Enriched cancer pathwayGenes under regulationP value
Hippo signaling pathway
10 genes: WTIP, SAV1, LATS2, LATS1, DLG4, TEAD1, SMAD7, WNT7A, YWHAH, AXIN2
4.187e-05
PI3K AKT signaling pathway
12 genes: FGF2, FGF18, BDNF, ITGA2, PIK3R1, EIF4B, PTEN, PPP2R3C, CDK6, FOXO3, YWHAH, BCL2
0.002715
Circadian rhythm . mammal
3 genes: RORA, BHLHE40, CLOCK
0.003383
Focal adhesion
8 genes: ITGA2, ARHGAP5, PIK3R1, PTEN, BCL2, VCL, ZYX, CAV1
0.00544
Sphingolipid metabolism
3 genes: SGMS2, CERK, SMPD1
0.016
Endocytosis
7 genes: EHD1, AP2A1, RAB11FIP2, SMAD7, PLD1, RET, CAV1
0.01918
Phosphatidylinositol signaling system
4 genes: ITPR1, PIK3R1, PTEN, IPPK
0.02026
Vasopressin.regulated water reabsorption
3 genes: DYNC1I1, DYNC1LI2, DCTN5
0.02063
Notch signaling pathway
3 genes: DLL1, NOTCH2, NUMB
0.02454
Neurotrophin signaling pathway
5 genes: FOXO3, PIK3R1, BCL2, BDNF, YWHAH
0.02751
mTOR signaling pathway
3 genes: EIF4B, CAB39, PIK3R1
0.03188
Glycosaminoglycan biosynthesis . chondroitin sulfate
2 genes: CHST11, CHST7
0.03418
Cell adhesion molecules .CAMs.
5 genes: VCAN, NFASC, CD274, CNTNAP1, CD80
0.03544
Ras signaling pathway
7 genes: FGF2, FGF18, BDNF, PIK3R1, SHOC2, PLD1, ABL2
0.03894