| Enriched cancer pathway | Genes under regulation | P value |
|---|
| Focal adhesion |
14 genes: PIP5K1C, IGF1, IGF1R, ILK, JUN, RHOA, PPP1R12A, COL5A3, PDGFB, THBS1, VCL, TLN2, ITGA10, CCND3
|
4.157e-05 |
| Axon guidance |
10 genes: CFL2, GNAI2, RHOA, NFATC1, NFATC4, PLXNA2, RGS3, SLIT3, ABLIM2, UNC5A
|
0.0002416 |
| Long.term depression |
7 genes: GNA11, GNA12, GNAI2, IGF1, IGF1R, ITPR2, PPP2CB
|
0.0004301 |
| PI3K AKT signaling pathway |
17 genes: IGF1, PDGFB, CSF1, NTRK2, IGF1R, PIK3AP1, CSF3R, THBS1, ITGA10, GNG4, GNG7, PPP2CB, TCL1A, CCND3, FOXO3, CREB5, MCL1
|
0.0005894 |
| Ras signaling pathway |
12 genes: IGF1, PDGFB, CSF1, NTRK2, IGF1R, RASGRP2, GNG4, GNG7, RASA4, RHOA, ETS1, RAPGEF5
|
0.002457 |
| Mucin type O.Glycan biosynthesis |
4 genes: GALNT13, GALNT10, WBSCR17, ST3GAL2
|
0.002637 |
| Glycosaminoglycan biosynthesis . keratan sulfate |
3 genes: ST3GAL2, CHST1, B3GNT7
|
0.002833 |
| Wnt signaling pathway |
9 genes: JUN, RHOA, NFATC1, NFATC4, PPP2CB, SFRP1, FZD4, FZD7, CCND3
|
0.002941 |
| SNARE interactions in vesicular transport |
4 genes: STX1B, STX2, VAMP1, VAMP2
|
0.00517 |
| Cell adhesion molecules .CAMs. |
8 genes: NFASC, ICOSLG, GLG1, NCAM1, CNTN2, CNTNAP1, CD4, NRXN2
|
0.005342 |
| Endocytosis |
10 genes: EHD1, DNM1, PIP5K1C, RAB11FIP5, EHD2, IGF1R, RHOA, PML, PSD, GIT2
|
0.006806 |
| Vascular smooth muscle contraction |
7 genes: RAMP3, GNA11, GNA12, ITPR2, KCNMA1, RHOA, PPP1R12A
|
0.007811 |
| Aldosterone.regulated sodium reabsorption |
4 genes: IGF1, NR3C2, ATP1B2, FXYD2
|
0.008965 |
| Neurotrophin signaling pathway |
7 genes: SH2B3, FOXO3, JUN, RHOA, NTRK2, NTRK3, MAPK12
|
0.0125 |
| T cell receptor signaling pathway |
6 genes: JUN, RHOA, NFATC1, NFATC4, MAPK12, CD4
|
0.01941 |
| Regulation of actin cytoskeleton |
9 genes: CFL2, PIP5K1C, GNA12, RHOA, PPP1R12A, ARHGEF4, PDGFB, VCL, ITGA10
|
0.02532 |
| ECM.receptor interaction |
5 genes: COL5A3, THBS1, ITGA10, CD47, SV2B
|
0.02557 |
| Leukocyte transendothelial migration |
6 genes: PTK2B, GNAI2, RHOA, MAPK12, THY1, VCL
|
0.02748 |
| Salivary secretion |
5 genes: ITPR2, KCNMA1, ATP1B2, FXYD2, VAMP2
|
0.0304 |
| Chemokine signaling pathway |
8 genes: RASGRP2, PTK2B, FOXO3, GNAI2, GNG4, GNG7, RHOA, CX3CL1
|
0.03279 |
| MAPK signaling pathway |
10 genes: RASGRP2, GNA12, JUN, MEF2C, NFATC4, NTRK2, PDGFB, MAPK12, PTPN5, MAPK8IP1
|
0.03868 |
| Phenylalanine metabolism |
2 genes: ALDH3B1, AOC3
|
0.04273 |
| PPAR signaling pathway |
4 genes: ILK, SLC27A1, PPARA, ADIPOQ
|
0.04818 |
| GnRH signaling pathway |
5 genes: PTK2B, GNA11, ITPR2, JUN, MAPK12
|
0.04818 |
| Pancreatic secretion |
5 genes: ITPR2, KCNMA1, RHOA, ATP1B2, FXYD2
|
0.04818 |