Enriched cancer pathwayGenes under regulationP value
Hippo signaling pathway
19 genes: WTIP, STK3, DLG2, FBXW11, TEAD1, CTGF, TGFB2, TGFBR1, SMAD7, SMAD4, GDF6, BMPR1B, WNT9A, WNT11, FZD7, YWHAH, CTNNB1, CCND3, SNAI2
1.192e-07
Melanogenesis
13 genes: ADCY5, ADCY7, ADCY9, CTNNB1, EDN1, GNAO1, KITLG, PRKACB, TYRP1, WNT11, WNT9A, CALM1, FZD7
7.352e-06
Gap junction
12 genes: TUBA1B, ADCY5, ADCY7, ADCY9, GNA11, GUCY1A2, PRKACB, PRKG1, PDGFC, MAP2K5, TUBA4A, TUBA1A
1.141e-05
Focal adhesion
16 genes: COL1A1, COL5A2, COL6A3, CTNNB1, TNC, IGF1R, ILK, ITGA1, ITGA9, SHC4, PDGFC, PTEN, RAP1A, ROCK1, CAV2, CCND3
0.0002615
TGF.beta signaling pathway
9 genes: CDKN2B, GDF6, SMAD4, SMAD7, ROCK1, BMPR1B, TGFB2, TGFBR1, ACVR1
0.0008111
ECM.receptor interaction
9 genes: COL1A1, COL5A2, COL6A3, TNC, ITGA1, ITGA9, CD44, CD47, SDC3
0.0008111
Glycosaminoglycan biosynthesis . heparan sulfate
5 genes: EXT1, EXT2, GLCE, XYLT1, HS3ST3B1
0.0008125
Neurotrophin signaling pathway
11 genes: IRAK3, FOXO3, SHC4, MAP3K3, NTRK3, MAP2K5, RAP1A, BDNF, YWHAH, CALM1, CAMK4
0.001221
PI3K AKT signaling pathway
21 genes: FGF2, BDNF, PDGFC, KITLG, FGFR1, IGF1R, IL6R, IL7R, COL1A1, COL4A3, COL6A3, TNC, ITGA1, ITGA9, PRKAA2, PTEN, CDK6, CCND3, FOXO3, YWHAH, CREB5
0.001552
Wnt signaling pathway
12 genes: PRICKLE1, CTNNB1, PRICKLE2, FBXW11, SMAD4, PRKACB, ROCK1, TBL1X, WNT11, WNT9A, FZD7, CCND3
0.001574
Calcium signaling pathway
13 genes: ADCY7, ADCY9, GNA11, HRH1, ATP2B4, PDE1C, PDE1B, PRKACB, PTGER3, PTGFR, CALM1, CAMK4, SPHK1
0.002081
Cell adhesion molecules .CAMs.
11 genes: NFASC, CNTNAP2, ITGA9, CD99, CADM3, PVR, JAM2, CD276, CD8B, NRXN1, SDC3
0.002116
GnRH signaling pathway
9 genes: ADCY5, ADCY7, ADCY9, HBEGF, GNA11, MAP3K3, MMP2, PRKACB, CALM1
0.002734
Long.term depression
7 genes: GNA11, GNAO1, GRIA3, GUCY1A2, IGF1R, LYN, PRKG1
0.004191
Salivary secretion
8 genes: ADCY5, ADCY7, ADCY9, GUCY1A2, ATP2B4, PRKACB, PRKG1, CALM1
0.004388
Adherens junction
7 genes: CTNNB1, FER, FGFR1, IGF1R, SMAD4, SNAI2, TGFBR1
0.005288
Vascular smooth muscle contraction
9 genes: ADCY5, ADCY7, ADCY9, GNA11, GUCY1A2, PRKACB, PRKG1, ROCK1, CALM1
0.006821
Chemokine signaling pathway
12 genes: ADCY5, ADCY7, ADCY9, CCR6, FOXO3, SHC4, LYN, PRKACB, RAP1A, ROCK1, CXCL5, ELMO1
0.009521
MAPK signaling pathway
15 genes: DUSP7, FGF2, FGFR1, MEF2C, MAP3K3, PRKACB, MAP2K5, RAP1A, RASGRF2, BDNF, STK3, TGFB2, TGFBR1, CACNA2D1, CACNB4
0.01225
Hematopoietic cell lineage
7 genes: IL6R, IL7R, ITGA1, KITLG, MME, CD8B, CD44
0.01423
Bile secretion
6 genes: ADCY5, ADCY7, ADCY9, AQP4, AQP9, PRKACB
0.01718
Oocyte meiosis
8 genes: ADCY5, ADCY7, ADCY9, FBXW11, IGF1R, PRKACB, YWHAH, CALM1
0.01831
Ras signaling pathway
13 genes: FGF2, BDNF, PDGFC, KITLG, FGFR1, IGF1R, SHC4, PRKACB, RASGRF2, CALM1, RAPGEF5, RAP1A, RALB
0.0212
Hedgehog signaling pathway
5 genes: FBXW11, GLI3, PRKACB, WNT11, WNT9A
0.02317
Vasopressin.regulated water reabsorption
4 genes: ADCY9, AQP4, PRKACB, CREB5
0.03852
Purine metabolism
9 genes: ADCY5, ADCY7, ADCY9, GUCY1A2, PDE1C, PDE1B, POLE3, RRM1, PDE5A
0.0477