| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Vascular smooth muscle contraction |
9 genes: MRVI1, ARHGEF12, KCNMA1, MYLK, PPP1R12A, PPP1R12B, PRKACB, PRKCA, MAPK1
|
3.924e-06 |
| MAPK signaling pathway |
12 genes: AKT3, GADD45A, DUSP7, EGFR, ELK4, NF1, NTRK2, PRKACB, PRKCA, MAPK1, TGFB2, MAP3K6
|
2.927e-05 |
| Gastric acid secretion |
5 genes: CHRM3, KCNJ2, MYLK, PRKACB, PRKCA
|
0.001113 |
| Regulation of actin cytoskeleton |
8 genes: ABI2, NCKAP1, CHRM3, EGFR, ARHGEF12, MYLK, PPP1R12A, MAPK1
|
0.002015 |
| TGF.beta signaling pathway |
5 genes: SMAD2, SMAD5, MAPK1, TGFB2, ACVR2A
|
0.002064 |
| Salivary secretion |
5 genes: CHRM3, KCNMA1, ATP2B4, PRKACB, PRKCA
|
0.002525 |
| Axon guidance |
6 genes: SEMA3A, NFAT5, UNC5B, ARHGEF12, MAPK1, SLIT3
|
0.002591 |
| Gap junction |
5 genes: EGFR, PRKACB, PRKCA, MAPK1, TUBA1A
|
0.002651 |
| Wnt signaling pathway |
6 genes: NFAT5, PRICKLE2, LRP6, SMAD2, PRKACB, PRKCA
|
0.005396 |
| Long.term potentiation |
4 genes: PPP1R12A, PRKACB, PRKCA, MAPK1
|
0.006415 |
| VEGF signaling pathway |
4 genes: AKT3, NFAT5, PRKCA, MAPK1
|
0.008549 |
| Vasopressin.regulated water reabsorption |
3 genes: CREB1, PRKACB, CREB5
|
0.01116 |
| Calcium signaling pathway |
6 genes: CHRM3, EGFR, MYLK, ATP2B4, PRKACB, PRKCA
|
0.01136 |
| Osteoclast differentiation |
5 genes: AKT3, CREB1, CYLD, MAPK1, TGFB2
|
0.01159 |
| Ras signaling pathway |
7 genes: EGFR, NTRK2, PRKACB, NF1, AKT3, MAPK1, PRKCA
|
0.01285 |
| ErbB signaling pathway |
4 genes: AKT3, EGFR, PRKCA, MAPK1
|
0.01357 |
| Progesterone.mediated oocyte maturation |
4 genes: AKT3, PDE3A, PRKACB, MAPK1
|
0.01357 |
| Focal adhesion |
6 genes: AKT3, EGFR, MYLK, PPP1R12A, PRKCA, MAPK1
|
0.01963 |
| GnRH signaling pathway |
4 genes: EGFR, PRKACB, PRKCA, MAPK1
|
0.02223 |
| Melanogenesis |
4 genes: CREB1, PRKACB, PRKCA, MAPK1
|
0.02223 |
| Pancreatic secretion |
4 genes: CHRM3, KCNMA1, ATP2B4, PRKCA
|
0.02223 |
| Glycosaminoglycan biosynthesis . chondroitin sulfate |
2 genes: CHSY1, XYLT1
|
0.02228 |
| Dorso.ventral axis formation |
2 genes: EGFR, MAPK1
|
0.02834 |
| Glycosaminoglycan biosynthesis . heparan sulfate |
2 genes: NDST1, XYLT1
|
0.03049 |
| PI3K AKT signaling pathway |
8 genes: EGFR, NTRK2, MAPK1, PRKCA, AKT3, CDK6, CREB1, CREB5
|
0.03323 |
| p53 signaling pathway |
3 genes: CDK6, GADD45A, ZMAT3
|
0.03649 |
| Long.term depression |
3 genes: GRIA3, PRKCA, MAPK1
|
0.03783 |
| Adherens junction |
3 genes: EGFR, SMAD2, MAPK1
|
0.04202 |
| B cell receptor signaling pathway |
3 genes: AKT3, NFAT5, MAPK1
|
0.04494 |
| Cell cycle |
4 genes: CDK6, GADD45A, SMAD2, TGFB2
|
0.0468 |