| Enriched cancer pathway | Genes under regulation | P value |
|---|
| TGF.beta signaling pathway |
10 genes: INHBB, SMAD4, SMAD5, MAPK1, SKP1, BMPR2, TGFBR2, ACVR1, ACVR2A, ZFYVE9
|
4.174e-06 |
| Endocytosis |
14 genes: CLTC, VPS37A, DNM2, DNM3, KIT, PDGFRA, PSD, RAB5A, RAB5B, SRC, TGFBR2, RAB11FIP1, PARD6G, ZFYVE9
|
3.019e-05 |
| Gap junction |
9 genes: ADCY2, PLCB1, GJA1, ITPR1, PDGFRA, PRKG1, MAPK1, SOS2, SRC
|
4.726e-05 |
| Oocyte meiosis |
10 genes: ADCY2, FBXW11, IGF1, AR, ITPR1, PGR, MAPK1, CPEB1, SKP1, BTRC
|
5.622e-05 |
| Hippo signaling pathway |
11 genes: PARD6G, FRMD6, RASSF6, DLG2, BTRC, FBXW11, TEAD1, TGFBR2, SMAD4, BMPR2, WNT2B
|
0.0001562 |
| Phosphatidylinositol signaling system |
7 genes: PLCB1, ITPR1, OCRL, PIK3C2A, PIK3CB, PTEN, DGKE
|
0.0006391 |
| Circadian rhythm . mammal |
4 genes: FBXW11, SKP1, BHLHE41, BTRC
|
0.0008041 |
| Progesterone.mediated oocyte maturation |
7 genes: ADCY2, IGF1, PGR, PIK3CB, MAPK1, MAPK10, CPEB1
|
0.001225 |
| Adherens junction |
6 genes: SMAD4, MAPK1, PTPRM, SRC, TGFBR2, WASL
|
0.002438 |
| GnRH signaling pathway |
7 genes: ADCY2, PLCB1, ITPR1, MAPK1, MAPK10, SOS2, SRC
|
0.002889 |
| Inositol phosphate metabolism |
5 genes: PLCB1, OCRL, PIK3C2A, PIK3CB, PTEN
|
0.004203 |
| Focal adhesion |
10 genes: LAMC3, IGF1, PDGFRA, PIK3CB, MAPK1, MAPK10, PTEN, SOS2, SRC, ITGA8
|
0.004533 |
| Ubiquitin mediated proteolysis |
8 genes: FBXW11, MGRN1, BIRC6, SKP1, CUL3, HERC3, BTRC, UBE3B
|
0.00468 |
| Vascular smooth muscle contraction |
7 genes: ADCY2, PLCB1, ARHGEF12, ITPR1, PPP1R12B, PRKG1, MAPK1
|
0.006183 |
| Wnt signaling pathway |
8 genes: DAAM1, PLCB1, FBXW11, SMAD4, MAPK10, SKP1, WNT2B, BTRC
|
0.007623 |
| Fc gamma R.mediated phagocytosis |
6 genes: CFL2, DNM2, DNM3, PIK3CB, MAPK1, WASL
|
0.008853 |
| Vasopressin.regulated water reabsorption |
4 genes: DYNLL2, DYNC1LI2, RAB5A, RAB5B
|
0.009063 |
| Long.term depression |
5 genes: PLCB1, IGF1, ITPR1, PRKG1, MAPK1
|
0.009984 |
| Dorso.ventral axis formation |
3 genes: MAPK1, CPEB1, SOS2
|
0.011 |
| Ras signaling pathway |
10 genes: IGF1, IGF2, PDGFRA, KIT, SOS2, PIK3CB, MAPK1, MAPK10, RAB5A, RAB5B
|
0.01372 |
| PI3K AKT signaling pathway |
13 genes: IGF1, IGF2, PDGFRA, KIT, SOS2, MAPK1, IL6R, LAMC3, ITGA8, PIK3CB, PRKAA1, PTEN, FOXO3
|
0.01538 |
| mTOR signaling pathway |
4 genes: IGF1, PIK3CB, PRKAA1, MAPK1
|
0.0161 |
| Regulation of actin cytoskeleton |
9 genes: ABI2, CFL2, ARHGEF12, PDGFRA, PIK3CB, MAPK1, SOS2, ITGA8, WASL
|
0.01969 |
| Hedgehog signaling pathway |
4 genes: FBXW11, SUFU, WNT2B, BTRC
|
0.02061 |
| ErbB signaling pathway |
5 genes: PIK3CB, MAPK1, MAPK10, SOS2, SRC
|
0.02363 |
| Glycosphingolipid biosynthesis . ganglio series |
2 genes: ST6GALNAC3, ST3GAL1
|
0.03118 |
| Neurotrophin signaling pathway |
6 genes: FOXO3, PIK3CB, MAPK1, MAPK10, SOS2, RPS6KA5
|
0.03226 |
| Adipocytokine signaling pathway |
4 genes: PPARGC1A, ACSL1, PRKAA1, MAPK10
|
0.03847 |
| p53 signaling pathway |
4 genes: SESN3, IGF1, PTEN, ZMAT3
|
0.04026 |
| Melanogenesis |
5 genes: ADCY2, PLCB1, KIT, MAPK1, WNT2B
|
0.04115 |
| Aldosterone.regulated sodium reabsorption |
3 genes: IGF1, PIK3CB, MAPK1
|
0.04355 |
| Insulin signaling pathway |
6 genes: PPARGC1A, PIK3CB, PRKAA1, MAPK1, MAPK10, SOS2
|
0.04538 |
| Fatty acid metabolism |
3 genes: ACSL1, HADHA, HADHB
|
0.04619 |