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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-15b-5p AATK 0.25 0.79071 0 0.99243 MirTarget -0.22 0.04433 NA
2 hsa-miR-107 ABCA6 -0.29 0.76966 -0.01 0.98022 miRanda -0.39 0.00471 NA
3 hsa-miR-183-5p ABCA8 -0.05 0.96949 0.55 0.32098 MirTarget -0.22 0.0202 NA
4 hsa-miR-192-5p ABCA8 -0 0.99638 0.55 0.32098 miRNAWalker2 validate -0.44 2.0E-5 NA
5 hsa-miR-361-5p ABCA8 -0.28 0.72855 0.55 0.32098 miRanda -0.72 0.00086 NA
6 hsa-miR-375 ABCA8 -0.99 0.31273 0.55 0.32098 miRanda -0.15 0.02261 NA
7 hsa-miR-15b-5p ABCB5 0.25 0.79071 1.03 0.08206 MirTarget -0.37 0.02462 NA
8 hsa-miR-146b-5p ABCG2 0.03 0.96457 -0.35 0.22034 miRanda -0.1 0.04508 NA
9 hsa-miR-199b-5p ABCG2 0.42 0.32426 -0.35 0.22034 miRanda -0.14 0.00072 NA
10 hsa-miR-107 ABHD12B -0.29 0.76966 0.09 0.83255 miRanda -0.37 0.00148 NA
11 hsa-miR-107 ABHD13 -0.29 0.76966 0.09 0.82184 MirTarget; miRanda -0.11 0.00368 NA
12 hsa-miR-125a-5p ABHD6 -0.01 0.99489 0.1 0.72561 MirTarget; PITA; miRanda; miRNATAP -0.16 0.01347 NA
13 hsa-miR-21-3p ABI2 0.13 0.87791 -0.13 0.82172 MirTarget -0.13 0 NA
14 hsa-miR-23a-3p ABI2 0.17 0.86572 -0.13 0.82172 mirMAP -0.1 0.00625 NA
15 hsa-miR-342-3p ABI2 -0.23 0.73996 -0.13 0.82172 miRanda -0.15 3.0E-5 NA
16 hsa-miR-107 ABR -0.29 0.76966 -0.46 0.36774 miRanda -0.13 0.04074 NA
17 hsa-miR-222-3p ACACA -0.23 0.72665 -0.23 0.66735 miRNAWalker2 validate -0.1 0.00386 NA
18 hsa-miR-107 ACO1 -0.29 0.76966 0.01 0.982 miRanda -0.15 0.00127 NA
19 hsa-miR-107 ACTG2 -0.29 0.76966 0.62 0.28177 miRanda -0.33 0.02553 NA
20 hsa-miR-129-5p ACTG2 0.42 0.45424 0.62 0.28177 miRanda -0.18 0.01686 NA
21 hsa-miR-125a-5p ACTL6A -0.01 0.99489 -0.06 0.91712 miRanda -0.17 0.00237 NA
22 hsa-miR-140-3p ACVR2B -0.11 0.90778 -0.14 0.74032 miRNAWalker2 validate; PITA; miRNATAP -0.12 0.02438 NA
23 hsa-miR-15b-5p ACVR2B 0.25 0.79071 -0.14 0.74032 miRNATAP -0.28 0 NA
24 hsa-miR-221-3p ADAM11 -0.26 0.74402 -0.51 0.14444 miRNATAP -0.3 0.00022 NA
25 hsa-miR-222-3p ADAM11 -0.23 0.72665 -0.51 0.14444 miRNATAP -0.26 0.00147 NA
26 hsa-miR-221-3p ADAM22 -0.26 0.74402 0.36 0.38733 MirTarget; miRNATAP -0.36 0.00015 NA
27 hsa-miR-222-3p ADAM22 -0.23 0.72665 0.36 0.38733 MirTarget; miRNATAP -0.34 0.00039 NA
28 hsa-miR-197-3p ADAMTS1 0.02 0.98197 -0.26 0.69609 miRNATAP -0.2 0.04534 NA
29 hsa-miR-27a-3p ADAMTS10 0.31 0.70372 -0.01 0.96987 MirTarget; miRNATAP -0.21 0.01318 NA
30 hsa-miR-15b-5p ADAMTS18 0.25 0.79071 -0.28 0.54902 miRNATAP -0.5 0.0005 NA
31 hsa-miR-107 ADAMTS19 -0.29 0.76966 -0.27 0.71187 miRanda -0.43 0.01932 NA
32 hsa-miR-148a-3p ADAMTS19 -0.32 0.74626 -0.27 0.71187 MirTarget -0.3 0.04059 NA
33 hsa-miR-15b-5p ADAMTS5 0.25 0.79071 -0 0.99654 miRNATAP -0.32 0.00415 NA
34 hsa-miR-221-3p ADAMTS6 -0.26 0.74402 0.13 0.72485 MirTarget -0.18 0.02985 NA
35 hsa-miR-222-3p ADAMTS6 -0.23 0.72665 0.13 0.72485 MirTarget -0.2 0.01296 NA
36 hsa-miR-107 ADAMTSL3 -0.29 0.76966 -0.04 0.93342 MirTarget; PITA; miRanda; miRNATAP -0.29 0.03386 NA
37 hsa-miR-150-5p ADCY1 -0.01 0.99407 -0.14 0.72935 mirMAP -0.2 0.00017 NA
38 hsa-miR-128-3p ADCY2 -0.04 0.95842 -0.16 0.81937 MirTarget -0.77 0.00034 NA
39 hsa-miR-148a-3p ADCY2 -0.32 0.74626 -0.16 0.81937 MirTarget; miRNATAP -0.47 0.00442 NA
40 hsa-miR-107 ADCYAP1 -0.29 0.76966 0.67 0.31207 MirTarget; PITA; miRanda; miRNATAP -0.63 0.00048 NA
41 hsa-miR-150-5p ADCYAP1R1 -0.01 0.99407 0.79 0.27302 mirMAP -0.5 0 NA
42 hsa-miR-148a-5p ADH1B -0.16 0.74468 1.68 0.043 MirTarget -0.38 0.03699 NA
43 hsa-miR-186-5p ADH1B -0.25 0.70131 1.68 0.043 mirMAP -0.6 0.024 NA
44 hsa-miR-200b-5p ADH1B -0.22 0.75029 1.68 0.043 mirMAP -0.45 0.0085 NA
45 hsa-miR-429 ADH1B -0.6 0.12897 1.68 0.043 miRanda -0.55 0.00061 NA
46 hsa-miR-500a-5p ADH1B -0.23 0.51657 1.68 0.043 mirMAP -0.35 0.03941 NA
47 hsa-miR-501-5p ADH1B -0.28 0.51074 1.68 0.043 mirMAP -0.49 0.00262 NA
48 hsa-miR-150-5p ADRA2B -0.01 0.99407 -0.51 0.21804 mirMAP -0.2 0.00073 NA
49 hsa-miR-326 AGBL2 0.31 0.65358 -0.07 0.85033 miRanda -0.23 0.00061 NA
50 hsa-miR-330-5p AGBL2 -0.15 0.78726 -0.07 0.85033 miRanda -0.22 0.02248 NA
51 hsa-miR-22-3p AGBL5 0.05 0.96778 0.09 0.87437 MirTarget; miRNATAP -0.16 1.0E-5 NA
52 hsa-miR-15b-5p AGPAT4 0.25 0.79071 -0.1 0.78351 mirMAP -0.31 2.0E-5 NA
53 hsa-miR-15b-5p AHCYL2 0.25 0.79071 -0 0.99112 miRNATAP -0.11 0.0129 NA
54 hsa-miR-15b-5p AHRR 0.25 0.79071 -0.45 0.15751 mirMAP -0.23 0.01086 NA
55 hsa-miR-25-3p AIM1 0.07 0.95527 0.07 0.88548 miRNAWalker2 validate -0.22 0.01826 NA
56 hsa-miR-335-3p AK1 0.07 0.89349 0.41 0.37901 mirMAP -0.13 0.00047 NA
57 hsa-miR-423-5p AK1 -0.31 0.65889 0.41 0.37901 miRNATAP -0.14 0.03452 NA
58 hsa-miR-128-3p AKR7A2 -0.04 0.95842 0.39 0.44612 MirTarget -0.12 0.00475 NA
59 hsa-miR-107 AKT3 -0.29 0.76966 0.09 0.82989 PITA; miRanda -0.29 0.00414 NA
60 hsa-miR-335-3p ALCAM 0.07 0.89349 -0.65 0.27738 mirMAP -0.19 0.00088 NA
61 hsa-miR-338-3p ALCAM -0.11 0.81804 -0.65 0.27738 miRanda -0.15 0.00345 NA
62 hsa-miR-9-5p ALCAM 0.03 0.96423 -0.65 0.27738 MirTarget; miRNATAP -0.13 0.00075 NA
63 hsa-miR-107 ALDH1A2 -0.29 0.76966 1.22 0.06977 miRanda -0.4 0.03794 NA
64 hsa-miR-27a-3p ALDH9A1 0.31 0.70372 0.05 0.93051 miRNAWalker2 validate -0.14 1.0E-5 NA
65 hsa-miR-100-5p ALG3 0.05 0.9611 0.15 0.80605 miRNAWalker2 validate -0.1 0.00012 NA
66 hsa-miR-150-5p ALS2CR12 -0.01 0.99407 -0.56 0.29016 MirTarget -0.24 0.00019 NA
67 hsa-miR-107 AMFR -0.29 0.76966 0.03 0.95365 miRanda -0.18 1.0E-5 NA
68 hsa-miR-150-5p AMIGO1 -0.01 0.99407 -0.26 0.36185 mirMAP -0.1 0.00023 NA
69 hsa-miR-183-5p AMIGO2 -0.05 0.96949 0.29 0.50394 MirTarget -0.19 0.00026 NA
70 hsa-miR-598-3p AMIGO2 -0.92 0.0471 0.29 0.50394 MirTarget -0.18 0.0005 NA
71 hsa-miR-222-3p AMMECR1 -0.23 0.72665 -0.14 0.77428 miRNATAP -0.11 0.01021 NA
72 hsa-miR-381-3p AMN1 0.27 0.56263 0.13 0.7629 MirTarget -0.15 0.00072 NA
73 hsa-miR-27a-3p AMOTL1 0.31 0.70372 0.66 0.21471 mirMAP -0.15 0.022 NA
74 hsa-miR-27a-3p ANK1 0.31 0.70372 -0.6 0.21009 miRNATAP -0.37 0.00265 NA
75 hsa-miR-15b-5p ANK2 0.25 0.79071 0.08 0.8625 MirTarget; miRNATAP -0.35 0.00362 NA
76 hsa-miR-107 ANKMY2 -0.29 0.76966 0.07 0.8533 miRanda -0.11 0.02675 NA
77 hsa-miR-505-3p ANKMY2 -0.1 0.86868 0.07 0.8533 MirTarget -0.12 0.01595 NA
78 hsa-miR-15b-5p ANKRD13B 0.25 0.79071 0.02 0.94885 miRNATAP -0.25 0.00119 NA
79 hsa-miR-15b-5p ANKRD29 0.25 0.79071 0.38 0.25673 MirTarget -0.26 0.00947 NA
80 hsa-miR-15b-5p ANKRD46 0.25 0.79071 0.12 0.7754 MirTarget -0.17 0.00043 NA
81 hsa-miR-221-3p ANKRD52 -0.26 0.74402 -0.19 0.7473 miRNATAP -0.12 0.00053 NA
82 hsa-miR-222-3p ANKRD52 -0.23 0.72665 -0.19 0.7473 miRNATAP -0.15 2.0E-5 NA
83 hsa-miR-15b-5p ANKS1A 0.25 0.79071 -0.29 0.61184 MirTarget -0.16 0.00069 NA
84 hsa-miR-214-3p ANKS1B 0.03 0.95264 0.31 0.39938 miRNATAP -0.19 0.00081 NA
85 hsa-miR-148a-3p ANKS6 -0.32 0.74626 -0.03 0.94466 mirMAP -0.1 0.00503 NA
86 hsa-let-7b-5p ANP32E 0.4 0.78341 -0.2 0.71077 miRNAWalker2 validate -0.12 0.00025 NA
87 hsa-miR-107 ANTXR1 -0.29 0.76966 0.54 0.42797 miRanda -0.2 0.0116 NA
88 hsa-miR-660-5p ANTXR1 -0.56 0.13827 0.54 0.42797 mirMAP -0.13 0.00946 NA
89 hsa-miR-125a-3p ANXA4 0.12 0.80054 -0.11 0.85578 miRanda -0.13 0.03354 NA
90 hsa-miR-10b-5p AOC3 -0.87 0.50246 0.35 0.40112 mirMAP -0.22 0.00013 NA
91 hsa-miR-361-5p AOC3 -0.28 0.72855 0.35 0.40112 MirTarget; miRanda -0.31 0.02482 NA
92 hsa-miR-107 AP1S2 -0.29 0.76966 0.11 0.78352 PITA; miRanda -0.11 0.03941 NA
93 hsa-miR-107 AP2A1 -0.29 0.76966 -0.05 0.94157 miRanda -0.15 2.0E-5 NA
94 hsa-miR-15b-5p AP2A1 0.25 0.79071 -0.05 0.94157 miRNATAP -0.1 0.00481 NA
95 hsa-miR-107 APBA1 -0.29 0.76966 -0.01 0.97558 miRNATAP -0.22 0.00205 NA
96 hsa-miR-15b-5p APRT 0.25 0.79071 0.41 0.47976 miRNAWalker2 validate -0.12 0.0233 NA
97 hsa-miR-15b-5p AQP11 0.25 0.79071 -0.82 0.00192 MirTarget -0.41 0 NA
98 hsa-miR-27a-3p AQP11 0.31 0.70372 -0.82 0.00192 MirTarget; miRNATAP -0.23 0.00014 NA
99 hsa-miR-485-3p AQP9 0.26 0.65837 0.3 0.58452 MirTarget -0.15 0.03275 NA
100 hsa-miR-885-5p AQP9 -0.12 0.8613 0.3 0.58452 miRNATAP -0.12 0.0401 NA
101 hsa-miR-130b-3p AR -0.25 0.52407 0 0.99407 mirMAP; miRNATAP -0.37 0.00083 NA
102 hsa-miR-130b-5p AR -0.32 0.50818 0 0.99407 mirMAP -0.3 0.01453 NA
103 hsa-miR-212-3p AR -0.12 0.74063 0 0.99407 mirMAP -0.25 0.00866 26553749 Aberrant coexpression of AR and hnRNPH1 and downregulation of miR-212 were detected in prostate tumors and correlate with disease progression in AA men compared with CA men; Ectopic expression of miR-212 mimics downregulated hnRNPH1 transcripts which in turn reduced expression of AR and its splice variant AR-V7 or AR3 in prostate cancer cells
104 hsa-miR-629-3p AR -0.46 0.20921 0 0.99407 mirMAP -0.24 0.01446 NA
105 hsa-miR-22-3p ARC 0.05 0.96778 -0.25 0.59666 mirMAP -0.31 0.00365 NA
106 hsa-miR-128-3p ARHGAP23 -0.04 0.95842 -0.19 0.77018 MirTarget -0.21 0.00446 NA
107 hsa-miR-107 ARHGAP24 -0.29 0.76966 0.11 0.72834 miRanda -0.18 0.01587 NA
108 hsa-miR-98-5p ARHGAP28 -0.05 0.91078 0.32 0.37736 miRNAWalker2 validate; MirTarget -0.22 0.00026 NA
109 hsa-miR-148a-3p ARHGEF17 -0.32 0.74626 -0.3 0.63774 miRNATAP -0.11 0.00677 NA
110 hsa-miR-15b-5p ARL2 0.25 0.79071 0.08 0.89102 MirTarget; miRNATAP -0.16 0.00137 NA
111 hsa-miR-374b-5p ARL4A -0.27 0.47005 0.07 0.83743 mirMAP -0.11 0.01305 NA
112 hsa-miR-106a-5p ARL4C -0.82 0.02545 0.57 0.412 MirTarget; miRNATAP -0.11 0.02502 NA
113 hsa-miR-192-5p ARL4C -0 0.99638 0.57 0.412 miRNAWalker2 validate -0.1 0.04491 NA
114 hsa-miR-30c-5p ARL4C -0.18 0.83318 0.57 0.412 miRNATAP -0.19 0.01644 NA
115 hsa-miR-429 ARL4C -0.6 0.12897 0.57 0.412 miRNATAP -0.11 0.0285 NA
116 hsa-miR-9-5p ARL4C 0.03 0.96423 0.57 0.412 miRNATAP -0.13 0.00024 NA
117 hsa-miR-140-3p ARL6IP1 -0.11 0.90778 -0.02 0.9733 miRNATAP -0.18 1.0E-5 NA
118 hsa-miR-139-5p ARMC2 -0.06 0.91481 -0.03 0.89811 MirTarget -0.11 0.03573 NA
119 hsa-miR-15b-5p ARMC5 0.25 0.79071 -0.11 0.76726 mirMAP; miRNATAP -0.16 4.0E-5 NA
120 hsa-miR-15b-5p ARVCF 0.25 0.79071 -0.63 0.1294 mirMAP -0.17 0.00576 NA
121 hsa-miR-27a-3p ARX 0.31 0.70372 -1.63 0.07012 miRNATAP -0.55 0.0191 NA
122 hsa-miR-214-3p ASF1B 0.03 0.95264 0.09 0.86181 miRNAWalker2 validate -0.11 0.00627 NA
123 hsa-miR-320c ASF1B 0.09 0.78554 0.09 0.86181 miRanda -0.19 0.00079 NA
124 hsa-let-7a-5p ASPM 0.05 0.97156 -0.13 0.76349 miRNAWalker2 validate -0.14 0.03148 NA
125 hsa-miR-101-3p ASPN -0.01 0.982 0.85 0.12992 MirTarget; miRNATAP -0.31 0.03014 NA
126 hsa-miR-129-5p ASPN 0.42 0.45424 0.85 0.12992 miRanda -0.26 0.00225 NA
127 hsa-miR-219a-1-3p ASPN -0.39 0.34551 0.85 0.12992 MirTarget -0.57 1.0E-5 NA
128 hsa-miR-26a-5p ASPN 0.05 0.95522 0.85 0.12992 MirTarget; miRNATAP -0.41 0.0213 NA
129 hsa-miR-26b-5p ASPN 0.16 0.79078 0.85 0.12992 miRNAWalker2 validate; MirTarget; miRNATAP -0.37 0.03842 NA
130 hsa-miR-429 ASPN -0.6 0.12897 0.85 0.12992 miRanda -0.32 0.00256 NA
131 hsa-miR-1266-5p ASTN1 0.19 0.74972 0.61 0.3113 MirTarget -0.37 0.00675 NA
132 hsa-miR-15a-5p ASTN1 -0.29 0.50627 0.61 0.3113 MirTarget -0.45 0.00026 NA
133 hsa-miR-15b-5p ASTN1 0.25 0.79071 0.61 0.3113 MirTarget -0.36 0.04881 NA
134 hsa-miR-16-5p ASTN1 -0.2 0.74283 0.61 0.3113 MirTarget -0.37 0.01417 NA
135 hsa-miR-185-5p ASTN1 -0.65 0.11792 0.61 0.3113 MirTarget -0.47 0.001 NA
136 hsa-miR-200a-3p ASTN1 -0.8 0.14799 0.61 0.3113 MirTarget; miRNATAP -0.3 0.0088 NA
137 hsa-miR-330-5p ASTN1 -0.15 0.78726 0.61 0.3113 MirTarget; miRNATAP -0.51 0.00106 NA
138 hsa-miR-34a-5p ASTN1 -0.69 0.19575 0.61 0.3113 MirTarget -0.28 0.03373 NA
139 hsa-miR-378a-5p ASTN1 -0.03 0.96972 0.61 0.3113 mirMAP -0.39 0.00161 NA
140 hsa-miR-221-3p ASXL3 -0.26 0.74402 0.05 0.92639 miRNAWalker2 validate -0.29 0.02377 NA
141 hsa-miR-26a-5p ATAD2 0.05 0.95522 -0.14 0.79619 MirTarget -0.27 2.0E-5 NA
142 hsa-miR-15b-5p ATF7IP2 0.25 0.79071 -0.19 0.5893 miRNATAP -0.16 0.01442 NA
143 hsa-miR-27a-3p ATOH7 0.31 0.70372 -0.44 0.3265 miRNATAP -0.39 9.0E-5 NA
144 hsa-miR-107 ATP11B -0.29 0.76966 0.04 0.93345 miRanda -0.18 8.0E-5 NA
145 hsa-miR-150-5p ATP1A2 -0.01 0.99407 0.82 0.16452 mirMAP -0.17 0.04551 NA
146 hsa-miR-222-3p ATP7B -0.23 0.72665 -0.1 0.82198 miRNAWalker2 validate -0.23 0.00012 NA
147 hsa-miR-27a-3p ATP7B 0.31 0.70372 -0.1 0.82198 miRNAWalker2 validate -0.17 0.00947 NA
148 hsa-miR-15b-5p ATXN7L1 0.25 0.79071 -0.07 0.85984 miRNATAP -0.14 0.00188 NA
149 hsa-miR-15b-5p ATXN7L2 0.25 0.79071 -0.31 0.35989 MirTarget; miRNATAP -0.14 0.00644 NA
150 hsa-miR-15b-5p ATXN7L3 0.25 0.79071 -0.17 0.74796 MirTarget; miRNATAP -0.12 0.00084 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 214 1518 3.269e-17 1.521e-13
2 POSITIVE REGULATION OF GENE EXPRESSION 235 1733 7.841e-17 1.824e-13
3 NEUROGENESIS 200 1402 1.187e-16 1.842e-13
4 CENTRAL NERVOUS SYSTEM DEVELOPMENT 140 872 6.092e-16 7.087e-13
5 REGULATION OF NEURON DIFFERENTIATION 100 554 6.594e-15 6.137e-12
6 RESPONSE TO ENDOGENOUS STIMULUS 199 1450 8.043e-15 6.238e-12
7 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 232 1805 5.556e-14 3.693e-11
8 REGULATION OF CELL DIFFERENTIATION 199 1492 1.381e-13 8.033e-11
9 TUBE DEVELOPMENT 96 552 2.415e-13 1.248e-10
10 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 216 1672 2.889e-13 1.344e-10
11 CELL DEVELOPMENT 190 1426 5.882e-13 2.488e-10
12 HEAD DEVELOPMENT 113 709 7.555e-13 2.704e-10
13 UROGENITAL SYSTEM DEVELOPMENT 63 299 7.501e-13 2.704e-10
14 REGULATION OF CELL DEVELOPMENT 127 836 9.057e-13 3.01e-10
15 MITOTIC CELL CYCLE 119 766 1.074e-12 3.332e-10
16 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 117 750 1.268e-12 3.688e-10
17 EPITHELIUM DEVELOPMENT 137 945 3.705e-12 9.706e-10
18 CELL DIVISION 82 460 3.755e-12 9.706e-10
19 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 171 1275 5.659e-12 1.386e-09
20 ORGAN MORPHOGENESIS 124 841 1.344e-11 3.128e-09
21 EMBRYO DEVELOPMENT 129 894 2.281e-11 5.055e-09
22 TUBE MORPHOGENESIS 63 323 2.547e-11 5.386e-09
23 BIOLOGICAL ADHESION 143 1032 3.546e-11 7.173e-09
24 CELL CYCLE 172 1316 4.126e-11 8e-09
25 TISSUE MORPHOGENESIS 88 533 4.354e-11 8.104e-09
26 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 140 1008 4.905e-11 8.777e-09
27 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 90 554 6.311e-11 1.049e-08
28 REGULATION OF CELL DEATH 187 1472 6.118e-11 1.049e-08
29 CELLULAR COMPONENT MORPHOGENESIS 128 900 7.3e-11 1.171e-08
30 NEGATIVE REGULATION OF CELL DIFFERENTIATION 96 609 7.98e-11 1.238e-08
31 REGULATION OF CELL CYCLE 133 949 8.366e-11 1.256e-08
32 MORPHOGENESIS OF AN EPITHELIUM 71 400 1.3e-10 1.89e-08
33 CARDIOVASCULAR SYSTEM DEVELOPMENT 115 788 1.465e-10 2.006e-08
34 CIRCULATORY SYSTEM DEVELOPMENT 115 788 1.465e-10 2.006e-08
35 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 152 1142 1.682e-10 2.237e-08
36 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 103 684 2.364e-10 3.055e-08
37 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 215 1784 2.534e-10 3.187e-08
38 FOREBRAIN DEVELOPMENT 65 357 2.644e-10 3.21e-08
39 DEVELOPMENTAL GROWTH 62 333 2.691e-10 3.21e-08
40 NEGATIVE REGULATION OF CELL DEATH 123 872 2.973e-10 3.458e-08
41 GROWTH 71 410 4.035e-10 4.47e-08
42 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 115 801 4.004e-10 4.47e-08
43 REGULATION OF CELL PROLIFERATION 186 1496 4.133e-10 4.472e-08
44 CELL PROLIFERATION 100 672 8.405e-10 8.713e-08
45 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 137 1021 8.427e-10 8.713e-08
46 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 82 513 1.003e-09 9.932e-08
47 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 135 1004 9.846e-10 9.932e-08
48 NEURON DIFFERENTIATION 121 874 1.329e-09 1.289e-07
49 NEURON PROJECTION DEVELOPMENT 85 545 1.678e-09 1.594e-07
50 CELL CYCLE PROCESS 142 1081 1.72e-09 1.6e-07
51 REGULATION OF CELL PROJECTION ORGANIZATION 86 558 2.418e-09 2.206e-07
52 INTRACELLULAR SIGNAL TRANSDUCTION 190 1572 2.597e-09 2.324e-07
53 RESPIRATORY SYSTEM DEVELOPMENT 42 197 3.412e-09 2.995e-07
54 RESPONSE TO GROWTH FACTOR 76 475 3.953e-09 3.406e-07
55 MITOTIC SISTER CHROMATID SEGREGATION 26 91 5.951e-09 5.034e-07
56 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 147 1152 6.231e-09 5.177e-07
57 KIDNEY EPITHELIUM DEVELOPMENT 31 125 9.221e-09 7.398e-07
58 RESPONSE TO HORMONE 120 893 9.178e-09 7.398e-07
59 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 213 1848 1.401e-08 1.105e-06
60 MITOTIC NUCLEAR DIVISION 61 361 1.777e-08 1.378e-06
61 CELL CYCLE PHASE TRANSITION 48 255 1.928e-08 1.471e-06
62 EMBRYONIC MORPHOGENESIS 81 539 2.241e-08 1.682e-06
63 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 125 957 2.4e-08 1.766e-06
64 NEGATIVE REGULATION OF CELL CYCLE 69 433 2.429e-08 1.766e-06
65 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 26 97 2.567e-08 1.837e-06
66 REGULATION OF NEURON PROJECTION DEVELOPMENT 66 408 2.708e-08 1.909e-06
67 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 41 204 3.1e-08 2.153e-06
68 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 34 153 3.542e-08 2.424e-06
69 REGULATION OF TRANSFERASE ACTIVITY 123 946 4.056e-08 2.735e-06
70 GLAND DEVELOPMENT 64 395 4.127e-08 2.743e-06
71 NEGATIVE REGULATION OF PHOSPHORYLATION 67 422 4.475e-08 2.933e-06
72 REGULATION OF ORGANELLE ORGANIZATION 146 1178 4.606e-08 2.976e-06
73 NEGATIVE REGULATION OF MOLECULAR FUNCTION 136 1079 5.062e-08 3.226e-06
74 CELL PROJECTION ORGANIZATION 118 902 5.536e-08 3.481e-06
75 CELL CELL ADHESION 87 608 6.721e-08 4.17e-06
76 REGULATION OF CELLULAR COMPONENT MOVEMENT 104 771 7.655e-08 4.687e-06
77 MULTICELLULAR ORGANISMAL SIGNALING 29 123 9.083e-08 5.489e-06
78 HEART DEVELOPMENT 71 466 9.583e-08 5.717e-06
79 MESONEPHROS DEVELOPMENT 24 90 9.735e-08 5.734e-06
80 REGULATION OF PHOSPHORUS METABOLIC PROCESS 187 1618 9.992e-08 5.812e-06
81 MORPHOGENESIS OF A BRANCHING STRUCTURE 35 167 1.058e-07 6.08e-06
82 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 79 541 1.154e-07 6.395e-06
83 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 79 541 1.154e-07 6.395e-06
84 REGULATION OF MITOTIC CELL CYCLE 71 468 1.137e-07 6.395e-06
85 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 39 199 1.346e-07 7.37e-06
86 REGULATION OF PROTEIN MODIFICATION PROCESS 195 1710 1.376e-07 7.443e-06
87 NEURON DEVELOPMENT 94 687 1.695e-07 9.064e-06
88 POSITIVE REGULATION OF CELL DIFFERENTIATION 108 823 1.766e-07 9.336e-06
89 NEURON PROJECTION MORPHOGENESIS 63 402 1.817e-07 9.498e-06
90 RESPONSE TO OXYGEN CONTAINING COMPOUND 163 1381 1.909e-07 9.87e-06
91 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 124 983 1.944e-07 9.941e-06
92 CYTOSKELETON ORGANIZATION 109 838 2.421e-07 1.211e-05
93 RESPONSE TO ORGANIC CYCLIC COMPOUND 117 917 2.41e-07 1.211e-05
94 REGULATION OF WNT SIGNALING PATHWAY 52 310 2.506e-07 1.241e-05
95 NEGATIVE REGULATION OF GENE EXPRESSION 173 1493 2.68e-07 1.312e-05
96 TUBE FORMATION 29 129 2.708e-07 1.312e-05
97 REGIONALIZATION 52 311 2.781e-07 1.334e-05
98 CELLULAR MACROMOLECULE LOCALIZATION 148 1234 2.829e-07 1.343e-05
99 REGULATION OF SYSTEM PROCESS 74 507 2.956e-07 1.389e-05
100 REGULATION OF TRANSPORT 202 1804 3.054e-07 1.421e-05
101 POSITIVE REGULATION OF CELL DEVELOPMENT 70 472 3.364e-07 1.55e-05
102 PATTERN SPECIFICATION PROCESS 64 418 3.418e-07 1.559e-05
103 REGULATION OF KINASE ACTIVITY 102 776 3.613e-07 1.617e-05
104 PROTEIN PHOSPHORYLATION 119 944 3.588e-07 1.617e-05
105 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 66 437 3.734e-07 1.655e-05
106 REGULATION OF CELLULAR COMPONENT BIOGENESIS 101 767 3.787e-07 1.663e-05
107 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 29 131 3.826e-07 1.664e-05
108 POSITIVE REGULATION OF NEURON DIFFERENTIATION 51 306 3.994e-07 1.721e-05
109 SENSORY ORGAN DEVELOPMENT 72 493 4.17e-07 1.78e-05
110 PROTEIN LOCALIZATION TO MEMBRANE 59 376 4.239e-07 1.793e-05
111 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 85 616 4.637e-07 1.944e-05
112 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 174 1517 4.823e-07 2.004e-05
113 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 187 1656 5.04e-07 2.075e-05
114 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 162 1395 5.817e-07 2.374e-05
115 RESPONSE TO ALCOHOL 57 362 5.906e-07 2.39e-05
116 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 132 1087 6.601e-07 2.648e-05
117 NEGATIVE REGULATION OF CELL DEVELOPMENT 50 303 7.026e-07 2.794e-05
118 TELENCEPHALON DEVELOPMENT 41 228 7.243e-07 2.856e-05
119 REGULATION OF BLOOD CIRCULATION 49 295 7.428e-07 2.905e-05
120 NEGATIVE REGULATION OF CELL PROLIFERATION 87 643 7.907e-07 3.066e-05
121 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 45 262 8.086e-07 3.084e-05
122 POSITIVE REGULATION OF CELL DEATH 83 605 8.042e-07 3.084e-05
123 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 41 229 8.154e-07 3.085e-05
124 RESPONSE TO NITROGEN COMPOUND 109 859 8.221e-07 3.085e-05
125 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 84 616 8.876e-07 3.304e-05
126 RHYTHMIC PROCESS 49 298 1.007e-06 3.717e-05
127 RESPONSE TO STEROID HORMONE 71 497 1.15e-06 4.215e-05
128 SISTER CHROMATID SEGREGATION 34 176 1.184e-06 4.303e-05
129 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 79 573 1.217e-06 4.38e-05
130 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 68 470 1.224e-06 4.38e-05
131 REGULATION OF BINDING 47 283 1.247e-06 4.429e-05
132 CARTILAGE DEVELOPMENT 30 147 1.515e-06 5.339e-05
133 NUCLEAR TRANSCRIBED MRNA CATABOLIC PROCESS NONSENSE MEDIATED DECAY 26 118 1.655e-06 5.79e-05
134 POSITIVE REGULATION OF CELL PROLIFERATION 103 814 1.886e-06 6.549e-05
135 REGULATION OF CELLULAR LOCALIZATION 148 1277 2.078e-06 7.161e-05
136 POSITIVE REGULATION OF CELL COMMUNICATION 172 1532 2.172e-06 7.378e-05
137 REGULATION OF HEART CONTRACTION 39 221 2.168e-06 7.378e-05
138 POSITIVE REGULATION OF MOLECULAR FUNCTION 196 1791 2.243e-06 7.563e-05
139 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 58 387 2.405e-06 8.052e-05
140 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 101 799 2.485e-06 8.26e-05
141 PROTEIN LOCALIZATION 197 1805 2.52e-06 8.317e-05
142 EYE DEVELOPMENT 51 326 2.764e-06 9.057e-05
143 REGULATION OF CYTOPLASMIC TRANSPORT 68 481 2.791e-06 9.08e-05
144 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 35 191 2.949e-06 9.53e-05
145 REGULATION OF CELL CYCLE PROCESS 76 558 3.063e-06 9.828e-05
146 METANEPHRIC MESENCHYME DEVELOPMENT 8 14 3.165e-06 0.0001009
147 SKELETAL SYSTEM DEVELOPMENT 65 455 3.231e-06 0.0001023
148 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 66 465 3.399e-06 0.0001069
149 REGULATION OF EPITHELIAL CELL PROLIFERATION 46 285 3.581e-06 0.0001115
150 NEURAL TUBE FORMATION 22 94 3.593e-06 0.0001115
151 APPENDAGE DEVELOPMENT 32 169 3.772e-06 0.0001155
152 LIMB DEVELOPMENT 32 169 3.772e-06 0.0001155
153 RESPONSE TO ESTRADIOL 29 146 3.972e-06 0.0001208
154 NEGATIVE REGULATION OF TRANSPORT 65 458 4.037e-06 0.000122
155 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 89 689 4.144e-06 0.0001244
156 CONNECTIVE TISSUE DEVELOPMENT 35 194 4.247e-06 0.0001267
157 MUSCLE STRUCTURE DEVELOPMENT 62 432 4.657e-06 0.000138
158 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 55 368 4.73e-06 0.0001393
159 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 154 1360 4.807e-06 0.0001407
160 CARDIAC CONDUCTION 20 82 5.033e-06 0.0001464
161 HEART MORPHOGENESIS 37 212 5.104e-06 0.0001475
162 DIGESTIVE SYSTEM DEVELOPMENT 29 148 5.263e-06 0.0001512
163 REGULATION OF CELL DIVISION 44 272 5.451e-06 0.0001556
164 REGULATION OF MEMBRANE POTENTIAL 52 343 5.629e-06 0.0001597
165 ESTABLISHMENT OF PROTEIN LOCALIZATION TO MEMBRANE 43 264 5.805e-06 0.0001637
166 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 23 104 6.06e-06 0.0001699
167 GLAND MORPHOGENESIS 22 97 6.217e-06 0.0001722
168 PROTEIN TARGETING TO MEMBRANE 30 157 6.194e-06 0.0001722
169 NEGATIVE REGULATION OF CELL CYCLE PROCESS 37 214 6.381e-06 0.0001757
170 RESPONSE TO LIPID 108 888 6.605e-06 0.0001808
171 MESENCHYME DEVELOPMENT 34 190 6.957e-06 0.0001882
172 STEM CELL DIFFERENTIATION 34 190 6.957e-06 0.0001882
173 MUSCLE TISSUE DEVELOPMENT 44 275 7.274e-06 0.0001957
174 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 36 207 7.391e-06 0.0001976
175 EPITHELIAL CELL DIFFERENTIATION 68 495 7.509e-06 0.0001996
176 CELLULAR RESPONSE TO STRESS 172 1565 7.799e-06 0.0002042
177 REGULATION OF INTRACELLULAR TRANSPORT 81 621 7.767e-06 0.0002042
178 NEGATIVE REGULATION OF CELL COMMUNICATION 137 1192 7.811e-06 0.0002042
179 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 36 208 8.263e-06 0.0002148
180 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 47 303 8.445e-06 0.0002183
181 REGULATION OF CELL CYCLE PHASE TRANSITION 49 321 8.578e-06 0.0002205
182 ACTIN FILAMENT BASED PROCESS 63 450 8.802e-06 0.000225
183 VASCULATURE DEVELOPMENT 65 469 8.89e-06 0.000226
184 REGULATION OF PROTEIN BINDING 31 168 9.19e-06 0.0002319
185 RESPONSE TO INORGANIC SUBSTANCE 66 479 9.222e-06 0.0002319
186 POSITIVE REGULATION OF CELL CYCLE 50 332 1.018e-05 0.0002547
187 NEPHRON EPITHELIUM DEVELOPMENT 21 93 1.079e-05 0.0002684
188 NEPHRON DEVELOPMENT 24 115 1.101e-05 0.0002726
189 SOMATIC STEM CELL POPULATION MAINTENANCE 17 66 1.167e-05 0.0002873
190 REGULATION OF TRANSMEMBRANE TRANSPORT 60 426 1.187e-05 0.0002908
191 NEGATIVE REGULATION OF LOCOMOTION 42 263 1.22e-05 0.0002971
192 REPRODUCTIVE SYSTEM DEVELOPMENT 58 408 1.249e-05 0.0003027
193 REGULATION OF CELL MORPHOGENESIS 73 552 1.349e-05 0.0003252
194 MAINTENANCE OF CELL NUMBER 26 132 1.439e-05 0.0003452
195 NEURON PROJECTION GUIDANCE 35 205 1.487e-05 0.0003549
196 CELL PART MORPHOGENESIS 81 633 1.576e-05 0.0003741
197 LOCOMOTION 128 1114 1.59e-05 0.0003755
198 SEX DIFFERENTIATION 42 266 1.616e-05 0.0003798
199 CELL MOTILITY 101 835 1.653e-05 0.0003845
200 LOCALIZATION OF CELL 101 835 1.653e-05 0.0003845
201 IN UTERO EMBRYONIC DEVELOPMENT 47 311 1.694e-05 0.0003921
202 NEURAL TUBE DEVELOPMENT 28 149 1.723e-05 0.0003969
203 RESPONSE TO KETONE 32 182 1.853e-05 0.0004247
204 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 26 134 1.9e-05 0.000427
205 CELL CYCLE G1 S PHASE TRANSITION 23 111 1.883e-05 0.000427
206 G1 S TRANSITION OF MITOTIC CELL CYCLE 23 111 1.883e-05 0.000427
207 KIDNEY MORPHOGENESIS 19 82 1.897e-05 0.000427
208 RESPONSE TO ABIOTIC STIMULUS 119 1024 1.913e-05 0.0004279
209 EMBRYONIC ORGAN DEVELOPMENT 57 406 2.137e-05 0.0004758
210 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 11 32 2.186e-05 0.0004843
211 POSITIVE REGULATION OF CATALYTIC ACTIVITY 165 1518 2.233e-05 0.000491
212 PHOSPHORYLATION 138 1228 2.237e-05 0.000491
213 REGULATION OF CYTOSKELETON ORGANIZATION 67 502 2.249e-05 0.0004913
214 MICROTUBULE BASED PROCESS 69 522 2.341e-05 0.0005091
215 RESPONSE TO ESTROGEN 36 218 2.39e-05 0.0005172
216 CELLULAR RESPONSE TO HORMONE STIMULUS 72 552 2.455e-05 0.0005288
217 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 28 152 2.523e-05 0.000541
218 REGULATION OF HOMEOSTATIC PROCESS 61 447 2.663e-05 0.0005684
219 CELLULAR RESPONSE TO NITROGEN COMPOUND 67 505 2.721e-05 0.0005781
220 SPINAL CORD DEVELOPMENT 22 106 2.762e-05 0.0005842
221 HINDBRAIN DEVELOPMENT 26 137 2.843e-05 0.0005959
222 ORGANELLE FISSION 66 496 2.84e-05 0.0005959
223 PALLIUM DEVELOPMENT 28 153 2.857e-05 0.0005961
224 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 206 1977 2.997e-05 0.0006226
225 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 31 178 3.011e-05 0.0006226
226 NEGATIVE REGULATION OF CALCIUM ION TRANSPORT 14 51 3.144e-05 0.0006474
227 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 49 337 3.192e-05 0.0006543
228 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 27 146 3.252e-05 0.0006637
229 LUNG MORPHOGENESIS 13 45 3.317e-05 0.0006702
230 RENAL TUBULE DEVELOPMENT 18 78 3.307e-05 0.0006702
231 MODULATION OF SYNAPTIC TRANSMISSION 45 301 3.327e-05 0.0006702
232 KIDNEY MESENCHYME DEVELOPMENT 8 18 3.447e-05 0.0006913
233 RESPONSE TO INCREASED OXYGEN LEVELS 9 23 3.778e-05 0.0007513
234 RESPONSE TO HYPEROXIA 9 23 3.778e-05 0.0007513
235 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 37 232 4.042e-05 0.0008004
236 LUNG EPITHELIUM DEVELOPMENT 11 34 4.175e-05 0.0008232
237 NEGATIVE REGULATION OF KINASE ACTIVITY 39 250 4.207e-05 0.0008259
238 NEURAL NUCLEUS DEVELOPMENT 16 66 4.712e-05 0.0009212
239 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 50 352 4.938e-05 0.0009614
240 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 14 53 5.026e-05 0.0009703
241 NEGATIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 10 29 5.024e-05 0.0009703
242 EMBRYONIC ORGAN MORPHOGENESIS 42 279 5.1e-05 0.0009806
243 POSITIVE REGULATION OF RESPONSE TO STIMULUS 200 1929 5.325e-05 0.00102
244 MESENCHYMAL CELL DIFFERENTIATION 25 134 5.398e-05 0.001029
245 CELLULAR RESPONSE TO ACID CHEMICAL 30 175 5.445e-05 0.001034
246 METANEPHROS DEVELOPMENT 18 81 5.644e-05 0.001068
247 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 23 119 5.994e-05 0.001129
248 CELLULAR RESPONSE TO OXYGEN LEVELS 26 143 6.088e-05 0.001142
249 NUCLEAR CHROMOSOME SEGREGATION 36 228 6.319e-05 0.001181
250 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 21 104 6.374e-05 0.001186
251 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 89 740 6.418e-05 0.00119
252 SECOND MESSENGER MEDIATED SIGNALING 28 160 6.551e-05 0.00121
253 REGULATION OF PROTEIN COMPLEX ASSEMBLY 52 375 6.701e-05 0.001232
254 RESPONSE TO ACID CHEMICAL 46 319 6.739e-05 0.001234
255 HEPATICOBILIARY SYSTEM DEVELOPMENT 24 128 6.95e-05 0.001268
256 POSITIVE REGULATION OF CELL CYCLE PROCESS 38 247 7.115e-05 0.001293
257 SINGLE ORGANISM CELLULAR LOCALIZATION 104 898 7.345e-05 0.00133
258 CEREBRAL CORTEX DEVELOPMENT 21 105 7.376e-05 0.00133
259 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 11 36 7.554e-05 0.001352
260 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 11 36 7.554e-05 0.001352
261 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 75 602 7.803e-05 0.001391
262 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 23 121 7.843e-05 0.001393
263 ESTABLISHMENT OF LOCALIZATION IN CELL 176 1676 7.968e-05 0.00141
264 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 20 98 8.077e-05 0.001424
265 BLASTOCYST DEVELOPMENT 15 62 8.268e-05 0.001452
266 MICROTUBULE BASED MOVEMENT 33 205 8.56e-05 0.001496
267 AXONAL FASCICULATION 8 20 8.582e-05 0.001496
268 TRANSLATIONAL INITIATION 26 146 8.725e-05 0.001515
269 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 23 122 8.946e-05 0.001547
270 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 36 232 9.11e-05 0.00157
271 CHROMOSOME ORGANIZATION 114 1009 9.392e-05 0.001601
272 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 20 99 9.372e-05 0.001601
273 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 20 99 9.372e-05 0.001601
274 NEGATIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 21 107 9.81e-05 0.00166
275 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 26 147 9.807e-05 0.00166
276 MITOTIC CELL CYCLE CHECKPOINT 25 139 0.0001003 0.001691
277 REGULATION OF TRANSPORTER ACTIVITY 32 198 0.0001007 0.001692
278 REGULATION OF METAL ION TRANSPORT 46 325 0.0001058 0.001771
279 MITOTIC DNA INTEGRITY CHECKPOINT 20 100 0.0001085 0.001809
280 REGULATION OF CHROMOSOME SEGREGATION 18 85 0.0001098 0.001818
281 POSITIVE REGULATION OF CELL CYCLE ARREST 18 85 0.0001098 0.001818
282 REGULATION OF PROTEIN LOCALIZATION 108 950 0.0001124 0.001855
283 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 22 116 0.0001151 0.001879
284 POSITIVE REGULATION OF CELL DIVISION 24 132 0.000115 0.001879
285 RESPONSE TO DRUG 57 431 0.0001149 0.001879
286 SOMITE DEVELOPMENT 17 78 0.0001162 0.00189
287 POSITIVE REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS 15 64 0.0001218 0.001974
288 REGULATION OF CALCIUM ION TRANSPORT 33 209 0.0001252 0.002021
289 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 158 1492 0.0001255 0.002021
290 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 36 236 0.0001297 0.002074
291 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 10 32 0.0001296 0.002074
292 POSITIVE REGULATION OF KINASE ACTIVITY 62 482 0.0001307 0.002076
293 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 86 724 0.0001304 0.002076
294 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 125 1135 0.0001318 0.002087
295 REGULATION OF ION TRANSPORT 73 592 0.0001334 0.002104
296 ACTION POTENTIAL 19 94 0.0001379 0.002168
297 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 96 829 0.0001386 0.002171
298 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 102 0.0001443 0.002253
299 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 54 406 0.0001483 0.002306
300 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 23 126 0.0001487 0.002306
301 RESPONSE TO OXYGEN LEVELS 44 311 0.0001493 0.002308
302 UV PROTECTION 6 12 0.0001562 0.002407
303 ANTERIOR POSTERIOR PATTERN SPECIFICATION 31 194 0.0001586 0.002427
304 CELL CYCLE CHECKPOINT 31 194 0.0001586 0.002427
305 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 9 27 0.0001616 0.002458
306 AXIS ELONGATION 9 27 0.0001616 0.002458
307 REGULATION OF MUSCLE TISSUE DEVELOPMENT 20 103 0.0001658 0.002513
308 CELLULAR RESPONSE TO LIPID 59 457 0.0001704 0.002575
309 NEURON RECOGNITION 10 33 0.0001728 0.002593
310 EMBRYONIC EYE MORPHOGENESIS 10 33 0.0001728 0.002593
311 REGULATION OF MUSCLE SYSTEM PROCESS 31 195 0.0001744 0.002609
312 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 48 351 0.0001755 0.002617
313 REGULATION OF CARDIAC MUSCLE CONTRACTION 15 66 0.0001761 0.002617
314 EXTRACELLULAR STRUCTURE ORGANIZATION 43 304 0.0001773 0.002628
315 MEMBRANE ORGANIZATION 102 899 0.0001866 0.002757
316 RESPONSE TO METAL ION 46 333 0.0001877 0.002764
317 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 8 22 0.0001885 0.002767
318 SYNAPSE ORGANIZATION 25 145 0.0002005 0.002934
319 EPITHELIAL CELL PROLIFERATION 18 89 0.0002031 0.002963
320 REGULATION OF CHROMOSOME ORGANIZATION 40 278 0.0002044 0.002971
321 NEGATIVE REGULATION OF CELL DIVISION 14 60 0.0002137 0.003097
322 CELL CELL SIGNALING 89 767 0.0002245 0.003244
323 POSITIVE REGULATION OF TRANSPORT 105 936 0.0002306 0.003322
324 PEPTIDYL AMINO ACID MODIFICATION 96 841 0.0002315 0.003323
325 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 41 289 0.0002325 0.003323
326 MULTI ORGANISM METABOLIC PROCESS 24 138 0.0002328 0.003323
327 RESPONSE TO PEPTIDE 53 404 0.0002402 0.003418
328 RESPONSE TO VITAMIN 19 98 0.000244 0.003462
329 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 22 122 0.0002457 0.003475
330 REGULATION OF EMBRYONIC DEVELOPMENT 21 114 0.0002486 0.003505
331 CHROMOSOME SEGREGATION 39 272 0.0002621 0.003685
332 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 114 1036 0.0002682 0.003734
333 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 8 23 0.0002689 0.003734
334 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 114 1036 0.0002682 0.003734
335 NEUROTROPHIN SIGNALING PATHWAY 8 23 0.0002689 0.003734
336 PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 22 123 0.000277 0.003836
337 PEPTIDYL SERINE MODIFICATION 25 148 0.0002781 0.003839
338 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 33 218 0.00028 0.003843
339 RNA CATABOLIC PROCESS 34 227 0.0002795 0.003843
340 ORGANONITROGEN COMPOUND METABOLIC PROCESS 183 1796 0.0002817 0.003844
341 CELLULAR RESPONSE TO ALCOHOL 21 115 0.0002816 0.003844
342 CELL DEATH IN RESPONSE TO OXIDATIVE STRESS 7 18 0.0002969 0.004028
343 MITOTIC SPINDLE ORGANIZATION 15 69 0.0002964 0.004028
344 REGULATION OF ION HOMEOSTASIS 31 201 0.0003027 0.004082
345 SKELETAL SYSTEM MORPHOGENESIS 31 201 0.0003027 0.004082
346 REGULATION OF CELL ADHESION 75 629 0.0003067 0.004124
347 REGULATION OF KIDNEY DEVELOPMENT 13 55 0.0003108 0.004168
348 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 18 92 0.0003129 0.004184
349 REGULATION OF ACTIN FILAMENT BASED PROCESS 43 312 0.0003144 0.004192
350 RESPONSE TO FIBROBLAST GROWTH FACTOR 21 116 0.0003184 0.004233
351 METENCEPHALON DEVELOPMENT 19 100 0.0003199 0.004241
352 REGULATION OF CELL CYCLE ARREST 20 108 0.0003214 0.004249
353 CELLULAR RESPONSE TO OXIDATIVE STRESS 29 184 0.0003224 0.00425
354 ACTOMYOSIN STRUCTURE ORGANIZATION 16 77 0.0003262 0.004287
355 METAPHASE PLATE CONGRESSION 11 42 0.0003446 0.004517
356 RESPONSE TO OXIDATIVE STRESS 47 352 0.0003538 0.004624
357 REGULATION OF RECEPTOR ACTIVITY 21 117 0.0003594 0.004671
358 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 21 117 0.0003594 0.004671
359 RESPONSE TO HYDROGEN PEROXIDE 20 109 0.0003646 0.004725
360 REGULATION OF GROWTH 75 633 0.0003705 0.004789
361 REGULATION OF AXONOGENESIS 27 168 0.0003715 0.004789
362 CHEMICAL HOMEOSTASIS 98 874 0.0003754 0.004814
363 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 13 56 0.0003756 0.004814
364 EPITHELIAL CELL DEVELOPMENT 29 186 0.0003878 0.004957
365 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 9 30 0.0003964 0.005053
366 RAS PROTEIN SIGNAL TRANSDUCTION 24 143 0.0004023 0.005114
367 INTRACELLULAR PROTEIN TRANSPORT 89 781 0.0004089 0.005185
368 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 11 43 0.00043 0.005437
369 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 7 19 0.0004379 0.005506
370 NEGATIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 7 19 0.0004379 0.005506
371 COGNITION 36 251 0.0004403 0.005515
372 REGULATION OF STRIATED MUSCLE CONTRACTION 16 79 0.0004421 0.005515
373 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 14 0.0004414 0.005515
374 ESTABLISHMENT OF PROTEIN LOCALIZATION 148 1423 0.000461 0.005735
375 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 30 197 0.0004674 0.005799
376 REGULATION OF MUSCLE ORGAN DEVELOPMENT 19 103 0.000472 0.005841
377 REGULATION OF MICROTUBULE BASED PROCESS 35 243 0.0004848 0.005921
378 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 10 37 0.0004843 0.005921
379 CARDIAC MUSCLE CELL ACTION POTENTIAL 10 37 0.0004843 0.005921
380 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 10 37 0.0004843 0.005921
381 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 26 162 0.0004829 0.005921
382 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 32 216 0.0005056 0.006158
383 MICROTUBULE CYTOSKELETON ORGANIZATION 46 348 0.0005077 0.006168
384 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 8 25 0.0005134 0.006189
385 DNA STRAND ELONGATION INVOLVED IN DNA REPLICATION 8 25 0.0005134 0.006189
386 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 8 25 0.0005134 0.006189
387 REGULATION OF MICROTUBULE POLYMERIZATION 9 31 0.0005192 0.006243
388 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 19 104 0.000535 0.006416
389 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 61 498 0.0005458 0.006529
390 DNA INTEGRITY CHECKPOINT 24 146 0.0005492 0.006552
391 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 29 190 0.0005545 0.006598
392 CELLULAR RESPONSE TO KETONE 15 73 0.0005619 0.00667
393 CELL CYCLE G2 M PHASE TRANSITION 23 138 0.0005816 0.006886
394 STRIATED MUSCLE CELL DIFFERENTIATION 27 173 0.0005956 0.007034
395 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 31 209 0.0006009 0.007078
396 RESPONSE TO REACTIVE OXYGEN SPECIES 29 191 0.0006049 0.007108
397 REGULATION OF MUSCLE CONTRACTION 24 147 0.0006076 0.007121
398 REGULATION OF CELLULAR PROTEIN LOCALIZATION 66 552 0.0006378 0.007457
399 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 13 59 0.0006424 0.007492
400 CELLULAR RESPONSE TO IONIZING RADIATION 12 52 0.0006613 0.007693
401 NEGATIVE REGULATION OF BINDING 22 131 0.0006817 0.00791
402 GLIOGENESIS 27 175 0.000714 0.008255
403 CARDIAC MUSCLE TISSUE DEVELOPMENT 23 140 0.000715 0.008255
404 REGULATION OF HYDROLASE ACTIVITY 138 1327 0.0007194 0.008286
405 SENSORY ORGAN MORPHOGENESIS 34 239 0.0007246 0.008325
406 MUSCLE ORGAN DEVELOPMENT 38 277 0.0007443 0.00853
407 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 15 75 0.0007576 0.008661
408 RESPONSE TO CORTICOSTEROID 27 176 0.0007806 0.008902
409 REGULATION OF POTASSIUM ION TRANSPORT 16 83 0.0007829 0.008907
410 DORSAL VENTRAL PATTERN FORMATION 17 91 0.0007912 0.008941
411 MESONEPHRIC TUBULE MORPHOGENESIS 12 53 0.0007936 0.008941
412 CELLULAR RESPONSE TO AMINO ACID STIMULUS 12 53 0.0007936 0.008941
413 REPRODUCTION 135 1297 0.0007922 0.008941
414 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 11 46 0.0007988 0.008978
415 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 24 150 0.0008166 0.009142
416 ORGANONITROGEN COMPOUND BIOSYNTHETIC PROCESS 110 1024 0.0008174 0.009142
417 ORGAN GROWTH 14 68 0.0008314 0.009278
418 REGULATION OF SYNAPTIC VESICLE EXOCYTOSIS 7 21 0.0008766 0.009758
419 REGULATION OF DEVELOPMENTAL GROWTH 39 289 0.0008792 0.009763
420 NEGATIVE REGULATION OF CELL ADHESION 32 223 0.0008812 0.009763
421 CYTOKINESIS 16 84 0.0008967 0.009896
422 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 13 61 0.0008975 0.009896
423 REGULATION OF ORGAN MORPHOGENESIS 34 242 0.0009051 0.009956
424 REGULATION OF RYANODINE SENSITIVE CALCIUM RELEASE CHANNEL ACTIVITY 8 27 0.0009125 0.009991
425 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 8 27 0.0009125 0.009991
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE ACTIVITY 118 842 1.034e-09 9.603e-07
2 PROTEIN KINASE ACTIVITY 94 640 5.351e-09 1.799e-06
3 RIBONUCLEOTIDE BINDING 216 1860 5.811e-09 1.799e-06
4 ENZYME BINDING 203 1737 1.088e-08 2.021e-06
5 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 130 992 1.014e-08 2.021e-06
6 MACROMOLECULAR COMPLEX BINDING 170 1399 1.352e-08 2.093e-06
7 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 150 1199 1.613e-08 2.141e-06
8 CALCIUM ION BINDING 98 697 2.4e-08 2.787e-06
9 CYTOSKELETAL PROTEIN BINDING 110 819 4.013e-08 3.728e-06
10 ADENYL NUCLEOTIDE BINDING 179 1514 3.973e-08 3.728e-06
11 SEQUENCE SPECIFIC DNA BINDING 130 1037 1.384e-07 1.169e-05
12 MICROTUBULE MOTOR ACTIVITY 21 77 4.028e-07 3.119e-05
13 PROTEIN COMPLEX BINDING 117 935 6.586e-07 4.706e-05
14 DOUBLE STRANDED DNA BINDING 99 764 1.036e-06 6.876e-05
15 ION CHANNEL BINDING 25 111 1.703e-06 0.0001055
16 REGULATORY REGION NUCLEIC ACID BINDING 103 818 2.356e-06 0.0001368
17 KINASE BINDING 81 606 3.054e-06 0.000158
18 PROTEIN SERINE THREONINE KINASE ACTIVITY 64 445 3.061e-06 0.000158
19 MOTOR ACTIVITY 26 131 1.249e-05 0.0006109
20 IDENTICAL PROTEIN BINDING 137 1209 1.593e-05 0.0007401
21 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 97 820 5.78e-05 0.002557
22 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 78 629 6.605e-05 0.002557
23 MOLECULAR FUNCTION REGULATOR 147 1353 6.543e-05 0.002557
24 TUBULIN BINDING 41 273 6.576e-05 0.002557
25 GLYCOSAMINOGLYCAN BINDING 33 205 8.56e-05 0.003181
26 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 35 226 0.0001179 0.004212
27 INSULIN RECEPTOR BINDING 10 32 0.0001296 0.004368
28 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 46 328 0.0001317 0.004368
29 PROTEIN DIMERIZATION ACTIVITY 126 1149 0.0001488 0.004719
30 RECEPTOR BINDING 156 1476 0.0001524 0.004719
31 KINASE INHIBITOR ACTIVITY 18 89 0.0002031 0.006087
32 CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY 9 28 0.0002214 0.006428
33 CHANNEL REGULATOR ACTIVITY 23 131 0.0002698 0.007595
34 KINASE REGULATOR ACTIVITY 29 186 0.0003878 0.009886
35 PROTEIN C TERMINUS BINDING 29 186 0.0003878 0.009886
36 RNA POLYMERASE II TRANSCRIPTION COACTIVATOR ACTIVITY 10 36 0.0003804 0.009886
37 PROTEIN DOMAIN SPECIFIC BINDING 74 624 0.0003937 0.009886
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PROJECTION 141 942 1.477e-13 8.628e-11
2 NEURON PART 169 1265 1.053e-11 2.162e-09
3 CELL PROJECTION 221 1786 1.111e-11 2.162e-09
4 CELL JUNCTION 148 1151 3.293e-09 4.808e-07
5 CYTOSKELETON 226 1967 6.135e-09 7.166e-07
6 SOMATODENDRITIC COMPARTMENT 93 650 2.37e-08 2.307e-06
7 EXTRACELLULAR MATRIX 64 426 6.749e-07 4.056e-05
8 MICROTUBULE CYTOSKELETON 130 1068 7.089e-07 4.056e-05
9 PROTEINACEOUS EXTRACELLULAR MATRIX 56 356 7.64e-07 4.056e-05
10 CYTOSOLIC RIBOSOME 26 113 6.874e-07 4.056e-05
11 DENDRITE 67 451 5.623e-07 4.056e-05
12 SYNAPSE 98 754 1.026e-06 4.608e-05
13 SPINDLE 48 289 9.624e-07 4.608e-05
14 MICROTUBULE ASSOCIATED COMPLEX 30 145 1.12e-06 4.673e-05
15 MITOTIC SPINDLE 16 55 3.797e-06 0.0001478
16 CYTOSKELETAL PART 161 1436 5.11e-06 0.0001865
17 CELL PROJECTION PART 113 946 9.235e-06 0.0003173
18 MICROTUBULE 58 405 9.984e-06 0.0003239
19 KINESIN COMPLEX 15 55 1.8e-05 0.0005026
20 CYTOSOLIC LARGE RIBOSOMAL SUBUNIT 16 61 1.636e-05 0.0005026
21 ANCHORING JUNCTION 66 489 1.807e-05 0.0005026
22 CATION CHANNEL COMPLEX 30 167 2.183e-05 0.0005796
23 POSTSYNAPSE 53 378 4.248e-05 0.001079
24 SITE OF POLARIZED GROWTH 27 149 4.712e-05 0.001146
25 SYNAPSE PART 76 610 6.998e-05 0.001635
26 POTASSIUM CHANNEL COMPLEX 19 90 7.471e-05 0.001678
27 CELL BODY 64 494 8.321e-05 0.0018
28 CELL SUBSTRATE JUNCTION 54 398 8.805e-05 0.001837
29 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 10 31 9.596e-05 0.001932
30 MIDBODY 24 132 0.000115 0.002238
31 EXTRACELLULAR MATRIX COMPONENT 23 125 0.0001313 0.002473
32 SPINDLE MIDZONE 9 27 0.0001616 0.0029
33 CELL LEADING EDGE 48 350 0.0001639 0.0029
34 AXON 55 418 0.0001714 0.002906
35 PLASMA MEMBRANE REGION 105 929 0.0001742 0.002906
36 CYTOSOLIC PART 34 223 0.0001987 0.003223
37 EXCITATORY SYNAPSE 31 197 0.0002104 0.00332
38 CELL CELL JUNCTION 51 383 0.0002172 0.003338
39 RIBOSOMAL SUBUNIT 27 163 0.0002254 0.003375
40 MEMBRANE REGION 123 1134 0.0002785 0.004066
41 CHROMOSOME 99 880 0.0003126 0.004452
42 SPINDLE POLE 22 126 0.0003931 0.005443
43 PLASMA MEMBRANE RAFT 17 86 0.0004007 0.005443
44 CONDENSED CHROMOSOME CENTROMERIC REGION 19 102 0.0004155 0.005515
45 CYTOPLASMIC SIDE OF MEMBRANE 27 170 0.0004502 0.005842
46 LARGE RIBOSOMAL SUBUNIT 18 95 0.000471 0.005979
47 LAMELLIPODIUM 27 172 0.0005431 0.006608
48 SPINDLE MICROTUBULE 13 58 0.0005398 0.006608
49 PRONUCLEUS 6 15 0.0006861 0.008177
50 CONDENSED CHROMOSOME 29 195 0.0008491 0.009918

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_cycle_hsa04110 29 124 1.096e-07 5.7e-06
2 PI3K_Akt_signaling_pathway_hsa04151 56 352 5.271e-07 1.37e-05
3 Cellular_senescence_hsa04218 32 160 1.097e-06 1.902e-05
4 p53_signaling_pathway_hsa04115 18 68 4.272e-06 5.554e-05
5 Oocyte_meiosis_hsa04114 25 124 1.373e-05 0.0001247
6 FoxO_signaling_pathway_hsa04068 26 132 1.439e-05 0.0001247
7 Hippo_signaling_pathway_hsa04390 28 154 3.23e-05 0.0002399
8 Rap1_signaling_pathway_hsa04015 32 206 0.0002137 0.001389
9 Ras_signaling_pathway_hsa04014 34 232 0.0004209 0.002432
10 Apelin_signaling_pathway_hsa04371 23 137 0.0005235 0.002722
11 TGF_beta_signaling_pathway_hsa04350 16 84 0.0008967 0.004239
12 Tight_junction_hsa04530 26 170 0.001012 0.004386
13 MAPK_signaling_pathway_hsa04010 39 295 0.001298 0.005193
14 AMPK_signaling_pathway_hsa04152 20 121 0.001429 0.00528
15 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 22 139 0.001523 0.00528
16 Hedgehog_signaling_pathway_hsa04340 10 47 0.003463 0.01126
17 Wnt_signaling_pathway_hsa04310 21 146 0.006103 0.01867
18 Focal_adhesion_hsa04510 26 199 0.00888 0.02565
19 Phospholipase_D_signaling_pathway_hsa04072 20 146 0.01234 0.03339
20 ECM_receptor_interaction_hsa04512 13 82 0.01284 0.03339
21 ErbB_signaling_pathway_hsa04012 13 85 0.01706 0.04224
22 cGMP_PKG_signaling_pathway_hsa04022 21 163 0.02006 0.04742
23 Cell_adhesion_molecules_.CAMs._hsa04514 19 145 0.02224 0.05028
24 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.02485 0.05384
25 Adherens_junction_hsa04520 11 72 0.02707 0.05631
26 cAMP_signaling_pathway_hsa04024 23 198 0.04477 0.08954
27 Apoptosis_hsa04210 17 138 0.04876 0.09391
28 Mitophagy_animal_hsa04137 9 65 0.07262 0.1349
29 mTOR_signaling_pathway_hsa04150 17 151 0.09494 0.1666
30 VEGF_signaling_pathway_hsa04370 8 59 0.09611 0.1666
31 Regulation_of_actin_cytoskeleton_hsa04810 22 208 0.1077 0.1807
32 Calcium_signaling_pathway_hsa04020 19 182 0.1394 0.2265
33 Sphingolipid_signaling_pathway_hsa04071 13 118 0.1479 0.2331
34 Peroxisome_hsa04146 9 83 0.2168 0.3304
35 Autophagy_animal_hsa04140 13 128 0.2224 0.3304
36 Apoptosis_multiple_species_hsa04215 4 33 0.2684 0.3782
37 Gap_junction_hsa04540 9 88 0.2692 0.3782
38 HIF_1_signaling_pathway_hsa04066 10 100 0.2764 0.3782
39 Jak_STAT_signaling_pathway_hsa04630 15 162 0.314 0.4187
40 ABC_transporters_hsa02010 4 45 0.4892 0.636
41 Necroptosis_hsa04217 13 164 0.5538 0.7023
42 Ferroptosis_hsa04216 3 40 0.6299 0.7782
43 NF_kappa_B_signaling_pathway_hsa04064 7 95 0.6435 0.7782
44 Phosphatidylinositol_signaling_system_hsa04070 7 99 0.6861 0.8108
45 Notch_signaling_pathway_hsa04330 3 48 0.7492 0.8492
46 Cytokine_cytokine_receptor_interaction_hsa04060 19 270 0.7512 0.8492
47 Lysosome_hsa04142 8 123 0.7758 0.8583
48 Neuroactive_ligand_receptor_interaction_hsa04080 19 278 0.7932 0.8593
49 TNF_signaling_pathway_hsa04668 6 108 0.8711 0.9211
50 Endocytosis_hsa04144 15 244 0.8856 0.9211
51 Phagosome_hsa04145 5 152 0.9947 1

lncRNA-mediated sponge

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Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

NR2F1-AS1

 hsa-miR-101-3p;hsa-miR-141-5p;hsa-miR-146a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-200a-5p;hsa-miR-224-5p;hsa-miR-616-5p;hsa-miR-625-5p;hsa-miR-629-3p;hsa-miR-942-5p 11 IGFBP5 Sponge network 0.222 0.51468 0.3 0.70154 0.362
2

NR2F1-AS1

 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-186-5p;hsa-miR-27a-5p;hsa-miR-616-5p;hsa-miR-744-3p;hsa-miR-93-5p;hsa-miR-940;hsa-miR-942-5p 10 HLF Sponge network 0.222 0.51468 -0.407 0.26253 0.283

Quest ID: 0f56e205a324c8226fd9483dae32e6db