Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-3p ABCA1 0.89 0 0.11 0.40751 mirMAP; miRNATAP -0.18 0.00021 NA
2 hsa-let-7a-3p ABCC9 0.89 0 -1.23 0 mirMAP -0.87 0 NA
3 hsa-let-7a-3p ABCD2 0.89 0 -1.33 0 mirMAP -0.82 0 NA
4 hsa-let-7a-3p ABCD3 0.89 0 -0.51 0 MirTarget -0.14 0 NA
5 hsa-let-7a-3p ABI3BP 0.89 0 -0.79 1.0E-5 miRNATAP -0.71 0 NA
6 hsa-let-7a-3p ABLIM1 0.89 0 -0.73 0 mirMAP -0.3 0 NA
7 hsa-let-7a-3p ACAP2 0.89 0 -0.26 0.00083 MirTarget; mirMAP; miRNATAP -0.17 0 NA
8 hsa-let-7a-3p ACOT11 0.89 0 -1.43 0 mirMAP -0.41 0 NA
9 hsa-let-7a-3p ACTR3 0.89 0 -0.13 0.01918 MirTarget; miRNATAP -0.1 0 NA
10 hsa-let-7a-3p ACVR1 0.89 0 -0.14 0.03614 MirTarget; miRNATAP -0.17 0 NA
11 hsa-let-7a-3p ADAM23 0.89 0 -1.03 0 mirMAP -0.73 0 NA
12 hsa-let-7a-3p ADAMTS5 0.89 0 -1.91 0 mirMAP -0.88 0 NA
13 hsa-let-7a-3p ADAMTSL3 0.89 0 -1.17 0 MirTarget -0.76 0 NA
14 hsa-let-7a-3p ADCYAP1 0.89 0 -0.26 0.34833 miRNATAP -0.51 0 NA
15 hsa-let-7a-3p ADD3 0.89 0 -0.99 0 mirMAP; miRNATAP -0.33 0 NA
16 hsa-let-7a-3p ADH5 0.89 0 -0.46 0 MirTarget -0.18 0 NA
17 hsa-let-7a-3p AFF2 0.89 0 -1.9 0 mirMAP -0.82 0 NA
18 hsa-let-7a-3p AFF3 0.89 0 -0.06 0.78798 MirTarget -0.28 0.00181 NA
19 hsa-let-7a-3p AFF4 0.89 0 -0.21 0.01507 MirTarget; mirMAP -0.19 0 NA
20 hsa-let-7a-3p AHDC1 0.89 0 -0.63 0 miRNATAP -0.24 0 NA
21 hsa-let-7a-3p AHR 0.89 0 -1.07 0 MirTarget -0.54 0 NA
22 hsa-let-7a-3p AKAP11 0.89 0 -0.67 0 mirMAP -0.32 0 NA
23 hsa-let-7a-3p AKAP12 0.89 0 -0.92 0 miRNATAP -0.43 0 NA
24 hsa-let-7a-3p ALDH1L2 0.89 0 -1.86 0 MirTarget -0.93 0 NA
25 hsa-let-7a-3p ALKBH8 0.89 0 -0.3 0 MirTarget -0.13 0 NA
26 hsa-let-7a-3p AMIGO2 0.89 0 -0.96 0 MirTarget; mirMAP -0.38 0 NA
27 hsa-let-7a-3p AMOT 0.89 0 -1.24 0 mirMAP -0.46 0 NA
28 hsa-let-7a-3p AMOTL1 0.89 0 -0.38 0.00203 mirMAP -0.12 0.01684 NA
29 hsa-let-7a-3p AMOTL2 0.89 0 -0.73 0 miRNATAP -0.42 0 NA
30 hsa-let-7a-3p ANKRD17 0.89 0 -0.05 0.56613 MirTarget -0.13 0.00042 NA
31 hsa-let-7a-3p ANKRD50 0.89 0 0.05 0.63242 mirMAP -0.22 0 NA
32 hsa-let-7a-3p ANKS1B 0.89 0 -0.24 0.05633 miRNATAP -0.2 7.0E-5 NA
33 hsa-let-7a-3p ANO1 0.89 0 -1.77 0 MirTarget; miRNATAP -0.61 0 NA
34 hsa-let-7a-3p ANO4 0.89 0 -1.68 0 MirTarget; miRNATAP -0.88 0 NA
35 hsa-let-7a-3p ANO5 0.89 0 -1.93 0 mirMAP -1.04 0 NA
36 hsa-let-7a-3p ANTXR1 0.89 0 -0.95 0 mirMAP; miRNATAP -0.59 0 NA
37 hsa-let-7a-3p AP3B1 0.89 0 -0.22 0.00076 mirMAP -0.15 0 NA
38 hsa-let-7a-3p APC 0.89 0 -0.32 0.0021 mirMAP -0.23 0 NA
39 hsa-let-7a-3p APLF 0.89 0 -0.91 0 MirTarget -0.39 0 NA
40 hsa-let-7a-3p APP 0.89 0 -0.48 2.0E-5 MirTarget; miRNATAP -0.24 0 NA
41 hsa-let-7a-3p APPBP2 0.89 0 -0.1 0.10538 mirMAP; miRNATAP -0.1 3.0E-5 NA
42 hsa-let-7a-3p AQP9 0.89 0 -1.39 0 MirTarget -0.43 0 NA
43 hsa-let-7a-3p ARAP2 0.89 0 -0.04 0.69531 MirTarget; miRNATAP -0.14 0.00097 NA
44 hsa-let-7a-3p ARFGEF2 0.89 0 -0.32 0.00076 miRNATAP -0.21 0 NA
45 hsa-let-7a-3p ARHGAP12 0.89 0 0.05 0.57049 miRNATAP -0.14 2.0E-5 NA
46 hsa-let-7a-3p ARHGAP20 0.89 0 -1.96 0 MirTarget; miRNATAP -0.94 0 NA
47 hsa-let-7a-3p ARHGAP29 0.89 0 0.08 0.42071 mirMAP -0.13 0.00094 NA
48 hsa-let-7a-3p ARHGAP5 0.89 0 -0.4 0 mirMAP -0.23 0 NA
49 hsa-let-7a-3p ARHGEF3 0.89 0 -0.29 0.00214 MirTarget -0.13 0.00063 NA
50 hsa-let-7a-3p ARHGEF33 0.89 0 -0.47 4.0E-5 miRNATAP -0.17 0.00016 NA
51 hsa-let-7a-3p ARID4A 0.89 0 -0.39 0 MirTarget; miRNATAP -0.21 0 NA
52 hsa-let-7a-3p ARID5B 0.89 0 0.15 0.08049 miRNATAP -0.13 0.00015 NA
53 hsa-let-7a-3p ARIH1 0.89 0 -0.12 0.01391 MirTarget -0.11 0 NA
54 hsa-let-7a-3p ARL10 0.89 0 -1.23 0 mirMAP -0.59 0 NA
55 hsa-let-7a-3p ARL5A 0.89 0 0.02 0.81829 MirTarget; mirMAP -0.1 0.00061 NA
56 hsa-let-7a-3p ARMC8 0.89 0 -0.23 1.0E-5 miRNAWalker2 validate -0.14 0 NA
57 hsa-let-7a-3p ARNTL 0.89 0 -0.59 0 MirTarget; miRNATAP -0.19 0 NA
58 hsa-let-7a-3p ARPP19 0.89 0 -0.35 0 MirTarget -0.14 0 NA
59 hsa-let-7a-3p ARRDC3 0.89 0 -0.49 2.0E-5 MirTarget -0.29 0 NA
60 hsa-let-7a-3p ARSB 0.89 0 -0.32 0.00016 mirMAP -0.28 0 NA
61 hsa-let-7a-3p ASAP1 0.89 0 -0.59 0 mirMAP -0.36 0 NA
62 hsa-let-7a-3p ASPH 0.89 0 -1.11 0 mirMAP -0.3 0 NA
63 hsa-let-7a-3p ASXL2 0.89 0 -0.8 0.00011 mirMAP; miRNATAP -0.55 0 NA
64 hsa-let-7a-3p ATE1 0.89 0 -0.66 2.0E-5 mirMAP -0.4 0 NA
65 hsa-let-7a-3p ATF1 0.89 0 -0.19 0.00704 MirTarget -0.15 0 NA
66 hsa-let-7a-3p ATF2 0.89 0 -0.55 4.0E-5 MirTarget; mirMAP; miRNATAP -0.36 0 NA
67 hsa-let-7a-3p ATL2 0.89 0 -0.4 0 MirTarget -0.24 0 NA
68 hsa-let-7a-3p ATRX 0.89 0 -0.29 0.00078 MirTarget; miRNATAP -0.21 0 NA
69 hsa-let-7a-3p AUTS2 0.89 0 -0.38 0.00118 miRNATAP -0.19 3.0E-5 NA
70 hsa-let-7a-3p AXIN2 0.89 0 -0.4 0.00023 miRNATAP -0.25 0 NA
71 hsa-let-7a-3p B2M 0.89 0 -0.2 0.04836 mirMAP -0.2 0 NA
72 hsa-let-7a-3p B3GALNT1 0.89 0 -0.56 5.0E-5 mirMAP -0.31 0 NA
73 hsa-let-7a-3p B3GNT2 0.89 0 -0.33 0.00016 MirTarget; miRNATAP -0.24 0 NA
74 hsa-let-7a-3p BACH1 0.89 0 0.18 0.04671 MirTarget; mirMAP -0.14 7.0E-5 NA
75 hsa-let-7a-3p BAG4 0.89 0 -0.8 0 mirMAP -0.4 0 NA
76 hsa-let-7a-3p BCAS1 0.89 0 0.63 0.00395 mirMAP -0.19 0.02618 NA
77 hsa-let-7a-3p BCL11A 0.89 0 -1.44 0 mirMAP -0.35 0.00011 NA
78 hsa-let-7a-3p BCL11B 0.89 0 -0.6 0.00098 mirMAP; miRNATAP -0.35 0 NA
79 hsa-let-7a-3p BCL6 0.89 0 -0.36 0.00062 miRNATAP -0.27 0 NA
80 hsa-let-7a-3p BDNF 0.89 0 -1.66 0 MirTarget; miRNATAP -0.75 0 NA
81 hsa-let-7a-3p BDP1 0.89 0 -0.16 0.12278 MirTarget; mirMAP -0.15 0.00022 NA
82 hsa-let-7a-3p BEND6 0.89 0 -0.83 0 mirMAP -0.49 0 NA
83 hsa-let-7a-3p BHLHE40 0.89 0 -0.65 0.0001 MirTarget; miRNATAP -0.33 0 NA
84 hsa-let-7a-3p BICD2 0.89 0 -0.51 0 mirMAP -0.16 0 NA
85 hsa-let-7a-3p BMP2K 0.89 0 -0.18 0.09946 mirMAP -0.24 0 NA
86 hsa-let-7a-3p BMP3 0.89 0 -0.66 0.018 MirTarget; mirMAP -0.61 0 NA
87 hsa-let-7a-3p BMPER 0.89 0 -1.42 0 MirTarget -0.94 0 NA
88 hsa-let-7a-3p BMPR2 0.89 0 -0.33 8.0E-5 MirTarget; miRNATAP -0.25 0 NA
89 hsa-let-7a-3p BNC1 0.89 0 -1.69 0 MirTarget -0.69 0 NA
90 hsa-let-7a-3p BNC2 0.89 0 -1.29 0 mirMAP -0.78 0 NA
91 hsa-let-7a-3p BNIP2 0.89 0 -0.57 0 mirMAP -0.19 0 NA
92 hsa-let-7a-3p BST1 0.89 0 -0.6 5.0E-5 MirTarget -0.43 0 NA
93 hsa-let-7a-3p BTBD7 0.89 0 -0.31 0 mirMAP; miRNATAP -0.14 0 NA
94 hsa-let-7a-3p BTC 0.89 0 -0.44 0.00473 mirMAP -0.41 0 NA
95 hsa-let-7a-3p BVES 0.89 0 -1.18 0 mirMAP -0.46 0 NA
96 hsa-let-7a-3p C4orf32 0.89 0 -0.13 0.20703 mirMAP -0.14 0.00026 NA
97 hsa-let-7a-3p C4orf33 0.89 0 -0.36 0.00063 miRNATAP -0.14 0.00125 NA
98 hsa-let-7a-3p C8orf46 0.89 0 -0.83 0 mirMAP -0.26 3.0E-5 NA
99 hsa-let-7a-3p CACNA1C 0.89 0 -0.77 0 MirTarget -0.58 0 NA
100 hsa-let-7a-3p CACNA2D1 0.89 0 -1.61 0 mirMAP -1.15 0 NA
101 hsa-let-7a-3p CACNB2 0.89 0 -0.41 0.0001 MirTarget; mirMAP -0.25 0 NA
102 hsa-let-7a-3p CACNG4 0.89 0 -0.66 0.01429 MirTarget -0.35 0.00089 NA
103 hsa-let-7a-3p CALN1 0.89 0 -1.52 0 mirMAP -0.35 0.00563 NA
104 hsa-let-7a-3p CAPZA2 0.89 0 -0.39 0 MirTarget -0.18 0 NA
105 hsa-let-7a-3p CASP8AP2 0.89 0 -0.61 1.0E-5 MirTarget -0.3 0 NA
106 hsa-let-7a-3p CBL 0.89 0 -0.31 0.00068 MirTarget -0.25 0 NA
107 hsa-let-7a-3p CCDC102B 0.89 0 -0.2 0.08979 MirTarget -0.11 0.01421 NA
108 hsa-let-7a-3p CCND2 0.89 0 -1.36 0 mirMAP -0.61 0 20418948 MicroRNA let 7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
109 hsa-let-7a-3p CCPG1 0.89 0 -0.16 0.06596 mirMAP -0.17 0 NA
110 hsa-let-7a-3p CD109 0.89 0 -0.6 5.0E-5 mirMAP -0.32 0 NA
111 hsa-let-7a-3p CD302 0.89 0 0.1 0.25044 mirMAP -0.19 0 NA
112 hsa-let-7a-3p CD38 0.89 0 -2.17 0 MirTarget -0.56 0.00037 NA
113 hsa-let-7a-3p CD44 0.89 0 -0.45 0.00096 miRNATAP -0.3 0 NA
114 hsa-let-7a-3p CD46 0.89 0 -0.24 0.0032 mirMAP -0.13 4.0E-5 NA
115 hsa-let-7a-3p CDC14A 0.89 0 0.28 0.03646 mirMAP -0.2 0.00019 NA
116 hsa-let-7a-3p CDC14B 0.89 0 -0.7 0 miRNATAP -0.23 0 NA
117 hsa-let-7a-3p CDC42EP3 0.89 0 -1.17 0 MirTarget; mirMAP -0.6 0 NA
118 hsa-let-7a-3p CDC73 0.89 0 -0.18 0.01178 mirMAP; miRNATAP -0.14 0 NA
119 hsa-let-7a-3p CDK6 0.89 0 -0.06 0.70453 miRNATAP -0.22 0.00106 NA
120 hsa-let-7a-3p CDS2 0.89 0 -0.33 0 mirMAP -0.14 0 NA
121 hsa-let-7a-3p CELF2 0.89 0 -1.12 0 miRNATAP -0.68 0 NA
122 hsa-let-7a-3p CEP76 0.89 0 -0.15 0.05291 MirTarget -0.13 1.0E-5 NA
123 hsa-let-7a-3p CFL2 0.89 0 -1.33 0 mirMAP -0.54 0 NA
124 hsa-let-7a-3p CFTR 0.89 0 -1 0.00504 MirTarget -0.83 0 NA
125 hsa-let-7a-3p CHD1 0.89 0 -0.2 0.07933 MirTarget -0.19 2.0E-5 NA
126 hsa-let-7a-3p CHD9 0.89 0 -0.75 0 mirMAP; miRNATAP -0.29 0 NA
127 hsa-let-7a-3p CHL1 0.89 0 -0.41 0.12478 MirTarget; miRNATAP -0.59 0 NA
128 hsa-let-7a-3p CHM 0.89 0 -0.37 0.00025 MirTarget -0.29 0 NA
129 hsa-let-7a-3p CHMP1B 0.89 0 -0.45 0 mirMAP -0.14 0 NA
130 hsa-let-7a-3p CHRNA7 0.89 0 -1.9 0 mirMAP -0.7 0 NA
131 hsa-let-7a-3p CHST2 0.89 0 -1.52 0 MirTarget -0.47 0 NA
132 hsa-let-7a-3p CLDN1 0.89 0 -0.92 2.0E-5 MirTarget -0.39 1.0E-5 NA
133 hsa-let-7a-3p CLIC4 0.89 0 -0.99 0 MirTarget -0.56 0 NA
134 hsa-let-7a-3p CLIP1 0.89 0 -0.26 0.00173 miRNATAP -0.18 0 NA
135 hsa-let-7a-3p CLOCK 0.89 0 -0.61 0.00038 MirTarget -0.45 0 NA
136 hsa-let-7a-3p CNKSR2 0.89 0 0.21 0.43727 MirTarget; mirMAP; miRNATAP -0.42 4.0E-5 NA
137 hsa-let-7a-3p CNOT7 0.89 0 -0.37 0 MirTarget -0.11 0 NA
138 hsa-let-7a-3p CNR1 0.89 0 -1.28 0 mirMAP -0.68 0 NA
139 hsa-let-7a-3p CNTN1 0.89 0 -1.78 0 MirTarget; miRNATAP -1.3 0 NA
140 hsa-let-7a-3p COBLL1 0.89 0 0.22 0.03803 mirMAP -0.13 0.00164 NA
141 hsa-let-7a-3p COL12A1 0.89 0 0.47 0.03393 miRNATAP -0.22 0.01206 NA
142 hsa-let-7a-3p COL13A1 0.89 0 -1.11 0 miRNATAP -0.64 0 NA
143 hsa-let-7a-3p COL15A1 0.89 0 0.26 0.06683 MirTarget -0.4 0 NA
144 hsa-let-7a-3p COL1A2 0.89 0 -0.07 0.65936 MirTarget -0.37 0 NA
145 hsa-let-7a-3p COL4A1 0.89 0 -0.47 0.00116 miRNATAP -0.5 0 NA
146 hsa-let-7a-3p COL4A3BP 0.89 0 -0.23 0.00637 MirTarget; mirMAP; miRNATAP -0.15 1.0E-5 NA
147 hsa-let-7a-3p COL4A4 0.89 0 -0.88 0 mirMAP -0.7 0 NA
148 hsa-let-7a-3p COL9A1 0.89 0 -1.52 2.0E-5 mirMAP -0.93 0 NA
149 hsa-let-7a-3p CORO1C 0.89 0 -0.91 0 MirTarget; miRNATAP -0.43 0 NA
150 hsa-let-7a-3p CPD 0.89 0 0.15 0.11255 mirMAP; miRNATAP -0.12 0.00085 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 151 1672 4.55e-22 2.117e-18
2 NEUROGENESIS 134 1402 1.049e-21 2.442e-18
3 REGULATION OF CELL DIFFERENTIATION 136 1492 3.535e-20 5.482e-17
4 REGULATION OF CELL DEVELOPMENT 93 836 2.088e-19 2.429e-16
5 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 86 750 8.038e-19 7.48e-16
6 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 138 1656 4.352e-17 3.029e-14
7 POSITIVE REGULATION OF GENE EXPRESSION 142 1733 5.859e-17 3.029e-14
8 CARDIOVASCULAR SYSTEM DEVELOPMENT 85 788 5.636e-17 3.029e-14
9 CIRCULATORY SYSTEM DEVELOPMENT 85 788 5.636e-17 3.029e-14
10 POSITIVE REGULATION OF MOLECULAR FUNCTION 145 1791 7.201e-17 3.351e-14
11 REGULATION OF HYDROLASE ACTIVITY 118 1327 1.091e-16 4.617e-14
12 TISSUE DEVELOPMENT 128 1518 3.009e-16 1.167e-13
13 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 105 1142 7.222e-16 2.585e-13
14 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 141 1784 1.565e-15 5.202e-13
15 REGULATION OF GTPASE ACTIVITY 74 673 2.49e-15 7.723e-13
16 REGULATION OF CELLULAR COMPONENT MOVEMENT 80 771 4.461e-15 1.297e-12
17 POSITIVE REGULATION OF CATALYTIC ACTIVITY 124 1518 1.024e-14 2.803e-12
18 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 110 1275 1.117e-14 2.888e-12
19 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 94 1008 1.209e-14 2.96e-12
20 CELL DEVELOPMENT 118 1426 2.05e-14 4.77e-12
21 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 93 1021 6.953e-14 1.541e-11
22 REGULATION OF PROTEIN MODIFICATION PROCESS 132 1710 9.05e-14 1.914e-11
23 LOCOMOTION 98 1114 1.174e-13 2.376e-11
24 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 71 689 2.424e-13 4.699e-11
25 RESPONSE TO ENDOGENOUS STIMULUS 116 1450 3.56e-13 6.625e-11
26 CELL PROJECTION ORGANIZATION 84 902 3.859e-13 6.906e-11
27 NEGATIVE REGULATION OF CELL COMMUNICATION 101 1192 4.833e-13 8.328e-11
28 NEURON DIFFERENTIATION 82 874 5.082e-13 8.445e-11
29 POSITIVE REGULATION OF CELL COMMUNICATION 120 1532 5.567e-13 8.931e-11
30 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 134 1805 1.028e-12 1.594e-10
31 ORGAN MORPHOGENESIS 79 841 1.32e-12 1.982e-10
32 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 111 1395 1.762e-12 2.562e-10
33 EPITHELIUM DEVELOPMENT 85 945 1.819e-12 2.564e-10
34 HEART DEVELOPMENT 54 466 2.228e-12 3.048e-10
35 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 88 1004 2.944e-12 3.914e-10
36 REGULATION OF PHOSPHORUS METABOLIC PROCESS 122 1618 4.634e-12 5.99e-10
37 REGULATION OF CELLULAR COMPONENT BIOGENESIS 73 767 5.377e-12 6.762e-10
38 POSITIVE REGULATION OF RESPONSE TO STIMULUS 138 1929 6.693e-12 8.195e-10
39 REGULATION OF NEURON DIFFERENTIATION 59 554 7.329e-12 8.744e-10
40 HEAD DEVELOPMENT 69 709 7.755e-12 9.02e-10
41 VASCULATURE DEVELOPMENT 53 469 9.463e-12 1.048e-09
42 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 55 498 9.403e-12 1.048e-09
43 NEURON PROJECTION DEVELOPMENT 58 545 1.145e-11 1.239e-09
44 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 95 1152 1.208e-11 1.277e-09
45 INTRACELLULAR SIGNAL TRANSDUCTION 118 1572 1.48e-11 1.53e-09
46 CELLULAR COMPONENT MORPHOGENESIS 80 900 1.567e-11 1.569e-09
47 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 74 801 1.585e-11 1.569e-09
48 TUBE DEVELOPMENT 58 552 1.918e-11 1.859e-09
49 POSITIVE REGULATION OF CELL DIFFERENTIATION 75 823 2.199e-11 2.088e-09
50 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 55 513 2.992e-11 2.784e-09
51 MORPHOGENESIS OF AN EPITHELIUM 47 400 3.819e-11 3.485e-09
52 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 82 957 5.436e-11 4.864e-09
53 REGULATION OF CELL PROLIFERATION 112 1496 6.246e-11 5.484e-09
54 BLOOD VESSEL MORPHOGENESIS 44 364 6.425e-11 5.536e-09
55 EMBRYO DEVELOPMENT 78 894 7.056e-11 5.969e-09
56 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 49 437 7.737e-11 6.429e-09
57 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 104 1360 1.002e-10 8.177e-09
58 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 111 1492 1.124e-10 9.019e-09
59 REGULATION OF MAPK CASCADE 63 660 1.477e-10 1.165e-08
60 PROTEIN PHOSPHORYLATION 80 944 1.62e-10 1.256e-08
61 EMBRYONIC MORPHOGENESIS 55 539 1.966e-10 1.5e-08
62 REGULATION OF CELL PROJECTION ORGANIZATION 56 558 2.514e-10 1.887e-08
63 POSITIVE REGULATION OF HYDROLASE ACTIVITY 77 905 3.057e-10 2.258e-08
64 CENTRAL NERVOUS SYSTEM DEVELOPMENT 75 872 3.241e-10 2.356e-08
65 POSITIVE REGULATION OF CELL DEVELOPMENT 50 472 3.7e-10 2.649e-08
66 TISSUE MORPHOGENESIS 54 533 3.758e-10 2.649e-08
67 RESPONSE TO GROWTH FACTOR 50 475 4.613e-10 3.203e-08
68 NEURON DEVELOPMENT 63 687 7.517e-10 5.144e-08
69 NEGATIVE REGULATION OF CELL DIFFERENTIATION 58 609 8.911e-10 6.009e-08
70 REGULATION OF CELL DEATH 107 1472 9.568e-10 6.36e-08
71 REGULATION OF KINASE ACTIVITY 68 776 1.058e-09 6.933e-08
72 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 80 983 1.093e-09 7.065e-08
73 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 88 1135 1.668e-09 1.063e-07
74 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 82 1036 2.45e-09 1.514e-07
75 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 82 1036 2.45e-09 1.514e-07
76 REGULATION OF NEURON PROJECTION DEVELOPMENT 44 408 2.474e-09 1.514e-07
77 NEGATIVE REGULATION OF CELL PROLIFERATION 59 643 2.605e-09 1.574e-07
78 MORPHOGENESIS OF A BRANCHING STRUCTURE 26 167 2.811e-09 1.658e-07
79 TUBE MORPHOGENESIS 38 323 2.816e-09 1.658e-07
80 REGULATION OF CELL ADHESION 58 629 2.98e-09 1.733e-07
81 REGULATION OF EPITHELIAL CELL PROLIFERATION 35 285 3.878e-09 2.228e-07
82 REGULATION OF TRANSFERASE ACTIVITY 76 946 5.185e-09 2.942e-07
83 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 63 724 5.877e-09 3.294e-07
84 RESPONSE TO ORGANIC CYCLIC COMPOUND 74 917 6.927e-09 3.837e-07
85 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 67 799 8.363e-09 4.578e-07
86 GROWTH 43 410 8.692e-09 4.703e-07
87 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 39 352 9.534e-09 5.099e-07
88 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 123 1848 9.697e-09 5.127e-07
89 NEGATIVE REGULATION OF CELL DEATH 71 872 9.919e-09 5.186e-07
90 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 71 876 1.196e-08 6.184e-07
91 NEURON PROJECTION MORPHOGENESIS 42 402 1.449e-08 7.409e-07
92 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 30 232 1.534e-08 7.758e-07
93 CELL MOTILITY 68 835 2.057e-08 1.008e-06
94 LOCALIZATION OF CELL 68 835 2.057e-08 1.008e-06
95 NEGATIVE REGULATION OF PHOSPHORYLATION 43 422 2.036e-08 1.008e-06
96 DEVELOPMENTAL GROWTH 37 333 2.121e-08 1.028e-06
97 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 55 616 2.358e-08 1.131e-06
98 ACTIVATION OF PROTEIN KINASE ACTIVITY 33 279 2.73e-08 1.296e-06
99 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 50 541 3.511e-08 1.634e-06
100 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 50 541 3.511e-08 1.634e-06
101 POSITIVE REGULATION OF CELL PROLIFERATION 66 814 3.965e-08 1.827e-06
102 REGULATION OF ACTIN FILAMENT BASED PROCESS 35 312 4.013e-08 1.831e-06
103 REGULATION OF OSSIFICATION 25 178 4.706e-08 2.126e-06
104 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 41 404 4.871e-08 2.179e-06
105 REGULATION OF EPITHELIAL CELL MIGRATION 24 166 4.959e-08 2.198e-06
106 FACE DEVELOPMENT 13 50 5.485e-08 2.408e-06
107 REGULATION OF CELL JUNCTION ASSEMBLY 15 68 5.779e-08 2.513e-06
108 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 54 616 5.846e-08 2.519e-06
109 REGULATION OF CYTOSKELETON ORGANIZATION 47 502 6.165e-08 2.632e-06
110 PHOSPHORYLATION 88 1228 6.698e-08 2.833e-06
111 STEM CELL PROLIFERATION 14 60 7.509e-08 3.148e-06
112 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 38 368 9.62e-08 3.997e-06
113 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 21 138 1.391e-07 5.729e-06
114 CELL PART MORPHOGENESIS 54 633 1.423e-07 5.809e-06
115 UROGENITAL SYSTEM DEVELOPMENT 33 299 1.437e-07 5.816e-06
116 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 28 229 1.529e-07 6.133e-06
117 POSITIVE REGULATION OF MAPK CASCADE 44 470 1.638e-07 6.458e-06
118 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 44 470 1.638e-07 6.458e-06
119 SKELETAL SYSTEM DEVELOPMENT 43 455 1.743e-07 6.817e-06
120 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 79 1087 1.882e-07 7.298e-06
121 CELLULAR RESPONSE TO NITROGEN COMPOUND 46 505 1.906e-07 7.328e-06
122 NEGATIVE REGULATION OF CELL DEVELOPMENT 33 303 1.963e-07 7.426e-06
123 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 33 303 1.963e-07 7.426e-06
124 NEURON PROJECTION GUIDANCE 26 205 2.047e-07 7.681e-06
125 REGULATION OF MAP KINASE ACTIVITY 34 319 2.153e-07 8.015e-06
126 AMEBOIDAL TYPE CELL MIGRATION 22 154 2.206e-07 8.146e-06
127 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 30 262 2.381e-07 8.724e-06
128 SENSORY ORGAN DEVELOPMENT 45 493 2.443e-07 8.882e-06
129 POSITIVE REGULATION OF NEURON DIFFERENTIATION 33 306 2.47e-07 8.908e-06
130 RESPONSE TO OXYGEN CONTAINING COMPOUND 94 1381 2.508e-07 8.977e-06
131 EPITHELIAL CELL DIFFERENTIATION 45 495 2.74e-07 9.733e-06
132 ANGIOGENESIS 32 293 2.817e-07 9.928e-06
133 SINGLE ORGANISM BEHAVIOR 38 384 2.872e-07 9.984e-06
134 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 25 2.875e-07 9.984e-06
135 TAXIS 43 464 2.994e-07 1.032e-05
136 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 43 465 3.176e-07 1.086e-05
137 POSITIVE REGULATION OF KINASE ACTIVITY 44 482 3.317e-07 1.119e-05
138 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 19 121 3.3e-07 1.119e-05
139 NEGATIVE REGULATION OF GENE EXPRESSION 99 1493 3.943e-07 1.32e-05
140 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 41 437 4.087e-07 1.358e-05
141 EPITHELIAL CELL DEVELOPMENT 24 186 4.345e-07 1.434e-05
142 CELL FATE COMMITMENT 27 227 4.44e-07 1.455e-05
143 REGULATION OF ADHERENS JUNCTION ORGANIZATION 12 50 4.622e-07 1.504e-05
144 REGULATION OF CELL MATRIX ADHESION 16 90 4.979e-07 1.609e-05
145 REGULATION OF SYNAPSE ORGANIZATION 18 113 5.39e-07 1.73e-05
146 REGULATION OF ENDOTHELIAL CELL MIGRATION 18 114 6.165e-07 1.951e-05
147 AXIS ELONGATION 9 27 6.137e-07 1.951e-05
148 REGULATION OF VASCULATURE DEVELOPMENT 27 233 7.47e-07 2.348e-05
149 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 34 337 7.767e-07 2.426e-05
150 BIOLOGICAL ADHESION 74 1032 7.854e-07 2.436e-05
151 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 30 278 8.515e-07 2.624e-05
152 REGULATION OF CELL MORPHOGENESIS 47 552 9.806e-07 2.982e-05
153 HEAD MORPHOGENESIS 10 36 9.784e-07 2.982e-05
154 FOREBRAIN DEVELOPMENT 35 357 1.048e-06 3.167e-05
155 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 47 554 1.085e-06 3.258e-05
156 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 38 406 1.149e-06 3.424e-05
157 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 19 131 1.155e-06 3.424e-05
158 EPHRIN RECEPTOR SIGNALING PATHWAY 15 85 1.244e-06 3.664e-05
159 CELLULAR RESPONSE TO LIPID 41 457 1.305e-06 3.819e-05
160 SYNAPSE ORGANIZATION 20 145 1.369e-06 3.98e-05
161 REGULATION OF ORGAN MORPHOGENESIS 27 242 1.57e-06 4.538e-05
162 REGULATION OF CELL SUBSTRATE ADHESION 22 173 1.669e-06 4.794e-05
163 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 57 740 1.778e-06 5.075e-05
164 REGULATION OF DEVELOPMENTAL GROWTH 30 289 1.916e-06 5.435e-05
165 WNT SIGNALING PATHWAY 34 351 1.955e-06 5.513e-05
166 MUSCLE TISSUE DEVELOPMENT 29 275 2.064e-06 5.786e-05
167 BEHAVIOR 44 516 2.094e-06 5.833e-05
168 NEGATIVE REGULATION OF MOLECULAR FUNCTION 75 1079 2.109e-06 5.842e-05
169 INOSITOL LIPID MEDIATED SIGNALING 18 124 2.171e-06 5.978e-05
170 ACTIN FILAMENT BASED PROCESS 40 450 2.209e-06 6.047e-05
171 POST EMBRYONIC DEVELOPMENT 15 89 2.275e-06 6.191e-05
172 POSITIVE REGULATION OF LOCOMOTION 38 420 2.601e-06 6.995e-05
173 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 97 1517 2.592e-06 6.995e-05
174 REGULATION OF SYNAPSE ASSEMBLY 14 79 2.662e-06 7.118e-05
175 PROTEIN LOCALIZATION 111 1805 2.874e-06 7.641e-05
176 REGULATION OF SYSTEM PROCESS 43 507 3.138e-06 8.296e-05
177 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 16 103 3.208e-06 8.433e-05
178 REGULATION OF FIBROBLAST PROLIFERATION 14 81 3.622e-06 9.469e-05
179 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 16 104 3.652e-06 9.494e-05
180 RESPONSE TO LIPID 64 888 3.83e-06 9.901e-05
181 RAS PROTEIN SIGNAL TRANSDUCTION 19 143 4.394e-06 0.000113
182 REGULATION OF CELLULAR RESPONSE TO STRESS 53 691 4.66e-06 0.0001191
183 CYTOSKELETON ORGANIZATION 61 838 4.765e-06 0.0001212
184 ENDOTHELIAL CELL DIFFERENTIATION 13 72 4.863e-06 0.000123
185 MUSCLE STRUCTURE DEVELOPMENT 38 432 5.05e-06 0.000127
186 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 8 26 5.205e-06 0.0001302
187 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 34 5.339e-06 0.0001328
188 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 118 1977 5.624e-06 0.0001392
189 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 25 232 7.046e-06 0.0001735
190 BODY MORPHOGENESIS 10 44 7.146e-06 0.000175
191 CELLULAR MACROMOLECULE LOCALIZATION 81 1234 7.205e-06 0.0001755
192 REGULATION OF TRANSPORT 109 1804 7.896e-06 0.0001914
193 EYE DEVELOPMENT 31 326 7.998e-06 0.0001928
194 REGULATION OF CELL CYCLE 66 949 8.711e-06 0.0002089
195 REGULATION OF OSTEOBLAST DIFFERENTIATION 16 112 9.724e-06 0.000232
196 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 23 207 9.822e-06 0.0002332
197 REGULATION OF BINDING 28 283 1.042e-05 0.0002462
198 REGULATION OF STEM CELL DIFFERENTIATION 16 113 1.091e-05 0.0002565
199 REGULATION OF HOMEOSTATIC PROCESS 38 447 1.107e-05 0.0002588
200 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 17 126 1.127e-05 0.0002623
201 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 12 67 1.223e-05 0.0002804
202 REGULATION OF EMBRYONIC DEVELOPMENT 16 114 1.223e-05 0.0002804
203 MODULATION OF SYNAPTIC TRANSMISSION 29 301 1.213e-05 0.0002804
204 CARDIAC MUSCLE TISSUE DEVELOPMENT 18 140 1.238e-05 0.0002824
205 ENDOTHELIUM DEVELOPMENT 14 90 1.287e-05 0.0002894
206 NEUROBLAST PROLIFERATION 8 29 1.285e-05 0.0002894
207 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 15 102 1.284e-05 0.0002894
208 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 10 47 1.338e-05 0.0002992
209 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 16 115 1.369e-05 0.0003048
210 ORGAN GROWTH 12 68 1.432e-05 0.0003173
211 RESPONSE TO FIBROBLAST GROWTH FACTOR 16 116 1.53e-05 0.0003375
212 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 21 184 1.572e-05 0.000345
213 TELENCEPHALON DEVELOPMENT 24 228 1.585e-05 0.0003463
214 RESPONSE TO HORMONE 62 893 1.729e-05 0.000376
215 REGULATION OF GROWTH 48 633 1.765e-05 0.0003819
216 EMBRYONIC ORGAN DEVELOPMENT 35 406 1.82e-05 0.000392
217 ODONTOGENESIS 15 105 1.833e-05 0.000393
218 RESPONSE TO WOUNDING 44 563 1.906e-05 0.0004049
219 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 16 118 1.904e-05 0.0004049
220 NEGATIVE REGULATION OF MAPK CASCADE 18 145 2.013e-05 0.0004258
221 REGULATION OF FAT CELL DIFFERENTIATION 15 106 2.057e-05 0.0004331
222 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 17 133 2.317e-05 0.0004856
223 RESPONSE TO STEROID HORMONE 40 497 2.339e-05 0.0004881
224 MESENCHYME DEVELOPMENT 21 190 2.56e-05 0.0005317
225 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 11 61 2.628e-05 0.0005435
226 RHYTHMIC PROCESS 28 298 2.697e-05 0.0005552
227 MUSCLE CELL DIFFERENTIATION 24 237 3.005e-05 0.0006144
228 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 12 73 3.01e-05 0.0006144
229 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 11 62 3.081e-05 0.000626
230 REGULATION OF RESPONSE TO STRESS 90 1468 3.102e-05 0.0006276
231 PATTERN SPECIFICATION PROCESS 35 418 3.344e-05 0.0006737
232 BRANCH ELONGATION OF AN EPITHELIUM 6 17 3.406e-05 0.0006831
233 REGULATION OF ANATOMICAL STRUCTURE SIZE 38 472 3.697e-05 0.0007382
234 NEGATIVE REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 11 3.821e-05 0.0007597
235 SINGLE ORGANISM CELLULAR LOCALIZATION 61 898 3.841e-05 0.0007606
236 LIPID PHOSPHORYLATION 14 99 3.882e-05 0.0007655
237 REGULATION OF CELLULAR COMPONENT SIZE 30 337 3.925e-05 0.0007705
238 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 10 53 4.055e-05 0.0007928
239 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 7 25 4.078e-05 0.000794
240 IMMUNE SYSTEM DEVELOPMENT 44 582 4.221e-05 0.0008184
241 HEART MORPHOGENESIS 22 212 4.396e-05 0.0008452
242 RESPIRATORY SYSTEM DEVELOPMENT 21 197 4.39e-05 0.0008452
243 BRAIN MORPHOGENESIS 8 34 4.553e-05 0.0008718
244 CELL DEATH 66 1001 4.602e-05 0.0008775
245 VENTRICULAR SEPTUM DEVELOPMENT 10 54 4.8e-05 0.0009117
246 APPENDAGE DEVELOPMENT 19 169 4.848e-05 0.0009133
247 LIMB DEVELOPMENT 19 169 4.848e-05 0.0009133
248 POSITIVE REGULATION OF ENDOCYTOSIS 15 114 4.918e-05 0.0009227
249 POSITIVE REGULATION OF CELL ADHESION 32 376 5.267e-05 0.0009843
250 CELLULAR RESPONSE TO HORMONE STIMULUS 42 552 5.432e-05 0.001011
251 LENS DEVELOPMENT IN CAMERA TYPE EYE 11 66 5.63e-05 0.001044
252 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 10 55 5.659e-05 0.001045
253 NEGATIVE REGULATION OF LOCOMOTION 25 263 5.925e-05 0.00109
254 LUNG MORPHOGENESIS 9 45 6.08e-05 0.001114
255 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 17 144 6.466e-05 0.001175
256 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 17 144 6.466e-05 0.001175
257 RESPONSE TO NITROGEN COMPOUND 58 859 7.032e-05 0.001268
258 HIPPO SIGNALING 7 27 7.026e-05 0.001268
259 NEGATIVE REGULATION OF KINASE ACTIVITY 24 250 7.079e-05 0.001272
260 WOUND HEALING 37 470 7.445e-05 0.001332
261 COGNITION 24 251 7.538e-05 0.001344
262 REGULATION OF ORGANELLE ORGANIZATION 74 1178 7.667e-05 0.001362
263 CELL PROLIFERATION 48 672 7.861e-05 0.001391
264 STEM CELL DIFFERENTIATION 20 190 7.899e-05 0.001392
265 CARDIAC VENTRICLE DEVELOPMENT 14 106 8.344e-05 0.001465
266 ESTABLISHMENT OF LOCALIZATION IN CELL 98 1676 8.435e-05 0.001475
267 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 20 191 8.499e-05 0.001481
268 NEGATIVE REGULATION OF GLIOGENESIS 8 37 8.706e-05 0.001512
269 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 16 134 9.18e-05 0.001582
270 MESENCHYMAL CELL DIFFERENTIATION 16 134 9.18e-05 0.001582
271 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 6 20 9.623e-05 0.001652
272 EXTRACELLULAR STRUCTURE ORGANIZATION 27 304 9.778e-05 0.001673
273 CANONICAL WNT SIGNALING PATHWAY 13 95 0.0001028 0.001751
274 POSITIVE REGULATION OF CELL DEATH 44 605 0.0001034 0.001755
275 REGULATION OF SYNAPTIC TRANSMISSION GABAERGIC 7 29 0.0001152 0.001948
276 CELL CYCLE 80 1316 0.0001158 0.001953
277 MULTICELLULAR ORGANISMAL SIGNALING 15 123 0.0001186 0.001993
278 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 48 684 0.0001201 0.00201
279 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 12 84 0.0001238 0.002057
280 POSITIVE REGULATION OF OSSIFICATION 12 84 0.0001238 0.002057
281 FORMATION OF PRIMARY GERM LAYER 14 110 0.0001252 0.002072
282 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 8 39 0.0001293 0.002125
283 NEGATIVE CHEMOTAXIS 8 39 0.0001293 0.002125
284 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 6 21 0.0001302 0.002133
285 GLAND DEVELOPMENT 32 395 0.0001328 0.002169
286 REGULATION OF CELL ACTIVATION 37 484 0.0001354 0.002202
287 PALLIUM DEVELOPMENT 17 153 0.0001378 0.002233
288 PALATE DEVELOPMENT 12 85 0.000139 0.002246
289 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 9 50 0.0001438 0.002299
290 RESPONSE TO ALCOHOL 30 362 0.0001434 0.002299
291 RHO PROTEIN SIGNAL TRANSDUCTION 9 50 0.0001438 0.002299
292 REGULATION OF ORGAN GROWTH 11 73 0.0001447 0.002305
293 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 32 397 0.0001457 0.002314
294 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 17 154 0.0001492 0.002361
295 POSITIVE REGULATION OF DNA REPLICATION 12 86 0.0001557 0.002457
296 GASTRULATION 17 155 0.0001615 0.002538
297 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 9 51 0.0001684 0.002639
298 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 55 829 0.0001694 0.002645
299 POSITIVE REGULATION OF BINDING 15 127 0.0001703 0.00265
300 REGULATION OF ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 6 22 0.000173 0.002683
301 BONE DEVELOPMENT 17 156 0.0001746 0.002699
302 POSITIVE REGULATION OF CELL CYCLE 28 332 0.0001765 0.002719
303 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 43 602 0.0001833 0.002815
304 REGULATION OF PHOSPHATASE ACTIVITY 15 128 0.0001859 0.002838
305 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 8 41 0.0001871 0.002838
306 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 21 218 0.0001872 0.002838
307 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 8 41 0.0001871 0.002838
308 ACTIVATION OF MAPKK ACTIVITY 9 52 0.0001966 0.002969
309 ESTABLISHMENT OF PROTEIN LOCALIZATION 84 1423 0.0002061 0.003103
310 EPITHELIAL CELL PROLIFERATION 12 89 0.0002168 0.003254
311 PATTERNING OF BLOOD VESSELS 7 32 0.0002237 0.003336
312 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 8 42 0.0002231 0.003336
313 GLIOGENESIS 18 175 0.0002362 0.0035
314 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 18 175 0.0002362 0.0035
315 REPRODUCTIVE SYSTEM DEVELOPMENT 32 408 0.0002388 0.003528
316 NEGATIVE REGULATION OF BINDING 15 131 0.0002405 0.003541
317 PEPTIDYL AMINO ACID MODIFICATION 55 841 0.0002428 0.003553
318 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 14 117 0.0002422 0.003553
319 MAINTENANCE OF CELL NUMBER 15 132 0.0002615 0.003814
320 REGULATION OF NEURON APOPTOTIC PROCESS 19 192 0.0002644 0.003845
321 NEGATIVE REGULATION OF JNK CASCADE 7 33 0.0002742 0.003962
322 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 7 33 0.0002742 0.003962
323 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 24 274 0.0002873 0.004138
324 NEGATIVE REGULATION OF PROTEIN BINDING 11 79 0.0002957 0.004246
325 REGULATION OF B CELL PROLIFERATION 9 55 0.0003052 0.004349
326 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 5 16 0.0003056 0.004349
327 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 5 16 0.0003056 0.004349
328 INTERACTION WITH HOST 15 134 0.0003083 0.004373
329 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 10 67 0.0003115 0.004406
330 REGULATION OF WNT SIGNALING PATHWAY 26 310 0.0003231 0.004542
331 EXOCYTOSIS 26 310 0.0003231 0.004542
332 SKIN DEVELOPMENT 20 211 0.0003264 0.004574
333 REGULATION OF DNA BINDING 12 93 0.0003289 0.004595
334 RESPONSE TO FLUID SHEAR STRESS 7 34 0.0003335 0.004646
335 EPITHELIAL TO MESENCHYMAL TRANSITION 9 56 0.000351 0.00486
336 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 9 56 0.000351 0.00486
337 CHEMICAL HOMEOSTASIS 56 874 0.0003556 0.00491
338 REGULATION OF BLOOD CIRCULATION 25 295 0.0003577 0.004924
339 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 19 197 0.0003665 0.005018
340 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 17 166 0.0003667 0.005018
341 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 20 213 0.0003691 0.005037
342 POSITIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 6 25 0.0003706 0.005042
343 EMBRYONIC ORGAN MORPHOGENESIS 24 279 0.0003746 0.005082
344 ACTIVATION OF MAPK ACTIVITY 15 137 0.0003919 0.005301
345 REGULATION OF MUSCLE CELL DIFFERENTIATION 16 152 0.0003973 0.005358
346 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 9 57 0.0004022 0.005409
347 REGULATION OF RECEPTOR BINDING 5 17 0.0004188 0.005567
348 REGULATION OF ENERGY HOMEOSTASIS 5 17 0.0004188 0.005567
349 REGULATION OF SISTER CHROMATID COHESION 5 17 0.0004188 0.005567
350 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 5 17 0.0004188 0.005567
351 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 16 153 0.0004276 0.005668
352 CARDIOCYTE DIFFERENTIATION 12 96 0.0004422 0.005845
353 NEURAL PRECURSOR CELL PROLIFERATION 10 70 0.0004474 0.005898
354 PROTEIN UBIQUITINATION 43 629 0.0004637 0.006095
355 NEGATIVE REGULATION OF GLIAL CELL DIFFERENTIATION 6 26 0.0004656 0.006102
356 RESPONSE TO INORGANIC SUBSTANCE 35 479 0.0004716 0.006146
357 SKELETAL SYSTEM MORPHOGENESIS 19 201 0.0004713 0.006146
358 KIDNEY EPITHELIUM DEVELOPMENT 14 125 0.000481 0.006236
359 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 40 573 0.0004811 0.006236
360 CORTICAL CYTOSKELETON ORGANIZATION 7 36 0.0004827 0.006239
361 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 13 111 0.0004925 0.006347
362 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 11 84 0.0005072 0.006502
363 TISSUE MIGRATION 11 84 0.0005072 0.006502
364 NEGATIVE REGULATION OF NEURON DEATH 17 171 0.0005177 0.006618
365 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 16 156 0.0005307 0.006729
366 REGULATION OF NEURON DEATH 22 252 0.0005291 0.006729
367 PROTEIN LOCALIZATION TO NUCLEUS 16 156 0.0005307 0.006729
368 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 5 18 0.0005608 0.006991
369 CARDIAC SEPTUM DEVELOPMENT 11 85 0.0005619 0.006991
370 SMOOTH MUSCLE TISSUE DEVELOPMENT 5 18 0.0005608 0.006991
371 NEGATIVE REGULATION OF DEFENSE RESPONSE TO VIRUS 5 18 0.0005608 0.006991
372 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 20 220 0.0005595 0.006991
373 REGULATION OF CELL SIZE 17 172 0.0005536 0.006991
374 POST ANAL TAIL MORPHOGENESIS 5 18 0.0005608 0.006991
375 VESICLE MEDIATED TRANSPORT 73 1239 0.0005711 0.007086
376 POSITIVE REGULATION OF B CELL PROLIFERATION 7 37 0.000575 0.007116
377 REGULATION OF HEART CONTRACTION 20 221 0.0005927 0.007312
378 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 9 60 0.000594 0.007312
379 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 55 873 0.0005991 0.007355
380 REGULATION OF ERK1 AND ERK2 CASCADE 21 238 0.0006106 0.00744
381 POSITIVE REGULATION OF GROWTH 21 238 0.0006106 0.00744
382 REGULATION OF DEPHOSPHORYLATION 16 158 0.0006108 0.00744
383 SECRETION BY CELL 35 486 0.0006126 0.007442
384 SENSORY ORGAN MORPHOGENESIS 21 239 0.0006449 0.007814
385 CARDIAC CHAMBER DEVELOPMENT 15 144 0.0006659 0.007964
386 MEMBRANE DEPOLARIZATION 9 61 0.0006725 0.007964
387 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 8 49 0.000666 0.007964
388 REGULATION OF MEMBRANE POTENTIAL 27 343 0.0006727 0.007964
389 RESPONSE TO EXTERNAL STIMULUS 100 1821 0.0006727 0.007964
390 TUBE FORMATION 14 129 0.0006616 0.007964
391 NUCLEAR IMPORT 14 129 0.0006616 0.007964
392 PROSTATE GLAND GROWTH 4 11 0.0006693 0.007964
393 NEGATIVE REGULATION OF CELL ADHESION 20 223 0.0006642 0.007964
394 CELLULAR RESPONSE TO ACID CHEMICAL 17 175 0.0006745 0.007965
395 COLLAGEN FIBRIL ORGANIZATION 7 38 0.0006808 0.00802
396 CELLULAR RESPONSE TO PEPTIDE 23 274 0.0006902 0.00811
397 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 74 0.000702 0.008196
398 GASTRULATION WITH MOUTH FORMING SECOND 6 28 0.0007116 0.008196
399 POSITIVE REGULATION OF TELOMERASE ACTIVITY 6 28 0.0007116 0.008196
400 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 6 28 0.0007116 0.008196
401 REGULATION OF EXTENT OF CELL GROWTH 12 101 0.0007037 0.008196
402 T CELL MEDIATED IMMUNITY 6 28 0.0007116 0.008196
403 REGULATION OF SPROUTING ANGIOGENESIS 6 28 0.0007116 0.008196
404 REGULATED EXOCYTOSIS 20 224 0.0007026 0.008196
405 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 5 19 0.0007362 0.008459
406 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 9 62 0.0007593 0.008698
407 REGULATION OF PEPTIDE SECRETION 19 209 0.0007608 0.008698
408 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 8 50 0.0007655 0.00873
409 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 18 193 0.0007696 0.008756
410 REGIONALIZATION 25 311 0.0007763 0.008811
411 SENSORY PERCEPTION OF PAIN 10 75 0.0007815 0.008848
412 MUSCLE ORGAN DEVELOPMENT 23 277 0.0008009 0.009045
413 LIPID MODIFICATION 19 210 0.000806 0.00908
414 REGULATION OF RECEPTOR ACTIVITY 13 117 0.0008155 0.009166
415 CONNECTIVE TISSUE DEVELOPMENT 18 194 0.0008175 0.009166
416 POSITIVE REGULATION OF CELL DIVISION 14 132 0.0008321 0.009307
417 CIRCULATORY SYSTEM PROCESS 28 366 0.0008402 0.009353
418 REGULATION OF CIRCADIAN RHYTHM 12 103 0.0008395 0.009353
419 REGULATION OF MUSCLE ADAPTATION 9 63 0.0008549 0.009494
420 EPIDERMIS MORPHOGENESIS 6 29 0.0008672 0.009569
421 STEM CELL DIVISION 6 29 0.0008672 0.009569
422 EAR DEVELOPMENT 18 195 0.0008679 0.009569
423 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 8 51 0.0008766 0.009643
424 REGULATION OF ION TRANSPORT 40 592 0.0009032 0.009912
NumGOOverlapSizeP ValueAdj. P Value
1 MOLECULAR FUNCTION REGULATOR 114 1353 1.769e-14 1.644e-11
2 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 41 328 1.028e-10 4.774e-08
3 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 32 228 6.434e-10 1.992e-07
4 ENZYME BINDING 121 1737 8.89e-10 2.065e-07
5 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 92 1199 1.158e-09 2.151e-07
6 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 56 629 1.935e-08 2.386e-06
7 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 35 303 1.908e-08 2.386e-06
8 ENZYME REGULATOR ACTIVITY 75 959 2.055e-08 2.386e-06
9 REGULATORY REGION NUCLEIC ACID BINDING 66 818 4.773e-08 4.927e-06
10 GROWTH FACTOR RECEPTOR BINDING 19 129 9.093e-07 7.679e-05
11 MACROMOLECULAR COMPLEX BINDING 93 1399 8.281e-07 7.679e-05
12 PROTEIN KINASE ACTIVITY 52 640 1.076e-06 7.686e-05
13 GTPASE BINDING 31 295 9.972e-07 7.686e-05
14 RECEPTOR BINDING 95 1476 2.522e-06 0.0001673
15 KINASE BINDING 47 606 1.213e-05 0.0006629
16 KINASE ACTIVITY 60 842 1.094e-05 0.0006629
17 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 46 588 1.205e-05 0.0006629
18 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 24 226 1.368e-05 0.000706
19 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 36 420 1.57e-05 0.0007677
20 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 13 81 1.848e-05 0.0007853
21 DOUBLE STRANDED DNA BINDING 55 764 1.924e-05 0.0007853
22 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 12 70 1.944e-05 0.0007853
23 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 15 105 1.833e-05 0.0007853
24 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 17 133 2.317e-05 0.0008609
25 ZINC ION BINDING 75 1155 2.311e-05 0.0008609
26 PROTEIN DOMAIN SPECIFIC BINDING 47 624 2.554e-05 0.0009127
27 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 29 315 2.846e-05 0.0009792
28 EPHRIN RECEPTOR BINDING 7 24 3.041e-05 0.001009
29 GROWTH FACTOR BINDING 16 123 3.214e-05 0.001029
30 PROTEIN DIMERIZATION ACTIVITY 74 1149 3.441e-05 0.001066
31 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 11 64 4.191e-05 0.001256
32 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 19 168 4.467e-05 0.001297
33 ACTIN BINDING 33 393 5.267e-05 0.001483
34 CYTOKINE BINDING 13 92 7.339e-05 0.002005
35 ENZYME ACTIVATOR ACTIVITY 37 471 7.779e-05 0.002007
36 TRANSCRIPTION FACTOR BINDING 40 524 7.575e-05 0.002007
37 PROTEIN TYROSINE KINASE ACTIVITY 19 176 8.429e-05 0.002116
38 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 64 992 0.0001123 0.002745
39 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 12 86 0.0001557 0.00371
40 PHOSPHATASE REGULATOR ACTIVITY 12 87 0.0001742 0.004046
41 RECEPTOR SIGNALING PROTEIN ACTIVITY 18 172 0.0001903 0.004312
42 CYTOSKELETAL PROTEIN BINDING 54 819 0.0002261 0.004422
43 KINASE INHIBITOR ACTIVITY 12 89 0.0002168 0.004422
44 PROTEIN KINASE A BINDING 8 42 0.0002231 0.004422
45 CAMP BINDING 6 23 0.0002262 0.004422
46 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 9 53 0.0002285 0.004422
47 SEQUENCE SPECIFIC DNA BINDING 65 1037 0.0002239 0.004422
48 CORE PROMOTER PROXIMAL REGION DNA BINDING 30 371 0.0002198 0.004422
49 PROTEIN SERINE THREONINE KINASE ACTIVITY 34 445 0.0002521 0.00478
50 IDENTICAL PROTEIN BINDING 73 1209 0.0002833 0.005264
51 TRANSFORMING GROWTH FACTOR BETA BINDING 5 16 0.0003056 0.005567
52 RAB GTPASE BINDING 14 120 0.0003158 0.005642
53 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 27 329 0.0003532 0.006191
54 RIBONUCLEOTIDE BINDING 103 1860 0.0004152 0.007143
55 CYCLIC NUCLEOTIDE BINDING 7 36 0.0004827 0.008154
56 CELL ADHESION MOLECULE BINDING 18 186 0.0004971 0.008246
57 STEROID HORMONE RECEPTOR ACTIVITY 9 59 0.0005232 0.008527
NumGOOverlapSizeP ValueAdj. P Value
1 SYNAPSE 66 754 1.973e-09 7.145e-07
2 CELL PROJECTION 122 1786 2.447e-09 7.145e-07
3 NEURON PROJECTION 74 942 2.138e-08 4.161e-06
4 MEMBRANE REGION 84 1134 3.232e-08 4.719e-06
5 NEURON PART 89 1265 1.279e-07 1.494e-05
6 PLASMA MEMBRANE REGION 69 929 5.383e-07 4.888e-05
7 SYNAPSE PART 51 610 5.859e-07 4.888e-05
8 SOMATODENDRITIC COMPARTMENT 53 650 7.597e-07 5.546e-05
9 CYTOSKELETON 121 1967 9.351e-07 6.068e-05
10 EXCITATORY SYNAPSE 23 197 4.287e-06 0.0002504
11 MICROTUBULE ORGANIZING CENTER 49 623 5.424e-06 0.000288
12 CELL JUNCTION 77 1151 6.266e-06 0.0003049
13 PLASMA MEMBRANE RAFT 14 86 7.494e-06 0.0003367
14 MEMBRANE MICRODOMAIN 28 288 1.444e-05 0.0006024
15 POSTSYNAPSE 33 378 2.434e-05 0.0009428
16 INTRACELLULAR VESICLE 80 1259 2.617e-05 0.0009428
17 CELL PROJECTION PART 64 946 2.796e-05 0.0009428
18 GOLGI APPARATUS 89 1445 2.906e-05 0.0009428
19 CELL LEADING EDGE 31 350 3.232e-05 0.0009935
20 APICAL JUNCTION COMPLEX 16 128 5.264e-05 0.001537
21 MICROTUBULE CYTOSKELETON 69 1068 5.797e-05 0.001612
22 LAMELLIPODIUM 19 172 6.171e-05 0.001638
23 DENDRITE 36 451 7.007e-05 0.001779
24 CELL CELL JUNCTION 32 383 7.48e-05 0.00182
25 CYTOPLASMIC VESICLE PART 44 601 8.89e-05 0.002077
26 PML BODY 13 97 0.0001275 0.002865
27 RECEPTOR COMPLEX 28 327 0.0001368 0.00296
28 CENTROSOME 37 487 0.0001532 0.003195
29 TRANSCRIPTION FACTOR COMPLEX 26 298 0.0001739 0.003502
30 PRESYNAPSE 25 283 0.00019 0.003698
31 PERINUCLEAR REGION OF CYTOPLASM 45 642 0.0001996 0.00376
32 NEURON SPINE 14 121 0.0003442 0.006283
33 AXON 32 418 0.0003661 0.006472
34 PLASMA MEMBRANE PROTEIN COMPLEX 37 510 0.0003768 0.006472
35 VESICLE MEMBRANE 37 512 0.0004059 0.006772
36 ENDOPLASMIC RETICULUM LUMEN 19 201 0.0004713 0.007646
37 EXTRACELLULAR MATRIX 32 426 0.0005081 0.00802

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 25 139 2.511e-10 9.942e-09
2 Focal_adhesion_hsa04510 30 199 3.824e-10 9.942e-09
3 MAPK_signaling_pathway_hsa04010 34 295 3.217e-08 5.575e-07
4 Regulation_of_actin_cytoskeleton_hsa04810 22 208 3.285e-05 0.0004271
5 Hippo_signaling_pathway_hsa04390 18 154 4.548e-05 0.0004517
6 Tight_junction_hsa04530 19 170 5.258e-05 0.0004517
7 Ras_signaling_pathway_hsa04014 23 232 6.081e-05 0.0004517
8 PI3K_Akt_signaling_pathway_hsa04151 30 352 8.71e-05 0.0005662
9 Endocytosis_hsa04144 23 244 0.0001308 0.000756
10 Rap1_signaling_pathway_hsa04015 20 206 0.0002379 0.001237
11 cAMP_signaling_pathway_hsa04024 19 198 0.0003906 0.001847
12 Wnt_signaling_pathway_hsa04310 15 146 0.0007691 0.003333
13 ECM_receptor_interaction_hsa04512 10 82 0.00157 0.006281
14 TGF_beta_signaling_pathway_hsa04350 10 84 0.001887 0.007009
15 Adherens_junction_hsa04520 9 72 0.002235 0.007749
16 FoxO_signaling_pathway_hsa04068 13 132 0.00246 0.007994
17 p53_signaling_pathway_hsa04115 8 68 0.005619 0.01719
18 ErbB_signaling_pathway_hsa04012 9 85 0.006842 0.01976
19 Cellular_senescence_hsa04218 13 160 0.01218 0.03332
20 Cell_adhesion_molecules_.CAMs._hsa04514 12 145 0.01368 0.03479
21 cGMP_PKG_signaling_pathway_hsa04022 13 163 0.01405 0.03479
22 mTOR_signaling_pathway_hsa04150 12 151 0.01831 0.04328
23 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.02725 0.06162
24 TNF_signaling_pathway_hsa04668 9 108 0.02916 0.06317
25 ABC_transporters_hsa02010 5 45 0.03301 0.06866
26 Sphingolipid_signaling_pathway_hsa04071 9 118 0.04721 0.0934
27 Apelin_signaling_pathway_hsa04371 10 137 0.0485 0.0934
28 Jak_STAT_signaling_pathway_hsa04630 11 162 0.06101 0.1133
29 Phospholipase_D_signaling_pathway_hsa04072 10 146 0.06855 0.1229
30 AMPK_signaling_pathway_hsa04152 8 121 0.1122 0.1945
31 Hedgehog_signaling_pathway_hsa04340 4 47 0.1177 0.1975
32 Oocyte_meiosis_hsa04114 8 124 0.1243 0.2019
33 Calcium_signaling_pathway_hsa04020 10 182 0.1942 0.3061
34 Cell_cycle_hsa04110 7 124 0.2284 0.3493
35 Mitophagy_animal_hsa04137 4 65 0.262 0.3893
36 Gap_junction_hsa04540 5 88 0.2762 0.399
37 Cytokine_cytokine_receptor_interaction_hsa04060 13 270 0.286 0.402
38 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.3631 0.4928
39 Lysosome_hsa04142 6 123 0.3696 0.4928
40 Autophagy_animal_hsa04140 6 128 0.4055 0.5272
41 Peroxisome_hsa04146 4 83 0.4256 0.5398
42 Ferroptosis_hsa04216 2 40 0.4792 0.5933
43 HIF_1_signaling_pathway_hsa04066 4 100 0.571 0.6825
44 Notch_signaling_pathway_hsa04330 2 48 0.5775 0.6825
45 VEGF_signaling_pathway_hsa04370 2 59 0.6894 0.7966
46 Phagosome_hsa04145 5 152 0.7321 0.8191
47 Necroptosis_hsa04217 5 164 0.7898 0.8556
48 NF_kappa_B_signaling_pathway_hsa04064 2 95 0.898 0.9498
49 Apoptosis_hsa04210 3 138 0.9179 0.9498
50 Neuroactive_ligand_receptor_interaction_hsa04080 7 278 0.9315 0.9498

Quest ID: 323a988796b9643a6d38c8dc867525b7