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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-139-5p ALDH3B2 -1.53 0 2.64 1.0E-5 miRanda -0.23 0.03345 NA
2 hsa-miR-139-5p ALG11 -1.53 0 0.45 0.03472 miRanda -0.12 0.00188 NA
3 hsa-miR-139-5p AMMECR1 -1.53 0 0.72 0.00063 miRanda -0.17 1.0E-5 NA
4 hsa-miR-139-5p AMPD3 -1.53 0 0.05 0.81987 miRanda -0.12 0.00198 NA
5 hsa-miR-139-5p ANO1 -1.53 0 1.02 0.02235 miRanda -0.18 0.02021 NA
6 hsa-miR-139-5p APOOL -1.53 0 -0.23 0.29879 miRanda -0.14 0.00023 NA
7 hsa-miR-139-5p ARHGAP32 -1.53 0 0.68 0.00492 miRanda -0.13 0.00371 NA
8 hsa-miR-139-5p ARL6IP1 -1.53 0 0.96 0 miRanda -0.1 0.00066 NA
9 hsa-miR-139-5p ARL6IP6 -1.53 0 0.64 4.0E-5 miRanda -0.12 3.0E-5 NA
10 hsa-miR-139-5p ASB7 -1.53 0 0.19 0.06556 PITA; miRanda -0.1 0 NA
11 hsa-miR-139-5p ATF7IP -1.53 0 -0 0.99785 miRanda -0.11 0.00026 NA
12 hsa-miR-139-5p ATL2 -1.53 0 -0.08 0.64926 MirTarget; miRanda; miRNATAP -0.12 6.0E-5 NA
13 hsa-miR-139-5p BARX2 -1.53 0 2.53 0.00089 miRanda -0.33 0.01546 NA
14 hsa-miR-139-5p BAZ1A -1.53 0 0.41 0.01012 miRanda -0.16 0 NA
15 hsa-miR-139-5p BICD1 -1.53 0 0.12 0.64772 miRanda -0.11 0.02217 NA
16 hsa-miR-139-5p BLZF1 -1.53 0 -0.38 0.01298 miRanda -0.1 0.00018 NA
17 hsa-miR-139-5p BUB1 -1.53 0 2.99 0 miRanda -0.25 0 NA
18 hsa-miR-139-5p CASP5 -1.53 0 0.89 0.08562 miRanda -0.2 0.02854 NA
19 hsa-miR-139-5p CCDC120 -1.53 0 0.85 1.0E-5 miRanda -0.12 0.00034 NA
20 hsa-miR-139-5p CCL20 -1.53 0 0.33 0.64296 miRanda -0.3 0.01758 NA
21 hsa-miR-139-5p CCNB1 -1.53 0 2.59 0 miRanda -0.23 0 NA
22 hsa-miR-139-5p CCNF -1.53 0 1.96 0 miRanda -0.12 0.00179 NA
23 hsa-miR-139-5p CCT5 -1.53 0 0.96 0 miRanda -0.11 0.0002 NA
24 hsa-miR-139-5p CD274 -1.53 0 0.06 0.90454 miRanda -0.31 0.00052 NA
25 hsa-miR-139-5p CDCA7 -1.53 0 1.72 0 miRanda -0.21 0.00043 NA
26 hsa-miR-139-5p CDCA8 -1.53 0 3.31 0 miRanda -0.23 1.0E-5 NA
27 hsa-miR-139-5p CDH1 -1.53 0 2.71 0 PITA; miRanda -0.26 0.00181 NA
28 hsa-miR-139-5p CDK1 -1.53 0 3.39 0 miRanda -0.24 0 NA
29 hsa-miR-139-5p CELSR1 -1.53 0 0.45 0.27081 miRanda -0.14 0.04646 NA
30 hsa-miR-139-5p CENPF -1.53 0 3.04 0 miRanda -0.3 0 NA
31 hsa-miR-139-5p CENPW -1.53 0 1.45 0 miRanda -0.14 0.00288 NA
32 hsa-miR-139-5p CHAC2 -1.53 0 0.98 2.0E-5 miRanda -0.14 0.00096 NA
33 hsa-miR-139-5p CHD7 -1.53 0 0.67 0.00044 PITA; miRanda; miRNATAP -0.15 1.0E-5 NA
34 hsa-miR-139-5p CHEK1 -1.53 0 1.6 0 miRanda -0.12 0.0025 NA
35 hsa-miR-139-5p CIT -1.53 0 2.11 0 miRanda -0.21 1.0E-5 NA
36 hsa-miR-139-5p CKS2 -1.53 0 2.01 0 miRanda -0.14 0.00061 NA
37 hsa-miR-139-5p CLEC5A -1.53 0 2.07 1.0E-5 miRanda -0.31 0.0002 NA
38 hsa-miR-139-5p CNIH4 -1.53 0 0.54 0 miRanda -0.1 0 NA
39 hsa-miR-139-5p CNKSR1 -1.53 0 2.32 0 miRanda -0.24 4.0E-5 NA
40 hsa-miR-139-5p COL11A1 -1.53 0 4.69 0 miRanda -0.61 6.0E-5 NA
41 hsa-miR-139-5p CPA4 -1.53 0 3.23 2.0E-5 miRanda -0.47 0.00063 NA
42 hsa-miR-139-5p CTSC -1.53 0 0.86 0.00468 miRanda -0.13 0.0146 NA
43 hsa-miR-139-5p CTTN -1.53 0 0.37 0.06349 miRanda -0.1 0.00327 NA
44 hsa-miR-139-5p CXCL10 -1.53 0 1.86 0.00573 miRanda -0.41 0.00061 NA
45 hsa-miR-139-5p CXCL11 -1.53 0 2.31 0.00121 miRanda -0.46 0.00027 NA
46 hsa-miR-139-5p DCAF4L1 -1.53 0 1.07 0.00091 miRanda -0.13 0.02199 NA
47 hsa-miR-139-5p DCBLD1 -1.53 0 1.15 0 miRanda -0.18 2.0E-5 NA
48 hsa-miR-139-5p DDX11 -1.53 0 1.5 0 miRanda -0.12 0.00039 NA
49 hsa-miR-139-5p DDX58 -1.53 0 0.2 0.48431 miRanda; mirMAP -0.16 0.00241 NA
50 hsa-miR-139-5p DENND1B -1.53 0 0.36 0.11498 miRanda -0.12 0.00437 NA
51 hsa-miR-139-5p DEPDC1 -1.53 0 3.17 0 miRanda -0.28 0 NA
52 hsa-miR-139-5p DOCK5 -1.53 0 -0.05 0.85865 miRanda -0.12 0.0187 NA
53 hsa-miR-139-5p DSC2 -1.53 0 1.52 0.00517 MirTarget; miRanda -0.29 0.00268 NA
54 hsa-miR-139-5p DSG1 -1.53 0 0.69 0.38732 miRanda -0.32 0.02598 NA
55 hsa-miR-139-5p DTX3L -1.53 0 0.74 6.0E-5 miRanda -0.15 0 NA
56 hsa-miR-139-5p E2F7 -1.53 0 2.72 0 miRanda -0.34 0 NA
57 hsa-miR-139-5p E2F8 -1.53 0 2.88 0 miRanda -0.18 0.00398 NA
58 hsa-miR-139-5p EIF2AK2 -1.53 0 0.89 1.0E-5 mirMAP -0.2 0 NA
59 hsa-miR-139-5p EME1 -1.53 0 3.13 0 MirTarget; miRanda -0.2 8.0E-5 NA
60 hsa-miR-139-5p ERMP1 -1.53 0 0.59 0.04687 miRanda -0.12 0.02647 NA
61 hsa-miR-139-5p ETV7 -1.53 0 1.67 0 miRanda -0.24 0.00011 NA
62 hsa-miR-139-5p EZH2 -1.53 0 2.33 0 miRanda -0.19 3.0E-5 NA
63 hsa-miR-139-5p FAM63B -1.53 0 -0.55 0.03992 miRanda -0.1 0.03546 NA
64 hsa-miR-139-5p FAM83D -1.53 0 0.49 0.09144 miRanda -0.13 0.01377 NA
65 hsa-miR-139-5p FAM84B -1.53 0 0.89 0.00081 PITA; miRanda -0.12 0.01445 NA
66 hsa-miR-139-5p FAM91A1 -1.53 0 0.55 0.00021 MirTarget; miRanda -0.11 3.0E-5 NA
67 hsa-miR-139-5p FANCA -1.53 0 2.96 0 miRanda -0.17 0.00044 NA
68 hsa-miR-139-5p FANCB -1.53 0 1.98 0 miRanda -0.22 0 NA
69 hsa-miR-139-5p FHOD3 -1.53 0 -0.76 0.03983 miRanda -0.13 0.04352 NA
70 hsa-miR-139-5p FMR1 -1.53 0 0.2 0.13475 MirTarget; PITA; miRanda; miRNATAP -0.13 0 NA
71 hsa-miR-139-5p FRMD6 -1.53 0 -0.93 0.00183 miRanda -0.14 0.0072 NA
72 hsa-miR-139-5p FZD6 -1.53 0 0.39 0.09232 miRanda -0.19 1.0E-5 NA
73 hsa-miR-139-5p GALNT3 -1.53 0 1.95 0 MirTarget; PITA; miRanda; miRNATAP -0.2 0.00189 NA
74 hsa-miR-139-5p GBP4 -1.53 0 0.37 0.3093 miRanda -0.18 0.00542 NA
75 hsa-miR-139-5p GBP5 -1.53 0 0.91 0.15545 miRanda -0.36 0.00144 NA
76 hsa-miR-139-5p GINS1 -1.53 0 2.66 0 miRanda -0.21 0 NA
77 hsa-miR-139-5p GMCL1 -1.53 0 0.26 0.22721 miRanda -0.11 0.00598 NA
78 hsa-miR-139-5p GOLGA8A -1.53 0 1.1 0.00088 miRanda -0.13 0.02433 NA
79 hsa-miR-139-5p GOLGA8B -1.53 0 1.48 0.00014 miRanda -0.14 0.04617 NA
80 hsa-miR-139-5p GPD2 -1.53 0 0.54 0.00217 miRanda -0.14 0 NA
81 hsa-miR-139-5p GPR19 -1.53 0 2.07 0 miRanda -0.18 0.00585 NA
82 hsa-miR-139-5p GPSM2 -1.53 0 0.59 0.00498 miRanda -0.15 0.0001 NA
83 hsa-miR-139-5p GSK3B -1.53 0 0.41 0.00051 mirMAP -0.1 0 NA
84 hsa-miR-139-5p GTSE1 -1.53 0 3.52 0 miRanda -0.22 6.0E-5 NA
85 hsa-miR-139-5p HCP5 -1.53 0 0.7 0.08729 miRanda -0.12 0.03983 NA
86 hsa-miR-139-5p HDGF -1.53 0 0.88 0 PITA; miRanda; miRNATAP -0.1 3.0E-5 NA
87 hsa-miR-139-5p HEPHL1 -1.53 0 2.06 0.00746 miRanda -0.59 1.0E-5 NA
88 hsa-miR-139-5p HIST2H4A -1.53 0 1.58 0 miRanda -0.16 0.00856 NA
89 hsa-miR-139-5p HPRT1 -1.53 0 0.8 0 miRanda -0.17 0 NA
90 hsa-miR-139-5p HSPH1 -1.53 0 0.46 0.01027 miRanda -0.13 6.0E-5 NA
91 hsa-miR-139-5p IBSP -1.53 0 3.42 0 miRanda -0.22 0.02795 NA
92 hsa-miR-139-5p IL1RAP -1.53 0 0.69 0.05618 miRanda -0.22 0.00071 NA
93 hsa-miR-139-5p IRF1 -1.53 0 0.08 0.77621 miRanda -0.16 0.00196 NA
94 hsa-miR-139-5p ITGA2 -1.53 0 0.78 0.03601 PITA; miRanda -0.25 0.00016 NA
95 hsa-miR-139-5p ITGA3 -1.53 0 0.85 0.02 PITA; miRanda -0.26 5.0E-5 NA
96 hsa-miR-139-5p JARID2 -1.53 0 0.46 0.02167 miRanda -0.12 0.00061 NA
97 hsa-miR-139-5p KCND2 -1.53 0 0.88 0.06057 MirTarget; miRanda -0.21 0.01039 NA
98 hsa-miR-139-5p KDM3A -1.53 0 0.11 0.46659 miRanda -0.15 0 NA
99 hsa-miR-139-5p KDM5B -1.53 0 0.43 0.00766 miRanda -0.12 2.0E-5 NA
100 hsa-miR-139-5p KIAA1524 -1.53 0 1.77 0 miRanda -0.2 1.0E-5 NA
101 hsa-miR-139-5p KIF15 -1.53 0 2.93 0 miRanda -0.25 1.0E-5 NA
102 hsa-miR-139-5p KIF18A -1.53 0 2.63 0 miRanda -0.27 0 NA
103 hsa-miR-139-5p KIF23 -1.53 0 2.71 0 miRanda -0.27 0 NA
104 hsa-miR-139-5p KLF7 -1.53 0 -0.4 0.17032 mirMAP -0.18 0.00064 NA
105 hsa-miR-139-5p KPNA2 -1.53 0 1.67 0 miRanda -0.14 0.00067 NA
106 hsa-miR-139-5p KRT74 -1.53 0 0.8 0.14669 miRanda -0.28 0.00454 NA
107 hsa-miR-139-5p KTN1 -1.53 0 -0.07 0.67114 miRanda -0.11 3.0E-5 NA
108 hsa-miR-139-5p LCOR -1.53 0 -0.36 0.27591 miRanda; miRNATAP -0.16 0.00671 NA
109 hsa-miR-139-5p LCORL -1.53 0 0.11 0.54124 miRanda -0.12 0.00026 NA
110 hsa-miR-139-5p LGR5 -1.53 0 0.82 0.25477 miRanda -0.44 0.00065 NA
111 hsa-miR-139-5p LHX1 -1.53 0 1.91 0.00353 miRNATAP -0.34 0.0035 NA
112 hsa-miR-139-5p LIN9 -1.53 0 1.3 0 miRanda -0.18 0 NA
113 hsa-miR-139-5p LRRC8B -1.53 0 0.7 0.00036 miRanda -0.1 0.00337 NA
114 hsa-miR-139-5p MAD2L1 -1.53 0 2.01 0 miRanda -0.16 0.00049 NA
115 hsa-miR-139-5p MAP3K13 -1.53 0 0.08 0.78946 miRanda -0.14 0.00876 NA
116 hsa-miR-139-5p MAP3K2 -1.53 0 -0.46 0.01831 miRanda; mirMAP -0.11 0.00249 NA
117 hsa-miR-139-5p MAPK6 -1.53 0 -0.19 0.3655 miRanda -0.14 0.00015 NA
118 hsa-miR-139-5p MASTL -1.53 0 0.9 0 miRanda -0.11 0.00016 NA
119 hsa-miR-139-5p MCM2 -1.53 0 2 0 miRanda -0.16 0.00036 NA
120 hsa-miR-139-5p MCTP2 -1.53 0 0.36 0.30823 miRanda -0.18 0.00472 NA
121 hsa-miR-139-5p MED14 -1.53 0 0.07 0.60842 miRanda -0.12 0 NA
122 hsa-miR-139-5p MET -1.53 0 0.84 0.00151 miRanda -0.15 0.00146 NA
123 hsa-miR-139-5p MEX3A -1.53 0 3.12 0 PITA; miRanda; miRNATAP -0.18 0.02059 NA
124 hsa-miR-139-5p MNX1 -1.53 0 3.42 0 miRanda -0.2 0.04674 NA
125 hsa-miR-139-5p MSH2 -1.53 0 0.9 0 miRanda -0.13 2.0E-5 NA
126 hsa-miR-139-5p MTBP -1.53 0 1.78 0 miRanda -0.24 0 NA
127 hsa-miR-139-5p MXD1 -1.53 0 -0.44 0.10148 miRanda -0.12 0.01157 NA
128 hsa-miR-139-5p NBEAL1 -1.53 0 -0.82 0.0043 miRanda -0.13 0.01309 NA
129 hsa-miR-139-5p NF1 -1.53 0 0.07 0.64531 miRanda -0.11 8.0E-5 NA
130 hsa-miR-139-5p NFE2L3 -1.53 0 1.66 0 miRanda -0.13 0.0166 NA
131 hsa-miR-139-5p NKX3-2 -1.53 0 2.29 0 miRanda -0.26 0.00368 NA
132 hsa-miR-139-5p NMI -1.53 0 0.62 0.00244 miRanda -0.13 0.00058 NA
133 hsa-miR-139-5p OAS2 -1.53 0 0.97 0.0107 miRanda -0.21 0.00247 NA
134 hsa-miR-139-5p OAS3 -1.53 0 1.29 0 mirMAP -0.24 0 NA
135 hsa-miR-139-5p OIP5 -1.53 0 3.1 0 miRanda -0.23 3.0E-5 NA
136 hsa-miR-139-5p OPN3 -1.53 0 1.09 2.0E-5 miRanda -0.1 0.02466 NA
137 hsa-miR-139-5p ORAOV1 -1.53 0 0.58 0.01806 miRanda -0.11 0.00898 NA
138 hsa-miR-139-5p OTUB2 -1.53 0 1.32 0 miRanda -0.13 0.00462 NA
139 hsa-miR-139-5p PARP2 -1.53 0 0.52 0.0001 miRanda -0.11 0 NA
140 hsa-miR-139-5p PCDHGA1 -1.53 0 0.21 0.58526 miRanda -0.16 0.02055 NA
141 hsa-miR-139-5p PCDHGB1 -1.53 0 -0.34 0.51109 miRanda -0.27 0.00324 NA
142 hsa-miR-139-5p PCDHGC5 -1.53 0 -0.32 0.51872 miRanda -0.21 0.01789 NA
143 hsa-miR-139-5p PDK1 -1.53 0 0.44 0.02975 MirTarget; miRanda -0.15 3.0E-5 NA
144 hsa-miR-139-5p PHF6 -1.53 0 0.62 7.0E-5 MirTarget; PITA; miRanda -0.13 0 NA
145 hsa-miR-139-5p PLAG1 -1.53 0 0.79 0.05456 PITA; mirMAP -0.17 0.01868 NA
146 hsa-miR-139-5p POP1 -1.53 0 0.77 1.0E-5 miRanda -0.1 0.00099 NA
147 hsa-miR-139-5p PPAT -1.53 0 0.81 0 miRanda -0.13 3.0E-5 NA
148 hsa-miR-139-5p PPBP -1.53 0 -0.11 0.84483 miRanda -0.23 0.02398 NA
149 hsa-miR-139-5p PRC1 -1.53 0 2.27 0 miRanda -0.22 0 NA
150 hsa-miR-139-5p PRR11 -1.53 0 2.86 0 miRanda -0.35 7.0E-5 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL CYCLE 51 1316 5.46e-15 2.541e-11
2 CELL CYCLE PROCESS 43 1081 4.658e-13 1.084e-09
3 MITOTIC CELL CYCLE 34 766 9.522e-12 1.477e-08
4 CHROMOSOME ORGANIZATION 36 1009 9.623e-10 1.119e-06
5 NEGATIVE REGULATION OF CELL CYCLE PROCESS 16 214 3.194e-09 2.972e-06
6 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 15 199 9e-09 6.98e-06
7 CHROMOSOME SEGREGATION 17 272 1.512e-08 7.817e-06
8 ORGANELLE FISSION 23 496 1.243e-08 7.817e-06
9 SISTER CHROMATID SEGREGATION 14 176 1.436e-08 7.817e-06
10 NEGATIVE REGULATION OF CELL DIVISION 9 60 2.386e-08 1.11e-05
11 MITOTIC NUCLEAR DIVISION 19 361 3.383e-08 1.431e-05
12 DNA METABOLIC PROCESS 28 758 4.142e-08 1.606e-05
13 CELL CYCLE CHECKPOINT 14 194 4.933e-08 1.766e-05
14 NUCLEAR CHROMOSOME SEGREGATION 15 228 5.56e-08 1.848e-05
15 MITOTIC CELL CYCLE CHECKPOINT 12 139 6.41e-08 1.988e-05
16 CELL DIVISION 21 460 7.203e-08 2.095e-05
17 REGULATION OF CELL CYCLE PROCESS 22 558 4.358e-07 0.0001193
18 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 18 387 4.901e-07 0.0001267
19 REGULATION OF CELL DIVISION 15 272 5.46e-07 0.0001316
20 NEGATIVE REGULATION OF CELL CYCLE 19 433 5.656e-07 0.0001316
21 CELL PROLIFERATION 24 672 7.535e-07 0.000167
22 NEGATIVE REGULATION OF NUCLEAR DIVISION 7 46 8.126e-07 0.0001719
23 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 11 146 9.032e-07 0.0001827
24 REGULATION OF CELL CYCLE 29 949 1.225e-06 0.0002374
25 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 43 1784 1.717e-06 0.0003197
26 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 6 34 2.063e-06 0.0003692
27 CELLULAR RESPONSE TO STRESS 39 1565 2.578e-06 0.0004442
28 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 23 684 3.567e-06 0.0005927
29 POSITIVE REGULATION OF GENE EXPRESSION 41 1733 4.971e-06 0.0007976
30 RESPONSE TO MECHANICAL STIMULUS 12 210 5.293e-06 0.000821
31 DNA INTEGRITY CHECKPOINT 10 146 6.706e-06 0.001007
32 SPINDLE CHECKPOINT 5 25 7.956e-06 0.001157
33 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 23 720 8.251e-06 0.001163
34 MITOTIC SISTER CHROMATID SEGREGATION 8 91 9.21e-06 0.00126
35 REPRODUCTION 33 1297 1.111e-05 0.001476
36 GLAND DEVELOPMENT 16 395 1.238e-05 0.001601
37 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 41 1805 1.326e-05 0.001624
38 MITOTIC SPINDLE ORGANIZATION 7 69 1.313e-05 0.001624
39 MITOTIC DNA INTEGRITY CHECKPOINT 8 100 1.848e-05 0.002205
40 REGULATION OF CELL CYCLE PHASE TRANSITION 14 321 1.941e-05 0.002258
41 POSITIVE REGULATION OF CELL CYCLE PROCESS 12 247 2.698e-05 0.003062
42 DNA REPAIR 17 480 3.684e-05 0.004081
43 SISTER CHROMATID COHESION 8 111 3.941e-05 0.004264
44 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 9 147 4.732e-05 0.005004
45 TUBE DEVELOPMENT 18 552 6.336e-05 0.006551
46 REPRODUCTIVE SYSTEM DEVELOPMENT 15 408 7.018e-05 0.007099
47 REGULATION OF MITOTIC CELL CYCLE 16 468 9.451e-05 0.009356
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 33 1199 2.12e-06 0.0009894
2 DOUBLE STRANDED DNA BINDING 25 764 2.13e-06 0.0009894
3 ADENYL NUCLEOTIDE BINDING 37 1514 7.563e-06 0.002342
4 SEQUENCE SPECIFIC DNA BINDING 28 1037 1.919e-05 0.004457
5 RIBONUCLEOTIDE BINDING 41 1860 2.679e-05 0.004978
NumGOOverlapSizeP ValueAdj. P Value
1 CHROMOSOME 34 880 3.872e-10 2.261e-07
2 CHROMOSOMAL REGION 19 330 7.998e-09 2.336e-06
3 SPINDLE 17 289 3.686e-08 7.176e-06
4 MITOTIC SPINDLE 8 55 1.873e-07 2.735e-05
5 NUCLEAR CHROMOSOME 20 523 2.378e-06 0.0002777
6 MICROTUBULE CYTOSKELETON 30 1068 4.341e-06 0.0004191
7 CHROMOSOME CENTROMERIC REGION 11 174 5.024e-06 0.0004191
8 CONDENSED CHROMOSOME 11 195 1.481e-05 0.001081
9 CHROMATIN 16 441 4.707e-05 0.003054
10 KINETOCHORE 8 120 6.873e-05 0.004014
11 SPINDLE POLE 8 126 9.693e-05 0.005146
12 MIDBODY 8 132 0.0001341 0.006527

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04110_Cell_cycle 8 128 0.0001082 0.01948
2 hsa04512_ECM.receptor_interaction 5 85 0.002831 0.2548
3 hsa04510_Focal_adhesion 7 200 0.007994 0.4796
4 hsa04914_Progesterone.mediated_oocyte_maturation 4 87 0.01729 0.778
5 hsa03430_Mismatch_repair 2 23 0.02774 0.9393
6 hsa04390_Hippo_signaling_pathway 5 154 0.03131 0.9393
7 hsa04114_Oocyte_meiosis 4 114 0.04105 0.9846
8 hsa04115_p53_signaling_pathway 3 69 0.04376 0.9846
9 hsa04520_Adherens_junction 3 73 0.05029 1
10 hsa03030_DNA_replication 2 36 0.0628 1
11 hsa04062_Chemokine_signaling_pathway 5 189 0.0647 1
12 hsa04310_Wnt_signaling_pathway 4 151 0.09342 1
13 hsa00510_N.Glycan_biosynthesis 2 49 0.1067 1
14 hsa04916_Melanogenesis 3 101 0.1076 1
15 hsa04620_Toll.like_receptor_signaling_pathway 3 102 0.11 1
16 hsa00983_Drug_metabolism_._other_enzymes 2 52 0.1177 1
17 hsa04150_mTOR_signaling_pathway 2 52 0.1177 1
18 hsa04340_Hedgehog_signaling_pathway 2 56 0.1329 1
19 hsa04623_Cytosolic_DNA.sensing_pathway 2 56 0.1329 1
20 hsa04722_Neurotrophin_signaling_pathway 3 127 0.1754 1
21 hsa04010_MAPK_signaling_pathway 5 268 0.1898 1
22 hsa04622_RIG.I.like_receptor_signaling_pathway 2 71 0.1928 1
23 hsa04514_Cell_adhesion_molecules_.CAMs. 3 136 0.2011 1
24 hsa04151_PI3K_AKT_signaling_pathway 6 351 0.21 1
25 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.2344 1
26 hsa03013_RNA_transport 3 152 0.2487 1
27 hsa04640_Hematopoietic_cell_lineage 2 88 0.2638 1
28 hsa04210_Apoptosis 2 89 0.268 1
29 hsa00230_Purine_metabolism 3 162 0.2793 1
30 hsa04141_Protein_processing_in_endoplasmic_reticulum 3 168 0.2978 1
31 hsa04660_T_cell_receptor_signaling_pathway 2 108 0.3473 1
32 hsa03040_Spliceosome 2 128 0.4276 1
33 hsa04360_Axon_guidance 2 130 0.4354 1
34 hsa04910_Insulin_signaling_pathway 2 138 0.4658 1
35 hsa04014_Ras_signaling_pathway 3 236 0.5031 1
36 hsa04145_Phagosome 2 156 0.5306 1
37 hsa04810_Regulation_of_actin_cytoskeleton 2 214 0.7012 1

Quest ID: 27bd2c2ae36e29ed7fcec8082753b21f