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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-362-3p ABCA1 0.11 0.64379 -0.05 0.8308 miRanda -0.27 0 NA
2 hsa-miR-362-3p ABCA6 0.11 0.64379 -0.41 0.30457 miRanda -0.49 1.0E-5 NA
3 hsa-miR-362-3p ABCC9 0.11 0.64379 -0.58 0.0487 miRanda -0.5 0 NA
4 hsa-miR-362-3p ABCD2 0.11 0.64379 -0.21 0.52359 miRanda -0.3 0.00143 NA
5 hsa-miR-362-3p ACAN 0.11 0.64379 -0.41 0.10954 miRanda -0.17 0.02006 NA
6 hsa-miR-362-3p ACER2 0.11 0.64379 -0.48 0.01435 miRanda -0.19 0.00079 NA
7 hsa-miR-362-3p ADAM28 0.11 0.64379 -0.48 0.15863 PITA -0.24 0.01584 NA
8 hsa-miR-362-3p ADAM33 0.11 0.64379 -0.33 0.4232 miRanda -0.41 0.0005 NA
9 hsa-miR-362-3p ADAMTS1 0.11 0.64379 -0.39 0.09809 miRanda -0.3 0 NA
10 hsa-miR-362-3p ADAMTS4 0.11 0.64379 -0.28 0.27653 miRanda -0.23 0.00078 NA
11 hsa-miR-362-3p ADAMTSL1 0.11 0.64379 -0.13 0.64223 miRanda -0.33 7.0E-5 NA
12 hsa-miR-362-3p ADAMTSL4 0.11 0.64379 -0.41 0.09478 miRNATAP -0.24 0.00059 NA
13 hsa-miR-362-3p ADCY1 0.11 0.64379 -0.69 0.01679 miRanda -0.32 0.00014 NA
14 hsa-miR-362-3p ADCYAP1 0.11 0.64379 -0.2 0.67185 miRanda -0.63 0 NA
15 hsa-miR-362-3p ADD2 0.11 0.64379 -0.98 0.01735 PITA; miRanda -0.55 0 NA
16 hsa-miR-362-3p AFF4 0.11 0.64379 -0.05 0.75124 PITA -0.12 0 NA
17 hsa-miR-362-3p AGAP11 0.11 0.64379 -0.07 0.78145 miRanda -0.18 0.01802 NA
18 hsa-miR-362-3p AGPAT4 0.11 0.64379 -0.78 0.00264 MirTarget -0.32 1.0E-5 NA
19 hsa-miR-362-3p AHNAK 0.11 0.64379 -0.62 0.01795 PITA; miRanda; miRNATAP -0.22 3.0E-5 NA
20 hsa-miR-362-3p AK5 0.11 0.64379 -0.8 0.01153 miRanda -0.35 0.00012 NA
21 hsa-miR-362-3p AKAP2 0.11 0.64379 0.17 0.40729 PITA; miRNATAP -0.25 1.0E-5 NA
22 hsa-miR-362-3p AKT3 0.11 0.64379 -0.59 0.01641 miRanda -0.42 0 NA
23 hsa-miR-362-3p ALCAM 0.11 0.64379 -0.18 0.41514 miRanda -0.1 0.04247 NA
24 hsa-miR-362-3p ALDH1A2 0.11 0.64379 -1.71 0.00293 miRanda -0.4 0.02021 NA
25 hsa-miR-362-3p AMOTL1 0.11 0.64379 -0.76 0.00615 MirTarget -0.45 0 NA
26 hsa-miR-362-3p ANGPTL2 0.11 0.64379 -0.63 0.02845 miRanda; miRNATAP -0.44 0 NA
27 hsa-miR-362-3p ANKRD44 0.11 0.64379 -0.5 0.04561 miRanda -0.23 0.00135 NA
28 hsa-miR-362-3p ANKRD6 0.11 0.64379 -0.33 0.13971 miRanda -0.2 0.00215 NA
29 hsa-miR-362-3p ANO1 0.11 0.64379 -1.17 0.00028 miRanda -0.27 0.00287 NA
30 hsa-miR-362-3p AP4S1 0.11 0.64379 -0.09 0.55098 miRanda -0.12 0.00739 NA
31 hsa-miR-362-3p APBA2 0.11 0.64379 -0.62 0.01322 miRanda; miRNATAP -0.28 9.0E-5 NA
32 hsa-miR-362-3p APBB1IP 0.11 0.64379 -0.53 0.06348 miRanda -0.33 8.0E-5 NA
33 hsa-miR-362-3p APOOL 0.11 0.64379 0.18 0.28233 miRanda -0.13 0.00821 NA
34 hsa-miR-362-3p AR 0.11 0.64379 -0.72 0.08465 miRanda -0.59 0 NA
35 hsa-miR-362-3p ARHGEF15 0.11 0.64379 -0.54 0.00479 miRanda -0.22 5.0E-5 NA
36 hsa-miR-362-3p ARHGEF6 0.11 0.64379 -0.48 0.03477 MirTarget; miRanda -0.32 0 NA
37 hsa-miR-362-3p ARL10 0.11 0.64379 -0.13 0.63188 mirMAP -0.33 1.0E-5 NA
38 hsa-miR-362-3p ARL4C 0.11 0.64379 -0.39 0.13323 PITA -0.32 0 NA
39 hsa-miR-362-3p ARL4D 0.11 0.64379 0.07 0.75696 miRNATAP -0.18 0.00433 NA
40 hsa-miR-362-3p ARMC9 0.11 0.64379 -0.32 0.03253 miRanda -0.12 0.00121 NA
41 hsa-miR-362-3p ARNT2 0.11 0.64379 -0.83 0.01329 miRanda -0.36 0.0002 NA
42 hsa-miR-362-3p ASAP1 0.11 0.64379 0.16 0.3669 miRanda -0.11 0.00754 NA
43 hsa-miR-362-3p ASXL2 0.11 0.64379 -0.01 0.96811 miRanda -0.16 3.0E-5 NA
44 hsa-miR-362-3p ATP10A 0.11 0.64379 -0.48 0.07791 miRanda -0.39 0 NA
45 hsa-miR-362-3p ATXN1 0.11 0.64379 -0.19 0.22524 MirTarget; PITA; miRanda; miRNATAP -0.15 0 NA
46 hsa-miR-362-3p B3GALT1 0.11 0.64379 -0.92 0.05694 miRanda -0.34 0.01452 NA
47 hsa-miR-362-3p B3GNT9 0.11 0.64379 -0.42 0.00761 miRanda -0.11 0.00601 NA
48 hsa-miR-362-3p BAALC 0.11 0.64379 -0.56 0.07918 miRanda -0.44 0 NA
49 hsa-miR-362-3p BAHCC1 0.11 0.64379 -0.14 0.5649 PITA; miRanda -0.24 0.00056 NA
50 hsa-miR-362-3p BCL6 0.11 0.64379 -0.43 0.02067 miRanda -0.15 0.00147 NA
51 hsa-miR-362-3p BEND4 0.11 0.64379 -0.57 0.13158 miRanda -0.35 0.00126 NA
52 hsa-miR-362-3p BEX4 0.11 0.64379 -0.56 0.02756 miRanda -0.3 4.0E-5 NA
53 hsa-miR-362-3p BHLHE22 0.11 0.64379 -0.08 0.78042 miRanda -0.3 0.00045 NA
54 hsa-miR-362-3p BMF 0.11 0.64379 0.05 0.80648 PITA; miRanda; miRNATAP -0.11 0.03223 NA
55 hsa-miR-362-3p BMP6 0.11 0.64379 -0.95 0 miRanda -0.21 0.00048 NA
56 hsa-miR-362-3p BMPR1B 0.11 0.64379 -1.56 0.00021 MirTarget; miRanda -0.58 0 NA
57 hsa-miR-362-3p BMPR2 0.11 0.64379 -0.08 0.64874 MirTarget; PITA; miRanda; miRNATAP -0.15 1.0E-5 NA
58 hsa-miR-362-3p BTK 0.11 0.64379 -0.56 0.06441 miRanda -0.37 3.0E-5 NA
59 hsa-miR-362-3p CACNA1B 0.11 0.64379 -1.82 0.00013 MirTarget; miRNATAP -0.39 0.00442 NA
60 hsa-miR-362-3p CACNA2D1 0.11 0.64379 -0.85 0.05575 miRanda -0.78 0 NA
61 hsa-miR-362-3p CADM1 0.11 0.64379 -0.57 0.06122 PITA; miRanda; miRNATAP -0.41 0 NA
62 hsa-miR-362-3p CADM3 0.11 0.64379 -0.5 0.33965 miRanda -0.76 0 NA
63 hsa-miR-362-3p CALCRL 0.11 0.64379 -0.45 0.04092 miRanda -0.33 0 NA
64 hsa-miR-362-3p CAMK2B 0.11 0.64379 -0.01 0.97166 miRanda -0.39 0.00026 NA
65 hsa-miR-362-3p CAMK4 0.11 0.64379 -0.8 0.0051 miRanda -0.25 0.00198 NA
66 hsa-miR-362-3p CAPN14 0.11 0.64379 -0.42 0.33347 miRanda -0.27 0.02922 NA
67 hsa-miR-362-3p CASS4 0.11 0.64379 -0.55 0.04983 miRanda -0.32 7.0E-5 NA
68 hsa-miR-362-3p CBLN2 0.11 0.64379 0.33 0.35314 miRanda -0.2 0.04895 NA
69 hsa-miR-362-3p CBX6 0.11 0.64379 -0.16 0.54398 mirMAP -0.3 0.00011 NA
70 hsa-miR-362-3p CC2D2A 0.11 0.64379 0.14 0.60106 miRanda -0.25 0.00089 NA
71 hsa-miR-362-3p CCDC102B 0.11 0.64379 -0.36 0.06947 miRanda -0.18 0.00154 NA
72 hsa-miR-362-3p CCDC85A 0.11 0.64379 -0.26 0.35716 miRanda; miRNATAP -0.37 1.0E-5 NA
73 hsa-miR-362-3p CCDC89 0.11 0.64379 -0.04 0.849 miRanda -0.16 0.01666 NA
74 hsa-miR-362-3p CCL19 0.11 0.64379 -0.2 0.71713 miRanda -0.49 0.00241 NA
75 hsa-miR-362-3p CCNJL 0.11 0.64379 -0.46 0.06809 miRanda -0.22 0.00205 NA
76 hsa-miR-362-3p CCPG1 0.11 0.64379 -0.39 0.02629 miRanda -0.12 0.00048 NA
77 hsa-miR-362-3p CD36 0.11 0.64379 -0.56 0.10855 miRanda -0.36 0.00049 NA
78 hsa-miR-362-3p CD79B 0.11 0.64379 -0.28 0.39374 PITA; miRanda -0.22 0.02274 NA
79 hsa-miR-362-3p CDH11 0.11 0.64379 -0.86 0.00288 miRanda -0.43 0 NA
80 hsa-miR-362-3p CDH13 0.11 0.64379 -0.45 0.02591 MirTarget; miRanda -0.19 0.0004 NA
81 hsa-miR-362-3p CDYL2 0.11 0.64379 -0.42 0.08783 miRanda -0.28 8.0E-5 NA
82 hsa-miR-362-3p CFH 0.11 0.64379 -0.52 0.05574 miRanda -0.42 0 NA
83 hsa-miR-362-3p CHL1 0.11 0.64379 -0.75 0.06297 miRanda -0.61 0 NA
84 hsa-miR-362-3p CHRDL1 0.11 0.64379 -0.12 0.84302 PITA; miRanda; miRNATAP -0.88 0 NA
85 hsa-miR-362-3p CLCF1 0.11 0.64379 -0.01 0.94286 miRanda -0.14 0.00726 NA
86 hsa-miR-362-3p CLIP4 0.11 0.64379 -0.43 0.14009 miRanda -0.48 0 NA
87 hsa-miR-362-3p CLU 0.11 0.64379 0.02 0.95834 miRanda -0.22 0.019 NA
88 hsa-miR-362-3p CMTM3 0.11 0.64379 -0.4 0.05724 miRanda -0.29 0 NA
89 hsa-miR-362-3p CNNM1 0.11 0.64379 0.03 0.92696 miRanda -0.38 0.00015 NA
90 hsa-miR-362-3p CNPY4 0.11 0.64379 -0.17 0.22383 miRanda -0.12 0.00044 NA
91 hsa-miR-362-3p CNR1 0.11 0.64379 -0.02 0.96823 miRanda -0.66 0 NA
92 hsa-miR-362-3p COL11A1 0.11 0.64379 -1.04 0.02407 miRanda -0.63 0 NA
93 hsa-miR-362-3p COL13A1 0.11 0.64379 -0.36 0.15915 miRanda -0.15 0.04683 NA
94 hsa-miR-362-3p COL24A1 0.11 0.64379 -1.04 0.00275 miRanda -0.53 0 NA
95 hsa-miR-362-3p COL4A1 0.11 0.64379 -0.46 0.06991 miRanda -0.23 1.0E-5 NA
96 hsa-miR-362-3p COL5A3 0.11 0.64379 -0.29 0.25685 miRanda -0.19 0.00776 NA
97 hsa-miR-362-3p COL6A3 0.11 0.64379 -0.68 0.04435 miRanda -0.42 0 NA
98 hsa-miR-362-3p CORIN 0.11 0.64379 -0.51 0.16112 miRanda -0.43 5.0E-5 NA
99 hsa-miR-362-3p CPEB4 0.11 0.64379 -0.14 0.38436 PITA; miRanda; miRNATAP -0.17 0 NA
100 hsa-miR-362-3p CR2 0.11 0.64379 -0.52 0.38404 miRanda -0.4 0.02325 NA
101 hsa-miR-362-3p CREB5 0.11 0.64379 0.1 0.71971 PITA -0.25 0.00256 NA
102 hsa-miR-362-3p CRIP2 0.11 0.64379 -0.59 0.00305 miRanda -0.22 1.0E-5 NA
103 hsa-miR-362-3p CRK 0.11 0.64379 -0.35 0.02694 miRanda -0.12 0.00011 NA
104 hsa-miR-362-3p CRMP1 0.11 0.64379 -0.15 0.5174 MirTarget; PITA; miRanda; miRNATAP -0.33 0 NA
105 hsa-miR-362-3p CSGALNACT1 0.11 0.64379 -0.38 0.07842 miRanda -0.2 0.00133 NA
106 hsa-miR-362-3p CX3CR1 0.11 0.64379 -0.11 0.7119 miRanda -0.36 2.0E-5 NA
107 hsa-miR-362-3p CXCL12 0.11 0.64379 -0.53 0.05256 miRanda -0.29 0.00013 NA
108 hsa-miR-362-3p CXCL6 0.11 0.64379 -0.01 0.97986 miRanda -0.26 0.02983 NA
109 hsa-miR-362-3p CXCR1 0.11 0.64379 -0.72 0.11406 miRanda -0.37 0.00538 NA
110 hsa-miR-362-3p CYP26B1 0.11 0.64379 -0.82 0.00608 miRanda -0.26 0.00362 NA
111 hsa-miR-362-3p CYTH4 0.11 0.64379 -0.65 0.0106 miRanda -0.27 0.00023 NA
112 hsa-miR-362-3p DAAM1 0.11 0.64379 -0.28 0.04584 MirTarget; miRanda; miRNATAP -0.16 1.0E-5 NA
113 hsa-miR-362-3p DACT1 0.11 0.64379 -0.88 0.00156 miRanda -0.32 4.0E-5 NA
114 hsa-miR-362-3p DAPK1 0.11 0.64379 -1.39 1.0E-5 PITA; miRanda; miRNATAP -0.23 0.01432 NA
115 hsa-miR-362-3p DCLK1 0.11 0.64379 -0.52 0.16756 miRanda -0.59 0 NA
116 hsa-miR-362-3p DCLK2 0.11 0.64379 -0.72 0.00239 miRanda -0.31 1.0E-5 NA
117 hsa-miR-362-3p DENND5A 0.11 0.64379 -0.27 0.13541 miRanda -0.2 1.0E-5 NA
118 hsa-miR-362-3p DFNA5 0.11 0.64379 -0.65 0.01802 miRanda -0.41 0 NA
119 hsa-miR-362-3p DISC1 0.11 0.64379 -0.39 0.02323 miRanda -0.19 0.00015 NA
120 hsa-miR-362-3p DKK3 0.11 0.64379 -0.46 0.04838 miRanda -0.32 0 NA
121 hsa-miR-362-3p DLC1 0.11 0.64379 -0.42 0.0471 miRanda -0.29 0 NA
122 hsa-miR-362-3p DMPK 0.11 0.64379 -0.27 0.10001 miRanda -0.12 0.00181 NA
123 hsa-miR-362-3p DNM3 0.11 0.64379 0.41 0.1412 MirTarget; PITA; miRanda; miRNATAP -0.16 0.0459 NA
124 hsa-miR-362-3p DOK6 0.11 0.64379 -0.35 0.17852 miRNATAP -0.43 0 NA
125 hsa-miR-362-3p DPP10 0.11 0.64379 -0.38 0.52965 miRanda -0.46 0.00855 NA
126 hsa-miR-362-3p DPYD 0.11 0.64379 -0.92 0.00346 miRanda -0.43 0 NA
127 hsa-miR-362-3p DPYSL3 0.11 0.64379 -0.83 0.0062 PITA; miRanda; miRNATAP -0.62 0 NA
128 hsa-miR-362-3p DTNA 0.11 0.64379 -0.6 0.13401 PITA; miRanda; miRNATAP -0.58 0 NA
129 hsa-miR-362-3p DTX1 0.11 0.64379 -0.44 0.05658 miRNATAP -0.14 0.03937 NA
130 hsa-miR-362-3p DZIP1 0.11 0.64379 -0.41 0.08969 miRanda -0.39 0 NA
131 hsa-miR-362-3p EDNRA 0.11 0.64379 0.08 0.76309 miRanda -0.35 0 NA
132 hsa-miR-362-3p EFNA5 0.11 0.64379 -1.18 0.00241 miRanda -0.43 0.00017 NA
133 hsa-miR-362-3p EGFLAM 0.11 0.64379 -0.37 0.0797 MirTarget; miRanda; miRNATAP -0.21 0.0008 NA
134 hsa-miR-362-3p EGR3 0.11 0.64379 -0.66 0.03342 miRanda -0.26 0.00372 NA
135 hsa-miR-362-3p ELAVL2 0.11 0.64379 0.58 0.25933 miRanda -0.45 0.00289 NA
136 hsa-miR-362-3p ELOVL4 0.11 0.64379 -0.4 0.09604 miRanda -0.41 0 NA
137 hsa-miR-362-3p ENPP6 0.11 0.64379 -0.6 0.04536 MirTarget; miRanda -0.18 0.03197 NA
138 hsa-miR-362-3p EPB41L3 0.11 0.64379 -0.66 0.04938 PITA; miRanda -0.45 0 NA
139 hsa-miR-362-3p EPHA3 0.11 0.64379 -0.12 0.69472 miRanda -0.45 0 NA
140 hsa-miR-362-3p EPHA4 0.11 0.64379 -1.32 0.00041 PITA; miRanda; miRNATAP -0.4 0.00024 NA
141 hsa-miR-362-3p EPHA7 0.11 0.64379 -0.47 0.28753 miRanda -0.55 2.0E-5 NA
142 hsa-miR-362-3p ETS1 0.11 0.64379 -0.48 0.02266 miRanda -0.27 0 NA
143 hsa-miR-362-3p EVI2A 0.11 0.64379 -0.53 0.0452 miRanda -0.33 1.0E-5 NA
144 hsa-miR-362-3p EXOC3L2 0.11 0.64379 -0.28 0.0604 miRanda -0.13 0.00303 NA
145 hsa-miR-362-3p FAM126A 0.11 0.64379 -0.14 0.52106 miRanda -0.21 0.0012 NA
146 hsa-miR-362-3p FAM129A 0.11 0.64379 -0.52 0.05188 miRanda -0.46 0 NA
147 hsa-miR-362-3p FAM184A 0.11 0.64379 -0.26 0.4994 miRanda -0.34 0.00274 NA
148 hsa-miR-362-3p FAM198A 0.11 0.64379 -0.5 0.1875 miRanda -0.46 3.0E-5 NA
149 hsa-miR-362-3p FAM43B 0.11 0.64379 -0.6 0.11717 miRanda -0.55 0 NA
150 hsa-miR-362-3p FAT3 0.11 0.64379 -0.12 0.71946 MirTarget; miRanda -0.47 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 103 1672 9.584e-20 4.46e-16
2 REGULATION OF CELL DIFFERENTIATION 93 1492 4.107e-18 9.556e-15
3 NEUROGENESIS 88 1402 2.572e-17 3.989e-14
4 CELL DEVELOPMENT 87 1426 2.269e-16 2.64e-13
5 CARDIOVASCULAR SYSTEM DEVELOPMENT 58 788 1.79e-14 1.235e-11
6 REGULATION OF CELL DEVELOPMENT 60 836 1.859e-14 1.235e-11
7 CIRCULATORY SYSTEM DEVELOPMENT 58 788 1.79e-14 1.235e-11
8 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 55 750 1.057e-13 6.146e-11
9 REGULATION OF NEURON DIFFERENTIATION 46 554 1.637e-13 8.461e-11
10 POSITIVE REGULATION OF CELL DIFFERENTIATION 57 823 3.958e-13 1.842e-10
11 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 69 1142 7.353e-13 3.11e-10
12 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 78 1395 1.017e-12 3.945e-10
13 VASCULATURE DEVELOPMENT 40 469 2.938e-12 1.052e-09
14 CELLULAR COMPONENT MORPHOGENESIS 57 900 1.47e-11 4.886e-09
15 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 59 957 1.851e-11 5.677e-09
16 ANGIOGENESIS 30 293 1.952e-11 5.677e-09
17 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 61 1021 2.959e-11 8.098e-09
18 BLOOD VESSEL MORPHOGENESIS 33 364 5.084e-11 1.314e-08
19 TISSUE DEVELOPMENT 78 1518 6.568e-11 1.608e-08
20 REGULATION OF NEURON PROJECTION DEVELOPMENT 34 408 2.489e-10 5.792e-08
21 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 87 1848 3.832e-10 8.042e-08
22 NEURON DIFFERENTIATION 53 874 3.928e-10 8.042e-08
23 REGULATION OF CELLULAR COMPONENT MOVEMENT 49 771 3.975e-10 8.042e-08
24 TAXIS 36 464 5.244e-10 1.017e-07
25 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 38 513 6.374e-10 1.186e-07
26 LOCOMOTION 61 1114 9.516e-10 1.703e-07
27 CELL PROJECTION ORGANIZATION 53 902 1.198e-09 2.065e-07
28 REGULATION OF CELL MORPHOGENESIS 39 552 1.457e-09 2.421e-07
29 RESPONSE TO ENDOGENOUS STIMULUS 72 1450 1.781e-09 2.857e-07
30 POSITIVE REGULATION OF CELL PROLIFERATION 49 814 2.426e-09 3.762e-07
31 REGULATION OF CELL PROLIFERATION 73 1496 2.855e-09 4.286e-07
32 RESPONSE TO EXTERNAL STIMULUS 83 1821 4.834e-09 7.03e-07
33 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 33 437 5.526e-09 7.563e-07
34 RESPONSE TO LIPID 51 888 5.428e-09 7.563e-07
35 NEURON DEVELOPMENT 43 687 7.916e-09 1.052e-06
36 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 81 1784 9.164e-09 1.184e-06
37 POSITIVE REGULATION OF CELL DEVELOPMENT 34 472 1.057e-08 1.329e-06
38 REGULATION OF CELL ADHESION 40 629 1.75e-08 2.105e-06
39 BIOLOGICAL ADHESION 55 1032 1.765e-08 2.105e-06
40 REGULATION OF CELL PROJECTION ORGANIZATION 37 558 2.094e-08 2.435e-06
41 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 53 983 2.243e-08 2.545e-06
42 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 63 1275 2.553e-08 2.828e-06
43 REGULATION OF HOMEOSTATIC PROCESS 32 447 3.349e-08 3.624e-06
44 NEURON PROJECTION MORPHOGENESIS 30 402 3.62e-08 3.828e-06
45 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 27 337 4.142e-08 4.1e-06
46 RESPONSE TO ORGANIC CYCLIC COMPOUND 50 917 4.082e-08 4.1e-06
47 REGULATION OF CELL DEATH 69 1472 4.083e-08 4.1e-06
48 CELL PART MORPHOGENESIS 39 633 6.175e-08 5.986e-06
49 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 14 98 7.922e-08 7.523e-06
50 POSITIVE REGULATION OF NEURON DIFFERENTIATION 25 306 9.071e-08 8.358e-06
51 REGULATION OF EPITHELIAL CELL PROLIFERATION 24 285 9.341e-08 8.358e-06
52 BEHAVIOR 34 516 9.271e-08 8.358e-06
53 NEURON PROJECTION DEVELOPMENT 35 545 1.116e-07 9.793e-06
54 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 64 1360 1.177e-07 1.014e-05
55 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 53 1036 1.233e-07 1.024e-05
56 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 53 1036 1.233e-07 1.024e-05
57 POSITIVE REGULATION OF CELL DEATH 37 605 1.641e-07 1.339e-05
58 REGULATION OF MAPK CASCADE 39 660 1.832e-07 1.47e-05
59 MULTI MULTICELLULAR ORGANISM PROCESS 20 213 1.936e-07 1.501e-05
60 REGULATION OF SYSTEM PROCESS 33 507 1.91e-07 1.501e-05
61 RESPONSE TO OXYGEN CONTAINING COMPOUND 64 1381 2.039e-07 1.555e-05
62 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 27 368 2.476e-07 1.858e-05
63 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 51 1008 3.047e-07 2.246e-05
64 EXTRACELLULAR STRUCTURE ORGANIZATION 24 304 3.09e-07 2.246e-05
65 POSITIVE REGULATION OF LOCOMOTION 29 420 3.184e-07 2.28e-05
66 CENTRAL NERVOUS SYSTEM DEVELOPMENT 46 872 3.793e-07 2.674e-05
67 SKELETAL SYSTEM DEVELOPMENT 30 455 5.302e-07 3.682e-05
68 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 11 68 5.466e-07 3.74e-05
69 REGULATION OF AXONOGENESIS 17 168 5.586e-07 3.767e-05
70 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 76 1805 6e-07 3.988e-05
71 CELL MOTILITY 44 835 7.103e-07 4.528e-05
72 REGULATION OF DENDRITIC SPINE DEVELOPMENT 10 56 6.952e-07 4.528e-05
73 LOCALIZATION OF CELL 44 835 7.103e-07 4.528e-05
74 UROGENITAL SYSTEM DEVELOPMENT 23 299 8.575e-07 5.392e-05
75 INTRACELLULAR SIGNAL TRANSDUCTION 68 1572 1.006e-06 6.24e-05
76 POSITIVE REGULATION OF MAPK CASCADE 30 470 1.042e-06 6.38e-05
77 PROTEIN PHOSPHORYLATION 47 944 1.432e-06 8.655e-05
78 REGULATION OF CHEMOTAXIS 17 180 1.473e-06 8.784e-05
79 LOCOMOTORY BEHAVIOR 17 181 1.59e-06 9.366e-05
80 ORGAN MORPHOGENESIS 43 841 2.093e-06 0.0001217
81 HEART DEVELOPMENT 29 466 2.611e-06 0.00015
82 CELL CELL SIGNALING 40 767 2.995e-06 0.0001699
83 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 19 232 3.085e-06 0.0001709
84 NEGATIVE CHEMOTAXIS 8 39 3.074e-06 0.0001709
85 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 17 191 3.328e-06 0.0001822
86 EPITHELIUM DEVELOPMENT 46 945 3.407e-06 0.0001822
87 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 48 1004 3.374e-06 0.0001822
88 REGULATION OF CELL SIZE 16 172 3.644e-06 0.0001927
89 NEGATIVE REGULATION OF CELL DEVELOPMENT 22 303 3.82e-06 0.0001975
90 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 22 303 3.82e-06 0.0001975
91 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 52 1135 4.392e-06 0.0002246
92 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 17 197 5.057e-06 0.0002451
93 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 20 262 4.978e-06 0.0002451
94 REGULATION OF CELL CELL ADHESION 25 380 4.917e-06 0.0002451
95 REGULATION OF EXTENT OF CELL GROWTH 12 101 4.931e-06 0.0002451
96 NEGATIVE REGULATION OF CELL PROLIFERATION 35 643 5.037e-06 0.0002451
97 REGULATION OF PHOSPHORUS METABOLIC PROCESS 67 1618 5.405e-06 0.0002593
98 REGULATION OF ION TRANSPORT 33 592 5.749e-06 0.000273
99 RESPONSE TO ALCOHOL 24 362 6.674e-06 0.0003137
100 HEAD DEVELOPMENT 37 709 7.013e-06 0.0003263
101 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 28 465 7.23e-06 0.0003331
102 POSITIVE REGULATION OF GENE EXPRESSION 70 1733 7.571e-06 0.0003454
103 DIVALENT INORGANIC CATION HOMEOSTASIS 23 343 8.623e-06 0.0003785
104 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 40 801 8.419e-06 0.0003785
105 NEURON PROJECTION GUIDANCE 17 205 8.604e-06 0.0003785
106 REGULATION OF BLOOD CIRCULATION 21 295 8.576e-06 0.0003785
107 REGULATION OF SEQUESTERING OF CALCIUM ION 12 107 9.018e-06 0.0003922
108 REGULATION OF CELL MATRIX ADHESION 11 90 9.279e-06 0.0003998
109 REGULATION OF HYDROLASE ACTIVITY 57 1327 1.026e-05 0.0004373
110 NEGATIVE REGULATION OF CELL DIFFERENTIATION 33 609 1.034e-05 0.0004373
111 SENSORY PERCEPTION OF PAIN 10 75 1.082e-05 0.0004536
112 REGULATION OF CALCIUM ION TRANSPORT 17 209 1.11e-05 0.000459
113 SYNAPTIC SIGNALING 26 424 1.117e-05 0.000459
114 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 9 60 1.125e-05 0.000459
115 REGULATION OF METAL ION TRANSPORT 22 325 1.165e-05 0.0004713
116 TISSUE MORPHOGENESIS 30 533 1.276e-05 0.0005116
117 STEM CELL DIFFERENTIATION 16 190 1.301e-05 0.0005173
118 POSITIVE REGULATION OF RESPONSE TO STIMULUS 75 1929 1.312e-05 0.0005175
119 POSITIVE REGULATION OF CELL COMMUNICATION 63 1532 1.325e-05 0.0005181
120 REGULATION OF GTPASE ACTIVITY 35 673 1.342e-05 0.0005204
121 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 25 404 1.411e-05 0.0005425
122 CELLULAR RESPONSE TO LIPID 27 457 1.479e-05 0.0005641
123 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 17 216 1.707e-05 0.0006459
124 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 37 740 1.801e-05 0.000676
125 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 14 154 1.907e-05 0.00071
126 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 13 135 2.043e-05 0.0007546
127 REGULATION OF DEVELOPMENTAL GROWTH 20 289 2.109e-05 0.0007726
128 EMBRYO DEVELOPMENT 42 894 2.15e-05 0.0007817
129 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 66 1656 2.179e-05 0.0007837
130 BONE DEVELOPMENT 14 156 2.206e-05 0.0007837
131 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 61 1492 2.193e-05 0.0007837
132 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 43 926 2.256e-05 0.0007953
133 REGULATION OF HEART CONTRACTION 17 221 2.295e-05 0.0008028
134 CIRCULATORY SYSTEM PROCESS 23 366 2.435e-05 0.0008406
135 RESPONSE TO STEROID HORMONE 28 497 2.439e-05 0.0008406
136 TUBE DEVELOPMENT 30 552 2.475e-05 0.0008468
137 CELL CELL ADHESION 32 608 2.502e-05 0.0008497
138 REGULATION OF JNK CASCADE 14 159 2.732e-05 0.0009212
139 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 9 67 2.808e-05 0.0009401
140 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 20 296 2.97e-05 0.0009627
141 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 41 876 2.944e-05 0.0009627
142 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 16 203 2.954e-05 0.0009627
143 REGULATION OF DENDRITE DEVELOPMENT 12 120 2.905e-05 0.0009627
144 POSITIVE REGULATION OF OSSIFICATION 10 84 2.979e-05 0.0009627
145 REGULATION OF PROTEIN MODIFICATION PROCESS 67 1710 3.197e-05 0.001026
146 CELL CHEMOTAXIS 14 162 3.365e-05 0.001047
147 RESPONSE TO INORGANIC SUBSTANCE 27 479 3.371e-05 0.001047
148 CYTOSOLIC CALCIUM ION TRANSPORT 8 53 3.31e-05 0.001047
149 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 11 103 3.374e-05 0.001047
150 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 19 274 3.285e-05 0.001047
151 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 15 184 3.528e-05 0.001087
152 POSITIVE REGULATION OF CELL ADHESION 23 376 3.707e-05 0.001135
153 POSITIVE REGULATION OF KINASE ACTIVITY 27 482 3.754e-05 0.001142
154 POSITIVE REGULATION OF MOLECULAR FUNCTION 69 1791 4.092e-05 0.001236
155 POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE 6 28 4.201e-05 0.001261
156 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 17 232 4.256e-05 0.00127
157 RESPONSE TO HORMONE 41 893 4.54e-05 0.001346
158 ENDOTHELIAL CELL DIFFERENTIATION 9 72 5.034e-05 0.001483
159 SINGLE ORGANISM BEHAVIOR 23 384 5.126e-05 0.001491
160 REGULATION OF TRANSPORT 69 1804 5.125e-05 0.001491
161 CALCIUM ION TRANSMEMBRANE IMPORT INTO CYTOSOL 7 42 5.357e-05 0.001539
162 CALCIUM ION IMPORT INTO CYTOSOL 7 42 5.357e-05 0.001539
163 REGULATION OF GROWTH 32 633 5.424e-05 0.001543
164 ENDOTHELIUM DEVELOPMENT 10 90 5.439e-05 0.001543
165 SENSORY ORGAN DEVELOPMENT 27 493 5.517e-05 0.001556
166 LEUKOCYTE ACTIVATION 24 414 5.921e-05 0.00165
167 EPITHELIAL CELL DIFFERENTIATION 27 495 5.908e-05 0.00165
168 REGULATION OF ACUTE INFLAMMATORY RESPONSE 9 74 6.269e-05 0.001736
169 CONNECTIVE TISSUE DEVELOPMENT 15 194 6.487e-05 0.001786
170 CELL DEATH 44 1001 6.602e-05 0.001807
171 REGULATION OF CELL GROWTH 23 391 6.747e-05 0.001836
172 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 13 153 7.599e-05 0.002056
173 MATERNAL PLACENTA DEVELOPMENT 6 31 7.729e-05 0.002079
174 REGULATION OF SYNAPSE ORGANIZATION 11 113 7.952e-05 0.002114
175 REGULATION OF STEM CELL DIFFERENTIATION 11 113 7.952e-05 0.002114
176 RESPONSE TO ACID CHEMICAL 20 319 8.434e-05 0.00223
177 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 11 114 8.617e-05 0.002265
178 REGULATION OF FEVER GENERATION 4 11 9.08e-05 0.002374
179 RESPONSE TO CALCIUM ION 11 115 9.328e-05 0.002425
180 REGULATION OF OSSIFICATION 14 178 9.406e-05 0.002431
181 REGULATION OF ION HOMEOSTASIS 15 201 9.683e-05 0.002489
182 TUBE MORPHOGENESIS 20 323 9.996e-05 0.002555
183 CELL ACTIVATION 29 568 0.000102 0.002592
184 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 9 79 0.0001051 0.002659
185 CALCIUM ION TRANSMEMBRANE TRANSPORT 13 159 0.0001124 0.002828
186 REGULATION OF CARTILAGE DEVELOPMENT 8 63 0.0001176 0.002925
187 REGULATION OF CELL KILLING 8 63 0.0001176 0.002925
188 REGULATION OF JUN KINASE ACTIVITY 9 81 0.0001278 0.003164
189 NEGATIVE REGULATION OF CELL COMMUNICATION 49 1192 0.0001314 0.003234
190 RESPONSE TO FLUID SHEAR STRESS 6 34 0.0001329 0.003255
191 POSITIVE REGULATION OF CHEMOTAXIS 11 120 0.0001369 0.003334
192 RESPONSE TO METAL ION 20 333 0.0001507 0.003652
193 REGULATION OF RESPONSE TO WOUNDING 23 413 0.0001523 0.003672
194 IMMUNE SYSTEM DEVELOPMENT 29 582 0.0001547 0.00371
195 REGULATION OF CARDIAC CONDUCTION 8 66 0.0001639 0.00391
196 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 7 50 0.0001684 0.003998
197 REGULATION OF ADAPTIVE IMMUNE RESPONSE 11 123 0.0001705 0.004026
198 REGULATION OF EPITHELIAL CELL MIGRATION 13 166 0.0001732 0.004026
199 REGULATION OF ANATOMICAL STRUCTURE SIZE 25 472 0.0001739 0.004026
200 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 13 166 0.0001732 0.004026
201 REGULATION OF IMMUNE SYSTEM PROCESS 55 1403 0.0001718 0.004026
202 REGULATION OF CELLULAR COMPONENT SIZE 20 337 0.0001766 0.004049
203 RESPONSE TO OXYGEN LEVELS 19 311 0.0001762 0.004049
204 CARDIOBLAST DIFFERENTIATION 4 13 0.0001894 0.004321
205 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 36 799 0.0001917 0.004351
206 NEGATIVE REGULATION OF LOCOMOTION 17 263 0.0001971 0.004453
207 REGULATION OF HEMOPOIESIS 19 314 0.0001992 0.004477
208 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 10 106 0.0002162 0.004836
209 PEPTIDYL SERINE MODIFICATION 12 148 0.0002212 0.004911
210 POSITIVE REGULATION OF CATALYTIC ACTIVITY 58 1518 0.0002217 0.004911
211 EMBRYONIC MORPHOGENESIS 27 539 0.0002385 0.005234
212 REGULATION OF TRANSMEMBRANE TRANSPORT 23 426 0.0002385 0.005234
213 REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY 7 53 0.0002444 0.00534
214 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 8 70 0.000248 0.005391
215 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 6 38 0.0002518 0.005449
216 REGULATION OF CELL ACTIVATION 25 484 0.0002547 0.005487
217 CHEMICAL HOMEOSTASIS 38 874 0.0002597 0.005531
218 RESPONSE TO LOW DENSITY LIPOPROTEIN PARTICLE 4 14 0.0002602 0.005531
219 REGULATION OF CELL SUBSTRATE ADHESION 13 173 0.0002603 0.005531
220 PHOSPHORYLATION 49 1228 0.0002638 0.005579
221 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 33 724 0.0002876 0.006055
222 REGULATION OF AXON GUIDANCE 6 39 0.0002917 0.006086
223 MUSCLE STRUCTURE DEVELOPMENT 23 432 0.0002911 0.006086
224 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 11 131 0.0002964 0.006157
225 CALCIUM ION TRANSPORT 15 223 0.0003023 0.006251
226 AMEBOIDAL TYPE CELL MIGRATION 12 154 0.0003195 0.006552
227 EYE DEVELOPMENT 19 326 0.0003196 0.006552
228 SKELETAL SYSTEM MORPHOGENESIS 14 201 0.0003346 0.006829
229 REGULATION OF HEAT GENERATION 4 15 0.0003482 0.007076
230 OSSIFICATION 16 251 0.0003518 0.007117
231 MESENCHYMAL CELL DIFFERENTIATION 11 134 0.0003604 0.00726
232 OVULATION CYCLE 10 113 0.0003637 0.007295
233 CELL FATE COMMITMENT 15 227 0.0003653 0.007295
234 REGULATION OF ENDOTHELIAL CELL MIGRATION 10 114 0.0003904 0.00773
235 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 14 204 0.0003888 0.00773
236 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 8 75 0.0003997 0.00788
237 RESPONSE TO ABIOTIC STIMULUS 42 1024 0.0004202 0.00825
238 REGULATION OF HOMOTYPIC CELL CELL ADHESION 18 307 0.0004245 0.008299
239 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 37 867 0.0004449 0.008662
240 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 10 116 0.0004487 0.008699
241 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 4 16 0.0004557 0.008797
242 REGULATION OF LEUKOCYTE DIFFERENTIATION 15 232 0.0004597 0.008838
243 RESPONSE TO GROWTH FACTOR 24 475 0.0004621 0.008848
244 LEUKOCYTE CHEMOTAXIS 10 117 0.0004804 0.009125
245 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 7 59 0.0004788 0.009125
246 IMMUNE SYSTEM PROCESS 70 1984 0.0004919 0.009304
247 CELL JUNCTION ORGANIZATION 13 185 0.0004969 0.00936
248 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 12 162 0.0005061 0.009495
249 POSITIVE REGULATION OF HYDROLASE ACTIVITY 38 905 0.0005085 0.009502
250 REGULATION OF ACTIN FILAMENT BASED PROCESS 18 312 0.0005138 0.009562
251 CARDIAC MUSCLE TISSUE DEVELOPMENT 11 140 0.0005237 0.009708
252 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 7 60 0.0005311 0.009806
253 HEMATOPOIETIC PROGENITOR CELL DIFFERENTIATION 9 98 0.0005409 0.009948
NumGOOverlapSizeP ValueAdj. P Value
1 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 37 629 4.272e-07 0.0003969
2 SIGNAL TRANSDUCER ACTIVITY 71 1731 3.794e-06 0.001266
3 RECEPTOR BINDING 63 1476 4.09e-06 0.001266
4 PROTEIN KINASE ACTIVITY 33 640 2.814e-05 0.003839
5 GLYCOSAMINOGLYCAN BINDING 16 205 3.329e-05 0.003839
6 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 17 228 3.417e-05 0.003839
7 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 51 1199 4.01e-05 0.003839
8 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 20 303 4.132e-05 0.003839
9 CHEMOREPELLENT ACTIVITY 6 27 3.368e-05 0.003839
10 GROWTH FACTOR BINDING 12 123 3.717e-05 0.003839
11 REGULATORY REGION NUCLEIC ACID BINDING 38 818 6.782e-05 0.004707
12 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 20 315 7.093e-05 0.004707
13 RECEPTOR ACTIVITY 64 1649 6.485e-05 0.004707
14 RECEPTOR SIGNALING PROTEIN ACTIVITY 14 172 6.498e-05 0.004707
15 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 9 76 7.75e-05 0.0048
NumGOOverlapSizeP ValueAdj. P Value
1 SYNAPSE 47 754 1.738e-09 1.015e-06
2 NEURON PART 63 1265 1.906e-08 5.565e-06
3 NEURON PROJECTION 50 942 9.424e-08 1.835e-05
4 SYNAPSE PART 37 610 2.013e-07 2.939e-05
5 MEMBRANE REGION 54 1134 8.874e-07 0.0001037
6 EXTRACELLULAR MATRIX 27 426 4.134e-06 0.0002864
7 EXCITATORY SYNAPSE 17 197 5.057e-06 0.0002864
8 SECRETORY VESICLE 28 461 6.152e-06 0.0002864
9 POSTSYNAPSE 25 378 4.482e-06 0.0002864
10 CELL SURFACE 39 757 5.326e-06 0.0002864
11 MEMBRANE MICRODOMAIN 21 288 5.927e-06 0.0002864
12 CELL PROJECTION 73 1786 3.072e-06 0.0002864
13 SOMATODENDRITIC COMPARTMENT 35 650 6.375e-06 0.0002864
14 EXTRACELLULAR SPACE 59 1376 7.454e-06 0.000311
15 DENDRITE 27 451 1.168e-05 0.0004549
16 CELL JUNCTION 51 1151 1.365e-05 0.0004982
17 PROTEINACEOUS EXTRACELLULAR MATRIX 23 356 1.57e-05 0.0005394
18 INTRINSIC COMPONENT OF PLASMA MEMBRANE 66 1649 1.908e-05 0.0006191
19 CELL BODY 27 494 5.71e-05 0.001755
20 SECRETORY GRANULE 21 352 0.0001139 0.003326
21 EXOCYTIC VESICLE 12 142 0.00015 0.00417
22 PRESYNAPSE 18 283 0.0001579 0.00419
23 EXTERNAL SIDE OF PLASMA MEMBRANE 16 238 0.0001935 0.004709
24 DENSE CORE GRANULE 4 13 0.0001894 0.004709
25 RECEPTOR COMPLEX 19 327 0.0003321 0.007757

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cytokine_cytokine_receptor_interaction_hsa04060 18 270 8.736e-05 0.002437
2 Rap1_signaling_pathway_hsa04015 15 206 0.0001274 0.002437
3 ECM_receptor_interaction_hsa04512 9 82 0.0001406 0.002437
4 Hippo_signaling_pathway_hsa04390 12 154 0.0003195 0.003565
5 Apelin_signaling_pathway_hsa04371 11 137 0.0004357 0.003565
6 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 11 139 0.0004928 0.003565
7 cGMP_PKG_signaling_pathway_hsa04022 12 163 0.0005348 0.003565
8 Hippo_signaling_pathway_multiple_species_hsa04392 5 29 0.0005484 0.003565
9 cAMP_signaling_pathway_hsa04024 13 198 0.0009374 0.005416
10 Calcium_signaling_pathway_hsa04020 12 182 0.001403 0.007297
11 MAPK_signaling_pathway_hsa04010 16 295 0.001949 0.009215
12 Phospholipase_D_signaling_pathway_hsa04072 10 146 0.002599 0.01126
13 Gap_junction_hsa04540 7 88 0.004954 0.01982
14 Neuroactive_ligand_receptor_interaction_hsa04080 14 278 0.006921 0.02571
15 Cell_adhesion_molecules_.CAMs._hsa04514 9 145 0.007883 0.02667
16 Focal_adhesion_hsa04510 11 199 0.008205 0.02667
17 Ras_signaling_pathway_hsa04014 12 232 0.009775 0.0299
18 Regulation_of_actin_cytoskeleton_hsa04810 11 208 0.0112 0.03236
19 PI3K_Akt_signaling_pathway_hsa04151 15 352 0.02171 0.05652
20 ABC_transporters_hsa02010 4 45 0.02174 0.05652
21 NF_kappa_B_signaling_pathway_hsa04064 6 95 0.02569 0.06362
22 TGF_beta_signaling_pathway_hsa04350 5 84 0.04967 0.1174
23 Oocyte_meiosis_hsa04114 6 124 0.07545 0.1706
24 Cellular_senescence_hsa04218 7 160 0.08759 0.1898
25 Jak_STAT_signaling_pathway_hsa04630 7 162 0.09206 0.1915
26 Wnt_signaling_pathway_hsa04310 6 146 0.135 0.2699
27 ErbB_signaling_pathway_hsa04012 4 85 0.1437 0.2768
28 AMPK_signaling_pathway_hsa04152 5 121 0.1612 0.2955
29 VEGF_signaling_pathway_hsa04370 3 59 0.1648 0.2955
30 Autophagy_animal_hsa04140 5 128 0.189 0.3276
31 Notch_signaling_pathway_hsa04330 2 48 0.3162 0.5305
32 FoxO_signaling_pathway_hsa04068 4 132 0.3834 0.6231
33 Apoptosis_hsa04210 4 138 0.4156 0.6549
34 Mitophagy_animal_hsa04137 2 65 0.4591 0.7022
35 TNF_signaling_pathway_hsa04668 3 108 0.4748 0.7055
36 Endocytosis_hsa04144 6 244 0.5232 0.7545
37 Tight_junction_hsa04530 4 170 0.5771 0.7897
38 Phosphatidylinositol_signaling_system_hsa04070 2 99 0.6852 0.8658
39 HIF_1_signaling_pathway_hsa04066 2 100 0.6905 0.8658
40 mTOR_signaling_pathway_hsa04150 3 151 0.6993 0.8658
41 Sphingolipid_signaling_pathway_hsa04071 2 118 0.7739 0.9308
42 Lysosome_hsa04142 2 123 0.7933 0.9308
43 Phagosome_hsa04145 2 152 0.8793 0.9526
44 Necroptosis_hsa04217 2 164 0.9041 0.9594

Quest ID: 096eff70a64b463a51f81d67d81f45e7