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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-17-5p AADAC 0.6 1.0E-5 -4.47 0 MirTarget -0.16 0.04206 NA
2 hsa-miR-17-5p ABCA1 0.6 1.0E-5 -1.41 0 MirTarget; TargetScan; miRNATAP -0.15 0 NA
3 hsa-miR-17-5p ABCD2 0.6 1.0E-5 -4.13 0 MirTarget -0.18 0.00554 NA
4 hsa-miR-17-5p ABHD2 0.6 1.0E-5 0.45 0.00053 TargetScan; miRNATAP -0.21 0 NA
5 hsa-miR-17-5p ACER2 0.6 1.0E-5 -1.35 0 TargetScan -0.49 0 NA
6 hsa-miR-17-5p ACOT2 0.6 1.0E-5 -0.5 0 miRNAWalker2 validate -0.23 0 NA
7 hsa-miR-17-5p ACSF2 0.6 1.0E-5 -0.26 0.05489 TargetScan -0.26 0 NA
8 hsa-miR-17-5p ACVR1B 0.6 1.0E-5 0.15 0.02139 TargetScan -0.12 0 NA
9 hsa-miR-17-5p ACVRL1 0.6 1.0E-5 -0.99 0 TargetScan -0.18 0 NA
10 hsa-miR-17-5p ADAM22 0.6 1.0E-5 -1.22 0 MirTarget; mirMAP -0.35 0 NA
11 hsa-miR-17-5p ADAMTS5 0.6 1.0E-5 -3.55 0 TargetScan -0.24 0 NA
12 hsa-miR-17-5p ADAMTSL2 0.6 1.0E-5 1.79 0 TargetScan -0.18 0 NA
13 hsa-miR-17-5p ADCY1 0.6 1.0E-5 -0.05 0.84149 mirMAP -0.51 0 NA
14 hsa-miR-17-5p ADCY9 0.6 1.0E-5 0.12 0.23839 mirMAP -0.3 0 NA
15 hsa-miR-17-5p AFF1 0.6 1.0E-5 -0.82 0 TargetScan -0.27 0 NA
16 hsa-miR-17-5p AFF4 0.6 1.0E-5 -0.28 0.00153 TargetScan; miRNATAP -0.19 0 NA
17 hsa-miR-17-5p AGFG2 0.6 1.0E-5 -0.32 2.0E-5 TargetScan; miRNATAP -0.17 0 NA
18 hsa-miR-17-5p AHNAK 0.6 1.0E-5 -1.77 0 TargetScan; miRNATAP -0.38 0 NA
19 hsa-miR-17-5p AJAP1 0.6 1.0E-5 -0.99 0 TargetScan -0.28 0 NA
20 hsa-miR-17-5p AKAP11 0.6 1.0E-5 -0.85 0 MirTarget; TargetScan -0.13 0 NA
21 hsa-miR-17-5p AKAP13 0.6 1.0E-5 -0.61 0 MirTarget; TargetScan; mirMAP; miRNATAP -0.11 0 NA
22 hsa-miR-17-5p AKAP9 0.6 1.0E-5 -0.15 0.13698 TargetScan -0.19 0 NA
23 hsa-miR-17-5p ALPK3 0.6 1.0E-5 -1.48 0 mirMAP -0.21 0 NA
24 hsa-miR-17-5p ALX4 0.6 1.0E-5 -3.22 0 TargetScan; miRNATAP -0.39 0 NA
25 hsa-miR-17-5p ANK2 0.6 1.0E-5 -2.51 0 MirTarget; miRNATAP -0.33 0 NA
26 hsa-miR-17-5p ANKRD12 0.6 1.0E-5 -0.64 0 MirTarget; TargetScan -0.12 0 NA
27 hsa-miR-17-5p ANKRD29 0.6 1.0E-5 -2.95 0 MirTarget; TargetScan -0.41 0 NA
28 hsa-miR-17-5p ANKRD50 0.6 1.0E-5 0.25 0.02231 MirTarget; TargetScan; miRNATAP -0.17 0 NA
29 hsa-miR-17-5p ANO6 0.6 1.0E-5 -1.5 0 MirTarget; TargetScan; miRNATAP -0.18 0 NA
30 hsa-miR-17-5p APBB2 0.6 1.0E-5 -0.39 0.0002 MirTarget; TargetScan; miRNATAP -0.34 0 NA
31 hsa-miR-17-5p AR 0.6 1.0E-5 -1 0.00094 mirMAP -1.2 0 23095762 miR 17 5p targets the p300/CBP associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells; Targeting of the 3'-untranslated region of PCAF mRNA by miR-17-5p caused translational suppression and RNA degradation and consequently modulation of AR transcriptional activity in PCa cells; Targeting of PCAF by miR-17-5p modulates AR transcriptional activity and cell growth in cultured PCa cells
32 hsa-miR-17-5p ARHGAP1 0.6 1.0E-5 0.21 1.0E-5 MirTarget; TargetScan; miRNATAP -0.11 0 NA
33 hsa-miR-17-5p ARHGAP12 0.6 1.0E-5 -0.58 0 TargetScan; miRNATAP -0.13 0 NA
34 hsa-miR-17-5p ARHGAP23 0.6 1.0E-5 -0.93 0 mirMAP -0.12 0 NA
35 hsa-miR-17-5p ARHGAP24 0.6 1.0E-5 -1.41 0 MirTarget -0.22 0 NA
36 hsa-miR-17-5p ARHGAP26 0.6 1.0E-5 -1.51 0 MirTarget; TargetScan; mirMAP; miRNATAP -0.13 2.0E-5 NA
37 hsa-miR-17-5p ARHGAP31 0.6 1.0E-5 -1.31 0 TargetScan -0.1 0.0001 NA
38 hsa-miR-17-5p ARHGEF3 0.6 1.0E-5 -0.04 0.65559 MirTarget; TargetScan; miRNATAP -0.19 0 NA
39 hsa-miR-17-5p ARHGEF38 0.6 1.0E-5 0.07 0.77513 mirMAP -0.73 0 NA
40 hsa-miR-17-5p ARID4A 0.6 1.0E-5 -0.86 0 MirTarget; TargetScan; miRNATAP -0.17 0 NA
41 hsa-miR-17-5p ARL1 0.6 1.0E-5 0.25 6.0E-5 TargetScan -0.1 0 NA
42 hsa-miR-17-5p ARL4A 0.6 1.0E-5 -1.62 0 TargetScan; miRNATAP -0.12 5.0E-5 NA
43 hsa-miR-17-5p ARSD 0.6 1.0E-5 0.28 0.00266 mirMAP -0.22 0 NA
44 hsa-miR-17-5p ASPA 0.6 1.0E-5 -3.96 0 mirMAP -0.56 0 NA
45 hsa-miR-17-5p ASXL2 0.6 1.0E-5 -0.86 0 TargetScan -0.11 0.00398 NA
46 hsa-miR-17-5p ASXL3 0.6 1.0E-5 -2.86 0 TargetScan -0.37 0 NA
47 hsa-miR-17-5p ATE1 0.6 1.0E-5 -0.72 0 MirTarget; TargetScan -0.16 0 NA
48 hsa-miR-17-5p ATG16L1 0.6 1.0E-5 0.51 0 MirTarget; TargetScan; miRNATAP -0.15 0 NA
49 hsa-miR-17-5p ATG2B 0.6 1.0E-5 -0.69 0 TargetScan -0.21 0 NA
50 hsa-miR-17-5p ATOH8 0.6 1.0E-5 -3.73 0 TargetScan -0.43 0 NA
51 hsa-miR-17-5p ATP1A2 0.6 1.0E-5 -5.48 0 MirTarget; TargetScan -1 0 NA
52 hsa-miR-17-5p ATRX 0.6 1.0E-5 -0.59 0 miRNAWalker2 validate; mirMAP -0.12 0 NA
53 hsa-miR-17-5p ATXN1 0.6 1.0E-5 -0.11 0.17245 TargetScan; miRNATAP -0.22 0 NA
54 hsa-miR-17-5p B3GALT2 0.6 1.0E-5 -1.54 0 MirTarget; TargetScan -0.19 0 NA
55 hsa-miR-17-5p BAZ2A 0.6 1.0E-5 -0.1 0.10091 miRNAWalker2 validate -0.11 0 NA
56 hsa-miR-17-5p BCAS1 0.6 1.0E-5 1.43 1.0E-5 mirMAP -1.08 0 NA
57 hsa-miR-17-5p BCL2 0.6 1.0E-5 -0.9 0 miRNAWalker2 validate; miRTarBase -0.42 0 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
58 hsa-miR-17-5p BCL6 0.6 1.0E-5 -1.26 0 TargetScan -0.16 0 NA
59 hsa-miR-17-5p BECN1 0.6 1.0E-5 0.13 0.02644 TargetScan -0.12 0 24755562; 25435430 miR 17 5p downregulation contributes to paclitaxel resistance of lung cancer cells through altering beclin1 expression; Moreover in this report we demonstrated that miR-17-5p directly binds to the 3'-UTR of beclin 1 gene one of the most important autophagy modulator; Overexpression of miR-17-5p into paclitaxel resistant lung cancer cells reduced beclin1 expression and a concordant decease in cellular autophagy; Our results indicated that paclitaxel resistance of lung cancer is associated with downregulation of miR-17-5p expression which might cause upregulation of BECN1 expression;Previously utilizing miRNA arrays we reported that downregulation of miR-17 is at least partly involved in the development of paclitaxel resistance in lung cancer cells by modulating Beclin-1 expression 1; Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
60 hsa-miR-17-5p BHLHE41 0.6 1.0E-5 -1.53 0 TargetScan; miRNATAP -0.16 0 NA
61 hsa-miR-17-5p BICC1 0.6 1.0E-5 -1.83 0 TargetScan -0.38 0 NA
62 hsa-miR-17-5p BLVRA 0.6 1.0E-5 0.57 0 miRNAWalker2 validate -0.19 0 NA
63 hsa-miR-17-5p BMP2K 0.6 1.0E-5 -0.61 0 TargetScan -0.16 0 NA
64 hsa-miR-17-5p BMPR2 0.6 1.0E-5 -0.62 0 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.17 0 NA
65 hsa-miR-17-5p BNC2 0.6 1.0E-5 -0.78 0 TargetScan; miRNATAP -0.44 0 NA
66 hsa-miR-17-5p BNIP3L 0.6 1.0E-5 -0.81 0 MirTarget; TargetScan -0.22 0 NA
67 hsa-miR-17-5p BTBD7 0.6 1.0E-5 -0.65 0 MirTarget; TargetScan; miRNATAP -0.14 0 NA
68 hsa-miR-17-5p BTG2 0.6 1.0E-5 -0.81 0 TargetScan -0.48 0 NA
69 hsa-miR-17-5p C10orf107 0.6 1.0E-5 -0.85 0.00043 TargetScan -0.49 0 NA
70 hsa-miR-17-5p C14orf28 0.6 1.0E-5 -0.85 0 TargetScan; miRNATAP -0.19 0 NA
71 hsa-miR-17-5p C16orf52 0.6 1.0E-5 -0.44 0 TargetScan; miRNATAP -0.11 0 NA
72 hsa-miR-17-5p C2CD2 0.6 1.0E-5 -1.52 0 MirTarget; TargetScan; miRNATAP -0.1 0.00029 NA
73 hsa-miR-17-5p C3orf70 0.6 1.0E-5 -0.82 0 TargetScan -0.11 0.00251 NA
74 hsa-miR-17-5p C6orf120 0.6 1.0E-5 -0.38 0 TargetScan; mirMAP -0.13 0 NA
75 hsa-miR-17-5p C9orf64 0.6 1.0E-5 0.27 0.00086 TargetScan -0.19 0 NA
76 hsa-miR-17-5p C9orf66 0.6 1.0E-5 -0.93 0 mirMAP -0.28 0 NA
77 hsa-miR-17-5p CA5B 0.6 1.0E-5 -0.81 0 mirMAP -0.18 0 NA
78 hsa-miR-17-5p CADM2 0.6 1.0E-5 -2.4 0 MirTarget; TargetScan; miRNATAP -0.49 0 NA
79 hsa-miR-17-5p CALN1 0.6 1.0E-5 -2.71 0 mirMAP -0.61 0 NA
80 hsa-miR-17-5p CAMK2N1 0.6 1.0E-5 0.27 0.07667 TargetScan; miRNATAP -0.37 0 NA
81 hsa-miR-17-5p CASC4 0.6 1.0E-5 -0.15 0.04292 MirTarget -0.2 0 NA
82 hsa-miR-17-5p CASP9 0.6 1.0E-5 0.06 0.30285 TargetScan -0.1 0 NA
83 hsa-miR-17-5p CBX7 0.6 1.0E-5 -1.71 0 mirMAP -0.36 0 NA
84 hsa-miR-17-5p CCBE1 0.6 1.0E-5 -2.57 0 mirMAP -0.29 0 NA
85 hsa-miR-17-5p CCDC103 0.6 1.0E-5 0.39 0.00267 mirMAP -0.29 0 NA
86 hsa-miR-17-5p CCDC125 0.6 1.0E-5 0.56 0 mirMAP -0.3 0 NA
87 hsa-miR-17-5p CCDC144A 0.6 1.0E-5 -1.82 0 TargetScan -0.16 0.00745 NA
88 hsa-miR-17-5p CCND1 0.6 1.0E-5 0.79 0 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.24 0 26431674 Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene
89 hsa-miR-17-5p CCND2 0.6 1.0E-5 -1.32 0 miRNAWalker2 validate; miRTarBase; TargetScan; miRNATAP -0.22 0 NA
90 hsa-miR-17-5p CCNG2 0.6 1.0E-5 -0.15 0.14084 MirTarget; TargetScan; miRNATAP -0.26 0 NA
91 hsa-miR-17-5p CD69 0.6 1.0E-5 -0.8 0 TargetScan; miRNATAP -0.17 0.00011 NA
92 hsa-miR-17-5p CDHR3 0.6 1.0E-5 -0.46 0.04587 mirMAP -0.33 0 NA
93 hsa-miR-17-5p CDKN1A 0.6 1.0E-5 -0.25 0.02507 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.16 0 26482648; 24989082 The low expressions of miR-17 and miR-92 families can maintain cisplatin resistance through the regulation of CDKN1A and RAD21;According to PicTar and Miranda algorithms which predicted CDKN1A p21 as a putative target of miR-17 a luciferase assay was performed and revealed that miR-17 directly targets the 3'-UTR of p21 mRNA
94 hsa-miR-17-5p CELF2 0.6 1.0E-5 -2.12 0 TargetScan -0.13 0.0004 NA
95 hsa-miR-17-5p CEP120 0.6 1.0E-5 -0.64 0 MirTarget; TargetScan; miRNATAP -0.19 0 NA
96 hsa-miR-17-5p CERCAM 0.6 1.0E-5 1.06 0 MirTarget; TargetScan -0.17 0 NA
97 hsa-miR-17-5p CHD9 0.6 1.0E-5 -1.21 0 MirTarget; TargetScan; miRNATAP -0.16 0 NA
98 hsa-miR-17-5p CHIC1 0.6 1.0E-5 -0.56 0 TargetScan -0.25 0 NA
99 hsa-miR-17-5p CHST7 0.6 1.0E-5 -1.02 0 TargetScan -0.13 0 NA
100 hsa-miR-17-5p CLIC6 0.6 1.0E-5 -0.71 0.0354 mirMAP -0.69 0 NA
101 hsa-miR-17-5p CNN1 0.6 1.0E-5 -3.24 0 TargetScan -0.48 0 NA
102 hsa-miR-17-5p COL1A1 0.6 1.0E-5 2.57 0 mirMAP -0.28 0 NA
103 hsa-miR-17-5p COL8A2 0.6 1.0E-5 0.33 0.02755 mirMAP -0.35 0 NA
104 hsa-miR-17-5p CORO2B 0.6 1.0E-5 -2.6 0 MirTarget; TargetScan; miRNATAP -0.44 0 NA
105 hsa-miR-17-5p CPD 0.6 1.0E-5 -0.24 0.02078 mirMAP -0.22 0 NA
106 hsa-miR-17-5p CPE 0.6 1.0E-5 -1.23 0 miRNAWalker2 validate -0.43 0 NA
107 hsa-miR-17-5p CPEB3 0.6 1.0E-5 -0.8 0 TargetScan; miRNATAP -0.27 0 NA
108 hsa-miR-17-5p CPEB4 0.6 1.0E-5 -0.46 2.0E-5 mirMAP -0.29 0 NA
109 hsa-miR-17-5p CPS1 0.6 1.0E-5 -2.23 0 miRNAWalker2 validate -0.2 7.0E-5 NA
110 hsa-miR-17-5p CPT1A 0.6 1.0E-5 -0.13 0.20253 mirMAP -0.12 1.0E-5 NA
111 hsa-miR-17-5p CRIM1 0.6 1.0E-5 -2.03 0 MirTarget; TargetScan; miRNATAP -0.26 0 NA
112 hsa-miR-17-5p CROT 0.6 1.0E-5 0.04 0.77707 MirTarget -0.46 0 NA
113 hsa-miR-17-5p CRY2 0.6 1.0E-5 -1.2 0 MirTarget; TargetScan; miRNATAP -0.29 0 NA
114 hsa-miR-17-5p CRYBG3 0.6 1.0E-5 -2.3 0 MirTarget; TargetScan; miRNATAP -0.18 2.0E-5 NA
115 hsa-miR-17-5p CSF1 0.6 1.0E-5 -1.09 0 TargetScan; miRNATAP -0.17 0 NA
116 hsa-miR-17-5p CSGALNACT1 0.6 1.0E-5 -1.07 0 MirTarget; TargetScan -0.12 3.0E-5 NA
117 hsa-miR-17-5p CSNK1A1 0.6 1.0E-5 0.19 0.00089 TargetScan -0.14 0 NA
118 hsa-miR-17-5p CSRNP3 0.6 1.0E-5 -3.02 0 MirTarget; TargetScan; miRNATAP -0.35 0 NA
119 hsa-miR-17-5p CTDSPL 0.6 1.0E-5 -0.59 0 TargetScan; mirMAP -0.14 0 NA
120 hsa-miR-17-5p CTSK 0.6 1.0E-5 -0.21 0.15345 MirTarget -0.36 0 NA
121 hsa-miR-17-5p CXCL14 0.6 1.0E-5 -1.98 0 TargetScan -0.61 0 NA
122 hsa-miR-17-5p CXorf23 0.6 1.0E-5 -0.33 0 mirMAP -0.13 0 NA
123 hsa-miR-17-5p CXorf36 0.6 1.0E-5 -2.1 0 mirMAP -0.36 0 NA
124 hsa-miR-17-5p CYBRD1 0.6 1.0E-5 -1.65 0 MirTarget; TargetScan -0.6 0 NA
125 hsa-miR-17-5p CYP2U1 0.6 1.0E-5 -1.62 0 MirTarget; TargetScan -0.18 0 NA
126 hsa-miR-17-5p DAB1 0.6 1.0E-5 -0.43 0.06301 TargetScan -0.25 2.0E-5 NA
127 hsa-miR-17-5p DAB2 0.6 1.0E-5 -1.07 0 MirTarget; TargetScan; miRNATAP -0.24 0 NA
128 hsa-miR-17-5p DAZAP2 0.6 1.0E-5 0.05 0.32954 MirTarget; TargetScan; miRNATAP -0.12 0 NA
129 hsa-miR-17-5p DCUN1D3 0.6 1.0E-5 -1.06 0 MirTarget; TargetScan -0.14 0 NA
130 hsa-miR-17-5p DENND5B 0.6 1.0E-5 -1.14 0 MirTarget; TargetScan; miRNATAP -0.31 0 NA
131 hsa-miR-17-5p DICER1 0.6 1.0E-5 -0.49 0 mirMAP -0.14 0 21935572 microRNA 18a a member of the oncogenic miR 17 92 cluster targets Dicer and suppresses cell proliferation in bladder cancer T24 cells
132 hsa-miR-17-5p DIXDC1 0.6 1.0E-5 -1.64 0 mirMAP -0.32 0 NA
133 hsa-miR-17-5p DLG2 0.6 1.0E-5 -1.71 0 mirMAP -0.4 0 NA
134 hsa-miR-17-5p DNAJB9 0.6 1.0E-5 -0.16 0.02865 TargetScan; miRNATAP -0.11 0 NA
135 hsa-miR-17-5p DNAJC16 0.6 1.0E-5 -0.02 0.7897 MirTarget; TargetScan -0.15 0 NA
136 hsa-miR-17-5p DNAJC27 0.6 1.0E-5 -0.81 0 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.12 0 NA
137 hsa-miR-17-5p DNAJC28 0.6 1.0E-5 -0.42 0 TargetScan -0.16 0 NA
138 hsa-miR-17-5p DNAL1 0.6 1.0E-5 -0.21 0.01589 TargetScan -0.28 0 NA
139 hsa-miR-17-5p DNMBP 0.6 1.0E-5 -0.67 0 miRNAWalker2 validate -0.38 0 NA
140 hsa-miR-17-5p DOCK4 0.6 1.0E-5 -0.96 0 MirTarget; TargetScan -0.13 0 NA
141 hsa-miR-17-5p DOK6 0.6 1.0E-5 -0.41 0.00604 TargetScan -0.35 0 NA
142 hsa-miR-17-5p DPP8 0.6 1.0E-5 -0.8 0 mirMAP -0.18 0 NA
143 hsa-miR-17-5p DPYD 0.6 1.0E-5 -1.53 0 MirTarget -0.23 0 NA
144 hsa-miR-17-5p DRD1 0.6 1.0E-5 -2.11 0 TargetScan -0.41 0 NA
145 hsa-miR-17-5p DST 0.6 1.0E-5 -2.66 0 mirMAP -0.25 0 NA
146 hsa-miR-17-5p ECE1 0.6 1.0E-5 -0.43 0 mirMAP -0.2 0 NA
147 hsa-miR-17-5p EDA2R 0.6 1.0E-5 -1.34 0 MirTarget; TargetScan -0.44 0 NA
148 hsa-miR-17-5p EEA1 0.6 1.0E-5 -0.92 0 MirTarget; TargetScan; miRNATAP -0.17 0 NA
149 hsa-miR-17-5p EEF2K 0.6 1.0E-5 -0.49 0 mirMAP -0.13 0 NA
150 hsa-miR-17-5p EFCAB2 0.6 1.0E-5 -0.08 0.43842 mirMAP -0.14 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 103 1518 3.509e-13 1.633e-09
2 POSITIVE REGULATION OF CATALYTIC ACTIVITY 101 1518 2.028e-12 3.826e-09
3 POSITIVE REGULATION OF MOLECULAR FUNCTION 113 1791 2.467e-12 3.826e-09
4 RESPONSE TO ENDOGENOUS STIMULUS 96 1450 1.04e-11 1.21e-08
5 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 110 1784 2.132e-11 1.984e-08
6 CELL DEVELOPMENT 93 1426 5.228e-11 4.055e-08
7 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 108 1805 1.992e-10 1.159e-07
8 POSITIVE REGULATION OF GENE EXPRESSION 105 1733 1.839e-10 1.159e-07
9 CARDIOVASCULAR SYSTEM DEVELOPMENT 60 788 6.677e-10 3.107e-07
10 CIRCULATORY SYSTEM DEVELOPMENT 60 788 6.677e-10 3.107e-07
11 REGULATION OF CELLULAR COMPONENT MOVEMENT 59 771 7.735e-10 3.272e-07
12 EPITHELIUM DEVELOPMENT 67 945 1.255e-09 4.172e-07
13 REGULATION OF CELL DIFFERENTIATION 92 1492 1.24e-09 4.172e-07
14 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 70 1008 1.25e-09 4.172e-07
15 REGULATION OF GTPASE ACTIVITY 53 673 2.198e-09 6.817e-07
16 POSITIVE REGULATION OF HYDROLASE ACTIVITY 64 905 3.354e-09 9.181e-07
17 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 106 1848 3.198e-09 9.181e-07
18 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 30 278 8.184e-09 2.116e-06
19 NEUROGENESIS 85 1402 1.264e-08 3.097e-06
20 HEART DEVELOPMENT 40 466 2.144e-08 4.751e-06
21 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 54 740 2.143e-08 4.751e-06
22 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 95 1656 2.417e-08 5.111e-06
23 EPITHELIAL CELL DEVELOPMENT 23 186 3.713e-08 7.451e-06
24 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 72 1142 4.004e-08 7.451e-06
25 EPITHELIAL CELL DIFFERENTIATION 41 495 3.869e-08 7.451e-06
26 REGULATION OF HYDROLASE ACTIVITY 80 1327 4.559e-08 8.159e-06
27 INTRACELLULAR SIGNAL TRANSDUCTION 90 1572 6.565e-08 1.131e-05
28 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 94 1672 7.54e-08 1.253e-05
29 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 55 799 1.114e-07 1.787e-05
30 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 1004 1.635e-07 2.535e-05
31 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 38 465 1.731e-07 2.598e-05
32 OSSIFICATION 26 251 1.836e-07 2.67e-05
33 NEGATIVE REGULATION OF GENE EXPRESSION 85 1493 2.038e-07 2.843e-05
34 REGULATION OF SYSTEM PROCESS 40 507 2.078e-07 2.843e-05
35 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 49 689 2.156e-07 2.867e-05
36 TUBE DEVELOPMENT 42 552 2.752e-07 3.553e-05
37 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 40 513 2.825e-07 3.553e-05
38 POSITIVE REGULATION OF LOCOMOTION 35 420 3.357e-07 4.11e-05
39 RESPONSE TO HORMONE 58 893 3.498e-07 4.173e-05
40 REGULATION OF PHOSPHORUS METABOLIC PROCESS 89 1618 4.572e-07 5.319e-05
41 RESPONSE TO OXYGEN CONTAINING COMPOUND 79 1381 4.784e-07 5.429e-05
42 UROGENITAL SYSTEM DEVELOPMENT 28 299 5.065e-07 5.612e-05
43 ORGAN MORPHOGENESIS 55 841 5.755e-07 6.228e-05
44 POSITIVE REGULATION OF CELL DIFFERENTIATION 54 823 6.618e-07 6.999e-05
45 REGULATION OF PROTEIN MODIFICATION PROCESS 92 1710 7.505e-07 7.76e-05
46 NEURON DIFFERENTIATION 56 874 8.64e-07 8.739e-05
47 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 78 1395 1.378e-06 0.0001365
48 CELL DEATH 61 1001 1.456e-06 0.0001412
49 ACTIN FILAMENT BASED PROCESS 35 450 1.668e-06 0.0001584
50 CHEMICAL HOMEOSTASIS 55 874 1.884e-06 0.0001719
51 ACTION POTENTIAL 14 94 1.879e-06 0.0001719
52 TISSUE MORPHOGENESIS 39 533 1.931e-06 0.0001728
53 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 62 1036 2.152e-06 0.0001855
54 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 62 1036 2.152e-06 0.0001855
55 REGULATION OF METAL ION TRANSPORT 28 325 2.649e-06 0.0002241
56 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 82 1517 2.713e-06 0.0002254
57 BLOOD VESSEL MORPHOGENESIS 30 364 2.903e-06 0.0002369
58 BONE DEVELOPMENT 18 156 3.07e-06 0.0002463
59 VENOUS BLOOD VESSEL DEVELOPMENT 6 15 4.328e-06 0.0003414
60 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 80 1492 4.923e-06 0.0003695
61 RHYTHMIC PROCESS 26 298 4.772e-06 0.0003695
62 POSITIVE REGULATION OF CELL DEVELOPMENT 35 472 4.852e-06 0.0003695
63 REGULATION OF OSSIFICATION 19 178 5.251e-06 0.0003878
64 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 22 229 5.537e-06 0.0004004
65 SKELETAL SYSTEM DEVELOPMENT 34 455 5.615e-06 0.0004004
66 REGULATION OF CIRCADIAN RHYTHM 14 103 5.679e-06 0.0004004
67 RESPONSE TO STEROID HORMONE 36 497 6.013e-06 0.0004176
68 CELLULAR RESPONSE TO LIPID 34 457 6.169e-06 0.0004221
69 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 16 133 6.276e-06 0.0004232
70 NEGATIVE REGULATION OF CELL COMMUNICATION 67 1192 6.868e-06 0.0004565
71 REGULATION OF TRANSPORT 92 1804 6.983e-06 0.0004576
72 HOMEOSTATIC PROCESS 73 1337 7.158e-06 0.0004626
73 RESPONSE TO ORGANIC CYCLIC COMPOUND 55 917 7.79e-06 0.0004965
74 NEGATIVE REGULATION OF CELL DIFFERENTIATION 41 609 8.242e-06 0.0005183
75 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 19 184 8.516e-06 0.0005283
76 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 8 34 9.79e-06 0.0005916
77 REGULATION OF ION TRANSPORT 40 592 9.763e-06 0.0005916
78 RESPONSE TO NITROGEN COMPOUND 52 859 1.078e-05 0.000627
79 CELLULAR RESPONSE TO HORMONE STIMULUS 38 552 1.072e-05 0.000627
80 VASCULATURE DEVELOPMENT 34 469 1.069e-05 0.000627
81 REGULATION OF CELL SUBSTRATE ADHESION 18 173 1.317e-05 0.0007566
82 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 207 1.345e-05 0.0007571
83 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 19 190 1.351e-05 0.0007571
84 RESPONSE TO GROWTH FACTOR 34 475 1.395e-05 0.0007728
85 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 49 801 1.481e-05 0.0008105
86 DEVELOPMENTAL MATURATION 19 193 1.687e-05 0.000913
87 HEART PROCESS 12 85 1.776e-05 0.0009499
88 CARDIAC MUSCLE CELL ACTION POTENTIAL 8 37 1.911e-05 0.001011
89 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 17 162 2.035e-05 0.001064
90 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 58 1021 2.173e-05 0.001123
91 POSITIVE REGULATION OF CELL COMMUNICATION 79 1532 2.289e-05 0.00117
92 REGULATION OF KINASE ACTIVITY 47 776 2.844e-05 0.001423
93 NEGATIVE REGULATION OF GROWTH 21 236 2.874e-05 0.001423
94 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 20 218 2.862e-05 0.001423
95 CARDIAC MUSCLE CELL CONTRACTION 7 29 2.98e-05 0.001451
96 SENSORY ORGAN DEVELOPMENT 34 493 2.994e-05 0.001451
97 SODIUM ION TRANSMEMBRANE TRANSPORT 12 90 3.193e-05 0.001501
98 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 68 1275 3.174e-05 0.001501
99 REGULATION OF CELL MATRIX ADHESION 12 90 3.193e-05 0.001501
100 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 62 1135 3.616e-05 0.001683
101 CIRCADIAN RHYTHM 15 137 3.76e-05 0.00172
102 CELLULAR COMPONENT MORPHOGENESIS 52 900 3.77e-05 0.00172
103 REGULATION OF CELL DEVELOPMENT 49 836 4.431e-05 0.002001
104 POSITIVE REGULATION OF KINASE ACTIVITY 33 482 4.509e-05 0.002017
105 LENS DEVELOPMENT IN CAMERA TYPE EYE 10 66 4.759e-05 0.002109
106 STEROID HORMONE MEDIATED SIGNALING PATHWAY 14 125 5.271e-05 0.002314
107 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 39 616 5.339e-05 0.002322
108 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 5 14 5.438e-05 0.002343
109 SINGLE ORGANISM BEHAVIOR 28 384 5.727e-05 0.002422
110 REGULATION OF EPITHELIAL CELL PROLIFERATION 23 285 5.684e-05 0.002422
111 REGULATION OF TRANSMEMBRANE TRANSPORT 30 426 5.966e-05 0.002501
112 NEURON DEVELOPMENT 42 687 6.148e-05 0.002553
113 EMBRYO DEVELOPMENT 51 894 6.2e-05 0.002553
114 CIRCULATORY SYSTEM PROCESS 27 366 6.351e-05 0.002592
115 EAR DEVELOPMENT 18 195 6.547e-05 0.002649
116 PROTEIN PHOSPHORYLATION 53 944 6.735e-05 0.002678
117 SODIUM ION TRANSPORT 15 144 6.714e-05 0.002678
118 RESPONSE TO DRUG 30 431 7.369e-05 0.002896
119 BEHAVIOR 34 516 7.407e-05 0.002896
120 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 12 98 7.49e-05 0.002904
121 RESPONSE TO OXYGEN LEVELS 24 311 8e-05 0.003076
122 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 34 8.928e-05 0.003405
123 DIGESTIVE SYSTEM DEVELOPMENT 15 148 9.187e-05 0.003475
124 POSITIVE REGULATION OF CATABOLIC PROCESS 28 395 9.32e-05 0.003497
125 REGULATION OF CELL DEATH 74 1472 9.553e-05 0.003544
126 REGULATION OF BLOOD CIRCULATION 23 295 9.598e-05 0.003544
127 SKELETAL SYSTEM MORPHOGENESIS 18 201 9.682e-05 0.003547
128 CELLULAR RESPONSE TO NITROGEN COMPOUND 33 505 0.0001102 0.003997
129 RENAL SYSTEM PROCESS 12 102 0.0001108 0.003997
130 REGULATION OF ARF PROTEIN SIGNAL TRANSDUCTION 5 16 0.0001124 0.004024
131 LENS FIBER CELL DIFFERENTIATION 6 25 0.0001162 0.004097
132 MORPHOGENESIS OF AN EPITHELIUM 28 400 0.0001154 0.004097
133 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 69 1360 0.0001274 0.004458
134 NEGATIVE REGULATION OF CELL GROWTH 16 170 0.0001308 0.004543
135 REGULATION OF TRANSFERASE ACTIVITY 52 946 0.000134 0.004586
136 REGULATION OF LIPID METABOLIC PROCESS 22 282 0.000134 0.004586
137 CELL CYCLE ARREST 15 154 0.0001438 0.004884
138 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 13 121 0.000148 0.004961
139 EMBRYONIC ORGAN DEVELOPMENT 28 406 0.0001482 0.004961
140 ENDOTHELIUM DEVELOPMENT 11 90 0.0001507 0.005007
141 REGULATION OF NEURON APOPTOTIC PROCESS 17 192 0.000172 0.005676
142 MULTICELLULAR ORGANISMAL SIGNALING 13 123 0.0001747 0.005724
143 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 52 957 0.000178 0.005742
144 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 60 1152 0.0001796 0.005742
145 REGULATION OF SODIUM ION TRANSPORT 10 77 0.00018 0.005742
146 MUSCLE STRUCTURE DEVELOPMENT 29 432 0.0001802 0.005742
147 CELLULAR RESPONSE TO ACID CHEMICAL 16 175 0.0001833 0.005775
148 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 8 50 0.0001837 0.005775
149 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 7 38 0.0001873 0.005809
150 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 53 983 0.0001868 0.005809
151 APOPTOTIC SIGNALING PATHWAY 22 289 0.0001902 0.005851
152 RESPONSE TO LIPID 49 888 0.0001911 0.005851
153 CONNECTIVE TISSUE DEVELOPMENT 17 194 0.0001948 0.005924
154 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 7 39 0.0002219 0.006676
155 OSTEOBLAST DIFFERENTIATION 13 126 0.0002224 0.006676
156 POSITIVE REGULATION OF RESPONSE TO STIMULUS 90 1929 0.0002291 0.006832
157 LOCOMOTION 58 1114 0.0002326 0.006893
158 NEGATIVE REGULATION OF ION TRANSPORT 13 127 0.0002406 0.007085
159 REGULATION OF VASOCONSTRICTION 9 66 0.0002589 0.007576
160 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 7 40 0.0002616 0.007607
161 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 337 0.00027 0.007768
162 REGULATION OF OSTEOBLAST DIFFERENTIATION 12 112 0.0002705 0.007768
163 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 8 53 0.0002785 0.007871
164 RESPONSE TO ABIOTIC STIMULUS 54 1024 0.0002808 0.007871
165 CELL JUNCTION ASSEMBLY 13 129 0.0002808 0.007871
166 ION HOMEOSTASIS 35 576 0.0002792 0.007871
167 POSITIVE REGULATION OF NUCLEAR TRANSCRIBED MRNA POLY A TAIL SHORTENING 4 11 0.0002969 0.008031
168 LYMPHANGIOGENESIS 4 11 0.0002969 0.008031
169 REGULATION OF NUCLEAR TRANSCRIBED MRNA POLY A TAIL SHORTENING 4 11 0.0002969 0.008031
170 NEURON PROJECTION MORPHOGENESIS 27 402 0.0002952 0.008031
171 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 9 67 0.0002906 0.008031
172 REGULATION OF STEM CELL DIFFERENTIATION 12 113 0.0002939 0.008031
173 REGULATION OF MEMBRANE DEPOLARIZATION 7 41 0.0003067 0.00822
174 EMBRYONIC ORGAN MORPHOGENESIS 21 279 0.0003074 0.00822
175 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 11 98 0.0003216 0.008551
176 REGULATION OF CELL JUNCTION ASSEMBLY 9 68 0.0003255 0.008606
177 REGULATION OF EPITHELIAL CELL MIGRATION 15 166 0.0003275 0.00861
178 NEGATIVE REGULATION OF CELL MATRIX ADHESION 6 30 0.0003396 0.008828
179 BIOLOGICAL ADHESION 54 1032 0.0003389 0.008828
180 CELL JUNCTION ORGANIZATION 16 185 0.0003448 0.008912
181 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 11 99 0.0003515 0.008967
182 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 11 99 0.0003515 0.008967
183 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 17 204 0.0003527 0.008967
184 EMBRYONIC MORPHOGENESIS 33 539 0.0003618 0.009052
185 TUBE MORPHOGENESIS 23 323 0.0003601 0.009052
186 LYMPH VESSEL DEVELOPMENT 5 20 0.0003585 0.009052
187 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 15 168 0.0003725 0.009268
188 REGULATION OF GROWTH 37 633 0.0003982 0.009857
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 100 1737 8.058e-09 7.486e-06
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 45 629 5.806e-07 0.0002697
3 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 70 1199 1.111e-06 0.0003441
4 MOLECULAR FUNCTION REGULATOR 76 1353 1.609e-06 0.0003737
5 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 10 48 2.488e-06 0.0003878
6 STEROID HORMONE RECEPTOR ACTIVITY 11 59 2.505e-06 0.0003878
7 PROTEIN HOMODIMERIZATION ACTIVITY 47 722 4.437e-06 0.0005889
8 REGULATORY REGION NUCLEIC ACID BINDING 50 818 1.236e-05 0.001092
9 KINASE ACTIVITY 51 842 1.293e-05 0.001092
10 ENZYME ACTIVATOR ACTIVITY 34 471 1.169e-05 0.001092
11 GROWTH FACTOR BINDING 15 123 1.029e-05 0.001092
12 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 25 303 1.89e-05 0.001361
13 TRANSCRIPTION FACTOR BINDING 36 524 1.905e-05 0.001361
14 PROTEIN KINASE ACTIVITY 41 640 2.634e-05 0.001748
15 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 6 20 2.919e-05 0.001808
16 KINASE BINDING 39 606 3.742e-05 0.002173
17 CALCIUM ION BINDING 43 697 4.08e-05 0.00223
18 RECEPTOR BINDING 75 1476 6.066e-05 0.003131
19 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 25 328 6.986e-05 0.003416
20 ACTIVATING TRANSCRIPTION FACTOR BINDING 9 57 8.143e-05 0.003782
21 SMAD BINDING 10 72 0.0001017 0.004497
22 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 19 228 0.0001623 0.006852
23 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 24 329 0.0001889 0.007632
24 SEQUENCE SPECIFIC DNA BINDING 55 1037 0.0002139 0.008279
25 HORMONE BINDING 9 65 0.0002301 0.008339
26 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 53 992 0.0002334 0.008339
27 GTPASE BINDING 22 295 0.0002539 0.008737
28 PROTEIN DIMERIZATION ACTIVITY 59 1149 0.0002937 0.009159
29 PROTEIN SERINE THREONINE KINASE ACTIVITY 29 445 0.0002958 0.009159
30 MACROMOLECULAR COMPLEX BINDING 69 1399 0.0002882 0.009159
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PART 71 1265 3.76e-06 0.0009065
2 CELL JUNCTION 67 1151 2.126e-06 0.0009065
3 CELL PROJECTION 92 1786 4.657e-06 0.0009065
4 INTRINSIC COMPONENT OF PLASMA MEMBRANE 85 1649 1.097e-05 0.001068
5 NEURON PROJECTION 56 942 8.325e-06 0.001068
6 MEMBRANE REGION 64 1134 9.835e-06 0.001068
7 VOLTAGE GATED SODIUM CHANNEL COMPLEX 5 14 5.438e-05 0.004537
8 T TUBULE 8 45 8.499e-05 0.004977
9 PLASMA MEMBRANE REGION 52 929 8.522e-05 0.004977
10 CELL LEADING EDGE 26 350 7.704e-05 0.004977
11 PROTEIN KINASE COMPLEX 11 90 0.0001507 0.006884
12 SODIUM CHANNEL COMPLEX 5 17 0.0001551 0.006884
13 ANCHORING JUNCTION 32 489 0.0001359 0.006884
14 SOMATODENDRITIC COMPARTMENT 39 650 0.000165 0.006884
15 MEMBRANE MICRODOMAIN 22 288 0.0001811 0.007049
16 POSTSYNAPSE 26 378 0.0002632 0.00854
17 CELL SUBSTRATE JUNCTION 27 398 0.0002519 0.00854
18 SYNAPSE 43 754 0.0002349 0.00854

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 FoxO_signaling_pathway_hsa04068 16 132 5.688e-06 0.0002958
2 p53_signaling_pathway_hsa04115 10 68 6.189e-05 0.001609
3 Gap_junction_hsa04540 11 88 0.0001228 0.002129
4 Endocytosis_hsa04144 19 244 0.0003846 0.004999
5 Hedgehog_signaling_pathway_hsa04340 7 47 0.0007259 0.007549
6 PI3K_Akt_signaling_pathway_hsa04151 23 352 0.001166 0.01011
7 TGF_beta_signaling_pathway_hsa04350 9 84 0.001541 0.01145
8 Focal_adhesion_hsa04510 15 199 0.002101 0.01366
9 Autophagy_animal_hsa04140 11 128 0.002936 0.01696
10 Hippo_signaling_pathway_hsa04390 12 154 0.004327 0.0225
11 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 11 139 0.005495 0.02597
12 Calcium_signaling_pathway_hsa04020 13 182 0.006332 0.02744
13 Oocyte_meiosis_hsa04114 10 124 0.006965 0.02786
14 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.01349 0.04569
15 Apelin_signaling_pathway_hsa04371 10 137 0.01354 0.04569
16 HIF_1_signaling_pathway_hsa04066 8 100 0.01568 0.04569
17 MAPK_signaling_pathway_hsa04010 17 295 0.0158 0.04569
18 AMPK_signaling_pathway_hsa04152 9 121 0.01666 0.04569
19 Rap1_signaling_pathway_hsa04015 13 206 0.0167 0.04569
20 Ras_signaling_pathway_hsa04014 14 232 0.01894 0.04925
21 Apoptosis_multiple_species_hsa04215 4 33 0.021 0.05201
22 Tight_junction_hsa04530 11 170 0.02242 0.053
23 Cellular_senescence_hsa04218 10 160 0.03516 0.07949
24 Sphingolipid_signaling_pathway_hsa04071 8 118 0.03756 0.08138
25 ECM_receptor_interaction_hsa04512 6 82 0.04937 0.1027
26 Jak_STAT_signaling_pathway_hsa04630 9 162 0.08012 0.1602
27 Autophagy_other_hsa04136 3 32 0.08338 0.1606
28 Phospholipase_D_signaling_pathway_hsa04072 8 146 0.1012 0.1879
29 mTOR_signaling_pathway_hsa04150 8 151 0.1166 0.2091
30 Mitophagy_animal_hsa04137 4 65 0.1581 0.2741
31 Cytokine_cytokine_receptor_interaction_hsa04060 12 270 0.1659 0.2784
32 Wnt_signaling_pathway_hsa04310 7 146 0.194 0.3152
33 Adherens_junction_hsa04520 4 72 0.2033 0.3204
34 Cell_cycle_hsa04110 6 124 0.2126 0.3251
35 TNF_signaling_pathway_hsa04668 5 108 0.2705 0.3974
36 cGMP_PKG_signaling_pathway_hsa04022 7 163 0.2751 0.3974
37 Apoptosis_hsa04210 6 138 0.2879 0.4035
38 ErbB_signaling_pathway_hsa04012 4 85 0.2949 0.4035
39 cAMP_signaling_pathway_hsa04024 8 198 0.3101 0.4134
40 Phosphatidylinositol_signaling_system_hsa04070 4 99 0.3978 0.5171
41 Neuroactive_ligand_receptor_interaction_hsa04080 10 278 0.4098 0.5197
42 ABC_transporters_hsa02010 2 45 0.4292 0.5314
43 Peroxisome_hsa04146 3 83 0.5048 0.6104
44 Phagosome_hsa04145 5 152 0.5468 0.6462
45 VEGF_signaling_pathway_hsa04370 2 59 0.5725 0.6615
46 NF_kappa_B_signaling_pathway_hsa04064 3 95 0.5964 0.6742
47 Lysosome_hsa04142 3 123 0.7636 0.8215
48 Necroptosis_hsa04217 4 164 0.7801 0.8215
49 Regulation_of_actin_cytoskeleton_hsa04810 5 208 0.8057 0.8215
50 Cell_adhesion_molecules_.CAMs._hsa04514 2 145 0.9506 0.9506

Quest ID: 2f762a90c1d56eb1489d3952be15a528