| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Focal adhesion |
10 genes: COL4A4, COL5A1, COL5A2, HGF, IGF1, PPP1R12A, RAP1A, BCL2, CCND2, ROCK2
|
2.788e-05 |
| Cell adhesion molecules .CAMs. |
8 genes: VCAN, NLGN1, CADM1, CD274, NCAM1, NCAM2, NRXN1, CD28
|
5.741e-05 |
| Glycosaminoglycan biosynthesis . chondroitin sulfate |
3 genes: CHST11, XYLT1, CHST3
|
0.001226 |
| Protein digestion and absorption |
4 genes: COL4A4, COL5A1, COL5A2, ATP1A2
|
0.008131 |
| TGF.beta signaling pathway |
4 genes: FST, INHBA, LTBP1, ROCK2
|
0.009604 |
| ECM.receptor interaction |
4 genes: COL4A4, COL5A1, COL5A2, SV2B
|
0.009604 |
| Hippo signaling pathway |
5 genes: WWTR1, WTIP, DLG2, TEAD1, CCND2
|
0.01763 |
| PI3K AKT signaling pathway |
8 genes: IGF1, IGF2, HGF, NTRK2, IL2RA, COL4A4, CCND2, BCL2
|
0.02214 |
| Glycosphingolipid biosynthesis . lacto and neolacto series |
2 genes: FUT4, B3GALT2
|
0.02636 |
| Vascular smooth muscle contraction |
4 genes: ADCY9, PPP1R12A, PPP1R12B, ROCK2
|
0.02696 |
| Bile secretion |
3 genes: ADCY9, AQP9, ATP1A2
|
0.03216 |
| Gastric acid secretion |
3 genes: ADCY9, KCNK2, ATP1A2
|
0.03572 |
| Neurotrophin signaling pathway |
4 genes: IRAK3, NTRK2, RAP1A, BCL2
|
0.03588 |
| Axon guidance |
4 genes: DPYSL2, SLIT3, UNC5C, ROCK2
|
0.03857 |