| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Circadian rhythm . mammal |
6 genes: CRY2, FBXW11, FBXL3, RORA, PER2, CLOCK
|
7.557e-05 |
| Osteoclast differentiation |
14 genes: AKT3, IRF9, CSF1, CTSK, FHL2, FYN, JAK1, PIK3R1, PPP3CA, MAPK9, TGFBR2, CAMK4, SQSTM1, MAP3K14
|
7.934e-05 |
| Adipocytokine signaling pathway |
9 genes: AKT3, CPT1A, ACSL4, PPARA, PRKAA2, MAPK9, SLC2A4, STAT3, TNFRSF1B
|
0.0003602 |
| Hippo signaling pathway |
14 genes: WTIP, FRMD6, PPP2R2A, FBXW11, TEAD1, TGFBR2, SMAD7, BMPR2, FZD7, FZD4, APC, TCF7L1, CCND1, CCND2
|
0.0005522 |
| MAPK signaling pathway |
20 genes: AKT3, MAP3K2, MAP3K8, CRK, DUSP8, FGFR1, RRAS2, MAP3K3, TAOK3, PDGFRA, PPM1A, PPP3CA, MAPK9, RASGRF2, RPS6KA3, TGFBR2, MAP3K12, MAP3K14, RPS6KA5, RAPGEF2
|
0.0005623 |
| PI3K AKT signaling pathway |
24 genes: CSF1, FGFR1, PDGFRA, TLR2, PIK3AP1, IL6R, JAK1, COL1A1, COL4A3, THBS2, ITGB8, PIK3R1, PRKAA2, AKT3, PTEN, PPP2R2A, PPP2R3A, CCND1, CDKN1A, CDK6, CCND2, CREB3L2, CREB5, MCL1
|
0.000592 |
| Focal adhesion |
15 genes: AKT3, COL1A1, CRK, FYN, ITGB8, PDGFRA, PIK3R1, MAPK9, PTEN, CCND1, THBS2, VASP, CAV1, CAV2, CCND2
|
0.002516 |
| Neurotrophin signaling pathway |
11 genes: AKT3, SH2B3, CRK, GAB1, MAP3K3, NTRK3, PIK3R1, MAPK9, RPS6KA3, CAMK4, RPS6KA5
|
0.003069 |
| p53 signaling pathway |
7 genes: CDK6, CDKN1A, SESN3, PTEN, CCND1, ZMAT3, CCND2
|
0.007287 |
| Endocytosis |
13 genes: CLTC, DAB2, RAB11FIP5, LDLR, SMAD7, ASAP1, PDGFRA, PSD, TGFBR2, EEA1, CAV1, CAV2, RABEP1
|
0.01658 |
| ErbB signaling pathway |
7 genes: AKT3, CDKN1A, CRK, GAB1, ABL2, PIK3R1, MAPK9
|
0.02397 |
| T cell receptor signaling pathway |
8 genes: AKT3, MAP3K8, FYN, PIK3R1, PPP3CA, MAPK9, MAP3K14, CD28
|
0.02556 |
| Wnt signaling pathway |
10 genes: FBXW11, APC, PPP3CA, MAPK9, CCND1, TBL1X, FZD4, FZD7, TCF7L1, CCND2
|
0.02707 |
| mTOR signaling pathway |
5 genes: AKT3, HIF1A, PIK3R1, PRKAA2, RPS6KA3
|
0.0272 |
| Jak.STAT signaling pathway |
10 genes: AKT3, IRF9, SPRED1, IL6R, JAK1, LIF, PIK3R1, CCND1, STAT3, CCND2
|
0.03163 |
| Fc gamma R.mediated phagocytosis |
7 genes: AKT3, WASF2, CFL2, CRK, ASAP1, PIK3R1, VASP
|
0.03638 |
| Insulin signaling pathway |
9 genes: AKT3, CRK, PIK3R1, PRKAA2, PRKAR2A, MAPK9, SLC2A4, PPP1R3B, TRIP10
|
0.03792 |
| Sphingolipid metabolism |
4 genes: KDSR, SGMS1, ACER3, CERK
|
0.04109 |