| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Focal adhesion |
17 genes: FLNA, IGF1R, ITGA5, ITGA9, ITGB5, LAMB2, ARHGAP5, PDGFA, PDGFRB, PDPK1, PIK3CD, PPP1CB, PRKCB, PTEN, ACTB, TLN1, ITGA10
|
2.451e-06 |
| MAPK signaling pathway |
18 genes: RASGRP2, DUSP3, FGF1, FGF7, FLNA, MAPT, MAX, MAP3K3, NFATC2, NFATC4, PDGFA, PDGFRB, PPM1A, PRKCB, PTPN7, SRF, CACNA1C, MAPKAPK2
|
3.239e-05 |
| Regulation of actin cytoskeleton |
13 genes: FGF1, FGF7, ITGA5, ITGA9, ITGB5, MYH9, PDGFA, PDGFRB, PIK3CD, PPP1CB, ACTB, BDKRB2, ITGA10
|
0.001015 |
| Wnt signaling pathway |
10 genes: PRICKLE2, SMAD2, NFATC2, NFATC4, PPP2R5A, PRKCB, SFRP1, TBL1X, CAMK2D, FZD4
|
0.002009 |
| Calcium signaling pathway |
11 genes: GNA11, ATP2A2, PDGFRB, PHKB, PRKCB, BDKRB2, TACR1, CACNA1C, CALM1, CAMK2D, SPHK1
|
0.002027 |
| Aldosterone.regulated sodium reabsorption |
5 genes: ATP1B2, PDPK1, PIK3CD, PRKCB, IRS2
|
0.002258 |
| PI3K AKT signaling pathway |
17 genes: FGF1, FGF7, PDGFA, IGF1R, PDGFRB, IL6R, IFNAR1, LAMB2, ITGA5, ITGA9, ITGA10, ITGB5, PIK3CD, PDPK1, EIF4B, PTEN, PPP2R5A
|
0.002264 |
| Insulin signaling pathway |
9 genes: FLOT1, GCK, PDPK1, PHKB, PIK3CD, PPP1CB, PYGB, CALM1, IRS2
|
0.003672 |
| Vascular smooth muscle contraction |
8 genes: RAMP3, GNA11, PPP1CB, PRKCB, ACTA2, CACNA1C, CALD1, CALM1
|
0.00431 |
| Long.term potentiation |
6 genes: RAPGEF3, PPP1CB, PRKCB, CACNA1C, CALM1, CAMK2D
|
0.004532 |
| VEGF signaling pathway |
6 genes: NFATC2, NFATC4, PIK3CD, PRKCB, SPHK1, MAPKAPK2
|
0.006766 |
| GnRH signaling pathway |
7 genes: GNA11, MAP3K3, MMP14, PRKCB, CACNA1C, CALM1, CAMK2D
|
0.007203 |
| Hippo signaling pathway |
9 genes: YAP1, WTIP, SAV1, PPP1CB, DLG2, FGF1, SMAD2, FZD4, ACTB
|
0.00746 |
| Phosphatidylinositol signaling system |
6 genes: IMPA2, OCRL, PIK3CD, PRKCB, PTEN, CALM1
|
0.007663 |
| ECM.receptor interaction |
6 genes: HSPG2, ITGA5, ITGA9, ITGB5, LAMB2, ITGA10
|
0.01148 |
| Glycosaminoglycan biosynthesis . chondroitin sulfate |
3 genes: CHSY3, CHST11, CHST3
|
0.01216 |
| Long.term depression |
5 genes: GNA11, GNAO1, GRIA3, IGF1R, PRKCB
|
0.01946 |
| Neurotrophin signaling pathway |
7 genes: ABL1, MAP3K3, PIK3CD, CALM1, CAMK2D, IRS2, MAPKAPK2
|
0.02308 |
| Gastric acid secretion |
5 genes: ATP1B2, PRKCB, ACTB, CALM1, CAMK2D
|
0.02412 |
| Tight junction |
7 genes: AMOTL1, EPB41L2, HCLS1, MYH9, PRKCB, PTEN, ACTB
|
0.02877 |
| Cell adhesion molecules .CAMs. |
7 genes: NFASC, HLA-DOB, ITGA9, L1CAM, NEO1, CNTN2, CD40LG
|
0.03194 |
| Inositol phosphate metabolism |
4 genes: IMPA2, OCRL, PIK3CD, PTEN
|
0.03737 |
| Ras signaling pathway |
10 genes: FGF1, FGF7, PDGFA, IGF1R, PDGFRB, RASGRP2, CALM1, PIK3CD, PRKCB, ABL1
|
0.03809 |