| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Regulation of actin cytoskeleton |
15 genes: APC2, FGF1, ITGA3, ITGA5, ARAF, ITGB3, LIMK2, MSN, MYH10, ARHGEF4, PDGFRB, GNG12, RDX, BDKRB2, IQGAP1
|
0.0001728 |
| Hematopoietic cell lineage |
7 genes: CSF1, CSF3, IL6R, ITGA3, ITGA5, ITGB3, CD44
|
0.00468 |
| Pyrimidine metabolism |
7 genes: CANT1, DPYD, POLR1A, NT5E, POLA1, PRIM1, RRM1
|
0.008821 |
| PI3K AKT signaling pathway |
16 genes: FGF1, CSF1, PDGFRB, CSF3, IL6R, JAK1, ITGA3, ITGA5, ITGB3, GNG2, GNG12, PTEN, CDKN1A, FOXO3, YWHAZ, YWHAH
|
0.009243 |
| Lysine degradation |
4 genes: DLST, ALDH3A2, ACAT1, NSD1
|
0.01949 |
| MAPK signaling pathway |
12 genes: MAP3K2, RASGRP4, DUSP3, FGF1, MAX, MAP3K3, PDGFRB, CACNA2D3, GNG12, DUSP22, RAP1A, RPS6KA5
|
0.02524 |
| Phagosome |
8 genes: TLR6, CD209, HLA-DQB1, HLA-F, ITGA5, ITGB3, TAP1, MRC2
|
0.03133 |
| Melanogenesis |
6 genes: ADCY9, CTNNB1, GNAI1, GNAO1, WNT9A, WNT5B
|
0.03191 |
| Mucin type O.Glycan biosynthesis |
3 genes: GALNT6, GALNT10, GCNT3
|
0.03274 |
| Purine metabolism |
8 genes: ADA, ADCY9, CANT1, POLR1A, NT5E, POLA1, PRIM1, RRM1
|
0.03789 |
| mRNA surveillance pathway |
5 genes: PAPOLA, ETF1, NCBP1, PELO, CPSF2
|
0.04585 |
| Ubiquitin mediated proteolysis |
7 genes: HUWE1, UBA6, SMURF2, UBE2Z, UBE2A, UBE2D2, UBE3C
|
0.04609 |
| Focal adhesion |
9 genes: CTNNB1, ITGA3, ITGA5, ITGB3, PDGFRB, PTEN, RAP1A, CAV1, CAV2
|
0.04728 |
| ECM.receptor interaction |
5 genes: ITGA3, ITGA5, ITGB3, CD44, CD47
|
0.04991 |