| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Neurotrophin signaling pathway |
9 genes: SH2B3, YWHAQ, NTRK3, PIK3CD, MAPK1, RAP1A, BDNF, CAMK4, CAMK2A
|
9.602e-06 |
| Ras signaling pathway |
12 genes: FGF1, FGF5, BDNF, IGF1, EGFR, IGF1R, GNG4, GNG7, RASA4, PIK3CD, MAPK1, RAP1A
|
9.978e-06 |
| Glycosaminoglycan biosynthesis . chondroitin sulfate |
4 genes: CHST11, CSGALNACT2, XYLT1, CHST3
|
8.16e-05 |
| Long.term depression |
6 genes: GNA11, GNA12, GNAO1, IGF1, IGF1R, MAPK1
|
0.0001064 |
| ErbB signaling pathway |
6 genes: EGFR, EREG, PIK3CD, MAPK1, CAMK2A, CBL
|
0.0003522 |
| MAPK signaling pathway |
10 genes: MAP3K2, DUSP3, EGFR, FGF1, FGF5, GNA12, MAPK1, MAP2K3, RAP1A, BDNF
|
0.0006715 |
| GnRH signaling pathway |
6 genes: MAP3K2, EGFR, GNA11, MAPK1, MAP2K3, CAMK2A
|
0.0007808 |
| Adherens junction |
5 genes: SORBS1, CTNNB1, EGFR, IGF1R, MAPK1
|
0.001137 |
| PI3K AKT signaling pathway |
11 genes: FGF1, FGF5, BDNF, IGF1, EGFR, IGF1R, MAPK1, PIK3CD, GNG4, GNG7, YWHAQ
|
0.00152 |
| Melanogenesis |
5 genes: CTNNB1, GNAO1, MAPK1, WNT7A, CAMK2A
|
0.004711 |
| Focal adhesion |
7 genes: CTNNB1, EGFR, IGF1, IGF1R, PIK3CD, MAPK1, RAP1A
|
0.006004 |
| Long.term potentiation |
4 genes: MAPK1, RAP1A, CAMK4, CAMK2A
|
0.006847 |
| Oocyte meiosis |
5 genes: YWHAQ, IGF1, IGF1R, MAPK1, CAMK2A
|
0.00781 |
| Regulation of actin cytoskeleton |
7 genes: EGFR, FGF1, FGF5, GNA12, PIK3CD, PIP4K2A, MAPK1
|
0.008571 |
| Aldosterone.regulated sodium reabsorption |
3 genes: IGF1, PIK3CD, MAPK1
|
0.01033 |
| Calcium signaling pathway |
6 genes: EGFR, GNA11, ATP2B4, SLC8A1, CAMK4, CAMK2A
|
0.01238 |
| Osteoclast differentiation |
5 genes: SIRPA, FCGR3A, PIK3CD, MAPK1, CAMK4
|
0.01249 |
| Progesterone.mediated oocyte maturation |
4 genes: IGF1, IGF1R, PIK3CD, MAPK1
|
0.01444 |
| Gap junction |
4 genes: MAP3K2, EGFR, GNA11, MAPK1
|
0.01618 |
| Insulin signaling pathway |
5 genes: SORBS1, PIK3CD, PRKAR2A, MAPK1, CBL
|
0.0168 |
| mTOR signaling pathway |
3 genes: IGF1, PIK3CD, MAPK1
|
0.0184 |
| Toll.like receptor signaling pathway |
4 genes: PIK3CD, MAPK1, MAP2K3, TRAF3
|
0.02438 |
| Hippo signaling pathway |
5 genes: WWTR1, FGF1, WNT7A, YWHAQ, CTNNB1
|
0.02558 |
| Dorso.ventral axis formation |
2 genes: EGFR, MAPK1
|
0.02934 |
| Glycosaminoglycan biosynthesis . heparan sulfate |
2 genes: EXT1, XYLT1
|
0.03156 |
| Vascular smooth muscle contraction |
4 genes: GNA11, GNA12, MAPK1, PTGIR
|
0.03664 |