| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Calcium signaling pathway |
17 genes: ADRB2, PTK2B, GNA11, GNAL, ATP2B4, PDE1A, PDE1C, PDGFRA, PHKB, PLCB4, PPP3CB, PRKACB, PRKCA, PRKCB, RYR2, CACNA1C, CALM1
|
5.469e-06 |
| MAPK signaling pathway |
20 genes: DUSP7, DUSP8, FGF2, FGF9, HSPA2, MEF2C, MAP3K3, NFKB1, PDGFRA, PPM1A, PPP3CB, PRKACB, PRKCA, PRKCB, MAPK10, TGFB3, TRAF6, CACNA1C, CACNA2D1, CACNB4
|
3.658e-05 |
| Wnt signaling pathway |
14 genes: CSNK1A1, PRICKLE2, FBXW11, APC, SMAD2, SMAD4, PLCB4, PPP3CB, PRKACB, PRKCA, PRKCB, MAPK10, SKP1, CCND2
|
5.378e-05 |
| GnRH signaling pathway |
11 genes: ADCY5, PTK2B, GNA11, MAP3K3, PLCB4, PRKACB, PRKCA, PRKCB, MAPK10, CACNA1C, CALM1
|
7.927e-05 |
| Long.term potentiation |
9 genes: PPP1R12A, PLCB4, PPP1CB, PPP3CB, PRKACB, PRKCA, PRKCB, CACNA1C, CALM1
|
9.715e-05 |
| Vascular smooth muscle contraction |
11 genes: ADCY5, GNA11, KCNMA1, PPP1R12A, PLCB4, PPP1CB, PRKACB, PRKCA, PRKCB, CACNA1C, CALM1
|
0.0002741 |
| TGF.beta signaling pathway |
9 genes: SMAD2, SMAD4, SKP1, BMP5, BMP7, BMPR2, TGFB3, THBS1, ACVR1
|
0.0004324 |
| Salivary secretion |
9 genes: ADCY5, ADRB2, KCNMA1, ATP2B4, PLCB4, PRKACB, PRKCA, PRKCB, CALM1
|
0.0006078 |
| Ras signaling pathway |
16 genes: FGF2, FGF9, KITLG, PDGFRA, KIT, PRKACB, CALM1, RASA3, RASSF5, PIK3R1, NFKB1, ETS2, RAPGEF5, MAPK10, PRKCA, PRKCB
|
0.0006247 |
| Hippo signaling pathway |
12 genes: PPP2R2A, PPP1CB, FBXW11, TEAD1, TGFB3, SMAD2, SMAD4, BMP5, BMP7, BMPR2, APC, CCND2
|
0.0008834 |
| Endocytosis |
14 genes: STAM2, WWP1, VPS37A, ADRB2, DNM3, HSPA2, KIT, SMAD2, VPS36, PDGFRA, PML, TGFB3, TRAF6, VPS4B
|
0.001136 |
| Melanogenesis |
9 genes: ADCY5, EDN1, KIT, KITLG, PLCB4, PRKACB, PRKCA, PRKCB, CALM1
|
0.001509 |
| Neurotrophin signaling pathway |
10 genes: IRAK3, FOXO3, MAP3K3, NFKB1, PIK3R1, MAPK10, BCL2, TRAF6, CALM1, IRS2
|
0.002147 |
| Apoptosis |
8 genes: IRAK3, ENDOD1, NFKB1, PIK3R1, PPP3CB, PRKACB, PRKAR2B, BCL2
|
0.002577 |
| Gap junction |
8 genes: ADCY5, GNA11, PDGFRA, PLCB4, PRKACB, PRKCA, PRKCB, TUBA4A
|
0.002764 |
| Focal adhesion |
13 genes: DIAPH1, ARHGAP5, PPP1R12A, PDGFRA, PIK3R1, PPP1CB, PRKCA, PRKCB, MAPK10, BCL2, THBS1, ACTN1, CCND2
|
0.002833 |
| Oocyte meiosis |
9 genes: ADCY5, FBXW11, AR, PPP1CB, PPP3CB, PRKACB, CPEB1, SKP1, CALM1
|
0.00346 |
| Gastric acid secretion |
7 genes: ADCY5, PLCB4, KCNK10, PRKACB, PRKCA, PRKCB, CALM1
|
0.00354 |
| Hedgehog signaling pathway |
6 genes: CSNK1A1, FBXW11, RAB23, PRKACB, BMP5, BMP7
|
0.003659 |
| Phosphatidylinositol signaling system |
7 genes: DGKB, DGKG, PIK3R1, PLCB4, PRKCA, PRKCB, CALM1
|
0.004746 |
| Aldosterone.regulated sodium reabsorption |
5 genes: NR3C2, PIK3R1, PRKCA, PRKCB, IRS2
|
0.004976 |
| Insulin signaling pathway |
9 genes: FOXO1, PHKB, PIK3R1, PPP1CB, PRKACB, PRKAR2B, MAPK10, CALM1, IRS2
|
0.01174 |
| Ubiquitin mediated proteolysis |
9 genes: WWP1, FBXW11, PML, SKP1, TRAF6, UBE2D3, CUL5, CUL3, HERC3
|
0.01227 |
| Chemokine signaling pathway |
11 genes: ADCY5, CCR4, CCR6, PTK2B, FOXO3, NFKB1, PIK3R1, PLCB4, PRKACB, PRKCB, STAT5B
|
0.01273 |
| Leukocyte transendothelial migration |
8 genes: PTK2B, ARHGAP5, PIK3R1, PRKCA, PRKCB, JAM2, RASSF5, ACTN1
|
0.0131 |
| Pancreatic secretion |
7 genes: ADCY5, KCNMA1, ATP2B4, PLCB4, PRKCA, PRKCB, RYR2
|
0.01841 |
| Circadian rhythm . mammal |
3 genes: FBXW11, SKP1, PER2
|
0.02243 |
| Regulation of actin cytoskeleton |
11 genes: ARPC2, CFL2, DIAPH1, FGF2, FGF9, APC, PPP1R12A, PDGFRA, PIK3R1, PPP1CB, ACTN1
|
0.02888 |
| Fc gamma R.mediated phagocytosis |
6 genes: ARPC2, CFL2, DNM3, PIK3R1, PRKCA, PRKCB
|
0.04149 |