| Enriched cancer pathway | Genes under regulation | P value |
|---|
| MAPK signaling pathway |
14 genes: ATF2, ELK4, FGF2, FGF12, MAPT, NF1, NFATC2, NTRK2, PPM1A, PRKCA, TAOK1, CACNB2, CACNB4, PLA2G12A
|
0.006261 |
| p53 signaling pathway |
6 genes: SESN3, MDM4, ATM, SIAH1, PPM1D, CCNG2
|
0.006642 |
| Ras signaling pathway |
12 genes: FGF2, FGF12, NTRK2, FLT1, GRIN2A, NF1, TIAM1, PLA2G12A, KSR2, RALBP1, PRKCA, ABL1
|
0.01329 |
| Axon guidance |
8 genes: SEMA3C, EPHA3, EPHA4, ARHGEF12, ABL1, NFATC2, SEMA5A, SEMA3E
|
0.01434 |
| Glycosaminoglycan biosynthesis . heparan sulfate |
3 genes: B3GAT2, XYLT1, HS2ST1
|
0.02462 |
| Endocytosis |
10 genes: RNF41, AGAP1, RAB11FIP2, FLT1, ACAP2, DNM3, RAB11FIP1, EEA1, CBLB, RAB11FIP3
|
0.02741 |
| Calcium signaling pathway |
9 genes: ADCY2, EDNRB, GNAL, GRIN2A, ATP2B1, PDE1C, PRKCA, PTGFR, RYR2
|
0.02968 |
| Jak.STAT signaling pathway |
8 genes: SPRY3, GHR, IL6ST, LEPR, PRLR, TPO, TSLP, CBLB
|
0.03625 |