| Enriched cancer pathway | Genes under regulation | P value |
|---|
| PI3K AKT signaling pathway |
14 genes: NGF, PDGFA, PDGFB, IGF1R, OSMR, COL1A1, COL1A2, THBS1, ITGB3, PRKAA2, PPP2R2A, CDKN1A, CREB3L2, NR4A1
|
3.314e-05 |
| MAPK signaling pathway |
11 genes: RASGRP1, MAP3K2, NR4A1, NGF, PDGFA, PDGFB, TAOK1, RPS6KA3, TGFBR1, CACNB4, MAP4K4
|
0.0001816 |
| ECM.receptor interaction |
6 genes: COL1A1, COL1A2, COL3A1, COL5A2, ITGB3, THBS1
|
0.0003344 |
| Focal adhesion |
9 genes: COL1A1, COL1A2, COL3A1, COL5A2, IGF1R, ITGB3, PDGFA, PDGFB, THBS1
|
0.0003594 |
| Protein digestion and absorption |
5 genes: COL1A1, COL1A2, COL3A1, COL5A2, SLC8A2
|
0.001923 |
| TGF.beta signaling pathway |
5 genes: DCN, GDF6, TGFBR1, THBS1, CHRD
|
0.002378 |
| Calcium signaling pathway |
7 genes: ADCY9, ADRB2, ADRB3, GNAL, PTAFR, SLC8A2, CALM1
|
0.003337 |
| Ras signaling pathway |
8 genes: NGF, PDGFA, PDGFB, IGF1R, RASGRP1, CALM1, RALB, ABL2
|
0.004466 |
| Melanogenesis |
5 genes: ADCY9, EDN1, CREB3L2, CALM1, FZD4
|
0.004993 |
| Oocyte meiosis |
5 genes: ADCY9, IGF1R, RPS6KA3, CPEB1, CALM1
|
0.008265 |
| Neurotrophin signaling pathway |
5 genes: NGF, NTRK3, RPS6KA3, CALM1, IRS2
|
0.01279 |
| Progesterone.mediated oocyte maturation |
4 genes: ADCY9, IGF1R, RPS6KA3, CPEB1
|
0.01513 |
| Salivary secretion |
4 genes: ADCY9, ADRB2, ADRB3, CALM1
|
0.01632 |
| Gap junction |
4 genes: MAP3K2, ADCY9, PDGFA, PDGFB
|
0.01693 |
| mTOR signaling pathway |
3 genes: PRKAA2, RPS6KA3, ULK2
|
0.01908 |
| Endocytosis |
6 genes: ADRB2, ADRB3, IGF1R, SMAP2, TGFBR1, EEA1
|
0.02411 |
| Glycosaminoglycan biosynthesis . heparan sulfate |
2 genes: XYLT1, NDST2
|
0.03237 |