Enriched cancer pathwayGenes under regulationP value
MAPK signaling pathway
17 genes: RASGRP1, MAP3K2, CRK, DUSP1, MRAS, MEF2C, MAP3K3, MYC, NGF, PDGFB, PPP3CA, MAPK9, TAOK1, RPS6KA3, TGFBR1, CACNB4, MAP4K4
3.825e-07
Focal adhesion
14 genes: COL1A1, COL1A2, COL3A1, COL4A1, COL4A2, COL4A5, COL5A2, CRK, FN1, IGF1R, ITGB3, PDGFB, MAPK9, CCND2
1.297e-06
ECM.receptor interaction
9 genes: COL1A1, COL1A2, COL3A1, COL4A1, COL4A2, COL4A5, COL5A2, FN1, ITGB3
3.716e-06
PI3K AKT signaling pathway
17 genes: NGF, PDGFB, IGF1R, GHR, OSMR, IL6R, COL1A1, COL1A2, COL4A2, COL4A1, COL4A5, FN1, ITGB3, PRKAA2, MYC, CDKN1A, CCND2
1.46e-05
Protein digestion and absorption
8 genes: COL1A1, COL1A2, COL3A1, COL4A1, COL4A2, COL4A5, COL5A2, COL15A1
2.172e-05
Neurotrophin signaling pathway
9 genes: SH2B3, CRK, MAP3K3, NGF, NTRK3, MAPK9, RPS6KA3, CALM1, IRS2
9.453e-05
Calcium signaling pathway
10 genes: ADCY9, ADRB2, ADRB3, GNAL, SLC25A4, ATP2B4, PLCB4, PPP3CA, PTAFR, CALM1
0.0002549
Insulin signaling pathway
8 genes: PPARGC1A, SOCS4, CRK, PRKAA2, MAPK9, CALM1, IRS2, CBL
0.0008857
Oocyte meiosis
7 genes: ADCY9, IGF1R, PPP3CA, RPS6KA3, CPEB1, CALM1, SMC1A
0.001323
ErbB signaling pathway
6 genes: CDKN1A, CRK, ABL2, MYC, MAPK9, CBL
0.001611
Salivary secretion
6 genes: ADCY9, ADRB2, ADRB3, ATP2B4, PLCB4, CALM1
0.00181
Jak.STAT signaling pathway
8 genes: SOCS4, GHR, IL6R, IL10, MYC, CBL, CCND2, OSMR
0.001863
Adipocytokine signaling pathway
5 genes: PPARGC1A, PRKAA2, MAPK9, ADIPOR2, IRS2
0.002975
GnRH signaling pathway
6 genes: MAP3K2, ADCY9, MAP3K3, PLCB4, MAPK9, CALM1
0.003422
Ras signaling pathway
9 genes: NGF, PDGFB, IGF1R, RASGRP1, CALM1, MRAS, RALB, MAPK9, ABL2
0.007405
TGF.beta signaling pathway
5 genes: DCN, GDF6, MYC, TGFBR1, CHRD
0.007688
Progesterone.mediated oocyte maturation
5 genes: ADCY9, IGF1R, MAPK9, RPS6KA3, CPEB1
0.008463
Long.term potentiation
4 genes: PLCB4, PPP3CA, RPS6KA3, CALM1
0.01838
T cell receptor signaling pathway
5 genes: RASGRP1, IL10, PPP3CA, MAPK9, CBL
0.02006
Vascular smooth muscle contraction
5 genes: ADCY9, PPP1R12B, PLCB4, CALD1, CALM1
0.02634
Endocytosis
7 genes: ADRB2, ADRB3, IGF1R, ASAP1, SMAP2, TGFBR1, CBL
0.02804
Cell cycle
5 genes: CDKN1A, MYC, RB1, SMC1A, CCND2
0.0379
mTOR signaling pathway
3 genes: PRKAA2, RPS6KA3, ULK2
0.03893
Glycosaminoglycan biosynthesis . chondroitin sulfate
2 genes: CHSY3, XYLT1
0.0395
Axon guidance
5 genes: EPHA3, EPHA7, PLXNA2, SEMA4C, PPP3CA
0.04009
Gap junction
4 genes: MAP3K2, ADCY9, PDGFB, PLCB4
0.04109