| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Ras signaling pathway |
15 genes: FGF2, FGF7, FGF13, BDNF, IGF1, HGF, FGFR2, INSR, PDGFRA, KIT, PRKACB, GRIN2A, SHOC2, RAP1A, RAP1B
|
2.999e-05 |
| MAPK signaling pathway |
16 genes: MAP3K8, FGF2, FGF7, FGF13, FGFR2, CACNG4, MEF2C, PDGFRA, PRKACB, RAP1A, RAP1B, BDNF, TGFB3, CACNA1C, CACNB2, MAP4K3
|
3.515e-05 |
| Long.term potentiation |
7 genes: GRIN2A, PPP1R12A, PLCB4, PRKACB, RAP1A, RAP1B, CACNA1C
|
0.0002797 |
| Calcium signaling pathway |
10 genes: CHRM3, ERBB4, GRIN2A, MYLK, PDE1C, PDGFRA, PLCB4, PRKACB, BST1, CACNA1C
|
0.001545 |
| Wnt signaling pathway |
9 genes: PRICKLE2, LRP6, PLCB4, PRKACB, SFRP2, FZD3, AXIN2, FZD4, CCND2
|
0.00182 |
| PI3K AKT signaling pathway |
15 genes: FGF2, FGF7, FGF13, BDNF, IGF1, HGF, FGFR2, INSR, PDGFRA, KIT, PRLR, COL4A4, COL9A1, PRKAA2, CCND2
|
0.002058 |
| Hedgehog signaling pathway |
5 genes: RAB23, PRKACB, PTCH1, HHIP, SMO
|
0.003469 |
| Focal adhesion |
10 genes: COL4A4, FYN, HGF, IGF1, MYLK, PPP1R12A, PDGFRA, RAP1A, RAP1B, CCND2
|
0.003752 |
| Vascular smooth muscle contraction |
7 genes: KCNMB4, MYLK, PPP1R12A, PLCB4, PRKACB, PRKCE, CACNA1C
|
0.005352 |
| Hippo signaling pathway |
8 genes: AMOT, TEAD1, TGFB3, ID2, FZD3, FZD4, AXIN2, CCND2
|
0.007311 |
| ABC transporters |
4 genes: ABCC9, ABCA1, ABCD2, ABCD3
|
0.008258 |
| Adherens junction |
5 genes: SORBS1, WASF3, FYN, INSR, PTPRB
|
0.01063 |
| Gastric acid secretion |
5 genes: CHRM3, KCNJ16, MYLK, PLCB4, PRKACB
|
0.01123 |
| Endocytosis |
9 genes: ERBB4, FGFR2, RAB11FIP2, GRK5, KIT, PDGFRA, TGFB3, PSD2, RAB11B
|
0.01231 |
| Cardiac muscle contraction |
5 genes: CACNG4, TPM1, UQCRB, CACNA1C, CACNB2
|
0.01319 |
| Regulation of actin cytoskeleton |
9 genes: CFL2, CHRM3, FGF2, FGF7, FGF13, FGFR2, MYLK, PPP1R12A, PDGFRA
|
0.01683 |
| p53 signaling pathway |
4 genes: IGF1, IGFBP3, CCND2, CCNG2
|
0.03703 |
| Melanogenesis |
5 genes: KIT, PLCB4, PRKACB, FZD3, FZD4
|
0.03733 |
| Pancreatic secretion |
5 genes: CHRM3, PLCB4, RAP1A, RAP1B, BST1
|
0.03733 |
| Cell adhesion molecules .CAMs. |
6 genes: CNTN1, NLGN1, NCAM1, SDC2, SELE, NRXN1
|
0.03833 |