5 genes: ABCC9, ABCC4, ABCA1, ABCD2, ABCD3
|
0.004855 |
| ECM.receptor interaction |
7 genes: COL1A2, COL4A1, COL4A4, GP1BA, SDC2, THBS1, SV2B
|
0.005691 |
| Regulation of actin cytoskeleton |
12 genes: CFL2, DOCK1, FGF2, FGF7, FGF13, FGFR2, MYLK, PPP1R12A, PDGFRA, PPP1CB, ROCK1, ROCK2
|
0.008419 |
| Insulin signaling pathway |
9 genes: SORBS1, FOXO1, INSR, PPP1CB, PRKAA2, PRKAB2, PRKACB, PRKAR2B, CBLB
|
0.008447 |
| Adherens junction |
6 genes: SORBS1, WASF3, FYN, INSR, PTPRB, SNAI1
|
0.01029 |
| Hedgehog signaling pathway |
5 genes: GAS1, RAB23, PRKACB, PTCH1, HHIP
|
0.01336 |
| Jak.STAT signaling pathway |
9 genes: SPRY1, SPRY2, IL6ST, LEPR, LIFR, PRLR, CBLB, CCND2, SOCS5
|
0.01709 |
| PI3K AKT signaling pathway |
16 genes: FGF2, FGF7, FGF13, IGF1, HGF, FGFR2, INSR, PDGFRA, KIT, PRLR, COL1A2, COL4A4, COL4A1, THBS1, PRKAA2, CCND2
|
0.01722 |
| Cell adhesion molecules .CAMs. |
8 genes: CNTN1, NLGN1, NFASC, NCAM1, SDC2, SELE, VCAM1, NRXN1
|
0.02224 |
| Endocytosis |
10 genes: FGFR2, RAB11FIP2, DNM3, GRK5, KIT, NEDD4, PDGFRA, TGFB3, PSD2, CBLB
|
0.03389 |
| Melanogenesis |
6 genes: KIT, MITF, PLCB4, PRKACB, FZD3, FZD4
|
0.04285 |
| Cardiac muscle contraction |
5 genes: CACNG4, TPM1, CACNA1C, CACNA2D1, CACNB2
|
0.04519 |