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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-130a-3p ABHD2 2.02 0 -0.37 0.12248 mirMAP -0.21 0 NA
2 hsa-miR-130a-3p ACSL1 2.02 0 -0 0.993 MirTarget; miRNATAP -0.17 6.0E-5 NA
3 hsa-miR-130a-3p ACVR1 2.02 0 -0.44 0.01143 miRNAWalker2 validate; MirTarget; miRNATAP -0.11 0.00012 NA
4 hsa-miR-130a-3p ACVR2A 2.02 0 -0.44 0.02646 miRNATAP -0.16 0 NA
5 hsa-miR-130a-3p ADCY2 2.02 0 -3.87 0 miRNATAP -0.35 0.00023 NA
6 hsa-miR-130a-3p AFF1 2.02 0 -0.53 0.00163 MirTarget -0.14 0 NA
7 hsa-miR-130a-3p AKAP1 2.02 0 -0.34 0.0302 miRNATAP -0.13 0 NA
8 hsa-miR-130a-3p AKAP7 2.02 0 -1.26 1.0E-5 miRNATAP -0.16 0.0004 NA
9 hsa-miR-130a-3p ALDH5A1 2.02 0 0.21 0.50454 mirMAP -0.11 0.03507 NA
10 hsa-miR-130a-3p ALPK3 2.02 0 -1.02 0.00049 mirMAP -0.32 0 NA
11 hsa-miR-130a-3p ANKRD12 2.02 0 -0.64 0.00012 MirTarget; miRNATAP -0.11 7.0E-5 NA
12 hsa-miR-130a-3p ANXA11 2.02 0 -0.43 0.01849 mirMAP -0.15 0 NA
13 hsa-miR-130a-3p APCDD1 2.02 0 -1.6 0 MirTarget -0.14 0.01198 NA
14 hsa-miR-130a-3p AR 2.02 0 -3.3 0 mirMAP; miRNATAP -0.61 0 NA
15 hsa-miR-130a-3p ARHGAP1 2.02 0 -0.88 0 MirTarget; miRNATAP -0.16 0 NA
16 hsa-miR-130a-3p ARHGAP26 2.02 0 -0.72 0.00357 mirMAP -0.11 0.00418 NA
17 hsa-miR-130a-3p ARHGEF12 2.02 0 -0.64 4.0E-5 MirTarget; miRNATAP -0.17 0 NA
18 hsa-miR-130a-3p ARRDC3 2.02 0 -0.71 0.00062 miRNATAP -0.11 0.00051 NA
19 hsa-miR-130a-3p ASPA 2.02 0 -4.76 0 mirMAP -0.6 0 NA
20 hsa-miR-130a-3p ASXL2 2.02 0 -0.51 0.09339 MirTarget; miRNATAP -0.12 0.01476 NA
21 hsa-miR-130a-3p ASXL3 2.02 0 -3.34 0 mirMAP -0.32 0.00022 NA
22 hsa-miR-130a-3p ATXN1 2.02 0 -1.51 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.21 0 NA
23 hsa-miR-130a-3p ATXN7L1 2.02 0 -0.62 4.0E-5 miRNATAP -0.1 1.0E-5 NA
24 hsa-miR-130a-3p BHLHE41 2.02 0 -0.07 0.8646 MirTarget; miRNATAP -0.35 0 NA
25 hsa-miR-130a-3p BIRC6 2.02 0 -0.21 0.1442 MirTarget; miRNATAP -0.1 0 NA
26 hsa-miR-130a-3p BMPR2 2.02 0 -0.59 4.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
27 hsa-miR-130a-3p BTBD3 2.02 0 -0.6 0.00457 miRNATAP -0.12 0.0002 NA
28 hsa-miR-130a-3p C15orf52 2.02 0 -1.18 0.0026 mirMAP -0.37 0 NA
29 hsa-miR-130a-3p CASD1 2.02 0 -0.65 0.0001 miRNATAP -0.15 0 NA
30 hsa-miR-130a-3p CCDC6 2.02 0 -0.27 0.05122 MirTarget -0.13 0 NA
31 hsa-miR-130a-3p CCDC69 2.02 0 -2.71 0 mirMAP -0.34 0 NA
32 hsa-miR-130a-3p CCDC85A 2.02 0 -1.95 0 miRNATAP -0.26 4.0E-5 NA
33 hsa-miR-130a-3p CCNT1 2.02 0 -0.88 0.01804 mirMAP -0.16 0.00543 NA
34 hsa-miR-130a-3p CDH11 2.02 0 -1.4 0.00163 mirMAP -0.16 0.02209 NA
35 hsa-miR-130a-3p CDH23 2.02 0 -0.59 0.29448 mirMAP -0.41 0 NA
36 hsa-miR-130a-3p CFL2 2.02 0 -2.62 0 MirTarget -0.13 0.00436 NA
37 hsa-miR-130a-3p CHD9 2.02 0 -0.8 1.0E-5 miRNATAP -0.15 0 NA
38 hsa-miR-130a-3p CLCN3 2.02 0 -0.36 0.09942 miRNATAP -0.2 0 NA
39 hsa-miR-130a-3p CLIP1 2.02 0 -0.85 0 MirTarget; miRNATAP -0.17 0 NA
40 hsa-miR-130a-3p CMYA5 2.02 0 -0.74 0.09017 MirTarget -0.27 0.00011 NA
41 hsa-miR-130a-3p CNR2 2.02 0 -2.05 6.0E-5 mirMAP -0.22 0.00611 NA
42 hsa-miR-130a-3p CPEB1 2.02 0 -4.68 0 MirTarget; miRNATAP -0.42 0 NA
43 hsa-miR-130a-3p CPEB3 2.02 0 -1.3 0 MirTarget; miRNATAP -0.22 0 NA
44 hsa-miR-130a-3p CPEB4 2.02 0 -1.56 0 miRNATAP -0.27 0 NA
45 hsa-miR-130a-3p CYP2U1 2.02 0 -1.21 0 MirTarget -0.15 0.00016 NA
46 hsa-miR-130a-3p CYP4F3 2.02 0 -0.23 0.75849 mirMAP -0.43 0.0002 NA
47 hsa-miR-130a-3p DAAM1 2.02 0 -0.94 0.00028 MirTarget; miRNATAP -0.18 1.0E-5 NA
48 hsa-miR-130a-3p DDX6 2.02 0 -0.38 0.00013 MirTarget; miRNATAP -0.1 0 NA
49 hsa-miR-130a-3p DENND4C 2.02 0 -0.64 0.00049 MirTarget -0.13 1.0E-5 NA
50 hsa-miR-130a-3p DGKE 2.02 0 -0.56 0.00391 MirTarget; miRNATAP -0.17 0 NA
51 hsa-miR-130a-3p DLG2 2.02 0 -3.8 0 miRNATAP -0.58 0 NA
52 hsa-miR-130a-3p DMXL1 2.02 0 -0.95 0 miRNATAP -0.14 0 NA
53 hsa-miR-130a-3p DNM3 2.02 0 -1.22 4.0E-5 mirMAP -0.12 0.0136 NA
54 hsa-miR-130a-3p DTNA 2.02 0 -4.06 0 mirMAP -0.27 0.00426 NA
55 hsa-miR-130a-3p EDA 2.02 0 -1.83 3.0E-5 MirTarget; miRNATAP -0.2 0.0036 NA
56 hsa-miR-130a-3p EFR3A 2.02 0 -0.35 0.02542 MirTarget -0.12 0 NA
57 hsa-miR-130a-3p ELL2 2.02 0 -1.08 1.0E-5 MirTarget -0.15 0.00015 NA
58 hsa-miR-130a-3p EMCN 2.02 0 -2.36 0 mirMAP -0.35 0 NA
59 hsa-miR-130a-3p EMX2 2.02 0 -0.58 0.47251 MirTarget; miRNATAP -0.36 0.00501 NA
60 hsa-miR-130a-3p EPM2AIP1 2.02 0 -0.23 0.20238 mirMAP -0.1 0.00033 NA
61 hsa-miR-130a-3p ESR1 2.02 0 -2.87 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.24 0.00117 NA
62 hsa-miR-130a-3p FAM155A 2.02 0 -1.94 0 MirTarget -0.18 0.00544 NA
63 hsa-miR-130a-3p FAM155B 2.02 0 0.33 0.62453 miRNATAP -0.21 0.04367 NA
64 hsa-miR-130a-3p FAT3 2.02 0 -2.79 0 MirTarget -0.33 0.00051 NA
65 hsa-miR-130a-3p FLYWCH1 2.02 0 -0.47 0.00219 mirMAP -0.1 2.0E-5 NA
66 hsa-miR-130a-3p FOXO3 2.02 0 -0.74 0 mirMAP -0.12 0 NA
67 hsa-miR-130a-3p FRMD6 2.02 0 -0.93 0.00183 MirTarget; miRNATAP -0.14 0.00408 NA
68 hsa-miR-130a-3p FRZB 2.02 0 -1.17 0.00146 MirTarget -0.31 0 NA
69 hsa-miR-130a-3p GJA1 2.02 0 -1.07 0.00282 MirTarget; miRNATAP -0.12 0.03063 NA
70 hsa-miR-130a-3p GPR157 2.02 0 -0.17 0.63038 mirMAP -0.24 2.0E-5 NA
71 hsa-miR-130a-3p GRB10 2.02 0 -1.4 0 MirTarget -0.14 0.00155 NA
72 hsa-miR-130a-3p HADHB 2.02 0 -0.37 0.0038 MirTarget -0.1 0 NA
73 hsa-miR-130a-3p HCFC2 2.02 0 -0.81 0 MirTarget -0.1 7.0E-5 NA
74 hsa-miR-130a-3p HERC3 2.02 0 -0.74 0.00166 MirTarget -0.14 0.00014 NA
75 hsa-miR-130a-3p HIPK3 2.02 0 -1.75 0 MirTarget -0.23 0.00011 NA
76 hsa-miR-130a-3p HIVEP2 2.02 0 -0.44 0.01281 miRNATAP -0.11 0.00016 NA
77 hsa-miR-130a-3p ICA1L 2.02 0 -1.18 0 mirMAP -0.15 2.0E-5 NA
78 hsa-miR-130a-3p IDS 2.02 0 -0.67 3.0E-5 mirMAP -0.17 0 NA
79 hsa-miR-130a-3p IGF1 2.02 0 -3.76 0 MirTarget -0.32 0.00086 NA
80 hsa-miR-130a-3p IGF2 2.02 0 0.1 0.91238 mirMAP -0.35 0.01179 NA
81 hsa-miR-130a-3p IKZF4 2.02 0 -0.47 0.00296 miRNATAP -0.15 0 NA
82 hsa-miR-130a-3p IL6R 2.02 0 -1.87 0 mirMAP -0.19 0.00365 NA
83 hsa-miR-130a-3p IL6ST 2.02 0 -2.1 2.0E-5 mirMAP; miRNATAP -0.33 2.0E-5 NA
84 hsa-miR-130a-3p INHBB 2.02 0 -1.64 0 miRNATAP -0.16 0.00317 NA
85 hsa-miR-130a-3p ITGA8 2.02 0 -5.02 0 mirMAP -0.7 0 NA
86 hsa-miR-130a-3p ITIH5 2.02 0 -4.03 0 mirMAP -0.52 0 NA
87 hsa-miR-130a-3p ITPR1 2.02 0 -2.58 0 MirTarget; miRNATAP -0.28 0 NA
88 hsa-miR-130a-3p IYD 2.02 0 1.04 0.14977 mirMAP -0.42 0.00018 NA
89 hsa-miR-130a-3p JAM2 2.02 0 -3.24 0 miRNATAP -0.33 0 NA
90 hsa-miR-130a-3p JMY 2.02 0 -0.98 0 MirTarget; miRNATAP -0.17 0 NA
91 hsa-miR-130a-3p KBTBD8 2.02 0 -1.48 0 MirTarget -0.15 0.0043 NA
92 hsa-miR-130a-3p KCTD20 2.02 0 -0.81 0 MirTarget -0.11 6.0E-5 NA
93 hsa-miR-130a-3p KIAA1462 2.02 0 -1.72 0 MirTarget -0.13 0.01547 NA
94 hsa-miR-130a-3p KIT 2.02 0 -2.52 0 miRNATAP -0.47 0 NA
95 hsa-miR-130a-3p KLF3 2.02 0 -0.63 0.00014 miRNATAP -0.13 0 NA
96 hsa-miR-130a-3p KLF4 2.02 0 -2.67 0 miRNAWalker2 validate; miRTarBase -0.15 0.00519 NA
97 hsa-miR-130a-3p LAMC3 2.02 0 -2.92 0 mirMAP -0.35 0 NA
98 hsa-miR-130a-3p LCOR 2.02 0 -0.36 0.27591 miRNATAP -0.27 0 NA
99 hsa-miR-130a-3p LMTK2 2.02 0 -0.62 0.03087 miRNATAP -0.16 0.00029 NA
100 hsa-miR-130a-3p LNPEP 2.02 0 -0.55 0.02839 MirTarget; miRNATAP -0.12 0.00228 NA
101 hsa-miR-130a-3p LONRF1 2.02 0 -1.15 0 MirTarget; miRNATAP -0.19 0 NA
102 hsa-miR-130a-3p LONRF3 2.02 0 -1.53 0.00011 MirTarget -0.2 0.00136 NA
103 hsa-miR-130a-3p LPP 2.02 0 -2.04 0 mirMAP -0.43 0 NA
104 hsa-miR-130a-3p LTBP4 2.02 0 -2.73 0 mirMAP -0.2 4.0E-5 NA
105 hsa-miR-130a-3p MAF 2.02 0 -1.28 0.00016 miRNATAP -0.13 0.01962 NA
106 hsa-miR-130a-3p MAGI2 2.02 0 -1.89 0 MirTarget -0.24 0 NA
107 hsa-miR-130a-3p MAP3K12 2.02 0 -0.86 0.00031 MirTarget; miRNATAP -0.17 1.0E-5 NA
108 hsa-miR-130a-3p MAPK10 2.02 0 -1.4 0.00097 miRNATAP -0.43 0 NA
109 hsa-miR-130a-3p MAPRE3 2.02 0 -0.37 0.12897 MirTarget; miRNATAP -0.13 0.00081 NA
110 hsa-miR-130a-3p MARCH2 2.02 0 -0.63 2.0E-5 MirTarget; miRNATAP -0.11 0 NA
111 hsa-miR-130a-3p MBNL1 2.02 0 -1.04 0 MirTarget; miRNATAP -0.14 0 NA
112 hsa-miR-130a-3p MBNL3 2.02 0 -1.4 8.0E-5 MirTarget; mirMAP; miRNATAP -0.31 0 NA
113 hsa-miR-130a-3p MCC 2.02 0 -1.14 0.00045 MirTarget -0.18 0.00065 NA
114 hsa-miR-130a-3p MEOX2 2.02 0 -3.62 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.34 0.00068 NA
115 hsa-miR-130a-3p MFSD6 2.02 0 -0.42 0.02585 miRNATAP -0.18 0 NA
116 hsa-miR-130a-3p MID1IP1 2.02 0 -0.31 0.13185 miRNATAP -0.13 0.00011 NA
117 hsa-miR-130a-3p MIPOL1 2.02 0 -0.47 0.07981 mirMAP -0.14 0.00128 NA
118 hsa-miR-130a-3p MPPED2 2.02 0 -2.5 4.0E-5 MirTarget -0.47 0 NA
119 hsa-miR-130a-3p MTMR10 2.02 0 -0.94 0 MirTarget -0.14 0 NA
120 hsa-miR-130a-3p MUC20 2.02 0 0.96 0.11285 mirMAP -0.28 0.00313 NA
121 hsa-miR-130a-3p MYT1 2.02 0 1.33 0.10984 MirTarget; miRNATAP -0.32 0.01721 NA
122 hsa-miR-130a-3p NACC2 2.02 0 -1.56 0 miRNATAP -0.1 0.00839 NA
123 hsa-miR-130a-3p NAP1L3 2.02 0 -2.72 0 MirTarget -0.21 0.00329 NA
124 hsa-miR-130a-3p NBEA 2.02 0 -3.53 0 MirTarget; miRNATAP -0.36 1.0E-5 NA
125 hsa-miR-130a-3p NCKAP5 2.02 0 -0.57 0.21529 MirTarget -0.25 0.00046 NA
126 hsa-miR-130a-3p NCOA1 2.02 0 -0.56 0.0002 MirTarget; miRNATAP -0.12 0 NA
127 hsa-miR-130a-3p NFIA 2.02 0 -2.1 0 miRNATAP -0.18 4.0E-5 NA
128 hsa-miR-130a-3p NFIC 2.02 0 -1.57 0 miRNATAP -0.17 9.0E-5 NA
129 hsa-miR-130a-3p NHS 2.02 0 -0.63 0.03816 miRNATAP -0.2 2.0E-5 NA
130 hsa-miR-130a-3p NKAIN2 2.02 0 -1.18 0.10862 MirTarget -0.38 0.00127 NA
131 hsa-miR-130a-3p NOL4 2.02 0 -3.94 0 miRNATAP -0.42 1.0E-5 NA
132 hsa-miR-130a-3p NPTN 2.02 0 -0.74 0 MirTarget; miRNATAP -0.15 0 NA
133 hsa-miR-130a-3p NPTX1 2.02 0 -3.05 0 miRNATAP -0.28 0.00082 NA
134 hsa-miR-130a-3p NPTXR 2.02 0 -1.27 0.01306 mirMAP -0.34 2.0E-5 NA
135 hsa-miR-130a-3p NT5C2 2.02 0 0.27 0.15823 mirMAP -0.13 1.0E-5 NA
136 hsa-miR-130a-3p NUDT4 2.02 0 -0.29 0.20205 mirMAP -0.22 0 NA
137 hsa-miR-130a-3p PARD3B 2.02 0 -3 0 mirMAP -0.38 0 NA
138 hsa-miR-130a-3p PARD6G 2.02 0 0.1 0.69472 mirMAP -0.11 0.00839 NA
139 hsa-miR-130a-3p PDE4C 2.02 0 -0.56 0.2024 mirMAP -0.23 0.00112 NA
140 hsa-miR-130a-3p PDGFRA 2.02 0 -2.38 0 MirTarget; miRNATAP -0.23 0.00022 NA
141 hsa-miR-130a-3p PGAP1 2.02 0 -0.42 0.10053 MirTarget -0.19 0 NA
142 hsa-miR-130a-3p PGR 2.02 0 -3.89 0 mirMAP -0.3 2.0E-5 NA
143 hsa-miR-130a-3p PIK3IP1 2.02 0 0.04 0.87074 miRNATAP -0.19 0 NA
144 hsa-miR-130a-3p PIKFYVE 2.02 0 -0.44 0.00371 MirTarget -0.11 0 NA
145 hsa-miR-130a-3p PLCB1 2.02 0 -1.23 2.0E-5 miRNATAP -0.28 0 NA
146 hsa-miR-130a-3p PLEKHA2 2.02 0 -0.68 0.00026 mirMAP -0.15 0 NA
147 hsa-miR-130a-3p PLEKHA5 2.02 0 -0.52 0.00633 mirMAP -0.1 0.00054 NA
148 hsa-miR-130a-3p PPARG 2.02 0 0.8 0.14249 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.21 0.01438 NA
149 hsa-miR-130a-3p PPARGC1A 2.02 0 -4.12 0 miRNATAP -0.42 5.0E-5 NA
150 hsa-miR-130a-3p PPP1R12B 2.02 0 -3.46 0 mirMAP -0.43 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 33 1036 1.211e-06 0.0007199
2 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 48 1805 7.466e-07 0.0007199
3 POSITIVE REGULATION OF GENE EXPRESSION 47 1733 5.72e-07 0.0007199
4 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 33 1036 1.211e-06 0.0007199
5 REGULATION OF CELL DIFFERENTIATION 42 1492 9.78e-07 0.0007199
6 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 33 1008 6.618e-07 0.0007199
7 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 8 60 9.032e-07 0.0007199
8 POSITIVE REGULATION OF OSSIFICATION 9 84 1.238e-06 0.0007199
9 REGULATION OF OSTEOBLAST DIFFERENTIATION 10 112 1.723e-06 0.0008907
10 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 25 689 2.814e-06 0.001305
11 NEUROGENESIS 39 1402 3.365e-06 0.001305
12 REGULATION OF OSSIFICATION 12 178 3.175e-06 0.001305
13 REPRODUCTIVE SYSTEM DEVELOPMENT 18 408 5.473e-06 0.001959
14 RESPONSE TO ENDOGENOUS STIMULUS 39 1450 7.44e-06 0.002308
15 POSITIVE REGULATION OF CELL DIFFERENTIATION 27 823 7.165e-06 0.002308
16 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 33 1142 9.594e-06 0.00279
17 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 44 1784 1.602e-05 0.004385
18 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 24 724 2.007e-05 0.004921
19 CENTRAL NERVOUS SYSTEM DEVELOPMENT 27 872 2.009e-05 0.004921
20 CELLULAR RESPONSE TO HORMONE STIMULUS 20 552 2.949e-05 0.006793
21 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 38 1492 3.318e-05 0.006793
22 RHYTHMIC PROCESS 14 298 3.102e-05 0.006793
23 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 29 1004 3.504e-05 0.006793
24 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 11 190 3.407e-05 0.006793
25 POSITIVE REGULATION OF MOLECULAR FUNCTION 43 1791 3.853e-05 0.007106
26 SEX DIFFERENTIATION 13 266 3.971e-05 0.007106
27 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 8 100 4.237e-05 0.007302
28 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 31 1135 5.328e-05 0.008854
NumGOOverlapSizeP ValueAdj. P Value
1 PHOSPHATIDYLINOSITOL BINDING 13 200 1.852e-06 0.0008602
2 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 5 17 1.769e-06 0.0008602
3 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 8 81 9.017e-06 0.002369
4 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 34 1199 1.032e-05 0.002369
5 LIPID BINDING 23 657 1.275e-05 0.002369
6 PHOSPHOLIPID BINDING 16 360 1.675e-05 0.002594
7 INSULIN RECEPTOR BINDING 5 32 4.923e-05 0.006534
8 RECEPTOR SIGNALING PROTEIN ACTIVITY 10 172 7.475e-05 0.00868
9 X1 PHOSPHATIDYLINOSITOL BINDING 4 19 8.604e-05 0.008882
NumGOOverlapSizeP ValueAdj. P Value
1 EXCITATORY SYNAPSE 12 197 8.993e-06 0.005252

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 10 139 1.201e-05 0.0006244
2 Endocytosis_hsa04144 12 244 7.401e-05 0.001717
3 TGF_beta_signaling_pathway_hsa04350 7 84 9.908e-05 0.001717
4 Gap_junction_hsa04540 7 88 0.000133 0.001729
5 Oocyte_meiosis_hsa04114 8 124 0.0001929 0.002006
6 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.000477 0.004134
7 Hippo_signaling_pathway_hsa04390 8 154 0.0008246 0.006125
8 Rap1_signaling_pathway_hsa04015 9 206 0.001353 0.008797
9 Cytokine_cytokine_receptor_interaction_hsa04060 10 270 0.002538 0.01418
10 Phospholipase_D_signaling_pathway_hsa04072 7 146 0.002726 0.01418
11 Focal_adhesion_hsa04510 8 199 0.00411 0.01943
12 Regulation_of_actin_cytoskeleton_hsa04810 8 208 0.005347 0.02317
13 FoxO_signaling_pathway_hsa04068 6 132 0.006981 0.02793
14 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.008772 0.03258
15 p53_signaling_pathway_hsa04115 4 68 0.01111 0.03852
16 Adherens_junction_hsa04520 4 72 0.0135 0.04206
17 MAPK_signaling_pathway_hsa04010 9 295 0.01375 0.04206
18 Tight_junction_hsa04530 6 170 0.02203 0.06365
19 Apelin_signaling_pathway_hsa04371 5 137 0.03119 0.08537
20 PI3K_Akt_signaling_pathway_hsa04151 9 352 0.03727 0.0969
21 mTOR_signaling_pathway_hsa04150 5 151 0.0444 0.1099
22 Mitophagy_animal_hsa04137 3 65 0.05023 0.1187
23 Cellular_senescence_hsa04218 5 160 0.05442 0.123
24 cGMP_PKG_signaling_pathway_hsa04022 5 163 0.05803 0.1257
25 Sphingolipid_signaling_pathway_hsa04071 4 118 0.06444 0.1321
26 Apoptosis_multiple_species_hsa04215 2 33 0.06603 0.1321
27 AMPK_signaling_pathway_hsa04152 4 121 0.06932 0.1335
28 Ras_signaling_pathway_hsa04014 6 232 0.07729 0.1435
29 Calcium_signaling_pathway_hsa04020 5 182 0.08397 0.1506
30 Wnt_signaling_pathway_hsa04310 4 146 0.1169 0.2026
31 Autophagy_animal_hsa04140 3 128 0.224 0.3757
32 cAMP_signaling_pathway_hsa04024 4 198 0.2465 0.4005
33 ECM_receptor_interaction_hsa04512 2 82 0.2811 0.4314
34 Cell_adhesion_molecules_.CAMs._hsa04514 3 145 0.282 0.4314
35 ErbB_signaling_pathway_hsa04012 2 85 0.2953 0.4387
36 Jak_STAT_signaling_pathway_hsa04630 3 162 0.3412 0.4929
37 HIF_1_signaling_pathway_hsa04066 2 100 0.3652 0.5132
38 TNF_signaling_pathway_hsa04668 2 108 0.4014 0.5357
39 Apoptosis_hsa04210 2 138 0.5273 0.658
40 Phagosome_hsa04145 2 152 0.5796 0.7009
41 Neuroactive_ligand_receptor_interaction_hsa04080 2 278 0.8722 0.9727

Quest ID: 30ad206d6cd4525f9d0b9856c21309ac