Enriched cancer pathwayGenes under regulationP value
p53 signaling pathway
6 genes: CDK6, SESN3, GADD45A, ATM, THBS1, CCND2
0.0002587
Propanoate metabolism
4 genes: ABAT, ACACB, ALDH6A1, ALDH7A1
0.0007216
TGF.beta signaling pathway
6 genes: SMAD4, SMAD5, TGFB2, TGFBR1, THBS1, ROCK2
0.0007957
Axon guidance
7 genes: NFAT5, PLXNA2, ROBO2, SLIT3, UNC5C, ROCK2, SEMA3E
0.001474
Wnt signaling pathway
7 genes: NFAT5, PRICKLE2, LRP6, SMAD4, PRKCA, CCND2, ROCK2
0.003432
Cell cycle
6 genes: CDK6, GADD45A, SMAD4, ATM, TGFB2, CCND2
0.006258
Adipocytokine signaling pathway
4 genes: ACACB, PPARA, PRKAA2, PRKAB2
0.01141
RNA degradation
4 genes: TOB2, CNOT1, CNOT6L, DCP1A
0.01321
Valine. leucine and isoleucine degradation
3 genes: ABAT, ALDH6A1, ALDH7A1
0.01885
Calcium signaling pathway
6 genes: CHRM3, ATP2A2, PDE1C, PRKCA, RYR2, CAMK4
0.02709
beta.Alanine metabolism
2 genes: ABAT, ALDH7A1
0.03209
Lysine biosynthesis
1 genes: ALDH7A1
0.03806
Pancreatic secretion
4 genes: CHRM3, ATP2A2, PRKCA, RYR2
0.04136
Glycosaminoglycan biosynthesis . heparan sulfate
2 genes: B3GAT2, EXTL3
0.04366
Focal adhesion
6 genes: XIAP, ARHGAP5, PRKCA, THBS1, CCND2, ROCK2
0.04488
Hippo signaling pathway
5 genes: PPP2R2A, TGFB2, TGFBR1, SMAD4, CCND2
0.04893