| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Gap junction |
9 genes: ADCY9, EGFR, GNAQ, GUCY1A2, PDGFB, PDGFRA, PRKCA, PRKCB, MAPK1
|
9.132e-07 |
| MAPK signaling pathway |
14 genes: AKT3, CHUK, EGFR, PDGFB, PDGFRA, PRKCA, PRKCB, MAPK1, TAOK1, RASGRF1, RPS6KA3, BDNF, STK3, TGFBR2
|
2.754e-06 |
| Ras signaling pathway |
13 genes: BDNF, PDGFB, EGFR, IGF1R, PDGFRA, GNB1, RASGRF1, AKT3, CHUK, MAPK1, PRKCA, PRKCB, ABL2
|
3.526e-06 |
| Calcium signaling pathway |
11 genes: ADCY9, EGFR, GNAQ, PDE1C, PDGFRA, PRKCA, PRKCB, RYR2, SLC8A1, CAMK4, CAMK2D
|
6.434e-06 |
| Long.term potentiation |
7 genes: GNAQ, PRKCA, PRKCB, MAPK1, RPS6KA3, CAMK4, CAMK2D
|
1.529e-05 |
| GnRH signaling pathway |
8 genes: ADCY9, EGFR, GNAQ, MMP14, PRKCA, PRKCB, MAPK1, CAMK2D
|
2.117e-05 |
| ErbB signaling pathway |
7 genes: AKT3, EGFR, ABL2, PRKCA, PRKCB, MAPK1, CAMK2D
|
6.323e-05 |
| Long.term depression |
6 genes: GNAQ, GUCY1A2, IGF1R, PRKCA, PRKCB, MAPK1
|
0.0001502 |
| PI3K AKT signaling pathway |
13 genes: BDNF, PDGFB, EGFR, IGF1R, PDGFRA, MAPK1, GNB1, PRKAA2, MTOR, PRKCA, AKT3, PPP2R5E, CHUK
|
0.0002166 |
| Focal adhesion |
9 genes: AKT3, EGFR, IGF1R, PDGFB, PDGFRA, PRKCA, PRKCB, MAPK1, RASGRF1
|
0.0005137 |
| Neurotrophin signaling pathway |
7 genes: AKT3, IRAK3, MAPK1, RPS6KA3, BDNF, CAMK4, CAMK2D
|
0.0006576 |
| Melanogenesis |
6 genes: ADCY9, GNAQ, PRKCA, PRKCB, MAPK1, CAMK2D
|
0.001082 |
| Gastric acid secretion |
5 genes: ADCY9, GNAQ, PRKCA, PRKCB, CAMK2D
|
0.001598 |
| Oocyte meiosis |
6 genes: ADCY9, IGF1R, PPP2R5E, MAPK1, RPS6KA3, CAMK2D
|
0.002014 |
| Vascular smooth muscle contraction |
6 genes: ADCY9, GNAQ, GUCY1A2, PRKCA, PRKCB, MAPK1
|
0.002199 |
| mTOR signaling pathway |
4 genes: AKT3, PRKAA2, MAPK1, RPS6KA3
|
0.002948 |
| Progesterone.mediated oocyte maturation |
5 genes: AKT3, ADCY9, IGF1R, MAPK1, RPS6KA3
|
0.003251 |
| Salivary secretion |
5 genes: ADCY9, GNAQ, GUCY1A2, PRKCA, PRKCB
|
0.003586 |
| Pancreatic secretion |
5 genes: ADCY9, GNAQ, PRKCA, PRKCB, RYR2
|
0.00613 |
| Chemokine signaling pathway |
7 genes: AKT3, CHUK, ADCY9, GNB1, PRKCB, MAPK1, CCL11
|
0.006213 |
| Adherens junction |
4 genes: EGFR, IGF1R, MAPK1, TGFBR2
|
0.009841 |
| B cell receptor signaling pathway |
4 genes: AKT3, CHUK, PRKCB, MAPK1
|
0.0108 |
| VEGF signaling pathway |
4 genes: AKT3, PRKCA, PRKCB, MAPK1
|
0.0113 |
| Aldosterone.regulated sodium reabsorption |
3 genes: PRKCA, PRKCB, MAPK1
|
0.01225 |
| Phosphatidylinositol signaling system |
4 genes: DGKG, PI4K2A, PRKCA, PRKCB
|
0.01234 |
| Fc epsilon RI signaling pathway |
4 genes: AKT3, PRKCA, PRKCB, MAPK1
|
0.01289 |
| Osteoclast differentiation |
5 genes: AKT3, CHUK, MAPK1, TGFBR2, CAMK4
|
0.01601 |
| Cell adhesion molecules .CAMs. |
5 genes: NFASC, NCAM1, PECAM1, SPN, SDC3
|
0.02026 |
| Fc gamma R.mediated phagocytosis |
4 genes: AKT3, PRKCA, PRKCB, MAPK1
|
0.02373 |
| Toll.like receptor signaling pathway |
4 genes: AKT3, CHUK, MAPK1, TRAF3
|
0.0298 |
| Wnt signaling pathway |
5 genes: PRICKLE2, PPP2R5E, PRKCA, PRKCB, CAMK2D
|
0.03007 |
| Dorso.ventral axis formation |
2 genes: EGFR, MAPK1
|
0.03294 |
| Adipocytokine signaling pathway |
3 genes: AKT3, CHUK, PRKAA2
|
0.04313 |
| Mucin type O.Glycan biosynthesis |
2 genes: GALNT2, GCNT1
|
0.04603 |