Enriched cancer pathwayGenes under regulationP value
Long.term potentiation
7 genes: GNAQ, GRIN2A, PPP1R12A, PPP1CB, CACNA1C, CAMK4, CAMK2D
0.0003087
Focal adhesion
11 genes: COL5A1, HGF, ITGB8, MYLK, PPP1R12A, PPP1CB, RELN, BCL2, ROCK1, CAV2, ROCK2
0.001296
Vascular smooth muscle contraction
8 genes: GNAQ, KCNMA1, MYLK, PPP1R12A, PPP1CB, ROCK1, CACNA1C, ROCK2
0.001426
Calcium signaling pathway
10 genes: CHRM3, F2R, GNAQ, GRIN2A, SLC25A4, MYLK, RYR2, CACNA1C, CAMK4, CAMK2D
0.001743
Regulation of actin cytoskeleton
11 genes: CHRM3, F2R, FGF5, MRAS, ITGB8, MYH10, MYLK, PPP1R12A, PPP1CB, ROCK1, ROCK2
0.002214
Neurotrophin signaling pathway
8 genes: MAPK14, MAP3K1, PTPN11, BCL2, SORT1, CAMK4, CAMK2D, IRS2
0.002528
Axon guidance
7 genes: EFNB2, DPYSL5, RASA1, ROCK1, SEMA6D, NRP1, ROCK2
0.01065
GnRH signaling pathway
6 genes: MAP3K2, MAPK14, GNAQ, MAP3K1, CACNA1C, CAMK2D
0.01121
MAPK signaling pathway
11 genes: RASGRP1, MAP3K2, ATF2, MAPK14, FGF5, MRAS, MAP3K1, TAOK1, RASA1, STK3, CACNA1C
0.01159
PI3K AKT signaling pathway
13 genes: FGF5, HGF, PIK3AP1, PRLR, RELN, ITGB8, F2R, GNB4, PRKAA2, SGK3, BCL2, ATF2, MCL1
0.01419
Insulin signaling pathway
7 genes: SORBS1, PPARGC1A, PPP1CB, PRKAA2, PRKAR2A, SOCS1, IRS2
0.01443
TGF.beta signaling pathway
5 genes: CDKN2B, ROCK1, BMPR1B, BMPR2, ROCK2
0.02074
Regulation of autophagy
3 genes: PRKAA2, ATG4C, ULK2
0.02461
Adipocytokine signaling pathway
4 genes: PPARGC1A, PRKAA2, PTPN11, IRS2
0.03721
Tight junction
6 genes: AMOTL1, MRAS, EPB41L3, MAGI3, MYH10, JAM3
0.03739
Renin.angiotensin system
2 genes: CTSA, NLN
0.03865
Melanogenesis
5 genes: GNAO1, GNAQ, MITF, TYRP1, CAMK2D
0.03959
Cell adhesion molecules .CAMs.
6 genes: CDH2, NFASC, NEGR1, ITGB8, CNTN2, JAM3
0.04096
Gastric acid secretion
4 genes: CHRM3, GNAQ, MYLK, CAMK2D
0.04831