| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Axon guidance |
18 genes: PLXNC1, SEMA6B, CFL2, DPYSL2, SEMA3D, NTNG1, ABL1, GNAI2, NFATC2, NFATC3, PLXNA2, PPP3R1, MAPK1, SRGAP1, RASA1, SEMA6D, UNC5C, NRP1
|
1.042e-09 |
| Neurotrophin signaling pathway |
16 genes: SH2B3, ABL1, GAB1, IRS1, NTRK2, NTRK3, PIK3CD, MAPK1, MAPK8, RPS6KA2, BDNF, YWHAG, CAMK4, CAMK2A, CAMK2D, IRS2
|
3.506e-08 |
| Long.term potentiation |
9 genes: GRM5, PPP1R12A, PPP3R1, MAPK1, RPS6KA2, CACNA1C, CAMK4, CAMK2A, CAMK2D
|
3.02e-05 |
| Ras signaling pathway |
16 genes: FGF5, BDNF, KITLG, HGF, NTRK2, IGF1R, GAB1, RASA1, PIK3CD, SHOC2, MAPK1, ETS2, KSR1, MAPK8, ABL1, ABL2
|
0.000116 |
| PI3K AKT signaling pathway |
20 genes: FGF5, BDNF, KITLG, HGF, NTRK2, IGF1R, MAPK1, IRS1, IL6R, JAK1, ITGA2, PIK3CD, PRKAA2, DDIT4, PTEN, PPP2R5E, CDK6, YWHAG, CREB1, ATF2
|
0.0001873 |
| ErbB signaling pathway |
8 genes: ABL1, GAB1, ABL2, PIK3CD, MAPK1, MAPK8, CAMK2A, CAMK2D
|
0.0008556 |
| Progesterone.mediated oocyte maturation |
8 genes: GNAI2, IGF1R, PGR, PIK3CD, MAPK1, MAPK8, RPS6KA2, CCNA1
|
0.0008556 |
| Oocyte meiosis |
9 genes: IGF1R, PGR, PPP2R5E, PPP3R1, MAPK1, RPS6KA2, YWHAG, CAMK2A, CAMK2D
|
0.001244 |
| MAPK signaling pathway |
15 genes: MAP3K2, ATF2, FGF5, NFATC2, NTRK2, PPP3R1, MAPK1, MAPK8, TAOK1, RASA1, RPS6KA2, BDNF, CACNA1C, CACNB2, CACNB4
|
0.001383 |
| Protein processing in endoplasmic reticulum |
11 genes: SEC23A, SEC24A, MAN1A2, SEC63, UBE2J1, MAPK8, EIF2AK2, RAD23B, SEC62, TXNDC5, CANX
|
0.00174 |
| Adipocytokine signaling pathway |
6 genes: CAMKK2, PPARGC1A, IRS1, PRKAA2, MAPK8, IRS2
|
0.004612 |
| Renin.angiotensin system |
3 genes: LNPEP, MME, NLN
|
0.006388 |
| mTOR signaling pathway |
5 genes: PIK3CD, DDIT4, PRKAA2, MAPK1, RPS6KA2
|
0.006615 |
| B cell receptor signaling pathway |
6 genes: LYN, NFATC2, NFATC3, PIK3CD, PPP3R1, MAPK1
|
0.007427 |
| Calcium signaling pathway |
10 genes: ADRA1D, EDNRA, GRM5, ATP2A2, PPP3R1, PTGER3, CACNA1C, CAMK4, CAMK2A, CAMK2D
|
0.007785 |
| Wnt signaling pathway |
9 genes: CSNK1A1, SMAD4, NFATC2, NFATC3, PPP2R5E, PPP3R1, MAPK8, CAMK2A, CAMK2D
|
0.008109 |
| Osteoclast differentiation |
8 genes: CREB1, CYLD, JAK1, NFATC2, PIK3CD, MAPK1, MAPK8, CAMK4
|
0.009339 |
| Insulin signaling pathway |
8 genes: PPARGC1A, IRS1, PIK3CD, PRKAA2, PRKAR1A, MAPK1, MAPK8, IRS2
|
0.01426 |
| Circadian rhythm . mammal |
3 genes: RORA, PER2, CLOCK
|
0.01503 |
| Aldosterone.regulated sodium reabsorption |
4 genes: IRS1, PIK3CD, MAPK1, IRS2
|
0.01529 |
| Dorso.ventral axis formation |
3 genes: ETS2, MAPK1, SPIRE1
|
0.01888 |
| Nucleotide excision repair |
4 genes: ERCC4, GTF2H1, RAD23B, CUL4B
|
0.0193 |
| Long.term depression |
5 genes: GNAI2, GRM5, IGF1R, LYN, MAPK1
|
0.0221 |
| GnRH signaling pathway |
6 genes: MAP3K2, MAPK1, MAPK8, CACNA1C, CAMK2A, CAMK2D
|
0.02863 |
| Melanogenesis |
6 genes: CREB1, GNAI2, KITLG, MAPK1, CAMK2A, CAMK2D
|
0.02863 |
| VEGF signaling pathway |
5 genes: NFATC2, NFATC3, PIK3CD, PPP3R1, MAPK1
|
0.03023 |
| Mucin type O.Glycan biosynthesis |
3 genes: GALNT13, GALNT2, B4GALT5
|
0.03065 |
| Cardiac muscle contraction |
5 genes: ATP2A2, ACTC1, CACNA1C, CACNB2, CACNB4
|
0.03174 |
| Focal adhesion |
9 genes: HGF, IGF1R, ITGA2, PPP1R12A, PIK3CD, MAPK1, MAPK8, PTEN, TLN2
|
0.04131 |
| Inositol phosphate metabolism |
4 genes: IPMK, PIK3CD, PIP4K2A, PTEN
|
0.04141 |
| TGF.beta signaling pathway |
5 genes: INHBA, SMAD4, MAPK1, BMPR2, ACVR1
|
0.04556 |