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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-429 ABCA1 -2.17 0 1.48 0 miRNATAP -0.35 0 NA
2 hsa-miR-429 ABCB4 -2.17 0 1.58 0 miRanda -0.35 0 NA
3 hsa-miR-429 ABCB5 -2.17 0 0.86 0.01229 miRanda -0.21 0.03446 NA
4 hsa-miR-429 ABCD2 -2.17 0 0.83 3.0E-5 miRanda -0.25 1.0E-5 NA
5 hsa-miR-429 ABL2 -2.17 0 0.74 0 MirTarget -0.22 0 NA
6 hsa-miR-429 ACAD11 -2.17 0 1.27 0 miRanda -0.18 0.00045 NA
7 hsa-miR-429 ACE -2.17 0 1.62 0 miRanda -0.39 0 NA
8 hsa-miR-429 ACTN1 -2.17 0 0.73 0 miRanda -0.23 0 NA
9 hsa-miR-429 ACVRL1 -2.17 0 0.72 0 miRNATAP -0.17 0 NA
10 hsa-miR-429 ADAM11 -2.17 0 1.69 0 miRNATAP -0.38 0 NA
11 hsa-miR-429 ADAM12 -2.17 0 1.67 0 miRanda; miRNATAP -0.58 0 NA
12 hsa-miR-429 ADAM19 -2.17 0 1.49 0 miRanda; miRNATAP -0.44 0 NA
13 hsa-miR-429 ADAM28 -2.17 0 1.21 0 miRanda -0.19 3.0E-5 NA
14 hsa-miR-429 ADAM9 -2.17 0 0.34 0.00065 miRanda -0.11 6.0E-5 NA
15 hsa-miR-429 ADAMDEC1 -2.17 0 5.01 0 miRanda -1.04 0 NA
16 hsa-miR-429 ADAMTS10 -2.17 0 1.97 0 miRNATAP -0.37 0 NA
17 hsa-miR-429 ADAMTS18 -2.17 0 1.09 0 miRanda; miRNATAP -0.31 0 NA
18 hsa-miR-429 ADAMTS2 -2.17 0 1.6 0 miRNATAP -0.45 0 NA
19 hsa-miR-429 ADAMTS4 -2.17 0 2.68 0 miRanda -0.63 0 NA
20 hsa-miR-429 ADAP2 -2.17 0 1.91 0 miRanda -0.38 0 NA
21 hsa-miR-429 ADCY2 -2.17 0 1.55 0 MirTarget; PITA; miRanda; miRNATAP -0.25 0.01244 NA
22 hsa-miR-429 ADCY7 -2.17 0 1.81 0 miRanda -0.34 0 NA
23 hsa-miR-429 ADORA3 -2.17 0 3.22 0 miRNATAP -0.59 0 NA
24 hsa-miR-429 AFF2 -2.17 0 0.98 0 miRNATAP -0.2 0.00055 NA
25 hsa-miR-429 AFF3 -2.17 0 1.16 0 MirTarget; PITA; miRanda; miRNATAP -0.31 0 NA
26 hsa-miR-429 AGAP2 -2.17 0 3.18 0 miRNATAP -0.63 0 NA
27 hsa-miR-429 AGAP3 -2.17 0 0.95 0 miRNATAP -0.16 0 NA
28 hsa-miR-429 AHR -2.17 0 0.76 0 miRanda -0.19 0 NA
29 hsa-miR-429 AHRR -2.17 0 0.99 0 miRanda -0.21 8.0E-5 NA
30 hsa-miR-429 AICDA -2.17 0 3.63 0 miRanda; miRNATAP -0.78 0 NA
31 hsa-miR-429 AKAP13 -2.17 0 0.53 0 miRNATAP -0.13 0 NA
32 hsa-miR-429 AKNA -2.17 0 1.43 0 miRanda -0.26 0 NA
33 hsa-miR-429 ALDH1L2 -2.17 0 0.98 0 miRanda -0.35 0 NA
34 hsa-miR-429 ANGPT2 -2.17 0 3.23 0 miRanda -0.72 0 NA
35 hsa-miR-429 ANKDD1A -2.17 0 0.82 0 miRanda -0.14 2.0E-5 NA
36 hsa-miR-429 ANKH -2.17 0 0.06 0.44279 PITA; miRanda; miRNATAP -0.11 0 NA
37 hsa-miR-429 ANKRD13B -2.17 0 1.36 0 miRNATAP -0.3 0 NA
38 hsa-miR-429 ANKRD34A -2.17 0 0.57 0 miRanda -0.15 0 NA
39 hsa-miR-429 ANKRD36B -2.17 0 1.11 0 miRanda -0.2 4.0E-5 NA
40 hsa-miR-429 ANKRD37 -2.17 0 1.44 0 miRanda -0.2 0 NA
41 hsa-miR-429 ANLN -2.17 0 2.52 0 MirTarget; PITA; miRanda; miRNATAP -0.61 0 NA
42 hsa-miR-429 ANO6 -2.17 0 0.26 0.00056 miRanda -0.12 0 NA
43 hsa-miR-429 ANTXR2 -2.17 0 0.22 0.02031 miRNATAP -0.15 0 NA
44 hsa-miR-429 ANXA4 -2.17 0 1.77 0 miRanda -0.26 0 NA
45 hsa-miR-429 AP1S2 -2.17 0 0.78 0 MirTarget; PITA; miRanda; miRNATAP -0.23 0 NA
46 hsa-miR-429 AP3S1 -2.17 0 1.02 0 miRanda -0.24 0 NA
47 hsa-miR-429 APAF1 -2.17 0 0.44 0 PITA; miRanda; miRNATAP -0.12 0 NA
48 hsa-miR-429 APBB3 -2.17 0 1.11 0 miRanda -0.16 7.0E-5 NA
49 hsa-miR-429 APLN -2.17 0 2.47 0 miRNATAP -0.46 0 NA
50 hsa-miR-429 AREG -2.17 0 1.08 0 miRanda -0.27 6.0E-5 NA
51 hsa-miR-429 ARHGAP1 -2.17 0 0.5 0 miRNATAP -0.1 0 NA
52 hsa-miR-429 ARHGAP10 -2.17 0 0.45 0 miRanda -0.1 0 NA
53 hsa-miR-429 ARHGAP11B -2.17 0 1.89 0 miRanda -0.46 0 NA
54 hsa-miR-429 ARHGAP15 -2.17 0 1.95 0 miRanda -0.37 0 NA
55 hsa-miR-429 ARHGAP17 -2.17 0 0.64 0 miRanda -0.14 0 NA
56 hsa-miR-429 ARHGAP20 -2.17 0 0.06 0.68409 MirTarget; miRanda; miRNATAP -0.16 0.00042 NA
57 hsa-miR-429 ARHGAP25 -2.17 0 1.75 0 miRNATAP -0.35 0 NA
58 hsa-miR-429 ARHGAP26 -2.17 0 1.01 0 PITA; miRNATAP -0.19 0 NA
59 hsa-miR-429 ARHGEF1 -2.17 0 1.07 0 miRanda; miRNATAP -0.19 0 NA
60 hsa-miR-429 ARHGEF10 -2.17 0 0.86 0 miRanda -0.22 0 NA
61 hsa-miR-429 ARHGEF17 -2.17 0 0.44 0 PITA; miRanda; miRNATAP -0.1 0.0001 NA
62 hsa-miR-429 ARHGEF2 -2.17 0 0.47 0 miRNATAP -0.12 0 NA
63 hsa-miR-429 ARHGEF6 -2.17 0 1.16 0 miRanda; mirMAP -0.28 0 NA
64 hsa-miR-429 ARHGEF7 -2.17 0 0.61 0 miRNATAP -0.11 0 NA
65 hsa-miR-429 ARL10 -2.17 0 0.82 0 mirMAP -0.14 0.00056 NA
66 hsa-miR-429 ARL4A -2.17 0 1.07 0 miRanda; miRNATAP -0.28 0 NA
67 hsa-miR-429 ARL4C -2.17 0 1.68 0 miRNATAP -0.39 0 NA
68 hsa-miR-429 ARL6IP6 -2.17 0 0.66 0 miRanda -0.19 0 NA
69 hsa-miR-429 ARRDC3 -2.17 0 0.27 0.025 PITA; miRanda; miRNATAP -0.15 2.0E-5 NA
70 hsa-miR-429 ASAP1 -2.17 0 1.03 0 MirTarget; miRanda; miRNATAP -0.27 0 NA
71 hsa-miR-429 ASCC3 -2.17 0 0.31 0.0001 miRanda -0.1 0 NA
72 hsa-miR-429 ATAD2 -2.17 0 0.83 0 miRanda -0.25 0 NA
73 hsa-miR-429 ATF7 -2.17 0 0.3 0 miRanda; miRNATAP -0.11 0 NA
74 hsa-miR-429 ATG12 -2.17 0 0.87 0 miRanda; miRNATAP -0.23 0 NA
75 hsa-miR-429 ATG16L1 -2.17 0 0.74 0 miRNATAP -0.12 2.0E-5 NA
76 hsa-miR-429 ATP11A -2.17 0 1.32 0 miRNATAP -0.21 0 NA
77 hsa-miR-429 ATP2B2 -2.17 0 3.14 0 miRanda; miRNATAP -0.55 0 NA
78 hsa-miR-429 ATXN1 -2.17 0 0.44 0 MirTarget; PITA; miRNATAP -0.13 0 NA
79 hsa-miR-429 ATXN2L -2.17 0 0.66 0 miRNATAP -0.13 0 NA
80 hsa-miR-429 B3GAT2 -2.17 0 0.81 0 mirMAP -0.11 0.01762 NA
81 hsa-miR-429 B4GALNT1 -2.17 0 2.43 0 miRNATAP -0.45 0 NA
82 hsa-miR-429 BASP1 -2.17 0 0.43 0.00976 PITA; miRanda; miRNATAP -0.19 7.0E-5 NA
83 hsa-miR-429 BAZ1A -2.17 0 1.2 0 miRanda -0.24 0 NA
84 hsa-miR-429 BBC3 -2.17 0 1.76 0 miRNATAP -0.27 0 NA
85 hsa-miR-429 BCAP29 -2.17 0 0.49 0 MirTarget; PITA; miRanda; miRNATAP -0.13 0 NA
86 hsa-miR-429 BCKDK -2.17 0 0.86 0 miRNATAP -0.11 0 NA
87 hsa-miR-429 BCL11A -2.17 0 1.46 0 miRanda; miRNATAP -0.27 0 NA
88 hsa-miR-429 BCL11B -2.17 0 1.57 0 PITA; miRanda; miRNATAP -0.31 0 NA
89 hsa-miR-429 BCL6 -2.17 0 0.85 0 miRanda -0.17 0 NA
90 hsa-miR-429 BHLHE22 -2.17 0 0.25 0.18937 miRanda -0.14 0.01006 NA
91 hsa-miR-429 BHLHE41 -2.17 0 2.99 0 MirTarget; miRanda; miRNATAP -0.56 0 NA
92 hsa-miR-429 BMP1 -2.17 0 1.88 0 miRNATAP -0.4 0 NA
93 hsa-miR-429 BMP2 -2.17 0 0.83 0 miRNATAP -0.12 0.00274 NA
94 hsa-miR-429 BMPER -2.17 0 0.59 0.00223 PITA; miRanda -0.21 0.00016 NA
95 hsa-miR-429 BNIP3 -2.17 0 1.46 0 miRanda -0.19 0 NA
96 hsa-miR-429 BRCA1 -2.17 0 0.79 0 miRanda; miRNATAP -0.21 0 NA
97 hsa-miR-429 BRCA2 -2.17 0 1.71 0 miRanda -0.43 0 NA
98 hsa-miR-429 BRWD3 -2.17 0 0.09 0.46985 miRanda; miRNATAP -0.1 0.00482 NA
99 hsa-miR-429 BTBD3 -2.17 0 0.23 0.00467 miRanda; miRNATAP -0.1 1.0E-5 NA
100 hsa-miR-429 BTF3 -2.17 0 0.46 0 miRanda -0.12 0 NA
101 hsa-miR-429 BTG1 -2.17 0 0.57 0 miRNATAP -0.13 0 NA
102 hsa-miR-429 BTLA -2.17 0 1.41 0 miRNATAP -0.28 0 NA
103 hsa-miR-429 BTN2A1 -2.17 0 0.61 0 miRanda -0.14 0 NA
104 hsa-miR-429 BUB1 -2.17 0 3.17 0 miRanda -0.72 0 NA
105 hsa-miR-429 C10orf105 -2.17 0 1.49 0 miRNATAP -0.29 0 NA
106 hsa-miR-429 C8orf46 -2.17 0 1.16 0 miRNATAP -0.14 0.01224 NA
107 hsa-miR-429 CACNA1C -2.17 0 0.72 0 MirTarget; PITA; miRanda; miRNATAP -0.18 6.0E-5 NA
108 hsa-miR-429 CACNA2D4 -2.17 0 1.51 0 miRanda -0.36 0 NA
109 hsa-miR-429 CACNB1 -2.17 0 1 0 miRNATAP -0.2 0 NA
110 hsa-miR-429 CALD1 -2.17 0 0.63 0 miRanda -0.19 0 NA
111 hsa-miR-429 CALU -2.17 0 0.68 0 MirTarget; PITA; miRanda -0.24 0 NA
112 hsa-miR-429 CAMK1D -2.17 0 1.04 0 mirMAP -0.23 0 NA
113 hsa-miR-429 CAMK2N2 -2.17 0 1.55 0 miRNATAP -0.3 0 NA
114 hsa-miR-429 CAMKK1 -2.17 0 1.41 0 miRNATAP -0.27 0 NA
115 hsa-miR-429 CAMKK2 -2.17 0 0.53 0 miRNATAP -0.11 0 NA
116 hsa-miR-429 CAMLG -2.17 0 0.7 0 miRanda -0.16 0 NA
117 hsa-miR-429 CANX -2.17 0 0.45 0 miRNATAP -0.11 0 NA
118 hsa-miR-429 CASP1 -2.17 0 1.75 0 miRanda -0.33 0 NA
119 hsa-miR-429 CAV2 -2.17 0 1.92 0 miRNATAP -0.37 0 NA
120 hsa-miR-429 CBFA2T3 -2.17 0 1.01 0 miRNATAP -0.18 1.0E-5 NA
121 hsa-miR-429 CBFB -2.17 0 0.6 0 miRNATAP -0.16 0 NA
122 hsa-miR-429 CBL -2.17 0 0.29 0.00024 MirTarget; PITA; mirMAP; miRNATAP -0.13 0 NA
123 hsa-miR-429 CCDC102B -2.17 0 1.2 0 miRanda -0.34 0 NA
124 hsa-miR-429 CCDC127 -2.17 0 0.95 0 miRanda -0.18 0 NA
125 hsa-miR-429 CCDC14 -2.17 0 0.85 0 miRanda -0.11 0.00031 NA
126 hsa-miR-429 CCDC142 -2.17 0 0.97 0 miRanda -0.16 0 NA
127 hsa-miR-429 CCDC144A -2.17 0 0.99 3.0E-5 miRanda -0.2 0.00378 NA
128 hsa-miR-429 CCDC18 -2.17 0 1.39 0 miRanda -0.24 0 NA
129 hsa-miR-429 CCDC36 -2.17 0 1 0 miRanda -0.23 1.0E-5 NA
130 hsa-miR-429 CCDC85A -2.17 0 0.9 0 miRanda; miRNATAP -0.2 1.0E-5 NA
131 hsa-miR-429 CCDC88A -2.17 0 0.98 0 miRNATAP -0.28 0 NA
132 hsa-miR-429 CCDC91 -2.17 0 -0.02 0.86858 miRanda -0.11 0.00465 NA
133 hsa-miR-429 CCL22 -2.17 0 1.74 0 miRNATAP -0.2 0.00297 NA
134 hsa-miR-429 CCNA2 -2.17 0 2.57 0 miRanda; miRNATAP -0.54 0 NA
135 hsa-miR-429 CCND2 -2.17 0 1.12 0 miRNATAP -0.23 0 NA
136 hsa-miR-429 CCNE2 -2.17 0 2.09 0 PITA; miRanda; miRNATAP -0.46 0 NA
137 hsa-miR-429 CCNL2 -2.17 0 1.29 0 PITA; miRanda -0.11 0.01956 NA
138 hsa-miR-429 CCR1 -2.17 0 1.09 0 miRanda; miRNATAP -0.26 0 NA
139 hsa-miR-429 CCR2 -2.17 0 1.62 0 miRanda -0.28 0 NA
140 hsa-miR-429 CCT6P1 -2.17 0 0.84 0 miRanda -0.18 0 NA
141 hsa-miR-429 CD109 -2.17 0 1.09 0 miRanda -0.31 0 NA
142 hsa-miR-429 CD160 -2.17 0 1.8 0 miRanda -0.27 0 NA
143 hsa-miR-429 CD163 -2.17 0 1.83 0 miRNATAP -0.46 0 NA
144 hsa-miR-429 CD1D -2.17 0 2.61 0 miRanda -0.47 0 NA
145 hsa-miR-429 CD34 -2.17 0 0.51 7.0E-5 miRanda -0.14 0.00011 NA
146 hsa-miR-429 CD4 -2.17 0 1.85 0 miRNATAP -0.37 0 NA
147 hsa-miR-429 CD40LG -2.17 0 1.88 0 miRanda -0.39 0 NA
148 hsa-miR-429 CD69 -2.17 0 1.36 0 miRNATAP -0.3 0 NA
149 hsa-miR-429 CD70 -2.17 0 7.36 0 miRanda -1.45 0 NA
150 hsa-miR-429 CD72 -2.17 0 2.55 0 miRNATAP -0.49 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 190 1672 8.477e-24 3.944e-20
2 IMMUNE SYSTEM PROCESS 209 1984 4.285e-22 9.97e-19
3 REGULATION OF CELL PROLIFERATION 170 1496 3.14e-21 4.871e-18
4 POSITIVE REGULATION OF RESPONSE TO STIMULUS 200 1929 2.701e-20 3.142e-17
5 REGULATION OF CELL DIFFERENTIATION 164 1492 5.044e-19 4.694e-16
6 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 144 1275 9.559e-18 7.413e-15
7 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 172 1656 1.797e-17 8.589e-15
8 LOCOMOTION 131 1114 1.325e-17 8.589e-15
9 VASCULATURE DEVELOPMENT 75 469 1.953e-17 8.589e-15
10 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 123 1021 2.215e-17 8.589e-15
11 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 120 983 2.045e-17 8.589e-15
12 BIOLOGICAL ADHESION 124 1032 1.991e-17 8.589e-15
13 REGULATION OF CELLULAR COMPONENT MOVEMENT 102 771 2.793e-17 9.997e-15
14 BLOOD VESSEL MORPHOGENESIS 64 364 4.12e-17 1.369e-14
15 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 151 1395 6.379e-17 1.979e-14
16 TISSUE DEVELOPMENT 160 1518 7.689e-17 2.236e-14
17 CARDIOVASCULAR SYSTEM DEVELOPMENT 102 788 1.262e-16 3.261e-14
18 CIRCULATORY SYSTEM DEVELOPMENT 102 788 1.262e-16 3.261e-14
19 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 130 1142 2.472e-16 6.053e-14
20 REGULATION OF NEURON DIFFERENTIATION 79 554 2.117e-15 4.925e-13
21 REGULATION OF CELL DEVELOPMENT 103 836 2.541e-15 5.63e-13
22 IMMUNE SYSTEM DEVELOPMENT 81 582 3.708e-15 7.843e-13
23 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 95 750 5.97e-15 1.208e-12
24 POSITIVE REGULATION OF CELL PROLIFERATION 100 814 8.063e-15 1.563e-12
25 CELL ACTIVATION 79 568 8.554e-15 1.592e-12
26 CELL MOTILITY 101 835 1.602e-14 2.761e-12
27 LOCALIZATION OF CELL 101 835 1.602e-14 2.761e-12
28 POSITIVE REGULATION OF CELL COMMUNICATION 154 1532 1.96e-14 3.257e-12
29 ANGIOGENESIS 52 293 2.616e-14 4.197e-12
30 REGULATION OF CELL ADHESION 83 629 3.532e-14 5.478e-12
31 CELL CELL ADHESION 81 608 4.309e-14 6.468e-12
32 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 150 1492 4.487e-14 6.524e-12
33 CELL DEVELOPMENT 145 1426 5.164e-14 7.282e-12
34 NEUROGENESIS 143 1402 6.215e-14 8.505e-12
35 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 114 1036 2.131e-13 2.68e-11
36 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 114 1036 2.131e-13 2.68e-11
37 REGULATION OF PHOSPHORUS METABOLIC PROCESS 157 1618 2.057e-13 2.68e-11
38 SINGLE ORGANISM CELL ADHESION 66 459 3.143e-13 3.848e-11
39 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 101 876 3.32e-13 3.961e-11
40 POSITIVE REGULATION OF CELL DIFFERENTIATION 96 823 6.72e-13 7.817e-11
41 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 94 801 8.356e-13 9.483e-11
42 POSITIVE REGULATION OF GENE EXPRESSION 163 1733 9.087e-13 1.007e-10
43 POSITIVE REGULATION OF CATALYTIC ACTIVITY 147 1518 1.602e-12 1.733e-10
44 REGULATION OF IMMUNE SYSTEM PROCESS 138 1403 2.758e-12 2.917e-10
45 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 166 1805 3.5e-12 3.614e-10
46 POSITIVE REGULATION OF MOLECULAR FUNCTION 165 1791 3.573e-12 3.614e-10
47 LEUKOCYTE DIFFERENTIATION 48 292 4.739e-12 4.692e-10
48 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 104 957 5.692e-12 5.518e-10
49 LEUKOCYTE ACTIVATION 59 414 8.513e-12 8.084e-10
50 REGULATION OF PROTEIN MODIFICATION PROCESS 158 1710 8.92e-12 8.301e-10
51 LYMPHOCYTE ACTIVATION 52 342 1.301e-11 1.187e-09
52 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 96 867 1.383e-11 1.238e-09
53 REGULATION OF NEURON PROJECTION DEVELOPMENT 58 408 1.422e-11 1.248e-09
54 RESPONSE TO EXTERNAL STIMULUS 164 1821 2.593e-11 2.235e-09
55 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 115 1135 3.622e-11 3.064e-09
56 NEGATIVE REGULATION OF CELL PROLIFERATION 77 643 4.103e-11 3.409e-09
57 REGULATION OF CELL DEATH 139 1472 4.303e-11 3.513e-09
58 INTRACELLULAR SIGNAL TRANSDUCTION 145 1572 8.379e-11 6.722e-09
59 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 130 1360 8.948e-11 7.056e-09
60 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 104 1004 9.691e-11 7.515e-09
61 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 159 1784 1.219e-10 9.301e-09
62 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 65 513 1.347e-10 1.011e-08
63 REGULATION OF MAPK CASCADE 77 660 1.433e-10 1.058e-08
64 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 163 1848 1.509e-10 1.097e-08
65 REGULATION OF KINASE ACTIVITY 86 776 1.637e-10 1.172e-08
66 REGULATION OF HOMOTYPIC CELL CELL ADHESION 46 307 3.269e-10 2.305e-08
67 LEUKOCYTE CELL CELL ADHESION 41 255 3.447e-10 2.394e-08
68 REGULATION OF AXONOGENESIS 32 168 3.905e-10 2.672e-08
69 RESPONSE TO WOUNDING 68 563 4.069e-10 2.744e-08
70 POSITIVE REGULATION OF CELL ADHESION 52 376 4.478e-10 2.976e-08
71 POSITIVE REGULATION OF MAPK CASCADE 60 470 5.218e-10 3.419e-08
72 POSITIVE REGULATION OF CELL DEATH 71 605 5.929e-10 3.831e-08
73 RESPONSE TO ABIOTIC STIMULUS 103 1024 6.277e-10 3.972e-08
74 MESENCHYME DEVELOPMENT 34 190 6.317e-10 3.972e-08
75 REGULATION OF CELL CELL ADHESION 52 380 6.56e-10 4.07e-08
76 TISSUE MORPHOGENESIS 65 533 6.721e-10 4.115e-08
77 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 48 337 7.78e-10 4.702e-08
78 NEGATIVE REGULATION OF CELL DIFFERENTIATION 71 609 7.91e-10 4.719e-08
79 HEART DEVELOPMENT 59 466 1.004e-09 5.913e-08
80 REGULATION OF CELL MORPHOGENESIS 66 552 1.129e-09 6.565e-08
81 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 85 799 1.57e-09 9.021e-08
82 REGULATION OF CELL ACTIVATION 60 484 1.645e-09 9.221e-08
83 POSITIVE REGULATION OF CELL DEVELOPMENT 59 472 1.642e-09 9.221e-08
84 REGULATION OF CELL PROJECTION ORGANIZATION 66 558 1.762e-09 9.762e-08
85 REGULATION OF IMMUNE RESPONSE 89 858 2.233e-09 1.222e-07
86 REGULATION OF CHEMOTAXIS 32 180 2.377e-09 1.286e-07
87 MESENCHYMAL CELL DIFFERENTIATION 27 134 2.522e-09 1.349e-07
88 NEGATIVE REGULATION OF CELL COMMUNICATION 113 1192 2.8e-09 1.481e-07
89 POSITIVE REGULATION OF NEURON DIFFERENTIATION 44 306 2.941e-09 1.538e-07
90 REGULATION OF EPITHELIAL CELL PROLIFERATION 42 285 3.196e-09 1.652e-07
91 POSITIVE REGULATION OF HYDROLASE ACTIVITY 92 905 3.256e-09 1.665e-07
92 REGULATION OF VASCULATURE DEVELOPMENT 37 233 3.538e-09 1.789e-07
93 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 55 437 4.622e-09 2.312e-07
94 TAXIS 57 464 5.899e-09 2.92e-07
95 SPROUTING ANGIOGENESIS 15 45 6.65e-09 3.257e-07
96 IMMUNE RESPONSE 105 1100 7.444e-09 3.608e-07
97 EMBRYO DEVELOPMENT 90 894 7.824e-09 3.753e-07
98 LYMPHOCYTE DIFFERENTIATION 34 209 8.104e-09 3.848e-07
99 ORGAN MORPHOGENESIS 86 841 8.285e-09 3.894e-07
100 POSITIVE REGULATION OF KINASE ACTIVITY 58 482 9.273e-09 4.315e-07
101 CELL PROLIFERATION 73 672 9.803e-09 4.516e-07
102 REGULATION OF CELL SIZE 30 172 1.181e-08 5.39e-07
103 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 48 368 1.432e-08 6.469e-07
104 POSITIVE REGULATION OF CELL ACTIVATION 43 311 1.459e-08 6.527e-07
105 REGULATION OF EXTENT OF CELL GROWTH 22 101 1.677e-08 7.43e-07
106 REGULATION OF EPITHELIAL CELL MIGRATION 29 166 1.988e-08 8.727e-07
107 RESPONSE TO OXYGEN CONTAINING COMPOUND 123 1381 2.128e-08 9.253e-07
108 WOUND HEALING 56 470 2.368e-08 1.02e-06
109 NEURON PROJECTION DEVELOPMENT 62 545 2.419e-08 1.033e-06
110 EPITHELIUM DEVELOPMENT 92 945 2.673e-08 1.131e-06
111 REGULATION OF ANATOMICAL STRUCTURE SIZE 56 472 2.747e-08 1.151e-06
112 REGULATION OF TRANSFERASE ACTIVITY 92 946 2.811e-08 1.168e-06
113 CYTOSKELETON ORGANIZATION 84 838 3.072e-08 1.265e-06
114 NEURON PROJECTION MORPHOGENESIS 50 402 3.418e-08 1.383e-06
115 STEM CELL DIFFERENTIATION 31 190 3.419e-08 1.383e-06
116 POSITIVE REGULATION OF CELL CELL ADHESION 36 243 3.676e-08 1.475e-06
117 REGULATION OF T HELPER CELL DIFFERENTIATION 11 26 3.988e-08 1.586e-06
118 NEURON DIFFERENTIATION 86 874 4.839e-08 1.908e-06
119 CELLULAR RESPONSE TO BIOTIC STIMULUS 28 163 5.057e-08 1.977e-06
120 ENDOTHELIUM DEVELOPMENT 20 90 5.222e-08 2.025e-06
121 POSITIVE REGULATION OF LOCOMOTION 51 420 5.457e-08 2.099e-06
122 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 55 470 5.844e-08 2.229e-06
123 EXTRACELLULAR STRUCTURE ORGANIZATION 41 304 6.372e-08 2.411e-06
124 CHONDROCYTE DIFFERENTIATION 16 60 7.478e-08 2.806e-06
125 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 37 262 8.485e-08 3.158e-06
126 CENTRAL NERVOUS SYSTEM DEVELOPMENT 85 872 8.799e-08 3.249e-06
127 CELLULAR COMPONENT MORPHOGENESIS 87 900 8.946e-08 3.278e-06
128 NEGATIVE REGULATION OF LOCOMOTION 37 263 9.372e-08 3.407e-06
129 CELL CYCLE 116 1316 9.75e-08 3.517e-06
130 CELL PROJECTION ORGANIZATION 87 902 9.873e-08 3.534e-06
131 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 42 321 1.045e-07 3.712e-06
132 NEURON DEVELOPMENT 71 687 1.153e-07 4.063e-06
133 POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION 9 18 1.189e-07 4.161e-06
134 REGULATION OF DEVELOPMENTAL GROWTH 39 289 1.309e-07 4.545e-06
135 CELLULAR RESPONSE TO LIPID 53 457 1.363e-07 4.698e-06
136 REGULATION OF ENDOTHELIAL CELL MIGRATION 22 114 1.662e-07 5.686e-06
137 MORPHOGENESIS OF AN EPITHELIUM 48 400 1.92e-07 6.522e-06
138 RESPONSE TO GROWTH FACTOR 54 475 1.993e-07 6.721e-06
139 REGULATION OF LEUKOCYTE PROLIFERATION 31 206 2.253e-07 7.54e-06
140 CELL CYCLE PROCESS 98 1081 2.896e-07 9.626e-06
141 RESPONSE TO ENDOGENOUS STIMULUS 123 1450 3.137e-07 1.028e-05
142 MORPHOGENESIS OF A BRANCHING STRUCTURE 27 167 3.121e-07 1.028e-05
143 MUSCLE STRUCTURE DEVELOPMENT 50 432 3.274e-07 1.065e-05
144 REGULATION OF T HELPER 2 CELL DIFFERENTIATION 7 11 3.602e-07 1.16e-05
145 MYELOID CELL DIFFERENTIATION 29 189 3.616e-07 1.16e-05
146 CELL DEATH 92 1001 3.748e-07 1.186e-05
147 REGULATION OF TRANSPORT 146 1804 3.745e-07 1.186e-05
148 RESPONSE TO LIPID 84 888 3.774e-07 1.186e-05
149 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 37 278 3.876e-07 1.21e-05
150 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 18 84 4.301e-07 1.317e-05
151 REGULATION OF HEMOPOIESIS 40 314 4.262e-07 1.317e-05
152 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 12 38 4.279e-07 1.317e-05
153 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 29 191 4.534e-07 1.363e-05
154 TUBE DEVELOPMENT 59 552 4.541e-07 1.363e-05
155 RESPONSE TO REACTIVE OXYGEN SPECIES 29 191 4.534e-07 1.363e-05
156 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 73 740 4.693e-07 1.4e-05
157 REGULATION OF ALPHA BETA T CELL ACTIVATION 16 68 4.883e-07 1.443e-05
158 REGULATION OF TYPE 2 IMMUNE RESPONSE 10 26 4.899e-07 1.443e-05
159 ENDOCARDIAL CUSHION DEVELOPMENT 11 32 4.933e-07 1.444e-05
160 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 59 554 5.124e-07 1.49e-05
161 NEGATIVE REGULATION OF GROWTH 33 236 5.278e-07 1.525e-05
162 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 69 689 5.633e-07 1.618e-05
163 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 13 46 5.994e-07 1.711e-05
164 CONNECTIVE TISSUE DEVELOPMENT 29 194 6.323e-07 1.794e-05
165 REGULATION OF MAP KINASE ACTIVITY 40 319 6.443e-07 1.815e-05
166 NEURON PROJECTION GUIDANCE 30 205 6.474e-07 1.815e-05
167 T CELL DIFFERENTIATION 22 123 6.58e-07 1.833e-05
168 NEGATIVE REGULATION OF CELL DEATH 82 872 6.64e-07 1.839e-05
169 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 23 133 6.865e-07 1.89e-05
170 LYMPHOCYTE COSTIMULATION 17 78 6.947e-07 1.902e-05
171 POSITIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 10 27 7.405e-07 2.015e-05
172 FOREBRAIN DEVELOPMENT 43 357 7.475e-07 2.022e-05
173 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 144 7.937e-07 2.135e-05
174 REGULATION OF HYDROLASE ACTIVITY 113 1327 8.23e-07 2.201e-05
175 MUSCLE TISSUE DEVELOPMENT 36 275 8.296e-07 2.206e-05
176 POSITIVE REGULATION OF IMMUNE RESPONSE 59 563 8.731e-07 2.308e-05
177 TUBE MORPHOGENESIS 40 323 8.896e-07 2.336e-05
178 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 54 498 8.936e-07 2.336e-05
179 CELL CELL SIGNALING 74 767 9.129e-07 2.373e-05
180 HEART VALVE DEVELOPMENT 11 34 9.899e-07 2.559e-05
181 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 23 136 1.03e-06 2.647e-05
182 RESPONSE TO MECHANICAL STIMULUS 30 210 1.088e-06 2.781e-05
183 ACTIVATION OF PROTEIN KINASE ACTIVITY 36 279 1.174e-06 2.985e-05
184 NEGATIVE REGULATION OF CELL DEVELOPMENT 38 303 1.216e-06 3.074e-05
185 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 42 352 1.286e-06 3.234e-05
186 RESPONSE TO ORGANIC CYCLIC COMPOUND 84 917 1.408e-06 3.521e-05
187 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 62 616 1.798e-06 4.475e-05
188 REGULATION OF ERK1 AND ERK2 CASCADE 32 238 1.866e-06 4.618e-05
189 SEMAPHORIN PLEXIN SIGNALING PATHWAY 11 36 1.881e-06 4.632e-05
190 NEURAL CREST CELL DIFFERENTIATION 16 75 1.988e-06 4.869e-05
191 TELENCEPHALON DEVELOPMENT 31 228 2.119e-06 5.163e-05
192 PLATELET ACTIVATION 23 142 2.227e-06 5.369e-05
193 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 28 195 2.22e-06 5.369e-05
194 POSITIVE REGULATION OF CELL CYCLE ARREST 17 85 2.474e-06 5.933e-05
195 ACTIN FILAMENT BASED PROCESS 49 450 2.53e-06 6.037e-05
196 POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 11 37 2.547e-06 6.047e-05
197 CELL CYCLE PHASE TRANSITION 33 255 3.034e-06 7.167e-05
198 REGULATION OF LEUKOCYTE DIFFERENTIATION 31 232 3.068e-06 7.209e-05
199 HEAD DEVELOPMENT 68 709 3.118e-06 7.291e-05
200 CEREBRAL CORTEX DEVELOPMENT 19 105 3.134e-06 7.292e-05
201 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 10 31 3.193e-06 7.392e-05
202 POSITIVE REGULATION OF AXONOGENESIS 15 69 3.223e-06 7.423e-05
203 POSITIVE REGULATION OF TYPE 2 IMMUNE RESPONSE 7 14 3.244e-06 7.436e-05
204 NEGATIVE REGULATION OF AXON EXTENSION 11 38 3.411e-06 7.779e-05
205 SKELETAL SYSTEM DEVELOPMENT 49 455 3.453e-06 7.837e-05
206 CARTILAGE DEVELOPMENT 23 147 4.08e-06 9.217e-05
207 REGULATION OF T CELL DIFFERENTIATION 19 107 4.191e-06 9.42e-05
208 REGULATION OF GROWTH 62 633 4.364e-06 9.763e-05
209 PATTERNING OF BLOOD VESSELS 10 32 4.42e-06 9.794e-05
210 PROTEIN PHOSPHORYLATION 84 944 4.408e-06 9.794e-05
211 POSITIVE REGULATION OF CELL CYCLE 39 332 4.457e-06 9.828e-05
212 REGULATION OF AXON GUIDANCE 11 39 4.52e-06 9.92e-05
213 REGULATION OF CARTILAGE DEVELOPMENT 14 63 5.189e-06 0.0001134
214 CELLULAR RESPONSE TO STRESS 125 1565 5.492e-06 0.0001194
215 RESPONSE TO MURAMYL DIPEPTIDE 7 15 5.798e-06 0.0001251
216 RESPONSE TO OXYGEN LEVELS 37 311 5.807e-06 0.0001251
217 OSSIFICATION 32 251 5.857e-06 0.0001256
218 CELL CYCLE CHECKPOINT 27 194 6.09e-06 0.00013
219 MITOTIC CELL CYCLE 71 766 6.26e-06 0.000133
220 REGULATION OF CELLULAR COMPONENT SIZE 39 337 6.375e-06 0.0001348
221 REGULATION OF INTERLEUKIN 2 PRODUCTION 12 48 6.667e-06 0.0001404
222 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 162 6.708e-06 0.0001406
223 INFLAMMATORY RESPONSE 48 454 7.153e-06 0.0001491
224 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 21 131 7.176e-06 0.0001491
225 CELL CYCLE G1 S PHASE TRANSITION 19 111 7.318e-06 0.0001507
226 G1 S TRANSITION OF MITOTIC CELL CYCLE 19 111 7.318e-06 0.0001507
227 RESPONSE TO OXIDATIVE STRESS 40 352 7.574e-06 0.0001553
228 CHONDROCYTE DEVELOPMENT 8 21 7.678e-06 0.000156
229 NEGATIVE REGULATION OF AXONOGENESIS 14 65 7.652e-06 0.000156
230 REGULATION OF GTPASE ACTIVITY 64 673 7.999e-06 0.0001618
231 REGULATION OF CYTOKINE PRODUCTION 56 563 8.051e-06 0.0001622
232 REGULATION OF CELL CYCLE 83 949 9.636e-06 0.0001933
233 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 87 1008 9.75e-06 0.0001947
234 POSITIVE REGULATION OF TRANSPORT 82 936 1.026e-05 0.0002041
235 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 18 104 1.079e-05 0.0002136
236 LEUKOCYTE MIGRATION 32 259 1.127e-05 0.0002222
237 HEART MORPHOGENESIS 28 212 1.133e-05 0.0002225
238 T CELL RECEPTOR SIGNALING PATHWAY 22 146 1.218e-05 0.0002361
239 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 22 146 1.218e-05 0.0002361
240 DNA INTEGRITY CHECKPOINT 22 146 1.218e-05 0.0002361
241 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 81 926 1.23e-05 0.0002375
242 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 11 43 1.271e-05 0.0002444
243 NEGATIVE REGULATION OF CHEMOTAXIS 12 51 1.307e-05 0.0002493
244 POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 12 51 1.307e-05 0.0002493
245 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 120 1517 1.347e-05 0.0002558
246 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 96 1152 1.406e-05 0.0002658
247 IN UTERO EMBRYONIC DEVELOPMENT 36 311 1.422e-05 0.000268
248 TISSUE REMODELING 16 87 1.496e-05 0.0002807
249 NEGATIVE REGULATION OF CELL GROWTH 24 170 1.542e-05 0.0002882
250 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 19 117 1.599e-05 0.0002977
251 ADAPTIVE IMMUNE RESPONSE 34 288 1.614e-05 0.0002993
252 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 6 12 1.714e-05 0.0003165
253 REGULATION OF STEM CELL PROLIFERATION 16 88 1.738e-05 0.0003196
254 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 17 98 1.825e-05 0.000333
255 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 17 98 1.825e-05 0.000333
256 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 15 79 1.846e-05 0.0003343
257 REGULATION OF CELL CYCLE ARREST 18 108 1.845e-05 0.0003343
258 AXON EXTENSION 10 37 1.864e-05 0.0003362
259 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 14 70 1.884e-05 0.0003371
260 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 14 70 1.884e-05 0.0003371
261 SMOOTH MUSCLE CELL DIFFERENTIATION 9 30 1.942e-05 0.0003434
262 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 9 30 1.942e-05 0.0003434
263 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 9 30 1.942e-05 0.0003434
264 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 35 303 1.948e-05 0.0003434
265 NEURON PROJECTION EXTENSION 12 53 1.988e-05 0.0003491
266 CENTROSOME CYCLE 11 45 2.031e-05 0.0003552
267 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 18 109 2.1e-05 0.0003659
268 CARDIAC VENTRICLE MORPHOGENESIS 13 62 2.187e-05 0.0003796
269 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 29 232 2.297e-05 0.0003973
270 REGULATION OF GLIOGENESIS 16 90 2.328e-05 0.0004012
271 CELL SUBSTRATE ADHESION 23 164 2.566e-05 0.0004396
272 PALLIUM DEVELOPMENT 22 153 2.579e-05 0.0004396
273 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 22 153 2.579e-05 0.0004396
274 REGULATION OF CELLULAR LOCALIZATION 103 1277 2.631e-05 0.0004469
275 RESPONSE TO NITROGEN COMPOUND 75 859 2.758e-05 0.000465
276 REGULATION OF LYMPHOCYTE DIFFERENTIATION 20 132 2.754e-05 0.000465
277 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 6 13 3.038e-05 0.0005103
278 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 14 73 3.098e-05 0.0005185
279 ACTIVATION OF IMMUNE RESPONSE 44 427 3.192e-05 0.0005323
280 CELL PART MORPHOGENESIS 59 633 3.232e-05 0.0005351
281 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 36 323 3.229e-05 0.0005351
282 MEMBRANE ASSEMBLY 8 25 3.362e-05 0.0005528
283 CHONDROITIN SULFATE BIOSYNTHETIC PROCESS 8 25 3.362e-05 0.0005528
284 ANTIGEN PROCESSING AND PRESENTATION 27 213 3.389e-05 0.0005553
285 PROTEOGLYCAN METABOLIC PROCESS 15 83 3.403e-05 0.0005555
286 MUSCLE CELL DIFFERENTIATION 29 237 3.425e-05 0.0005573
287 TISSUE MIGRATION 15 84 3.938e-05 0.0006363
288 MICROTUBULE ORGANIZING CENTER ORGANIZATION 15 84 3.938e-05 0.0006363
289 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 33 289 4.201e-05 0.0006763
290 ARTERY DEVELOPMENT 14 75 4.247e-05 0.0006815
291 NEGATIVE REGULATION OF CELL ACTIVATION 22 158 4.266e-05 0.0006821
292 RESPONSE TO BACTERIUM 51 528 4.401e-05 0.0007013
293 NEGATIVE REGULATION OF CELL CYCLE 44 433 4.457e-05 0.0007078
294 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 11 49 4.779e-05 0.0007564
295 REGULATION OF RESPONSE TO STRESS 114 1468 4.95e-05 0.0007782
296 EXTRACELLULAR MATRIX DISASSEMBLY 14 76 4.951e-05 0.0007782
297 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 6 14 5.073e-05 0.0007948
298 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 19 127 5.18e-05 0.0008089
299 POSITIVE REGULATION OF CYTOKINE PRODUCTION 39 370 5.393e-05 0.0008393
300 LEUKOCYTE CHEMOTAXIS 18 117 5.562e-05 0.0008627
301 DEVELOPMENTAL CELL GROWTH 14 77 5.754e-05 0.0008895
302 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 10 42 6.154e-05 0.0009482
303 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 8 27 6.266e-05 0.0009622
304 NEGATIVE REGULATION OF GENE EXPRESSION 115 1493 6.445e-05 0.0009865
305 CARDIAC MUSCLE TISSUE DEVELOPMENT 20 140 6.497e-05 0.0009879
306 REGULATION OF ION TRANSPORT 55 592 6.478e-05 0.0009879
307 ACTIN FILAMENT ORGANIZATION 23 174 6.597e-05 0.0009999
308 POSITIVE REGULATION OF HEMOPOIESIS 22 163 6.88e-05 0.001039
309 PROTEIN COMPLEX SUBUNIT ORGANIZATION 117 1527 6.925e-05 0.001043
310 ARTERY MORPHOGENESIS 11 51 7.074e-05 0.001058
311 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 11 51 7.074e-05 0.001058
312 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 724 7.444e-05 0.001107
313 RESPONSE TO HYDROGEN PEROXIDE 17 109 7.445e-05 0.001107
314 CEREBRAL CORTEX CELL MIGRATION 10 43 7.634e-05 0.001131
315 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 19 131 7.967e-05 0.001177
316 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 6 15 8.069e-05 0.001188
317 UROGENITAL SYSTEM DEVELOPMENT 33 299 8.205e-05 0.001204
318 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN 23 177 8.607e-05 0.001252
319 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 21 154 8.586e-05 0.001252
320 AMEBOIDAL TYPE CELL MIGRATION 21 154 8.586e-05 0.001252
321 RAS PROTEIN SIGNAL TRANSDUCTION 20 143 8.787e-05 0.00127
322 MITOTIC DNA INTEGRITY CHECKPOINT 16 100 8.791e-05 0.00127
323 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 14 80 8.884e-05 0.00128
324 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 22 166 9.061e-05 0.001301
325 CIRCULATORY SYSTEM PROCESS 38 366 9.211e-05 0.001319
326 REGULATION OF OSSIFICATION 23 178 9.389e-05 0.00134
327 POSITIVE REGULATION OF AXON EXTENSION 9 36 9.53e-05 0.001352
328 T CELL SELECTION 9 36 9.53e-05 0.001352
329 NEGATIVE REGULATION OF CELL CYCLE PROCESS 26 214 9.623e-05 0.001361
330 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 16 101 9.93e-05 0.0014
331 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 23 179 0.0001023 0.001439
332 FOREBRAIN CELL MIGRATION 12 62 0.0001027 0.00144
333 SYNAPSE ORGANIZATION 20 145 0.0001069 0.001493
334 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 7 22 0.00011 0.001528
335 POSITIVE REGULATION OF INTERLEUKIN 4 PRODUCTION 7 22 0.00011 0.001528
336 ENDOTHELIAL CELL DIFFERENTIATION 13 72 0.000113 0.001565
337 ATRIOVENTRICULAR VALVE MORPHOGENESIS 6 16 0.0001232 0.001701
338 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 16 103 0.000126 0.001735
339 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 20 147 0.0001294 0.001776
340 EPITHELIAL CELL DIFFERENTIATION 47 495 0.0001301 0.001781
341 G1 DNA DAMAGE CHECKPOINT 13 73 0.0001308 0.001785
342 MULTICELLULAR ORGANISM METABOLIC PROCESS 15 93 0.0001319 0.001794
343 CARDIAC CHAMBER MORPHOGENESIS 16 104 0.0001416 0.001909
344 REGULATION OF INTERLEUKIN 6 PRODUCTION 16 104 0.0001416 0.001909
345 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 16 104 0.0001416 0.001909
346 MEMBRANE BIOGENESIS 8 30 0.0001429 0.001917
347 OSTEOCLAST DIFFERENTIATION 8 30 0.0001429 0.001917
348 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 17 115 0.0001468 0.001962
349 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE OR POLYSACCHARIDE ANTIGEN VIA MHC CLASS II 15 94 0.0001492 0.001983
350 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS II 15 94 0.0001492 0.001983
351 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 9 38 0.0001497 0.001984
352 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 13 74 0.000151 0.001995
353 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 32 296 0.0001537 0.002014
354 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 22 172 0.0001534 0.002014
355 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 60 684 0.0001529 0.002014
356 CELLULAR RESPONSE TO OXIDATIVE STRESS 23 184 0.0001556 0.002033
357 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 27 233 0.0001587 0.002069
358 POSITIVE REGULATION OF T CELL PROLIFERATION 15 95 0.0001684 0.002187
359 CELL JUNCTION ORGANIZATION 23 185 0.0001688 0.002187
360 EPITHELIAL TO MESENCHYMAL TRANSITION 11 56 0.0001727 0.002232
361 HEMOSTASIS 33 311 0.0001736 0.002238
362 POSITIVE REGULATION OF CELL CYCLE PROCESS 28 247 0.0001761 0.002263
363 REGULATION OF CELL CYCLE PROCESS 51 558 0.0001766 0.002264
364 CELL CHEMOTAXIS 21 162 0.0001778 0.002272
365 REGULATION OF INTERLEUKIN 4 PRODUCTION 8 31 0.0001836 0.00234
366 NEGATIVE CHEMOTAXIS 9 39 0.0001853 0.002356
367 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 30 274 0.0001951 0.002474
368 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 10 48 0.0002037 0.002555
369 ENDOTHELIAL CELL MIGRATION 11 57 0.0002037 0.002555
370 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 7 24 0.000203 0.002555
371 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 7 24 0.000203 0.002555
372 RESPONSE TO BIOTIC STIMULUS 73 886 0.000215 0.002689
373 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 12 67 0.0002224 0.002767
374 MUCOPOLYSACCHARIDE METABOLIC PROCESS 16 108 0.0002218 0.002767
375 SENSORY ORGAN DEVELOPMENT 46 493 0.0002275 0.002822
376 GROWTH 40 410 0.0002307 0.002855
377 BLOOD VESSEL REMODELING 8 32 0.0002333 0.002879
378 MUSCLE ORGAN DEVELOPMENT 30 277 0.000236 0.002905
379 POSITIVE REGULATION OF CHEMOTAXIS 17 120 0.000248 0.003044
380 CELL FATE COMMITMENT 26 227 0.0002508 0.003071
381 CELLULAR RESPONSE TO HORMONE STIMULUS 50 552 0.0002521 0.003078
382 LEUKOCYTE PROLIFERATION 14 88 0.0002535 0.003088
383 REGULATION OF CELL JUNCTION ASSEMBLY 12 68 0.000257 0.003114
384 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 12 68 0.000257 0.003114
385 REGULATION OF TOLL LIKE RECEPTOR 4 SIGNALING PATHWAY 6 18 0.0002602 0.003144
386 REGULATION OF MITOTIC CELL CYCLE 44 468 0.0002617 0.003155
387 EMBRYONIC MORPHOGENESIS 49 539 0.0002661 0.0032
388 DEFENSE RESPONSE 95 1231 0.0002672 0.003204
389 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 18 132 0.000268 0.003206
390 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 24 204 0.0002865 0.003418
391 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 26 229 0.0002881 0.003428
392 BONE DEVELOPMENT 20 156 0.0002911 0.003438
393 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 20 156 0.0002911 0.003438
394 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 20 156 0.0002911 0.003438
395 LOCALIZATION WITHIN MEMBRANE 17 122 0.0003029 0.003568
396 RESPONSE TO IONIZING RADIATION 19 145 0.0003087 0.003627
397 PATTERN SPECIFICATION PROCESS 40 418 0.0003427 0.004017
398 REGULATION OF CELL GROWTH 38 391 0.0003527 0.004124
399 POSITIVE REGULATION OF MAP KINASE ACTIVITY 24 207 0.0003561 0.004153
400 REGULATION OF CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 6 19 0.0003629 0.004211
401 ATRIOVENTRICULAR VALVE DEVELOPMENT 6 19 0.0003629 0.004211
402 REGULATION OF CELLULAR COMPONENT BIOGENESIS 64 767 0.0003718 0.004304
403 PROTEIN OLIGOMERIZATION 41 434 0.0003789 0.004353
404 POSITIVE REGULATION OF STEM CELL PROLIFERATION 11 61 0.0003788 0.004353
405 PHOSPHORYLATION 94 1228 0.0003787 0.004353
406 REGULATION OF PROTEIN LOCALIZATION 76 950 0.00039 0.004469
407 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 22 184 0.0004025 0.004602
408 ACTIVATION OF MAPKK ACTIVITY 10 52 0.0004049 0.004618
409 POSITIVE REGULATION OF INTERLEUKIN 13 PRODUCTION 5 13 0.0004084 0.004646
410 NOTCH SIGNALING PATHWAY 16 114 0.0004151 0.004701
411 NEGATIVE REGULATION OF PHOSPHORYLATION 40 422 0.0004152 0.004701
412 REGULATION OF MUSCLE ORGAN DEVELOPMENT 15 103 0.0004165 0.004704
413 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 13 82 0.0004316 0.004862
414 REGULATION OF LEUKOCYTE MIGRATION 19 149 0.0004372 0.004902
415 CELLULAR RESPONSE TO PEPTIDE 29 274 0.0004362 0.004902
416 MOTOR NEURON AXON GUIDANCE 7 27 0.0004519 0.00503
417 NEGATIVE REGULATION OF AXON GUIDANCE 7 27 0.0004519 0.00503
418 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 27 0.0004519 0.00503
419 NEPHRON DEVELOPMENT 16 115 0.0004585 0.005092
420 NEGATIVE REGULATION OF CELL CELL ADHESION 18 138 0.0004649 0.005139
421 CELL CYCLE G2 M PHASE TRANSITION 18 138 0.0004649 0.005139
422 RESPONSE TO CYTOKINE 60 714 0.0004697 0.005179
423 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 10 53 0.0004753 0.005228
424 POSITIVE REGULATION OF SECRETION 36 370 0.0004878 0.005353
425 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 23 199 0.0004894 0.005358
426 REGULATION OF MONOCYTE CHEMOTAXIS 6 20 0.0004949 0.005405
427 MITOTIC CELL CYCLE CHECKPOINT 18 139 0.0005077 0.00552
428 REGULATION OF CELL SHAPE 18 139 0.0005077 0.00552
429 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 36 372 0.0005392 0.005848
430 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 24 213 0.0005413 0.005857
431 CELLULAR RESPONSE TO HEAT 8 36 0.0005537 0.005978
432 REGULATION OF MUSCLE CELL DIFFERENTIATION 19 152 0.000562 0.006053
433 CARDIAC VENTRICLE DEVELOPMENT 15 106 0.0005689 0.006113
434 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 7 28 0.0005746 0.006146
435 REGULATION OF SPROUTING ANGIOGENESIS 7 28 0.0005746 0.006146
436 ENDOCHONDRAL BONE MORPHOGENESIS 9 45 0.0005791 0.00618
437 DEVELOPMENTAL GROWTH 33 333 0.0005978 0.006365
438 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 5 14 0.0006071 0.00645
439 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 13 85 0.0006155 0.006523
440 MYELOID LEUKOCYTE DIFFERENTIATION 14 96 0.0006318 0.006666
441 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 14 96 0.0006318 0.006666
442 MICROTUBULE CYTOSKELETON ORGANIZATION 34 348 0.0006415 0.006753
443 REGULATION OF B CELL PROLIFERATION 10 55 0.0006464 0.00679
444 NEGATIVE REGULATION OF ORGAN GROWTH 6 21 0.0006613 0.006931
445 CELL MATRIX ADHESION 16 119 0.0006732 0.00701
446 GLIAL CELL MIGRATION 8 37 0.0006734 0.00701
447 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 8 37 0.0006734 0.00701
448 REGULATION OF CHONDROCYTE DIFFERENTIATION 9 46 0.0006859 0.007123
449 CELLULAR RESPONSE TO OXYGEN LEVELS 18 143 0.0007144 0.007404
450 POSITIVE REGULATION OF DEFENSE RESPONSE 35 364 0.0007179 0.007423
451 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 7 29 0.0007224 0.007437
452 CEREBRAL CORTEX RADIALLY ORIENTED CELL MIGRATION 7 29 0.0007224 0.007437
453 EMBRYONIC ORGAN DEVELOPMENT 38 406 0.0007266 0.007464
454 REGULATION OF BODY FLUID LEVELS 45 506 0.0007401 0.007568
455 REGULATION OF DENDRITE DEVELOPMENT 16 120 0.0007386 0.007568
456 CARDIAC CHAMBER DEVELOPMENT 18 144 0.0007762 0.00792
457 POSITIVE REGULATION OF GLIOGENESIS 9 47 0.0008082 0.008229
458 MESENCHYME MORPHOGENESIS 8 38 0.0008131 0.00826
459 NEURON MIGRATION 15 110 0.000844 0.008556
460 CYTOKINE MEDIATED SIGNALING PATHWAY 41 452 0.0008523 0.008621
461 REGULATION OF B CELL RECEPTOR SIGNALING PATHWAY 5 15 0.0008703 0.008635
462 REGULATION OF HEAT GENERATION 5 15 0.0008703 0.008635
463 NEGATIVE REGULATION OF REGULATED SECRETORY PATHWAY 6 22 0.0008681 0.008635
464 ENDOCARDIAL CUSHION MORPHOGENESIS 6 22 0.0008681 0.008635
465 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 11 67 0.0008663 0.008635
466 REGULATION OF T HELPER 1 TYPE IMMUNE RESPONSE 6 22 0.0008681 0.008635
467 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 14 99 0.0008636 0.008635
468 AORTA MORPHOGENESIS 6 22 0.0008681 0.008635
469 POSITIVE REGULATION OF MONOCYTE CHEMOTAXIS 5 15 0.0008703 0.008635
470 CELLULAR RESPONSE TO INTERFERON GAMMA 16 122 0.0008858 0.008769
471 INTERACTION WITH HOST 17 134 0.0009078 0.008949
472 DNA REPLICATION 23 208 0.0009063 0.008949
473 RENAL TUBULE DEVELOPMENT 12 78 0.0009334 0.009183
474 SEGMENTATION 13 89 0.0009599 0.009423
475 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 59 720 0.0009649 0.009452
476 NEGATIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 8 39 0.0009751 0.009531
477 ADENYLATE CYCLASE INHIBITING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 11 68 0.0009839 0.009577
478 POSITIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 11 68 0.0009839 0.009577
479 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 17 135 0.0009875 0.009593
480 REGULATION OF T CELL PROLIFERATION 18 147 0.0009896 0.009593
481 REGULATION OF RESPONSE TO WOUNDING 38 413 0.0009984 0.009658
482 RESPIRATORY SYSTEM DEVELOPMENT 22 197 0.001018 0.009803
483 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 22 197 0.001018 0.009803
484 APOPTOTIC SIGNALING PATHWAY 29 289 0.001026 0.00986
485 NEGATIVE REGULATION OF CELL ADHESION 24 223 0.001038 0.009962
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE BINDING 85 606 4.676e-16 4.344e-13
2 ENZYME BINDING 159 1737 1.577e-11 7.327e-09
3 RECEPTOR BINDING 134 1476 1.359e-09 4.209e-07
4 CYTOSKELETAL PROTEIN BINDING 80 819 1.964e-07 2.28e-05
5 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 66 629 1.865e-07 2.28e-05
6 PROTEIN COMPLEX BINDING 89 935 1.266e-07 2.28e-05
7 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 42 328 1.91e-07 2.28e-05
8 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 33 226 1.909e-07 2.28e-05
9 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 40 315 4.633e-07 4.304e-05
10 MACROMOLECULAR COMPLEX BINDING 119 1399 4.326e-07 4.304e-05
11 CELL ADHESION MOLECULE BINDING 27 186 2.714e-06 0.0002292
12 RIBONUCLEOTIDE BINDING 145 1860 3.41e-06 0.000264
13 SH3 DOMAIN BINDING 20 116 3.78e-06 0.0002701
14 PROTEIN TYROSINE KINASE BINDING 13 54 4.361e-06 0.0002894
15 CALCIUM ION BINDING 66 697 6.648e-06 0.0004117
16 SIGNALING ADAPTOR ACTIVITY 15 74 8.046e-06 0.0004672
17 ACTIN BINDING 43 393 9.122e-06 0.0004985
18 BINDING BRIDGING 24 173 2.074e-05 0.001043
19 PROTEIN DOMAIN SPECIFIC BINDING 59 624 2.133e-05 0.001043
20 PROTEIN KINASE ACTIVITY 60 640 2.34e-05 0.001087
21 REGULATORY REGION NUCLEIC ACID BINDING 72 818 3.072e-05 0.001359
22 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 97 1199 4.066e-05 0.001717
23 MOLECULAR FUNCTION REGULATOR 106 1353 6.525e-05 0.002636
24 ADENYL NUCLEOTIDE BINDING 116 1514 7.462e-05 0.002888
25 APOLIPOPROTEIN BINDING 6 15 8.069e-05 0.002998
26 GLYCOPROTEIN BINDING 16 101 9.93e-05 0.003548
27 GROWTH FACTOR BINDING 18 123 0.0001082 0.003723
28 METALLOENDOPEPTIDASE ACTIVITY 17 113 0.0001178 0.003908
29 COLLAGEN BINDING 12 65 0.000165 0.004759
30 INTEGRIN BINDING 16 105 0.0001588 0.004759
31 CORECEPTOR ACTIVITY 9 38 0.0001497 0.004759
32 PROTEIN SERINE THREONINE KINASE ACTIVITY 43 445 0.000169 0.004759
33 SEMAPHORIN RECEPTOR ACTIVITY 5 11 0.0001606 0.004759
34 KINASE ACTIVITY 69 842 0.0003705 0.009833
35 CYTOKINE RECEPTOR BINDING 29 271 0.0003636 0.009833
NumGOOverlapSizeP ValueAdj. P Value
1 INTRINSIC COMPONENT OF PLASMA MEMBRANE 159 1649 2.38e-13 1.39e-10
2 MEMBRANE MICRODOMAIN 47 288 1.03e-11 3.008e-09
3 CELL SURFACE 85 757 1.087e-10 2.116e-08
4 CELL JUNCTION 108 1151 1.128e-08 1.647e-06
5 SIDE OF MEMBRANE 53 428 1.542e-08 1.801e-06
6 GOLGI APPARATUS 126 1445 4.773e-08 4.646e-06
7 EXTERNAL SIDE OF PLASMA MEMBRANE 35 238 6.841e-08 5.075e-06
8 PLASMA MEMBRANE PROTEIN COMPLEX 58 510 6.953e-08 5.075e-06
9 MEMBRANE REGION 101 1134 4.342e-07 2.817e-05
10 ANCHORING JUNCTION 54 489 5.048e-07 2.948e-05
11 PLASMA MEMBRANE RAFT 18 86 6.228e-07 3.307e-05
12 RECEPTOR COMPLEX 40 327 1.22e-06 5.937e-05
13 CELL SUBSTRATE JUNCTION 44 398 5.523e-06 0.0002481
14 NEURON PROJECTION 83 942 7.308e-06 0.0003048
15 SOMATODENDRITIC COMPARTMENT 62 650 1.008e-05 0.0003924
16 CELL PROJECTION 137 1786 1.485e-05 0.0005419
17 NEURON PART 103 1265 1.788e-05 0.0006096
18 GOLGI APPARATUS PART 78 893 1.879e-05 0.0006096
19 EXCITATORY SYNAPSE 25 197 6.407e-05 0.001871
20 CELL BODY 48 494 6.322e-05 0.001871
21 SYNAPSE 66 754 7.723e-05 0.002148
22 SEMAPHORIN RECEPTOR COMPLEX 5 11 0.0001606 0.004262
23 POSTSYNAPSE 38 378 0.0001795 0.004558
24 PLASMA MEMBRANE REGION 76 929 0.0001993 0.004661
25 ENDOPLASMIC RETICULUM 121 1631 0.0001995 0.004661
26 ACTIN CYTOSKELETON 42 444 0.0003146 0.007067
27 DENDRITE 42 451 0.0004354 0.009417

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 PI3K_Akt_signaling_pathway_hsa04151 46 352 2.7e-08 1.404e-06
2 Cytokine_cytokine_receptor_interaction_hsa04060 35 270 1.478e-06 3.843e-05
3 HIF_1_signaling_pathway_hsa04066 18 100 6.113e-06 0.000106
4 Rap1_signaling_pathway_hsa04015 27 206 1.857e-05 0.0002415
5 MAPK_signaling_pathway_hsa04010 34 295 2.669e-05 0.0002747
6 Cell_adhesion_molecules_.CAMs._hsa04514 21 145 3.503e-05 0.0002747
7 Cell_cycle_hsa04110 19 124 3.698e-05 0.0002747
8 Ras_signaling_pathway_hsa04014 28 232 5.94e-05 0.0003861
9 Focal_adhesion_hsa04510 24 199 0.0001968 0.001137
10 FoxO_signaling_pathway_hsa04068 18 132 0.000268 0.001394
11 ErbB_signaling_pathway_hsa04012 13 85 0.0006155 0.002909
12 Notch_signaling_pathway_hsa04330 9 48 0.0009477 0.003935
13 p53_signaling_pathway_hsa04115 11 68 0.0009839 0.003935
14 ECM_receptor_interaction_hsa04512 12 82 0.001461 0.005427
15 NF_kappa_B_signaling_pathway_hsa04064 13 95 0.001769 0.006131
16 Phospholipase_D_signaling_pathway_hsa04072 17 146 0.002333 0.007584
17 cGMP_PKG_signaling_pathway_hsa04022 17 163 0.007184 0.02197
18 Cellular_senescence_hsa04218 16 160 0.01306 0.03773
19 Hippo_signaling_pathway_multiple_species_hsa04392 5 29 0.01838 0.05032
20 Gap_junction_hsa04540 10 88 0.02021 0.05254
21 Jak_STAT_signaling_pathway_hsa04630 15 162 0.02954 0.07314
22 TNF_signaling_pathway_hsa04668 11 108 0.0317 0.07492
23 Regulation_of_actin_cytoskeleton_hsa04810 18 208 0.03336 0.07542
24 Phagosome_hsa04145 14 152 0.03603 0.07807
25 cAMP_signaling_pathway_hsa04024 17 198 0.04032 0.08387
26 Hippo_signaling_pathway_hsa04390 13 154 0.07417 0.1483
27 TGF_beta_signaling_pathway_hsa04350 8 84 0.08373 0.1613
28 Adherens_junction_hsa04520 7 72 0.0935 0.1687
29 ABC_transporters_hsa02010 5 45 0.09408 0.1687
30 Apoptosis_multiple_species_hsa04215 4 33 0.1005 0.1741
31 Sphingolipid_signaling_pathway_hsa04071 10 118 0.1058 0.1774
32 Ferroptosis_hsa04216 4 40 0.1684 0.2737
33 Apelin_signaling_pathway_hsa04371 10 137 0.2071 0.3207
34 Tight_junction_hsa04530 12 170 0.2097 0.3207
35 Oocyte_meiosis_hsa04114 9 124 0.2279 0.3386
36 Hedgehog_signaling_pathway_hsa04340 4 47 0.2481 0.3584
37 Wnt_signaling_pathway_hsa04310 10 146 0.2656 0.3733
38 Lysosome_hsa04142 8 123 0.3473 0.4753
39 Calcium_signaling_pathway_hsa04020 11 182 0.3959 0.5151
40 VEGF_signaling_pathway_hsa04370 4 59 0.3962 0.5151
41 Neuroactive_ligand_receptor_interaction_hsa04080 16 278 0.4346 0.5512
42 AMPK_signaling_pathway_hsa04152 7 121 0.4824 0.5972
43 Autophagy_other_hsa04136 2 32 0.5223 0.6264
44 Necroptosis_hsa04217 9 164 0.53 0.6264
45 Apoptosis_hsa04210 7 138 0.6225 0.707
46 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.6254 0.707
47 Endocytosis_hsa04144 12 244 0.673 0.7446
48 Autophagy_animal_hsa04140 6 128 0.6965 0.7546
49 mTOR_signaling_pathway_hsa04150 6 151 0.8316 0.8826
50 Mitophagy_animal_hsa04137 2 65 0.8731 0.8939
51 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 5 139 0.8767 0.8939
52 Peroxisome_hsa04146 2 83 0.9433 0.9433

Quest ID: 15196c7e76db10ff7a65ed80af3521c2