Enriched cancer pathwayGenes under regulationP value
Neurotrophin signaling pathway
11 genes: MAPK14, PIK3R5, RAPGEF1, RHOA, NTRK2, NTRK3, PIK3R1, KIDINS220, SORT1, CAMK2A, CAMK2D
4.407e-06
Wnt signaling pathway
9 genes: RHOA, NFATC2, NFATC3, TBL1X, WNT5B, CAMK2A, CAMK2D, FZD4, CCND2
0.0005667
Axon guidance
8 genes: SEMA3D, RHOA, NFATC2, NFATC3, PLXNA2, ROBO2, SEMA6D, UNC5C
0.0009252
Melanogenesis
7 genes: GNAO1, KITLG, CREB3L2, WNT5B, CAMK2A, CAMK2D, FZD4
0.0009597
Glycosaminoglycan biosynthesis . chondroitin sulfate
3 genes: CHST11, XYLT1, CHST3
0.004483
VEGF signaling pathway
5 genes: MAPK14, PIK3R5, NFATC2, NFATC3, PIK3R1
0.006356
T cell receptor signaling pathway
6 genes: MAPK14, PIK3R5, RHOA, NFATC2, NFATC3, PIK3R1
0.00655
ErbB signaling pathway
5 genes: PIK3R5, PIK3R1, STAT5A, CAMK2A, CAMK2D
0.0111
Focal adhesion
8 genes: PIK3R5, RAPGEF1, IGF1R, ITGB3, RHOA, PIK3R1, ACTN4, CCND2
0.01256
Osteoclast differentiation
6 genes: MAPK14, CTSK, PIK3R5, ITGB3, NFATC2, PIK3R1
0.01442
Insulin signaling pathway
6 genes: PIK3R5, GCK, RAPGEF1, PIK3R1, PRKAB2, PPP1R3B
0.02015
PI3K AKT signaling pathway
11 genes: KITLG, NTRK2, IGF1R, ITGB3, PIK3R1, PIK3R5, EIF4B, PHLPP2, CDK6, CCND2, CREB3L2
0.02069
Adherens junction
4 genes: IGF1R, RHOA, TJP1, ACTN4
0.02619
B cell receptor signaling pathway
4 genes: PIK3R5, NFATC2, NFATC3, PIK3R1
0.02857
Cardiac muscle contraction
4 genes: ATP2A2, RYR2, SLC8A1, TPM2
0.03107
Hippo signaling pathway
6 genes: DLG2, TEAD1, BMPR2, WNT5B, FZD4, CCND2
0.03222
Jak.STAT signaling pathway
6 genes: CTF1, PIK3R5, IL13RA1, PIK3R1, STAT5A, CCND2
0.03311
Leukocyte transendothelial migration
5 genes: MAPK14, PIK3R5, RHOA, PIK3R1, ACTN4
0.03484
ECM.receptor interaction
4 genes: ITGB3, CD44, SDC3, SV2B
0.04231
Progesterone.mediated oocyte maturation
4 genes: MAPK14, PIK3R5, IGF1R, PIK3R1
0.04544
mTOR signaling pathway
3 genes: EIF4B, PIK3R5, PIK3R1
0.04597
Hematopoietic cell lineage
4 genes: CR1, ITGB3, KITLG, CD44
0.04705
Regulation of actin cytoskeleton
7 genes: PIK3R5, CYFIP2, ITGB3, RHOA, PIK3R1, ACTN4, ARHGEF6
0.04835
Nitrogen metabolism
2 genes: CA14, GLUL
0.04836
Circadian rhythm . mammal
2 genes: RORA, NR1D1
0.04836