| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Circadian rhythm . mammal |
4 genes: RORA, BHLHE41, PER3, BTRC
|
5.702e-05 |
| Focal adhesion |
7 genes: FLNA, PIP5K1C, LAMC1, MYLK, PRKCA, PTEN, SOS2
|
0.00281 |
| One carbon pool by folate |
2 genes: MTHFR, MTR
|
0.01206 |
| Melanogenesis |
4 genes: EP300, GNAO1, KIT, PRKCA
|
0.01496 |
| PI3K AKT signaling pathway |
8 genes: KIT, SOS2, IL6R, LAMC1, EIF4B, PRKCA, PTEN, CASP9
|
0.01771 |
| Dorso.ventral axis formation |
2 genes: ETS1, SOS2
|
0.02265 |
| Ras signaling pathway |
6 genes: KIT, PTPN11, SOS2, RASSF5, ETS1, PRKCA
|
0.02382 |
| p53 signaling pathway |
3 genes: PTEN, ZMAT3, CASP9
|
0.02686 |
| Lysine biosynthesis |
1 genes: ALDH7A1
|
0.02779 |
| Long.term potentiation |
3 genes: EP300, PRKCA, RPS6KA2
|
0.02788 |
| Neurotrophin signaling pathway |
4 genes: MAP3K3, PTPN11, RPS6KA2, SOS2
|
0.03148 |
| Axon guidance |
4 genes: PLXNC1, UNC5B, ARHGEF12, PLXNA2
|
0.03387 |
| Tight junction |
4 genes: PRKCA, ASH1L, PTEN, TJP2
|
0.03637 |
| Phosphatidylinositol signaling system |
3 genes: PIP5K1C, PRKCA, PTEN
|
0.03672 |
| MAPK signaling pathway |
6 genes: FLNA, HSPA1L, MAP3K3, PRKCA, RPS6KA2, SOS2
|
0.0405 |
| Endocytosis |
5 genes: ERBB4, PIP5K1C, HSPA1L, KIT, SMAD3
|
0.04226 |
| Cysteine and methionine metabolism |
2 genes: MAT2A, MTR
|
0.04451 |
| ErbB signaling pathway |
3 genes: ERBB4, PRKCA, SOS2
|
0.04818 |