Enriched cancer pathwayGenes under regulationP value
MAPK signaling pathway
14 genes: ATF2, ELK4, FGF2, FGF12, MAPT, NF1, NFATC2, NTRK2, PPM1A, PRKCA, TAOK1, CACNB2, CACNB4, PLA2G12A
0.006261
p53 signaling pathway
6 genes: SESN3, MDM4, ATM, SIAH1, PPM1D, CCNG2
0.006642
Ras signaling pathway
12 genes: FGF2, FGF12, NTRK2, FLT1, GRIN2A, NF1, TIAM1, PLA2G12A, KSR2, RALBP1, PRKCA, ABL1
0.01329
Axon guidance
8 genes: SEMA3C, EPHA3, EPHA4, ARHGEF12, ABL1, NFATC2, SEMA5A, SEMA3E
0.01434
Glycosaminoglycan biosynthesis . heparan sulfate
3 genes: B3GAT2, XYLT1, HS2ST1
0.02462
Endocytosis
10 genes: RNF41, AGAP1, RAB11FIP2, FLT1, ACAP2, DNM3, RAB11FIP1, EEA1, CBLB, RAB11FIP3
0.02741
Calcium signaling pathway
9 genes: ADCY2, EDNRB, GNAL, GRIN2A, ATP2B1, PDE1C, PRKCA, PTGFR, RYR2
0.02968
Jak.STAT signaling pathway
8 genes: SPRY3, GHR, IL6ST, LEPR, PRLR, TPO, TSLP, CBLB
0.03625