| Enriched cancer pathway | Genes under regulation | P value |
|---|
| PI3K AKT signaling pathway |
28 genes: FGF1, FGF2, FGF7, FGF5, CSF1, KITLG, HGF, FGFR2, NTRK2, SOS1, IL7, GHR, COL1A1, LAMC1, TNC, ITGA1, PIK3CA, CHRM2, GNG12, PRKAA2, SGK3, PPP2R2B, PPP2R5E, PHLPP2, FOXO3, BCL2, CREB1, ATF2
|
3.901e-07 |
| Regulation of actin cytoskeleton |
21 genes: ABI2, CFL2, CHRM2, CHRM3, FGF1, FGF2, FGF5, FGF7, FGFR2, ARHGEF12, TIAM2, ITGA1, MYLK, PIK3CA, PIP4K2A, SSH1, PPP1CB, GNG12, ROCK1, SOS1, ROCK2
|
4.04e-07 |
| Hippo signaling pathway |
14 genes: MPP5, YAP1, WWTR1, SAV1, PPP2R2B, LATS1, PPP1CB, TEAD1, FGF1, TGFB2, TGFBR1, SMAD4, BMPR2, SNAI2
|
7.969e-05 |
| Calcium signaling pathway |
14 genes: CHRM2, CHRM3, EDNRA, GNAL, GNAQ, GRIN2A, MYLK, PDE1A, PDE1C, PHKA1, PHKB, PRKACB, PTGER3, PTGFR
|
0.0003446 |
| Focal adhesion |
15 genes: COL1A1, COL5A2, COL11A1, HGF, TNC, ITGA1, LAMC1, ARHGAP5, MYLK, PIK3CA, PPP1CB, BCL2, ROCK1, SOS1, ROCK2
|
0.0003799 |
| Insulin signaling pathway |
12 genes: PPARGC1A, FOXO1, PHKA1, PHKB, PIK3CA, PPP1CB, PRKAA2, PRKAB2, PRKACB, SOS1, PPP1R3B, IRS2
|
0.0003829 |
| MAPK signaling pathway |
18 genes: MAP3K2, ATF2, DUSP3, FGF1, FGF2, FGF5, FGF7, FGFR2, NTRK2, PPM1A, PRKACB, GNG12, SOS1, TGFB2, TGFBR1, MAP3K12, CACNA2D1, CACNB4
|
0.0004002 |
| TGF.beta signaling pathway |
9 genes: CREBBP, INHBA, SMAD4, SMAD9, ROCK1, BMPR2, TGFB2, TGFBR1, ROCK2
|
0.000488 |
| Vascular smooth muscle contraction |
10 genes: EDNRA, ARHGEF12, GNAQ, MYLK, PPP1CB, PRKACB, PRKG1, ROCK1, CALD1, ROCK2
|
0.00123 |
| Ras signaling pathway |
15 genes: FGF1, FGF2, FGF7, FGF5, CSF1, KITLG, HGF, FGFR2, NTRK2, GAB1, SOS1, GNG12, PRKACB, GRIN2A, PIK3CA
|
0.002042 |
| Axon guidance |
10 genes: SEMA3A, SEMA3C, CFL2, EPHA7, NTNG1, ARHGEF12, ABLIM1, ROCK1, SLIT2, ROCK2
|
0.002874 |
| ECM.receptor interaction |
7 genes: COL1A1, COL5A2, COL11A1, TNC, ITGA1, LAMC1, CD47
|
0.008261 |
| Adherens junction |
6 genes: SSX2IP, CREBBP, FER, SMAD4, SNAI2, TGFBR1
|
0.01419 |
| Neurotrophin signaling pathway |
8 genes: FOXO3, GAB1, NTRK2, PIK3CA, KIDINS220, BCL2, SOS1, IRS2
|
0.02241 |
| Adipocytokine signaling pathway |
5 genes: PPARGC1A, LEPR, PRKAA2, PRKAB2, IRS2
|
0.03706 |
| Long.term potentiation |
5 genes: CREBBP, GNAQ, GRIN2A, PPP1CB, PRKACB
|
0.04121 |