| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Ras signaling pathway |
17 genes: HGF, EGFR, PDGFRA, GAB1, GAB2, SHC1, GNG4, GNG7, PRKACB, CALM1, RASA4, RASAL2, ETS1, KSR1, RAPGEF5, ABL1, ABL2
|
5.5e-06 |
| Neurotrophin signaling pathway |
12 genes: SH2B3, IRAK3, MAPK14, ABL1, GAB1, JUN, MAP3K3, NTRK3, SHC1, CALM1, CAMK4, IRS2
|
8.971e-06 |
| ErbB signaling pathway |
9 genes: EGFR, ABL1, GAB1, ABL2, JUN, SHC1, STAT5A, STAT5B, CBL
|
5.833e-05 |
| Cell adhesion molecules .CAMs. |
11 genes: CNTN1, VCAN, NFASC, CD274, ITGAV, ITGB8, SDC2, SIGLEC1, SPN, VCAM1, NRXN1
|
8.895e-05 |
| Focal adhesion |
12 genes: COL11A1, CTNNB1, EGFR, HGF, ITGAV, ITGB8, JUN, PDGFRA, PTEN, SHC1, TLN2, CCND2
|
0.0006973 |
| GnRH signaling pathway |
8 genes: MAP3K2, MAPK14, EGFR, GNAQ, JUN, MAP3K3, PRKACB, CALM1
|
0.0009251 |
| Circadian rhythm . mammal |
4 genes: ARNTL, RORA, BHLHE40, CLOCK
|
0.001013 |
| Hippo signaling pathway |
10 genes: YAP1, WWTR1, WTIP, FRMD6, TEAD1, GLI2, TGFB2, CTNNB1, TCF7L1, CCND2
|
0.001053 |
| Jak.STAT signaling pathway |
9 genes: CSF3, SPRED1, IL6R, LIF, STAT4, STAT5A, STAT5B, CBL, CCND2
|
0.00393 |
| PI3K AKT signaling pathway |
15 genes: HGF, EGFR, PDGFRA, CSF3, IL6R, ITGAV, ITGB8, GNG4, GNG7, PRKAA2, PTEN, PHLPP2, CDK6, CCND2, CREB5
|
0.004737 |
| Insulin signaling pathway |
8 genes: PPARGC1A, FOXO1, PRKAA2, PRKACB, SHC1, CALM1, IRS2, CBL
|
0.006459 |
| ECM.receptor interaction |
6 genes: COL11A1, ITGAV, ITGB8, SDC2, CD47, SV2B
|
0.006987 |
| MAPK signaling pathway |
12 genes: MAP3K2, MAPK14, DUSP3, EGFR, GNA12, JUN, MAX, MAP3K3, PDGFRA, PRKACB, SRF, TGFB2
|
0.007706 |
| Adherens junction |
5 genes: WASF3, CTNNB1, EGFR, FER, TCF7L1
|
0.01514 |
| Gap junction |
5 genes: MAP3K2, EGFR, GNAQ, PDGFRA, PRKACB
|
0.03383 |
| Osteoclast differentiation |
6 genes: MAPK14, CYLD, JUN, TGFB2, CAMK4, GAB2
|
0.04299 |
| Axon guidance |
6 genes: PLXNC1, EPHA7, ABL1, CXCL12, UNC5C, NRP1
|
0.04577 |