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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-194-5p ADAMTS5 2.24 0 0.19 0.27716 mirMAP -0.1 0.00032 NA
2 hsa-miR-194-5p ALDH1L2 2.24 0 0.23 0.32096 mirMAP -0.14 0.00018 NA
3 hsa-miR-194-5p ANGPTL1 2.24 0 -2.71 0 MirTarget -0.77 0 NA
4 hsa-miR-194-5p ARHGAP24 2.24 0 -0.93 0 miRNATAP -0.16 0 NA
5 hsa-miR-194-5p ASAP1 2.24 0 0.66 0 MirTarget; miRNATAP -0.1 0 NA
6 hsa-miR-194-5p BICD2 2.24 0 -0.02 0.88611 miRNATAP -0.22 0 NA
7 hsa-miR-194-5p BNC1 2.24 0 -1.62 0.00071 MirTarget -0.53 0 NA
8 hsa-miR-194-5p BNIP2 2.24 0 -0.05 0.63907 MirTarget -0.15 0 NA
9 hsa-miR-194-5p BRMS1L 2.24 0 -0.02 0.82317 MirTarget -0.11 0 NA
10 hsa-miR-194-5p C1orf21 2.24 0 -0.73 9.0E-5 mirMAP; miRNATAP -0.11 0.00076 NA
11 hsa-miR-194-5p CADM1 2.24 0 -0.9 0.00084 miRNATAP -0.28 0 NA
12 hsa-miR-194-5p CAMK2G 2.24 0 -0.53 0.00041 miRNATAP -0.15 0 NA
13 hsa-miR-194-5p CBX5 2.24 0 0.16 0.24446 mirMAP -0.13 0 NA
14 hsa-miR-194-5p CDH2 2.24 0 -0.68 0.04042 miRNAWalker2 validate; miRTarBase; miRNATAP -0.38 0 21845495; 20979124 The results of real-time PCR and western blot highlighted that miR-194 interacted with N-cadherin and negatively regulated its expression at the translational level;The overexpression of miR-194 in liver mesenchymal-like cancer cells reduced the expression of the mesenchymal cell marker N-cadherin and suppressed invasion and migration of the mesenchymal-like cancer cells both in vitro and in vivo
15 hsa-miR-194-5p CDK14 2.24 0 -0.3 0.18672 MirTarget -0.26 0 NA
16 hsa-miR-194-5p CDK5R2 2.24 0 -1.28 0.01166 mirMAP -0.19 0.02733 NA
17 hsa-miR-194-5p CEP170 2.24 0 0.94 0 miRNATAP -0.11 4.0E-5 NA
18 hsa-miR-194-5p CHD5 2.24 0 -0.92 0.01521 mirMAP -0.4 0 NA
19 hsa-miR-194-5p CHRNB2 2.24 0 -0.9 0.01463 mirMAP -0.18 0.00381 NA
20 hsa-miR-194-5p CLASP1 2.24 0 0.09 0.35045 miRNATAP -0.14 0 NA
21 hsa-miR-194-5p CLIP4 2.24 0 -1.15 1.0E-5 MirTarget -0.44 0 NA
22 hsa-miR-194-5p CLLU1 2.24 0 -1.13 0.00877 miRNATAP -0.18 0.01381 NA
23 hsa-miR-194-5p DAAM1 2.24 0 -0.34 0.0105 miRNATAP -0.22 0 NA
24 hsa-miR-194-5p DCBLD2 2.24 0 -0.14 0.5524 MirTarget -0.29 0 NA
25 hsa-miR-194-5p DCUN1D4 2.24 0 -0.26 0.02159 MirTarget -0.11 0 NA
26 hsa-miR-194-5p DIP2C 2.24 0 -0.44 0.01713 miRNATAP -0.22 0 NA
27 hsa-miR-194-5p DMD 2.24 0 -1.51 0 MirTarget; miRNATAP -0.42 0 NA
28 hsa-miR-194-5p DUSP10 2.24 0 0.51 0.00228 miRNATAP -0.11 8.0E-5 NA
29 hsa-miR-194-5p EGR2 2.24 0 0.31 0.17079 miRNATAP -0.12 0.00109 NA
30 hsa-miR-194-5p EHBP1 2.24 0 -0.08 0.56084 MirTarget; miRNATAP -0.2 0 NA
31 hsa-miR-194-5p EIF4E3 2.24 0 -1.24 0 miRNATAP -0.19 0 NA
32 hsa-miR-194-5p EMCN 2.24 0 -0.47 0.01631 MirTarget -0.18 0 NA
33 hsa-miR-194-5p ENAH 2.24 0 -0.3 0.08986 mirMAP; miRNATAP -0.15 0 NA
34 hsa-miR-194-5p EPHA3 2.24 0 0.18 0.53588 miRNATAP -0.24 0 NA
35 hsa-miR-194-5p EPHA5 2.24 0 -0.96 0.01733 MirTarget -0.43 0 NA
36 hsa-miR-194-5p ERBB4 2.24 0 -1.97 2.0E-5 miRNATAP -0.23 0.00317 NA
37 hsa-miR-194-5p ERG 2.24 0 0 0.99011 MirTarget -0.14 0 NA
38 hsa-miR-194-5p EYA4 2.24 0 0.3 0.36876 miRNATAP -0.22 0.00012 NA
39 hsa-miR-194-5p FAM63B 2.24 0 0.07 0.61635 miRNATAP -0.14 0 NA
40 hsa-miR-194-5p FOXO1 2.24 0 -0.14 0.33874 miRNATAP -0.11 0 24631529 Gα12gep oncogene inhibits FOXO1 in hepatocellular carcinoma as a consequence of miR 135b and miR 194 dysregulation; In addition Gα12QL repressed miR-194 cluster gene products 194/192/215 which contributed to MDM2-mediated FOXO1 repression; Moreover decrease of FOXO1 or miR-194 was statistically significant between stages T1 and T2 whereas increase of miR-135b discriminated tumor stage T3a versus T1/T2
41 hsa-miR-194-5p FOXP2 2.24 0 -1.9 1.0E-5 miRNATAP -0.63 0 NA
42 hsa-miR-194-5p FZD6 2.24 0 0.37 0.02474 MirTarget -0.11 4.0E-5 NA
43 hsa-miR-194-5p GAS7 2.24 0 -0.56 0.01602 mirMAP -0.35 0 NA
44 hsa-miR-194-5p GLCCI1 2.24 0 -1 0 MirTarget -0.12 1.0E-5 NA
45 hsa-miR-194-5p GPM6B 2.24 0 -2.16 0 miRNATAP -0.56 0 NA
46 hsa-miR-194-5p GRIK3 2.24 0 -3.21 0 mirMAP -0.59 0 NA
47 hsa-miR-194-5p GYG1 2.24 0 -0.45 0.00051 MirTarget; miRNATAP -0.22 0 NA
48 hsa-miR-194-5p HOOK3 2.24 0 0.27 0.09957 MirTarget -0.21 0 NA
49 hsa-miR-194-5p IGF1R 2.24 0 0.12 0.57112 miRNAWalker2 validate; miRTarBase; miRNATAP -0.14 6.0E-5 NA
50 hsa-miR-194-5p ITGA9 2.24 0 -0.83 0.00174 miRNAWalker2 validate; miRTarBase -0.3 0 NA
51 hsa-miR-194-5p ITPKB 2.24 0 -0.7 0.00106 MirTarget; miRNATAP -0.36 0 NA
52 hsa-miR-194-5p JMY 2.24 0 -0.27 0.06205 mirMAP -0.19 0 NA
53 hsa-miR-194-5p KAT6B 2.24 0 -0.48 0.00018 MirTarget; miRNATAP -0.12 0 NA
54 hsa-miR-194-5p KCNA1 2.24 0 -2.36 0.00043 mirMAP -0.76 0 NA
55 hsa-miR-194-5p KCTD20 2.24 0 0 0.97607 MirTarget -0.11 0 NA
56 hsa-miR-194-5p KIAA1644 2.24 0 -1.37 0.00031 mirMAP -0.49 0 NA
57 hsa-miR-194-5p KIF1B 2.24 0 -0.12 0.32258 mirMAP -0.1 0 NA
58 hsa-miR-194-5p KLF12 2.24 0 -0.39 0.08931 MirTarget -0.26 0 NA
59 hsa-miR-194-5p KLF15 2.24 0 -2.91 0 miRNATAP -0.47 0 NA
60 hsa-miR-194-5p KLF7 2.24 0 -0.38 0.04874 miRNATAP -0.16 0 NA
61 hsa-miR-194-5p LGI1 2.24 0 -4.11 0 MirTarget; miRNATAP -0.62 0 NA
62 hsa-miR-194-5p LHX6 2.24 0 -0.09 0.69193 miRNATAP -0.14 0.00022 NA
63 hsa-miR-194-5p LIMCH1 2.24 0 -0.92 1.0E-5 MirTarget -0.17 0 NA
64 hsa-miR-194-5p LNPEP 2.24 0 -0.18 0.24961 mirMAP -0.14 0 NA
65 hsa-miR-194-5p LPP 2.24 0 -0.46 0.04475 mirMAP -0.28 0 NA
66 hsa-miR-194-5p LRCH2 2.24 0 -0.76 0.00191 MirTarget -0.36 0 NA
67 hsa-miR-194-5p MAF 2.24 0 -1.26 0 miRNATAP -0.18 0 NA
68 hsa-miR-194-5p MAN1C1 2.24 0 -0.36 0.10568 miRNATAP -0.18 0 NA
69 hsa-miR-194-5p MAP1B 2.24 0 -0.56 0.05021 MirTarget -0.43 0 NA
70 hsa-miR-194-5p MAP2 2.24 0 -0.5 0.06746 MirTarget; miRNATAP -0.36 0 NA
71 hsa-miR-194-5p MAP3K3 2.24 0 -0.29 0.01565 miRNATAP -0.21 0 NA
72 hsa-miR-194-5p MBNL2 2.24 0 -0.2 0.12802 miRNATAP -0.1 0 NA
73 hsa-miR-194-5p MECP2 2.24 0 -0.15 0.15366 mirMAP; miRNATAP -0.17 0 NA
74 hsa-miR-194-5p MEF2C 2.24 0 -0.5 0.01448 miRNATAP -0.23 0 NA
75 hsa-miR-194-5p MEIS2 2.24 0 -0.88 4.0E-5 MirTarget; miRNATAP -0.17 0 NA
76 hsa-miR-194-5p MPP2 2.24 0 -0.98 0.00061 mirMAP -0.41 0 NA
77 hsa-miR-194-5p MTSS1 2.24 0 -0.81 0.00035 MirTarget; miRNATAP -0.22 0 NA
78 hsa-miR-194-5p MYH10 2.24 0 0.37 0.10713 miRNATAP -0.26 0 NA
79 hsa-miR-194-5p MYO5A 2.24 0 -0.09 0.61662 mirMAP -0.23 0 NA
80 hsa-miR-194-5p NBEA 2.24 0 -1.41 0.00027 miRNATAP -0.5 0 NA
81 hsa-miR-194-5p NFAT5 2.24 0 0.46 0.00066 miRNATAP -0.1 1.0E-5 NA
82 hsa-miR-194-5p NLGN4Y 2.24 0 -0.85 0.31856 MirTarget -0.46 0.00146 NA
83 hsa-miR-194-5p NR2F2 2.24 0 -0.14 0.3979 miRNATAP -0.12 1.0E-5 NA
84 hsa-miR-194-5p NRP1 2.24 0 0.58 0.00021 miRNATAP -0.12 0 NA
85 hsa-miR-194-5p NTRK3 2.24 0 -1.77 3.0E-5 mirMAP -0.46 0 NA
86 hsa-miR-194-5p OPCML 2.24 0 -2.5 0 miRNATAP -0.32 0 NA
87 hsa-miR-194-5p OSTM1 2.24 0 -0.25 0.0298 MirTarget -0.16 0 NA
88 hsa-miR-194-5p PACSIN1 2.24 0 -0.62 0.06496 mirMAP -0.16 0.0047 NA
89 hsa-miR-194-5p PAIP2 2.24 0 -0.51 0 MirTarget -0.16 0 NA
90 hsa-miR-194-5p PARVA 2.24 0 -0.48 0.00429 MirTarget -0.24 0 NA
91 hsa-miR-194-5p PER3 2.24 0 -1.21 0 miRNATAP -0.22 0 NA
92 hsa-miR-194-5p PFN2 2.24 0 -0.31 0.26876 miRNATAP -0.33 0 NA
93 hsa-miR-194-5p PHF1 2.24 0 -0.68 0 miRNATAP -0.17 0 NA
94 hsa-miR-194-5p PHLDA1 2.24 0 0.06 0.78159 MirTarget -0.12 0.0005 NA
95 hsa-miR-194-5p PIP4K2A 2.24 0 0.05 0.65696 MirTarget -0.11 0 NA
96 hsa-miR-194-5p PITPNM2 2.24 0 -0.47 0.00216 MirTarget; miRNATAP -0.21 0 NA
97 hsa-miR-194-5p PJA2 2.24 0 -0.72 0 MirTarget -0.21 0 NA
98 hsa-miR-194-5p PKD2 2.24 0 -0.24 0.21741 miRNATAP -0.3 0 NA
99 hsa-miR-194-5p PPFIBP1 2.24 0 0.08 0.54797 MirTarget -0.12 0 NA
100 hsa-miR-194-5p PPP1R12B 2.24 0 -1.14 0.00076 mirMAP -0.44 0 NA
101 hsa-miR-194-5p PPP2R2C 2.24 0 -0.96 0.07428 miRNATAP -0.5 0 NA
102 hsa-miR-194-5p PRICKLE2 2.24 0 -1.11 0.00011 miRNATAP -0.48 0 NA
103 hsa-miR-194-5p PRKCB 2.24 0 -1.31 2.0E-5 miRNATAP -0.32 0 NA
104 hsa-miR-194-5p PTPN13 2.24 0 -1.21 0 miRNAWalker2 validate; miRTarBase -0.45 0 NA
105 hsa-miR-194-5p PTPRD 2.24 0 -1.01 0.00064 miRNATAP -0.22 1.0E-5 NA
106 hsa-miR-194-5p RAB11FIP2 2.24 0 -0.26 0.0617 MirTarget; miRNATAP -0.12 0 NA
107 hsa-miR-194-5p RAB6B 2.24 0 -1.2 0 miRNATAP -0.29 0 NA
108 hsa-miR-194-5p RERE 2.24 0 -0.18 0.12411 miRNATAP -0.11 0 NA
109 hsa-miR-194-5p REV3L 2.24 0 0.06 0.62263 miRNATAP -0.12 0 NA
110 hsa-miR-194-5p SAMD4A 2.24 0 -0.13 0.55532 miRNATAP -0.27 0 NA
111 hsa-miR-194-5p SAMD8 2.24 0 -0.11 0.40369 MirTarget -0.11 0 NA
112 hsa-miR-194-5p SATB1 2.24 0 -0.9 2.0E-5 miRNATAP -0.26 0 NA
113 hsa-miR-194-5p SH3PXD2A 2.24 0 0.1 0.49534 mirMAP -0.18 0 NA
114 hsa-miR-194-5p SLC16A9 2.24 0 -2.32 0 miRNAWalker2 validate -0.19 0.01671 NA
115 hsa-miR-194-5p SLC25A27 2.24 0 -0.59 0.08043 MirTarget -0.32 0 NA
116 hsa-miR-194-5p SLC30A8 2.24 0 -2.66 0 MirTarget; miRNATAP -0.5 0 NA
117 hsa-miR-194-5p SLC35F3 2.24 0 -1.63 5.0E-5 miRNATAP -0.28 4.0E-5 NA
118 hsa-miR-194-5p SLC7A5 2.24 0 0.29 0.24318 MirTarget -0.13 0.00299 NA
119 hsa-miR-194-5p SNX1 2.24 0 -0.51 0 MirTarget -0.13 0 NA
120 hsa-miR-194-5p SNX29 2.24 0 -0.34 0.01371 miRNATAP -0.23 0 NA
121 hsa-miR-194-5p SOCS2 2.24 0 -1.1 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.15 0 22102710 Functional studies indicated that CDKN1A/p21 and SOCS2 expression is directly regulated by miR-20a/-20b and miR-194 respectively; miR-20a/b and miR-194 target CDKN1A and SOCS2 in follicular lymphoma potentially contributing to tumor cell proliferation and survival
122 hsa-miR-194-5p SOX5 2.24 0 -1.09 4.0E-5 miRNAWalker2 validate; miRTarBase -0.31 0 NA
123 hsa-miR-194-5p SPOCK3 2.24 0 -2.32 0 miRNATAP -0.5 0 NA
124 hsa-miR-194-5p STAT5B 2.24 0 -0.18 0.1082 miRNATAP -0.13 0 NA
125 hsa-miR-194-5p TCEAL4 2.24 0 -0.41 0.01183 MirTarget -0.22 0 NA
126 hsa-miR-194-5p TDRD9 2.24 0 -0.58 0.09038 MirTarget -0.13 0.02967 NA
127 hsa-miR-194-5p TEAD1 2.24 0 -0.18 0.334 MirTarget -0.27 0 NA
128 hsa-miR-194-5p TJP1 2.24 0 -0.13 0.31513 miRNATAP -0.13 0 NA
129 hsa-miR-194-5p TMEM108 2.24 0 -1.31 0 MirTarget -0.36 0 NA
130 hsa-miR-194-5p TMEM43 2.24 0 0.01 0.8988 MirTarget; miRNATAP -0.18 0 NA
131 hsa-miR-194-5p TRIM23 2.24 0 -0.34 0.00212 MirTarget -0.17 0 26221053 Transcripts encoding tripartite motif containing 23 TRIM23 a ubiquitin ligase involved in NF-κB activation and chromosome 21 open reading frame 91 C21ORF91 a protein of unknown function were identified as direct targets of miR-194 in HCC cells; knocking down either protein decreased the activity of a luciferase NF-κB reporter
132 hsa-miR-194-5p TRPS1 2.24 0 -0.19 0.44109 MirTarget; miRNATAP -0.41 0 NA
133 hsa-miR-194-5p TSHZ1 2.24 0 -0.61 3.0E-5 miRNATAP -0.17 0 NA
134 hsa-miR-194-5p TUSC3 2.24 0 -0.77 0.00052 MirTarget -0.32 0 NA
135 hsa-miR-194-5p UNC80 2.24 0 -1.93 0 miRNATAP -0.32 1.0E-5 NA
136 hsa-miR-194-5p WTIP 2.24 0 -0.2 0.33494 mirMAP -0.18 0 NA
137 hsa-miR-194-5p ZC3H6 2.24 0 -0.42 0.00729 mirMAP -0.16 0 NA
138 hsa-miR-194-5p ZCCHC5 2.24 0 -0.95 0.05183 miRNATAP -0.58 0 NA
139 hsa-miR-194-5p ZEB1 2.24 0 -0.47 0.04764 miRNATAP -0.36 0 NA
140 hsa-miR-194-5p ZFHX3 2.24 0 0.39 0.01363 MirTarget; miRNATAP -0.16 0 NA
141 hsa-miR-194-5p ZFHX4 2.24 0 0.02 0.95574 MirTarget; miRNATAP -0.36 0 NA
142 hsa-miR-194-5p ZNF25 2.24 0 -0.52 0.00115 miRNATAP -0.26 0 NA
143 hsa-miR-194-5p ZNF516 2.24 0 -0.53 0.0017 MirTarget; miRNATAP -0.2 0 NA
144 hsa-miR-194-5p ZNF532 2.24 0 0.41 0.01627 miRNATAP -0.24 0 NA
145 hsa-miR-194-5p ZNF548 2.24 0 -0.08 0.53946 MirTarget -0.12 0 NA
146 hsa-miR-194-5p ZNF615 2.24 0 -0.53 0.00435 MirTarget -0.2 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 NEUROGENESIS 34 1402 3.543e-10 1.648e-06
2 CENTRAL NERVOUS SYSTEM DEVELOPMENT 23 872 8.784e-08 0.0002044
3 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 28 1275 1.384e-07 0.0002146
4 FOREBRAIN DEVELOPMENT 14 357 3.717e-07 0.0003578
5 NEURON DIFFERENTIATION 22 874 3.845e-07 0.0003578
6 HEAD DEVELOPMENT 19 709 1.03e-06 0.0007988
7 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 30 1672 3.287e-06 0.002185
8 LOCOMOTION 23 1114 5.952e-06 0.003462
9 NEURON DEVELOPMENT 17 687 1.134e-05 0.005646
10 COGNITION 10 251 1.61e-05 0.005646
11 CELL PART MORPHOGENESIS 16 633 1.612e-05 0.005646
12 NEURON MIGRATION 7 110 1.625e-05 0.005646
13 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 12 368 1.699e-05 0.005646
14 CELL DEVELOPMENT 26 1426 1.265e-05 0.005646
15 DENDRITE DEVELOPMENT 6 79 2.448e-05 0.007119
16 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 14 513 2.441e-05 0.007119
17 REGULATION OF CELL DIFFERENTIATION 26 1492 2.766e-05 0.007571
18 CELL PROJECTION ORGANIZATION 19 902 3.187e-05 0.008239
19 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 17 750 3.466e-05 0.008489
20 NEURON PROJECTION MORPHOGENESIS 12 402 4.034e-05 0.008937
21 REGULATION OF CELL DEVELOPMENT 18 836 3.94e-05 0.008937
22 NEURON PROJECTION DEVELOPMENT 14 545 4.716e-05 0.009541
23 TELENCEPHALON DEVELOPMENT 9 228 4.642e-05 0.009541
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 29 1199 9.642e-09 8.958e-06
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 17 629 3.563e-06 0.001655
3 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 6 64 7.223e-06 0.002237
4 ZINC ION BINDING 23 1155 1.071e-05 0.002487
5 SEQUENCE SPECIFIC DNA BINDING 21 1037 2.114e-05 0.003928
6 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 6 81 2.824e-05 0.003999
7 CYTOSKELETAL PROTEIN BINDING 18 819 3.013e-05 0.003999
8 MACROMOLECULAR COMPLEX BINDING 24 1399 7.534e-05 0.008748
9 CHROMATIN BINDING 12 435 8.577e-05 0.008854
10 REGULATORY REGION NUCLEIC ACID BINDING 17 818 0.0001008 0.009367
NumGOOverlapSizeP ValueAdj. P Value
1 SYNAPSE 19 754 2.548e-06 0.001488
2 CELL JUNCTION 23 1151 1.013e-05 0.002957

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04310_Wnt_signaling_pathway 6 151 0.0008537 0.1537
2 hsa04012_ErbB_signaling_pathway 4 87 0.003796 0.3416
3 hsa04360_Axon_guidance 4 130 0.01524 0.6157
4 hsa04530_Tight_junction 4 133 0.01644 0.6157
5 hsa04070_Phosphatidylinositol_signaling_system 3 78 0.01947 0.6157
6 hsa04810_Regulation_of_actin_cytoskeleton 5 214 0.02052 0.6157
7 hsa04390_Hippo_signaling_pathway 4 154 0.02649 0.6811
8 hsa04912_GnRH_signaling_pathway 3 101 0.03782 0.7371
9 hsa04916_Melanogenesis 3 101 0.03782 0.7371
10 hsa04020_Calcium_signaling_pathway 4 177 0.04095 0.7371
11 hsa00510_N.Glycan_biosynthesis 2 49 0.04979 0.7937
12 hsa04510_Focal_adhesion 4 200 0.05911 0.7937
13 hsa04144_Endocytosis 4 203 0.06175 0.7937
14 hsa00562_Inositol_phosphate_metabolism 2 57 0.0651 0.7937
15 hsa04722_Neurotrophin_signaling_pathway 3 127 0.06614 0.7937
16 hsa04514_Cell_adhesion_molecules_.CAMs. 3 136 0.07767 0.871
17 hsa04720_Long.term_potentiation 2 70 0.09274 0.871
18 hsa04730_Long.term_depression 2 70 0.09274 0.871
19 hsa04520_Adherens_junction 2 73 0.09953 0.871
20 hsa04971_Gastric_acid_secretion 2 74 0.1018 0.871
21 hsa04662_B_cell_receptor_signaling_pathway 2 75 0.1041 0.871
22 hsa04370_VEGF_signaling_pathway 2 76 0.1065 0.871
23 hsa04010_MAPK_signaling_pathway 4 268 0.1332 0.9588
24 hsa04540_Gap_junction 2 90 0.1403 0.9713
25 hsa04666_Fc_gamma_R.mediated_phagocytosis 2 95 0.1529 0.9975
26 hsa04114_Oocyte_meiosis 2 114 0.2024 1
27 hsa04270_Vascular_smooth_muscle_contraction 2 116 0.2077 1
28 hsa04650_Natural_killer_cell_mediated_cytotoxicity 2 136 0.2616 1
29 hsa04910_Insulin_signaling_pathway 2 138 0.267 1
30 hsa04630_Jak.STAT_signaling_pathway 2 155 0.3128 1
31 hsa04141_Protein_processing_in_endoplasmic_reticulum 2 168 0.3475 1
32 hsa04062_Chemokine_signaling_pathway 2 189 0.4022 1
33 hsa04151_PI3K_AKT_signaling_pathway 3 351 0.4738 1
34 hsa04014_Ras_signaling_pathway 2 236 0.5159 1

Quest ID: 22c371a202c90b8391e85845bf088cbe