Enriched cancer pathwayGenes under regulationP value
Hematopoietic cell lineage
11 genes: CR1, CSF2RA, FCER2, ITGA5, KIT, TPO, CD1D, CD4, CD7, CD34, CD37
5.5e-06
Calcium signaling pathway
14 genes: AGTR1, GNAL, ITPKB, ITPR1, ATP2A3, ATP2B4, P2RX7, PDGFRA, PLCB2, PTGER3, PTGFR, BDKRB1, SLC8A1, TACR1
6.297e-05
Cell adhesion molecules .CAMs.
12 genes: CDH5, CNTN1, NFASC, HLA-DQA1, JAM2, SELP, SIGLEC1, SPN, CD4, NRXN3, NRXN1, CD34
7.333e-05
Phosphatidylinositol signaling system
7 genes: DGKB, DGKG, PIK3R5, ITPK1, ITPKB, ITPR1, PLCB2
0.002107
Protein digestion and absorption
7 genes: KCNE3, COL4A4, CPA3, FXYD2, SLC8A1, XPNPEP2, COL18A1
0.002616
Tryptophan metabolism
5 genes: INMT, ALDH3A2, HAAO, IDO1, OGDH
0.002658
Aldosterone.regulated sodium reabsorption
4 genes: PIK3R5, NR3C2, FXYD2, SGK1
0.01552
Vascular smooth muscle contraction
7 genes: RAMP3, AGTR1, ITPR1, PPP1R12B, NPR1, PLCB2, CALD1
0.01778
Lysine degradation
4 genes: ALDH3A2, OGDH, PIPOX, SETD7
0.01816
Long.term depression
5 genes: GNAO1, GNAZ, GRIA3, ITPR1, PLCB2
0.02247
Osteoclast differentiation
7 genes: LILRB4, FCGR2B, PIK3R5, FYN, MITF, MAPK9, FCGR2C
0.02863
Pancreatic secretion
6 genes: CPA3, ITPR1, FXYD2, ATP2A3, ATP2B4, PLCB2
0.02916
Axon guidance
7 genes: CFL2, DPYSL2, EPHA3, FYN, SLIT3, SEMA6D, ABLIM2
0.0308
Cardiac muscle contraction
5 genes: FXYD2, SLC8A1, TPM1, TPM2, CACNB2
0.03225
Antigen processing and presentation
5 genes: CTSB, HLA-DQA1, CIITA, CD4, CD74
0.03384
Glycine. serine and threonine metabolism
3 genes: AMT, DMGDH, PIPOX
0.03662