| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Hematopoietic cell lineage |
11 genes: CR1, CSF2RA, FCER2, ITGA5, KIT, TPO, CD1D, CD4, CD7, CD34, CD37
|
5.5e-06 |
| Calcium signaling pathway |
14 genes: AGTR1, GNAL, ITPKB, ITPR1, ATP2A3, ATP2B4, P2RX7, PDGFRA, PLCB2, PTGER3, PTGFR, BDKRB1, SLC8A1, TACR1
|
6.297e-05 |
| Cell adhesion molecules .CAMs. |
12 genes: CDH5, CNTN1, NFASC, HLA-DQA1, JAM2, SELP, SIGLEC1, SPN, CD4, NRXN3, NRXN1, CD34
|
7.333e-05 |
| Phosphatidylinositol signaling system |
7 genes: DGKB, DGKG, PIK3R5, ITPK1, ITPKB, ITPR1, PLCB2
|
0.002107 |
| Protein digestion and absorption |
7 genes: KCNE3, COL4A4, CPA3, FXYD2, SLC8A1, XPNPEP2, COL18A1
|
0.002616 |
| Tryptophan metabolism |
5 genes: INMT, ALDH3A2, HAAO, IDO1, OGDH
|
0.002658 |
| Aldosterone.regulated sodium reabsorption |
4 genes: PIK3R5, NR3C2, FXYD2, SGK1
|
0.01552 |
| Vascular smooth muscle contraction |
7 genes: RAMP3, AGTR1, ITPR1, PPP1R12B, NPR1, PLCB2, CALD1
|
0.01778 |
| Lysine degradation |
4 genes: ALDH3A2, OGDH, PIPOX, SETD7
|
0.01816 |
| Long.term depression |
5 genes: GNAO1, GNAZ, GRIA3, ITPR1, PLCB2
|
0.02247 |
| Osteoclast differentiation |
7 genes: LILRB4, FCGR2B, PIK3R5, FYN, MITF, MAPK9, FCGR2C
|
0.02863 |
| Pancreatic secretion |
6 genes: CPA3, ITPR1, FXYD2, ATP2A3, ATP2B4, PLCB2
|
0.02916 |
| Axon guidance |
7 genes: CFL2, DPYSL2, EPHA3, FYN, SLIT3, SEMA6D, ABLIM2
|
0.0308 |
| Cardiac muscle contraction |
5 genes: FXYD2, SLC8A1, TPM1, TPM2, CACNB2
|
0.03225 |
| Antigen processing and presentation |
5 genes: CTSB, HLA-DQA1, CIITA, CD4, CD74
|
0.03384 |
| Glycine. serine and threonine metabolism |
3 genes: AMT, DMGDH, PIPOX
|
0.03662 |