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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-93-5p ABHD2 -0.38 0.73231 0.1 0.86123 miRNATAP -0.11 0.00864 NA
2 hsa-miR-93-5p ACSL4 -0.38 0.73231 0.17 0.75895 MirTarget; miRNATAP -0.14 0.00238 NA
3 hsa-miR-93-5p ADCY9 -0.38 0.73231 0.13 0.77747 mirMAP -0.15 0.0046 NA
4 hsa-miR-93-5p AHNAK -0.38 0.73231 0.11 0.89617 miRNATAP -0.22 0.00021 NA
5 hsa-miR-93-5p AKAP11 -0.38 0.73231 0.07 0.87746 miRNAWalker2 validate -0.12 0.00019 NA
6 hsa-miR-93-5p AKT3 -0.38 0.73231 0.09 0.82989 miRNATAP -0.27 0.00266 NA
7 hsa-miR-93-5p AKTIP -0.38 0.73231 0.21 0.58008 MirTarget; miRNATAP -0.16 0 NA
8 hsa-miR-93-5p ANXA11 -0.38 0.73231 0.24 0.7496 mirMAP -0.12 0.00457 NA
9 hsa-miR-93-5p APCDD1 -0.38 0.73231 0.16 0.76904 MirTarget -0.24 0.00108 NA
10 hsa-miR-93-5p APLP2 -0.38 0.73231 0.16 0.85038 miRNAWalker2 validate -0.13 0.0024 NA
11 hsa-miR-93-5p ARHGAP23 -0.38 0.73231 -0.19 0.77018 mirMAP -0.21 0.00064 NA
12 hsa-miR-93-5p ARL13B -0.38 0.73231 0.08 0.85668 MirTarget -0.12 0.01427 NA
13 hsa-miR-93-5p ARSJ -0.38 0.73231 0.63 0.12113 miRNAWalker2 validate -0.2 0.04212 NA
14 hsa-miR-93-5p BAMBI -0.38 0.73231 0.04 0.93137 MirTarget; miRNATAP -0.49 1.0E-5 NA
15 hsa-miR-93-5p BCL2L2 -0.38 0.73231 -0.24 0.61373 miRNATAP -0.11 0.0084 NA
16 hsa-miR-93-5p BNC2 -0.38 0.73231 0.55 0.26554 miRNATAP -0.18 0.0223 NA
17 hsa-miR-93-5p BNIP3L -0.38 0.73231 0.05 0.92792 MirTarget -0.13 0.00068 NA
18 hsa-miR-93-5p C14orf28 -0.38 0.73231 -0.05 0.86024 miRNATAP -0.16 7.0E-5 NA
19 hsa-miR-93-5p CALD1 -0.38 0.73231 0.41 0.56714 miRNATAP -0.14 0.01107 NA
20 hsa-miR-93-5p CAMK2N1 -0.38 0.73231 0 0.99952 miRNATAP -0.34 0.00052 NA
21 hsa-miR-93-5p CASC4 -0.38 0.73231 0.44 0.47072 MirTarget -0.16 1.0E-5 NA
22 hsa-miR-93-5p CAV2 -0.38 0.73231 -0.1 0.83287 miRNAWalker2 validate -0.2 0.00145 NA
23 hsa-miR-93-5p CBX7 -0.38 0.73231 0.05 0.91939 mirMAP -0.19 0.00049 NA
24 hsa-miR-93-5p CCND1 -0.38 0.73231 -0.04 0.9587 miRNAWalker2 validate; MirTarget; miRNATAP -0.31 0.00214 NA
25 hsa-miR-93-5p CDC37L1 -0.38 0.73231 0.07 0.85295 miRNAWalker2 validate; MirTarget; miRNATAP -0.1 0.0222 NA
26 hsa-miR-93-5p CERK -0.38 0.73231 0.17 0.75314 mirMAP -0.2 2.0E-5 NA
27 hsa-miR-93-5p CHD9 -0.38 0.73231 0.05 0.91737 MirTarget; miRNATAP -0.14 0.00017 NA
28 hsa-miR-93-5p CLDN16 -0.38 0.73231 0.46 0.56414 mirMAP -0.4 0.03967 NA
29 hsa-miR-93-5p CLUAP1 -0.38 0.73231 -0 0.99355 mirMAP -0.13 0.00162 NA
30 hsa-miR-93-5p CNTNAP3 -0.38 0.73231 0.78 0.1641 MirTarget -0.5 0.00079 NA
31 hsa-miR-93-5p COL1A1 -0.38 0.73231 0.66 0.55215 mirMAP -0.24 0.03626 NA
32 hsa-miR-93-5p CPPED1 -0.38 0.73231 0.14 0.76095 miRNAWalker2 validate -0.1 0.02742 NA
33 hsa-miR-93-5p CRELD2 -0.38 0.73231 0.07 0.85452 miRNAWalker2 validate -0.16 0.00093 NA
34 hsa-miR-93-5p CRIM1 -0.38 0.73231 0.2 0.72582 MirTarget; miRNATAP -0.14 0.00211 NA
35 hsa-miR-93-5p CRY2 -0.38 0.73231 -0.07 0.88176 miRNAWalker2 validate; MirTarget; miRNATAP -0.12 0.00036 NA
36 hsa-miR-93-5p CTDSPL -0.38 0.73231 -0.03 0.95226 mirMAP -0.11 0.00681 NA
37 hsa-miR-93-5p CTSK -0.38 0.73231 0.84 0.17913 MirTarget -0.26 0.03 NA
38 hsa-miR-93-5p CYBRD1 -0.38 0.73231 0.45 0.50235 MirTarget -0.21 0.00133 NA
39 hsa-miR-93-5p CYP2U1 -0.38 0.73231 0.22 0.55336 MirTarget -0.13 0.00488 NA
40 hsa-miR-93-5p DCTN6 -0.38 0.73231 0.4 0.36112 miRNAWalker2 validate -0.17 1.0E-5 NA
41 hsa-miR-93-5p DPYD -0.38 0.73231 0.09 0.83537 MirTarget -0.22 0.00899 NA
42 hsa-miR-93-5p DPYSL2 -0.38 0.73231 0.47 0.41291 MirTarget; miRNATAP -0.23 5.0E-5 NA
43 hsa-miR-93-5p EAPP -0.38 0.73231 0.14 0.76823 miRNAWalker2 validate -0.14 7.0E-5 NA
44 hsa-miR-93-5p EDA2R -0.38 0.73231 0.37 0.17818 MirTarget -0.19 0.00903 NA
45 hsa-miR-93-5p EGLN3 -0.38 0.73231 -0.08 0.87805 miRNAWalker2 validate -0.32 0.00096 NA
46 hsa-miR-93-5p ELK3 -0.38 0.73231 0.32 0.4199 MirTarget; miRNATAP -0.14 0.00257 NA
47 hsa-miR-93-5p EPHA4 -0.38 0.73231 -0.13 0.79518 miRNAWalker2 validate; miRNATAP -0.22 0.01772 NA
48 hsa-miR-93-5p ETV1 -0.38 0.73231 0.55 0.19095 MirTarget; miRNATAP -0.4 0 NA
49 hsa-miR-93-5p F3 -0.38 0.73231 -0.04 0.93088 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0.02735 NA
50 hsa-miR-93-5p FAM189A1 -0.38 0.73231 0.48 0.3222 MirTarget; miRNATAP -0.4 0.00181 NA
51 hsa-miR-93-5p FAM84B -0.38 0.73231 0.12 0.84199 mirMAP; miRNATAP -0.18 0.00132 NA
52 hsa-miR-93-5p FAT3 -0.38 0.73231 0.76 0.17189 mirMAP -0.34 0.0232 NA
53 hsa-miR-93-5p FAT4 -0.38 0.73231 0.15 0.6548 MirTarget; miRNATAP -0.17 0.01345 NA
54 hsa-miR-93-5p FBXL3 -0.38 0.73231 0.05 0.92348 miRNAWalker2 validate -0.19 0 NA
55 hsa-miR-93-5p FBXL5 -0.38 0.73231 0.15 0.8001 miRNAWalker2 validate; miRNATAP -0.11 0.00208 NA
56 hsa-miR-93-5p FGFR1 -0.38 0.73231 0.3 0.66065 mirMAP -0.22 0.00194 NA
57 hsa-miR-93-5p FHL2 -0.38 0.73231 0.09 0.87754 mirMAP -0.16 0.01842 NA
58 hsa-miR-93-5p FIBIN -0.38 0.73231 0.04 0.93498 MirTarget -0.31 0.00157 NA
59 hsa-miR-93-5p FKBP7 -0.38 0.73231 0.21 0.57948 miRNAWalker2 validate -0.19 0.00028 NA
60 hsa-miR-93-5p FOXQ1 -0.38 0.73231 -0.56 0.37822 MirTarget -0.38 0.00143 NA
61 hsa-miR-93-5p FRMD6 -0.38 0.73231 0.17 0.68256 MirTarget; miRNATAP -0.15 0.02525 NA
62 hsa-miR-93-5p FTO -0.38 0.73231 0.11 0.82 mirMAP -0.12 6.0E-5 NA
63 hsa-miR-93-5p FYCO1 -0.38 0.73231 -0.07 0.89797 miRNAWalker2 validate; MirTarget -0.11 0.00451 NA
64 hsa-miR-93-5p GABBR2 -0.38 0.73231 0.99 0.12191 miRNATAP -0.48 0.00508 NA
65 hsa-miR-93-5p GAS7 -0.38 0.73231 0.42 0.40611 mirMAP -0.17 0.00761 NA
66 hsa-miR-93-5p GLIS3 -0.38 0.73231 0.51 0.2891 miRNATAP -0.22 0.00974 NA
67 hsa-miR-93-5p GNAQ -0.38 0.73231 0.11 0.84297 mirMAP -0.16 3.0E-5 NA
68 hsa-miR-93-5p GNE -0.38 0.73231 -0.24 0.53753 mirMAP -0.13 0.02484 NA
69 hsa-miR-93-5p GPR12 -0.38 0.73231 0.56 0.52224 mirMAP -0.83 0.00044 NA
70 hsa-miR-93-5p GPRC5A -0.38 0.73231 -0.25 0.68655 mirMAP -0.28 0.00993 NA
71 hsa-miR-93-5p GTDC1 -0.38 0.73231 -0.04 0.92369 MirTarget -0.12 0.00412 NA
72 hsa-miR-93-5p H1F0 -0.38 0.73231 0.03 0.9629 miRNAWalker2 validate -0.14 0.0098 NA
73 hsa-miR-93-5p HABP4 -0.38 0.73231 0.09 0.78487 MirTarget; miRNATAP -0.11 0.00491 NA
74 hsa-miR-93-5p HERPUD1 -0.38 0.73231 0.04 0.95257 miRNAWalker2 validate -0.17 1.0E-5 NA
75 hsa-miR-93-5p HLF -0.38 0.73231 -0.41 0.26253 MirTarget; miRNATAP -0.33 0.00047 NA
76 hsa-miR-93-5p IL17RA -0.38 0.73231 -0.22 0.59195 mirMAP -0.12 0.00648 NA
77 hsa-miR-93-5p IL1RAP -0.38 0.73231 0.32 0.56867 MirTarget -0.13 0.04658 NA
78 hsa-miR-93-5p IMPAD1 -0.38 0.73231 0.05 0.93265 mirMAP -0.11 0.00033 NA
79 hsa-miR-93-5p ISM1 -0.38 0.73231 0.77 0.10359 miRNATAP -0.26 0.01695 NA
80 hsa-miR-93-5p ITPRIPL2 -0.38 0.73231 -0.15 0.78217 MirTarget; miRNATAP -0.15 0.00016 NA
81 hsa-miR-93-5p JRKL -0.38 0.73231 0.27 0.5062 MirTarget -0.13 0.00241 NA
82 hsa-miR-93-5p KAT2B -0.38 0.73231 0.15 0.73166 miRNAWalker2 validate; miRTarBase; MirTarget -0.12 0.01698 NA
83 hsa-miR-93-5p KCND3 -0.38 0.73231 -0.46 0.37684 mirMAP -0.37 0.00654 NA
84 hsa-miR-93-5p KCNMA1 -0.38 0.73231 0.29 0.58227 miRNATAP -0.2 0.02027 NA
85 hsa-miR-93-5p KIAA0513 -0.38 0.73231 -0.2 0.54943 MirTarget; miRNATAP -0.18 0.00588 NA
86 hsa-miR-93-5p KIF26B -0.38 0.73231 0.97 0.06191 miRNATAP -0.3 0.00706 NA
87 hsa-miR-93-5p KLF9 -0.38 0.73231 0.36 0.44184 miRNAWalker2 validate; MirTarget; miRNATAP -0.13 0.01343 NA
88 hsa-miR-93-5p LAPTM4A -0.38 0.73231 0.31 0.68898 MirTarget; miRNATAP -0.1 0.00188 NA
89 hsa-miR-93-5p LAPTM4B -0.38 0.73231 0.49 0.56736 miRNAWalker2 validate -0.13 0.01834 NA
90 hsa-miR-93-5p LATS2 -0.38 0.73231 0.12 0.7784 miRNAWalker2 validate -0.12 0.00846 NA
91 hsa-miR-93-5p LDOC1L -0.38 0.73231 0.07 0.88422 mirMAP -0.11 0.00233 NA
92 hsa-miR-93-5p LIX1L -0.38 0.73231 0.17 0.69603 miRNAWalker2 validate -0.19 5.0E-5 NA
93 hsa-miR-93-5p LOXL1 -0.38 0.73231 0.46 0.4183 miRNAWalker2 validate -0.23 0.00105 NA
94 hsa-miR-93-5p LRP3 -0.38 0.73231 -0.21 0.71786 miRNAWalker2 validate -0.14 0.02146 NA
95 hsa-miR-93-5p LRRN4CL -0.38 0.73231 0.52 0.14165 mirMAP -0.39 1.0E-5 NA
96 hsa-miR-93-5p LYST -0.38 0.73231 -0.18 0.60507 miRNAWalker2 validate -0.11 0.02147 NA
97 hsa-miR-93-5p MAP3K5 -0.38 0.73231 -0.06 0.88239 miRNATAP -0.11 0.03823 NA
98 hsa-miR-93-5p MAPK4 -0.38 0.73231 0.4 0.48173 MirTarget; miRNATAP -0.3 0.04567 NA
99 hsa-miR-93-5p MAPK9 -0.38 0.73231 0.08 0.87211 miRNAWalker2 validate; miRNATAP -0.1 0.00804 NA
100 hsa-miR-93-5p MAPRE3 -0.38 0.73231 0.31 0.44216 miRNAWalker2 validate; MirTarget; miRNATAP -0.2 0.00048 NA
101 hsa-miR-93-5p MBOAT2 -0.38 0.73231 0.5 0.24497 mirMAP -0.18 0.00096 NA
102 hsa-miR-93-5p MCC -0.38 0.73231 -0.01 0.9823 MirTarget -0.14 0.04575 NA
103 hsa-miR-93-5p MCF2L -0.38 0.73231 -0.28 0.52803 mirMAP -0.29 0.00046 NA
104 hsa-miR-93-5p MPG -0.38 0.73231 0.19 0.69823 miRNAWalker2 validate -0.1 0.0176 NA
105 hsa-miR-93-5p MSRB3 -0.38 0.73231 0.65 0.13405 mirMAP -0.27 0.0001 NA
106 hsa-miR-93-5p NBEA -0.38 0.73231 -0.28 0.48636 MirTarget; miRNATAP -0.36 0.00039 NA
107 hsa-miR-93-5p NBL1 -0.38 0.73231 0.77 0.25044 miRNATAP -0.31 9.0E-5 NA
108 hsa-miR-93-5p NEDD9 -0.38 0.73231 0.45 0.42244 mirMAP -0.23 0.00509 NA
109 hsa-miR-93-5p NPAS2 -0.38 0.73231 0.34 0.55313 miRNATAP -0.27 0.00303 NA
110 hsa-miR-93-5p NPM1 -0.38 0.73231 0.34 0.63293 miRNAWalker2 validate -0.14 0.00174 NA
111 hsa-miR-93-5p NPTXR -0.38 0.73231 0.14 0.79951 mirMAP -0.29 0.00037 NA
112 hsa-miR-93-5p NTN4 -0.38 0.73231 0.13 0.82096 MirTarget; miRNATAP -0.18 0.0393 NA
113 hsa-miR-93-5p NTRK3 -0.38 0.73231 0.08 0.90043 mirMAP -0.37 0.0383 NA
114 hsa-miR-93-5p OSBPL5 -0.38 0.73231 -0.07 0.87225 miRNATAP -0.12 0.01001 NA
115 hsa-miR-93-5p PBXIP1 -0.38 0.73231 0.07 0.90648 miRNAWalker2 validate -0.17 5.0E-5 NA
116 hsa-miR-93-5p PCDHA12 -0.38 0.73231 0.43 0.53413 MirTarget -0.38 0.03905 NA
117 hsa-miR-93-5p PCYT1B -0.38 0.73231 0.43 0.28972 miRNATAP -0.28 0.01044 NA
118 hsa-miR-93-5p PDGFRA -0.38 0.73231 0.51 0.39347 MirTarget; miRNATAP -0.32 0.00269 NA
119 hsa-miR-93-5p PGM2L1 -0.38 0.73231 -0.09 0.85474 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.04008 NA
120 hsa-miR-93-5p PKD2 -0.38 0.73231 0.08 0.84775 miRNAWalker2 validate; MirTarget; miRNATAP -0.14 0.00087 NA
121 hsa-miR-93-5p PLAG1 -0.38 0.73231 0.21 0.6907 miRNATAP -0.23 0.02754 NA
122 hsa-miR-93-5p PLSCR4 -0.38 0.73231 0.43 0.37049 MirTarget -0.25 0.00037 NA
123 hsa-miR-93-5p PPARA -0.38 0.73231 -0.02 0.97331 miRNATAP -0.11 0.01431 NA
124 hsa-miR-93-5p PPP3CA -0.38 0.73231 0.26 0.60892 miRNATAP -0.14 0.00165 NA
125 hsa-miR-93-5p PRELP -0.38 0.73231 0.87 0.16321 mirMAP -0.46 3.0E-5 NA
126 hsa-miR-93-5p PRR16 -0.38 0.73231 0.67 0.07927 MirTarget; miRNATAP -0.25 0.01269 NA
127 hsa-miR-93-5p PRRG1 -0.38 0.73231 0.57 0.16845 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.01874 NA
128 hsa-miR-93-5p PTEN -0.38 0.73231 0.16 0.78173 miRNAWalker2 validate; miRTarBase; miRNATAP -0.15 0.00249 22465665; 26087719; 25633810; 26243299 Furthermore we found that miR-93 can directly target PTEN and participates in the regulation of the AKT signaling pathway; MiR-93 inversely correlates with PTEN expression in CDDP-resistant and sensitive human ovarian cancer tissues;Furthermore our study found berberine could inhibit miR-93 expression and function in ovarian cancer as shown by an increase of its target PTEN an important tumor suppressor in ovarian cancer; More importantly A2780 cells that were treated with PTEN siRNA had a survival pattern that is similar to cells with miR-93 overexpression;MicroRNA 93 activates c Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A; We confirmed that miR-93 directly bound with the 3' untranslated regions of the tumor-suppressor genes PTEN and CDKN1A respectivelyand inhibited their expression; We concluded that miR-93 stimulated cell proliferation migration and invasion through the oncogenic c-Met/PI3K/Akt pathway and also inhibited apoptosis by directly inhibiting PTEN and CDKN1A expression in human HCC;microRNA 93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells; An miRNA miR-93 was significantly up-regulated whereas phosphatase and tensin homologue PTEN expression was significantly down-regulated in all tested OS cells when compared with hMSCs; Ectopic expression of miR-93 decreased PTEN protein levels; Taking these observations together miR-93 can be seen to play a critical role in carcinogenesis through suppression of PTEN and may serve as a therapeutic target for the treatment of OS
129 hsa-miR-93-5p PTGER3 -0.38 0.73231 1.5 0.0075 miRNATAP -0.4 0.00485 NA
130 hsa-miR-93-5p PTHLH -0.38 0.73231 0.4 0.23906 MirTarget -0.25 0.00589 NA
131 hsa-miR-93-5p PTRF -0.38 0.73231 0.56 0.40604 mirMAP -0.23 0.00028 NA
132 hsa-miR-93-5p PURA -0.38 0.73231 0.08 0.85573 miRNAWalker2 validate; miRTarBase; MirTarget -0.17 0 NA
133 hsa-miR-93-5p RAB11FIP1 -0.38 0.73231 -0.14 0.80137 miRNAWalker2 validate; MirTarget -0.14 0.01266 NA
134 hsa-miR-93-5p RAB11FIP5 -0.38 0.73231 -0.14 0.76319 MirTarget -0.13 0.00195 NA
135 hsa-miR-93-5p RAB30 -0.38 0.73231 -0.01 0.97099 mirMAP; miRNATAP -0.14 0.01594 NA
136 hsa-miR-93-5p RASGRF2 -0.38 0.73231 0.27 0.45019 MirTarget -0.22 0.01285 NA
137 hsa-miR-93-5p RB1 -0.38 0.73231 0.27 0.62155 miRNAWalker2 validate; MirTarget; miRNATAP -0.12 0.02714 NA
138 hsa-miR-93-5p RBM43 -0.38 0.73231 0.07 0.84698 mirMAP -0.12 0.00534 NA
139 hsa-miR-93-5p RGL1 -0.38 0.73231 -0.06 0.90775 MirTarget; miRNATAP -0.12 0.0179 NA
140 hsa-miR-93-5p RGMA -0.38 0.73231 -0.09 0.86627 miRNATAP -0.21 0.0061 NA
141 hsa-miR-93-5p RNASEL -0.38 0.73231 0.15 0.64442 MirTarget -0.15 0.00062 NA
142 hsa-miR-93-5p RND3 -0.38 0.73231 -0.18 0.73894 miRNAWalker2 validate -0.18 0.00298 NA
143 hsa-miR-93-5p RORA -0.38 0.73231 -0.11 0.76005 MirTarget; miRNATAP -0.16 0.00576 NA
144 hsa-miR-93-5p RPL27 -0.38 0.73231 0.45 0.60158 miRNAWalker2 validate -0.2 0.00044 NA
145 hsa-miR-93-5p RPL30 -0.38 0.73231 0.53 0.55367 miRNAWalker2 validate -0.17 0.0009 NA
146 hsa-miR-93-5p RPL7A -0.38 0.73231 0.33 0.65164 miRNAWalker2 validate -0.13 0.00468 NA
147 hsa-miR-93-5p RPL9 -0.38 0.73231 0.12 0.77872 miRNAWalker2 validate -0.16 0.01298 NA
148 hsa-miR-93-5p RUNX1 -0.38 0.73231 0.45 0.46374 miRNATAP -0.23 0.00139 NA
149 hsa-miR-93-5p SCAMP2 -0.38 0.73231 0.21 0.74683 MirTarget -0.1 0.00354 NA
150 hsa-miR-93-5p SCN2B -0.38 0.73231 1.21 0.00973 MirTarget -0.29 0.01757 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF CELL DIFFERENTIATION 37 1492 2.632e-07 0.0009366
2 TISSUE DEVELOPMENT 37 1518 4.026e-07 0.0009366
3 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 40 1784 1.074e-06 0.001666
4 RHYTHMIC PROCESS 14 298 2.055e-06 0.00239
5 MUSCLE TISSUE DEVELOPMENT 13 275 4.487e-06 0.002661
6 HEART DEVELOPMENT 17 466 5.147e-06 0.002661
7 CARDIOVASCULAR SYSTEM DEVELOPMENT 23 788 4.699e-06 0.002661
8 REGULATION OF PHOSPHORUS METABOLIC PROCESS 36 1618 4.906e-06 0.002661
9 CIRCULATORY SYSTEM DEVELOPMENT 23 788 4.699e-06 0.002661
10 RESPONSE TO ENDOGENOUS STIMULUS 33 1450 8.147e-06 0.003791
11 REGULATION OF CIRCADIAN RHYTHM 8 103 9.515e-06 0.004025
12 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 38 1848 1.574e-05 0.005635
13 CELL DEVELOPMENT 32 1426 1.513e-05 0.005635
14 NEGATIVE REGULATION OF CELL COMMUNICATION 28 1192 2.455e-05 0.00816
15 MUSCLE STRUCTURE DEVELOPMENT 15 432 3.326e-05 0.009603
16 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 17 541 3.508e-05 0.009603
17 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 17 541 3.508e-05 0.009603
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE BINDING 20 606 3.37e-06 0.003131
NumGOOverlapSizeP ValueAdj. P Value

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04710_Circadian_rhythm_._mammal 4 23 7.548e-05 0.01359
2 hsa04380_Osteoclast_differentiation 7 128 0.0003162 0.02846
3 hsa04510_Focal_adhesion 8 200 0.0009646 0.05788
4 hsa04390_Hippo_signaling_pathway 6 154 0.004698 0.1756
5 hsa04920_Adipocytokine_signaling_pathway 4 68 0.004884 0.1756
6 hsa04010_MAPK_signaling_pathway 8 268 0.005853 0.1756
7 hsa03010_Ribosome 4 92 0.01392 0.358
8 hsa04144_Endocytosis 6 203 0.01692 0.3808
9 hsa04141_Protein_processing_in_endoplasmic_reticulum 5 168 0.02755 0.4628
10 hsa04270_Vascular_smooth_muscle_contraction 4 116 0.02968 0.4628
11 hsa04115_p53_signaling_pathway 3 69 0.03229 0.4628
12 hsa04014_Ras_signaling_pathway 6 236 0.03233 0.4628
13 hsa04020_Calcium_signaling_pathway 5 177 0.03342 0.4628
14 hsa04722_Neurotrophin_signaling_pathway 4 127 0.0394 0.5066
15 hsa04360_Axon_guidance 4 130 0.04233 0.508
16 hsa04350_TGF.beta_signaling_pathway 3 85 0.05426 0.518
17 hsa04914_Progesterone.mediated_oocyte_maturation 3 87 0.0574 0.518
18 hsa04210_Apoptosis 3 89 0.06063 0.518
19 hsa04970_Salivary_secretion 3 89 0.06063 0.518
20 hsa00600_Sphingolipid_metabolism 2 40 0.06111 0.518
21 hsa04540_Gap_junction 3 90 0.06227 0.518
22 hsa04151_PI3K_AKT_signaling_pathway 7 351 0.06474 0.518
23 hsa04310_Wnt_signaling_pathway 4 151 0.06619 0.518
24 hsa04630_Jak.STAT_signaling_pathway 4 155 0.07138 0.52
25 hsa04962_Vasopressin.regulated_water_reabsorption 2 44 0.07223 0.52
26 hsa04912_GnRH_signaling_pathway 3 101 0.08169 0.5372
27 hsa04972_Pancreatic_secretion 3 101 0.08169 0.5372
28 hsa04620_Toll.like_receptor_signaling_pathway 3 102 0.08357 0.5372
29 hsa04660_T_cell_receptor_signaling_pathway 3 108 0.09524 0.5911
30 hsa04142_Lysosome 3 121 0.1226 0.7357
31 hsa04530_Tight_junction 3 133 0.1501 0.7604
32 hsa03320_PPAR_signaling_pathway 2 70 0.1563 0.7604
33 hsa04720_Long.term_potentiation 2 70 0.1563 0.7604
34 hsa04520_Adherens_junction 2 73 0.1669 0.78
35 hsa04971_Gastric_acid_secretion 2 74 0.1705 0.78
36 hsa04662_B_cell_receptor_signaling_pathway 2 75 0.1741 0.78
37 hsa04370_VEGF_signaling_pathway 2 76 0.1777 0.78
38 hsa04664_Fc_epsilon_RI_signaling_pathway 2 79 0.1885 0.8043
39 hsa00564_Glycerophospholipid_metabolism 2 80 0.1921 0.8043
40 hsa04512_ECM.receptor_interaction 2 85 0.2104 0.8417
41 hsa04012_ErbB_signaling_pathway 2 87 0.2178 0.8523
42 hsa04916_Melanogenesis 2 101 0.2698 1
43 hsa04114_Oocyte_meiosis 2 114 0.3181 1
44 hsa04110_Cell_cycle 2 128 0.3692 1
45 hsa04910_Insulin_signaling_pathway 2 138 0.4048 1
46 hsa04062_Chemokine_signaling_pathway 2 189 0.5686 1
47 hsa04810_Regulation_of_actin_cytoskeleton 2 214 0.6362 1

Quest ID: 19630579325555717618f07480dfc3ce