Enriched cancer pathwayGenes under regulationP value
ECM.receptor interaction
11 genes: COL1A2, COL4A4, FN1, ITGA2, ITGA9, ITGAV, LAMC1, SDC2, THBS1, CD44, CD47
1.332e-05
Focal adhesion
17 genes: AKT3, COL1A2, COL4A4, FN1, HGF, IGF1, IGF1R, ITGA2, ITGA9, ITGAV, LAMC1, MYLK, PARVA, THBS1, CAPN2, CAV2, CCND2
2.201e-05
PI3K AKT signaling pathway
22 genes: FGF7, FGF5, BDNF, IGF1, KITLG, HGF, IGF1R, GHR, COL1A2, COL4A4, COL4A3, LAMC1, THBS1, FN1, ITGA2, ITGA9, ITGAV, GNB4, PRKAA2, AKT3, CCND2, CREB5
0.000158
Hippo signaling pathway
13 genes: YAP1, FRMD6, STK3, LATS2, DLG2, GLI2, TGFB2, TGFBR2, BMPR2, FZD7, LEF1, CCND2, SNAI2
0.0002141
Ras signaling pathway
16 genes: FGF7, FGF5, BDNF, IGF1, KITLG, HGF, IGF1R, GNB4, GRIN2A, CALM1, MRAS, RRAS2, AKT3, PLA2G4A, RAPGEF5, ABL2
0.0005203
Regulation of actin cytoskeleton
15 genes: CFL2, FGF5, FGF7, RRAS2, MRAS, FN1, GNA12, ITGA2, ITGA9, ITGAV, MYLK, PIP4K2A, SSH1, ENAH, IQGAP1
0.0005452
Pantothenate and CoA biosynthesis
4 genes: DPYD, ENPP1, BCAT1, VNN1
0.0006598
Cell adhesion molecules .CAMs.
11 genes: VCAN, NLGN1, NEGR1, ICOS, ITGA9, ITGAV, NCAM2, PVR, JAM2, SDC2, NRXN1
0.0009199
Jak.STAT signaling pathway
11 genes: AKT3, IL22RA2, SPRED1, GHR, IL6ST, LEP, LEPR, LIF, TPO, TSLP, CCND2
0.002625
Circadian rhythm . mammal
4 genes: RORA, RORB, PER3, PER2
0.002776
MAPK signaling pathway
15 genes: AKT3, FGF5, FGF7, RRAS2, MRAS, GNA12, MEF2C, PLA2G4A, PPP3CA, BDNF, STK3, TGFB2, TGFBR2, CACNA2D1, CACNB4
0.004919
Osteoclast differentiation
9 genes: AKT3, LILRB4, CYLD, FCGR2B, MITF, PPP3CA, TGFB2, TGFBR2, CAMK4
0.006611
Axon guidance
9 genes: CFL2, SEMA3D, NTNG1, PPP3CA, ROBO1, SLIT3, SEMA6D, UNC5C, SEMA3E
0.007296
Long.term depression
6 genes: GNA12, IGF1, IGF1R, ITPR1, PLA2G4A, PRKG1
0.01001
Adherens junction
6 genes: FER, IGF1R, LEF1, SNAI2, TGFBR2, IQGAP1
0.01218
Adipocytokine signaling pathway
5 genes: AKT3, PPARGC1A, LEP, LEPR, PRKAA2
0.03276
Long.term potentiation
5 genes: GRIN2A, ITPR1, PPP3CA, CALM1, CAMK4
0.03648
Calcium signaling pathway
9 genes: GRIN2A, ITPR1, MYLK, PPP3CA, PTGER3, PTGFR, SLC8A1, CALM1, CAMK4
0.04394
Wnt signaling pathway
8 genes: PRICKLE2, DKK2, LEF1, PPP3CA, SFRP1, SFRP2, FZD7, CCND2
0.0456
mTOR signaling pathway
4 genes: AKT3, IGF1, CAB39, PRKAA2
0.047
Melanogenesis
6 genes: EDN1, KITLG, MITF, LEF1, CALM1, FZD7
0.04967