Enriched cancer pathwayGenes under regulationP value
Long.term potentiation
8 genes: GRIN2A, PPP1R12A, PLCB4, PPP1CC, PRKACB, RAP1A, RAP1B, CACNA1C
9.214e-05
Ras signaling pathway
14 genes: FGF2, FGF7, FGF12, FGF13, IGF1, HGF, INSR, PDGFRA, KIT, PRKACB, GRIN2A, SHOC2, RAP1A, RAP1B
0.0003984
Focal adhesion
11 genes: COL4A4, DOCK1, HGF, IGF1, MYLK, PPP1R12A, PDGFRA, PPP1CC, RAP1A, RAP1B, CCND2
0.00294
Endocytosis
11 genes: VPS37A, ERBB4, RAB11FIP2, DNM3, KIT, PDGFRA, RAB4A, EEA1, USP8, RAB11B, ZFYVE16
0.003294
Calcium signaling pathway
10 genes: CHRM3, ERBB4, GRIN2A, MYLK, PDE1C, PDGFRA, PLCB4, PRKACB, BST1, CACNA1C
0.003708
MAPK signaling pathway
13 genes: FGF2, FGF7, FGF12, FGF13, MEF2C, PDGFRA, PPM1A, PRKACB, RAP1A, RAP1B, CACNA1C, CACNB2, MAP4K3
0.003808
Gastric acid secretion
6 genes: CHRM3, SLC26A7, KCNJ16, MYLK, PLCB4, PRKACB
0.004149
Regulation of actin cytoskeleton
11 genes: CFL2, CHRM3, DOCK1, FGF2, FGF7, FGF12, FGF13, MYLK, PPP1R12A, PDGFRA, PPP1CC
0.004896
Hedgehog signaling pathway
5 genes: RAB23, PRKACB, PTCH1, HHIP, SMO
0.005785
PI3K AKT signaling pathway
15 genes: FGF2, FGF7, FGF12, FGF13, IGF1, HGF, INSR, PDGFRA, KIT, COL4A4, COL9A1, LPAR1, PRKAA2, CCND2, FOXO3
0.006318
Vascular smooth muscle contraction
7 genes: MYLK, PPP1R12A, PLCB4, PPP1CC, PRKACB, PRKCE, CACNA1C
0.01011
Nicotinate and nicotinamide metabolism
3 genes: ENPP1, BST1, NUDT12
0.01266
Wnt signaling pathway
8 genes: NFAT5, PRICKLE2, SMAD4, PLCB4, PRKACB, FZD3, FZD4, CCND2
0.01296
Hippo signaling pathway
8 genes: AMOT, PPP1CC, TEAD1, SMAD4, BMPR2, FZD3, FZD4, CCND2
0.01445
Melanogenesis
6 genes: KIT, MITF, PLCB4, PRKACB, FZD3, FZD4
0.01795
Insulin signaling pathway
7 genes: FOXO1, INSR, PPP1CC, PRKAA2, PRKAB2, PRKACB, PRKAR2B
0.02407
TGF.beta signaling pathway
5 genes: INHBB, SMAD4, SMAD9, BMPR2, ZFYVE16
0.03079