| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Hippo signaling pathway |
14 genes: WTIP, FRMD6, DLG2, FBXW11, TEAD1, TGFBR2, SMAD7, BMP2, BMP7, BMPR2, TCF7L1, MYC, CCND1, CCND2
|
6.754e-06 |
| Osteoclast differentiation |
11 genes: AKT3, SIRPA, CSF1, CTSK, FHL2, FYN, JAK1, PIK3R1, PPP3CA, TGFBR2, SQSTM1
|
0.0001084 |
| PI3K AKT signaling pathway |
19 genes: CSF1, FGFR1, PDGFRA, IL6R, JAK1, COL1A1, THBS2, PIK3R1, AKT3, PTEN, PPP2R3A, MYC, CCND1, CDKN1A, CDK6, CCND2, CREB3L2, CREB5, MCL1
|
0.0002541 |
| Jak.STAT signaling pathway |
11 genes: AKT3, SPRED1, IL6R, IL10, JAK1, LIF, MYC, PIK3R1, CCND1, STAT3, CCND2
|
0.0005731 |
| p53 signaling pathway |
7 genes: CDK6, CDKN1A, FAS, PTEN, CCND1, ZMAT3, CCND2
|
0.0007212 |
| Circadian rhythm . mammal |
4 genes: CRY2, FBXW11, RORA, PER2
|
0.001384 |
| MAPK signaling pathway |
14 genes: AKT3, MAP3K2, MAP3K8, DUSP8, FGFR1, FAS, MAP3K3, MYC, TAOK3, PDGFRA, PPP3CA, RASGRF2, TGFBR2, MAP3K12
|
0.002227 |
| TGF.beta signaling pathway |
7 genes: SMAD7, MYC, BMP2, BMP7, BMPR2, TGFBR2, THBS2
|
0.002457 |
| Axon guidance |
8 genes: SEMA4B, NFAT5, CFL2, DPYSL2, EPHA7, FYN, PPP3CA, NTN1
|
0.007415 |
| T cell receptor signaling pathway |
7 genes: AKT3, NFAT5, MAP3K8, FYN, IL10, PIK3R1, PPP3CA
|
0.009112 |
| Sphingolipid metabolism |
4 genes: KDSR, SGMS1, ACER3, CERK
|
0.01071 |
| Focal adhesion |
10 genes: AKT3, COL1A1, FYN, ARHGAP5, PDGFRA, PIK3R1, PTEN, CCND1, THBS2, CCND2
|
0.01208 |
| Apoptosis |
6 genes: AKT3, FAS, IL1RAP, PIK3R1, PPP3CA, PRKAR2A
|
0.01279 |
| Vasopressin.regulated water reabsorption |
4 genes: ADCY9, DYNC1LI2, CREB3L2, CREB5
|
0.01487 |
| Adipocytokine signaling pathway |
5 genes: AKT3, CPT1A, SLC2A4, STAT3, TNFRSF1B
|
0.01589 |
| ErbB signaling pathway |
5 genes: AKT3, CDKN1A, ABL2, MYC, PIK3R1
|
0.04055 |
| Glycosphingolipid biosynthesis . ganglio series |
2 genes: ST6GALNAC3, ST6GALNAC6
|
0.04077 |
| Pantothenate and CoA biosynthesis |
2 genes: DPYD, ENPP1
|
0.04594 |
| Wnt signaling pathway |
7 genes: NFAT5, FBXW11, MYC, PPP3CA, CCND1, TCF7L1, CCND2
|
0.04637 |
| Lysosome |
6 genes: CTSK, GM2A, LAMP2, ARSB, CTSA, LAPTM4A
|
0.04802 |