Enriched cancer pathwayGenes under regulationP value
Long.term potentiation
6 genes: EP300, PLCB1, GNAQ, PPP1R12A, PPP1CB, PRKCA
0.0003863
Focal adhesion
10 genes: CRK, IGF1R, ARHGAP5, PPP1R12A, PIK3R1, PPP1CB, PRKCA, SOS1, TLN1, ROCK2
0.0004412
TGF.beta signaling pathway
6 genes: EP300, SMAD4, SMAD5, ACVR2A, ROCK2, ZFYVE16
0.001087
Vascular smooth muscle contraction
6 genes: PLCB1, GNAQ, PPP1R12A, PPP1CB, PRKCA, ROCK2
0.005201
ErbB signaling pathway
5 genes: CRK, GAB1, PIK3R1, PRKCA, SOS1
0.006798
Gap junction
5 genes: PLCB1, GNAQ, PRKCA, SOS1, TJP1
0.007825
Regulation of actin cytoskeleton
8 genes: ABI2, CRK, DIAPH2, PPP1R12A, PIK3R1, PPP1CB, SOS1, ROCK2
0.009346
MAPK signaling pathway
9 genes: CRK, IKBKB, PPM1A, PPM1B, PRKCA, SOS1, CACNB2, MAP3K13, RAPGEF2
0.01165
Long.term depression
4 genes: PLCB1, GNAQ, IGF1R, PRKCA
0.01541
Wnt signaling pathway
6 genes: EP300, PLCB1, FBXW11, SMAD4, PRKCA, ROCK2
0.01766
Adherens junction
4 genes: EP300, IGF1R, SMAD4, TJP1
0.01772
Neurotrophin signaling pathway
5 genes: CRK, GAB1, IKBKB, PIK3R1, SOS1
0.03029
Protein export
2 genes: SEC62, IMMP2L
0.0389
Circadian rhythm . mammal
2 genes: FBXW11, PER3
0.0389
Insulin signaling pathway
5 genes: CRK, IKBKB, PIK3R1, PPP1CB, SOS1
0.04103
Ras signaling pathway
7 genes: IGF1R, GAB1, SOS1, PIK3R1, IKBKB, PRKCA, RAB5B
0.04374
Chemokine signaling pathway
6 genes: CRK, PLCB1, IKBKB, PIK3R1, SOS1, ROCK2
0.04555
GnRH signaling pathway
4 genes: PLCB1, GNAQ, PRKCA, SOS1
0.04967
Melanogenesis
4 genes: EP300, PLCB1, GNAQ, PRKCA
0.04967